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New 55Co-labeled Albumin-Binding Folate Derivatives as Potential PET Agents for Folate Receptor Imaging.

Radford LL, Fernandez S, Beacham R, El Sayed R, Farkas R, Benešová M, Müller C, Lapi SE.

Pharmaceuticals (Basel). 2019 Nov 8;12(4). pii: E166. doi: 10.3390/ph12040166.


Development of Novel PSMA Ligands for Imaging and Therapy with Copper Isotopes.

Dos Santos JC, Beijer B, Bauder-Wüst U, Schäfer M, Leotta K, Eder M, Benešová M, Kleist C, Giesel F, Kratochwil C, Kopka K, Haberkorn U, Mier W.

J Nucl Med. 2019 Sep 20. pii: jnumed.119.229054. doi: 10.2967/jnumed.119.229054. [Epub ahead of print]


Preclinical investigations and first-in-human application of 152Tb-PSMA-617 for PET/CT imaging of prostate cancer.

Müller C, Singh A, Umbricht CA, Kulkarni HR, Johnston K, Benešová M, Senftleben S, Müller D, Vermeulen C, Schibli R, Köster U, van der Meulen NP, Baum RP.

EJNMMI Res. 2019 Jul 25;9(1):68. doi: 10.1186/s13550-019-0538-1.


Internal radiation dosimetry of a 152Tb-labeled antibody in tumor-bearing mice.

Cicone F, Gnesin S, Denoël T, Stora T, van der Meulen NP, Müller C, Vermeulen C, Benešová M, Köster U, Johnston K, Amato E, Auditore L, Coukos G, Stabin M, Schaefer N, Viertl D, Prior JO.

EJNMMI Res. 2019 Jun 11;9(1):53. doi: 10.1186/s13550-019-0524-7.


Implementation of a new separation method to produce qualitatively improved 64 Cu.

van der Meulen NP, Hasler R, Blanc A, Farkas R, Benešová M, Talip Z, Müller C, Schibli R.

J Labelled Comp Radiopharm. 2019 Jun 30;62(8):460-470. doi: 10.1002/jlcr.3730.


Persistent reduction of mitral regurgitation by implantation of a transannular mitral bridge: durability and effectiveness of the repair at 2 years-results of a prospective trial†.

Cerny S, Benesova M, Skalsky I, Patel NC, Subramanian VA.

Eur J Cardiothorac Surg. 2019 May 1;55(5):867-873. doi: 10.1093/ejcts/ezy423.


Visualisation of interstitial lung disease by molecular imaging of integrin αvβ3 and somatostatin receptor 2.

Schniering J, Benešová M, Brunner M, Haller S, Cohrs S, Frauenfelder T, Vrugt B, Feghali-Bostwick CA, Schibli R, Distler O, Mueller C, Maurer B.

Ann Rheum Dis. 2019 Feb;78(2):218-227. doi: 10.1136/annrheumdis-2018-214322. Epub 2018 Nov 17. Erratum in: Ann Rheum Dis. 2019 Jun;78(6):e60.


Design and Preclinical Evaluation of an Albumin-Binding PSMA Ligand for 64Cu-Based PET Imaging.

Umbricht CA, Benešová M, Hasler R, Schibli R, van der Meulen NP, Müller C.

Mol Pharm. 2018 Dec 3;15(12):5556-5564. doi: 10.1021/acs.molpharmaceut.8b00712. Epub 2018 Oct 30.


In Vivo Labeling of Plasma Proteins for Imaging of Enhanced Vascular Permeability in the Lungs.

Schniering J, Borgna F, Siwowska K, Benešová M, Cohrs S, Hasler R, van der Meulen NP, Maurer B, Schibli R, Müller C.

Mol Pharm. 2018 Nov 5;15(11):4995-5004. doi: 10.1021/acs.molpharmaceut.8b00606. Epub 2018 Sep 28.


Analysis of short wavelength infrared radiation during laser welding of plastics.

Martan J, Tesař J, Kučera M, Honnerová P, Benešová M, Honner M.

Appl Opt. 2018 Jun 20;57(18):D145-D154. doi: 10.1364/AO.57.00D145.


Preclinical Development of Novel PSMA-Targeting Radioligands: Modulation of Albumin-Binding Properties To Improve Prostate Cancer Therapy.

Umbricht CA, Benešová M, Schibli R, Müller C.

Mol Pharm. 2018 Jun 4;15(6):2297-2306. doi: 10.1021/acs.molpharmaceut.8b00152. Epub 2018 May 2.


Albumin-Binding PSMA Ligands: Optimization of the Tissue Distribution Profile.

Benešová M, Umbricht CA, Schibli R, Müller C.

Mol Pharm. 2018 Mar 5;15(3):934-946. doi: 10.1021/acs.molpharmaceut.7b00877. Epub 2018 Feb 5.


Clinical Translation and First In-Human Use of [44Sc]Sc-PSMA-617 for PET Imaging of Metastasized Castrate-Resistant Prostate Cancer.

Eppard E, de la Fuente A, Benešová M, Khawar A, Bundschuh RA, Gärtner FC, Kreppel B, Kopka K, Essler M, Rösch F.

Theranostics. 2017 Sep 26;7(18):4359-4369. doi: 10.7150/thno.20586. eCollection 2017.


Synthesis, Radiolabeling, and Characterization of Plasma Protein-Binding Ligands: Potential Tools for Modulation of the Pharmacokinetic Properties of (Radio)Pharmaceuticals.

Müller C, Farkas R, Borgna F, Schmid RM, Benešová M, Schibli R.

Bioconjug Chem. 2017 Sep 20;28(9):2372-2383. doi: 10.1021/acs.bioconjchem.7b00378. Epub 2017 Sep 12.


Therapeutic Radiometals Beyond 177Lu and 90Y: Production and Application of Promising α-Particle, β--Particle, and Auger Electron Emitters.

Müller C, van der Meulen NP, Benešová M, Schibli R.

J Nucl Med. 2017 Sep;58(Suppl 2):91S-96S. doi: 10.2967/jnumed.116.186825. Review.


Glu-Ureido-Based Inhibitors of Prostate-Specific Membrane Antigen: Lessons Learned During the Development of a Novel Class of Low-Molecular-Weight Theranostic Radiotracers.

Kopka K, Benešová M, Bařinka C, Haberkorn U, Babich J.

J Nucl Med. 2017 Sep;58(Suppl 2):17S-26S. doi: 10.2967/jnumed.116.186775. Review.


Clinical evaluation of the radiolanthanide terbium-152: first-in-human PET/CT with 152Tb-DOTATOC.

Baum RP, Singh A, Benešová M, Vermeulen C, Gnesin S, Köster U, Johnston K, Müller D, Senftleben S, Kulkarni HR, Türler A, Schibli R, Prior JO, van der Meulen NP, Müller C.

Dalton Trans. 2017 Oct 31;46(42):14638-14646. doi: 10.1039/c7dt01936j.


The disadvantages of being a hybrid during drought: A combined analysis of plant morphology, physiology and leaf proteome in maize.

Holá D, Benešová M, Fischer L, Haisel D, Hnilička F, Hniličková H, Jedelský PL, Kočová M, Procházková D, Rothová O, Tůmová L, Wilhelmová N.

PLoS One. 2017 Apr 18;12(4):e0176121. doi: 10.1371/journal.pone.0176121. eCollection 2017.


DNA hypomethylation and aberrant expression of the human endogenous retrovirus ERVWE1/syncytin-1 in seminomas.

Benešová M, Trejbalová K, Kovářová D, Vernerová Z, Hron T, Kučerová D, Hejnar J.

Retrovirology. 2017 Mar 17;14(1):20. doi: 10.1186/s12977-017-0342-9.


Overexpression of TET dioxygenases in seminomas associates with low levels of DNA methylation and hydroxymethylation.

Benešová M, Trejbalová K, Kučerová D, Vernerová Z, Hron T, Szabó A, Amouroux R, Klézl P, Hajkova P, Hejnar J.

Mol Carcinog. 2017 Aug;56(8):1837-1850. doi: 10.1002/mc.22638. Epub 2017 May 24.


44Sc-PSMA-617 for radiotheragnostics in tandem with 177Lu-PSMA-617-preclinical investigations in comparison with 68Ga-PSMA-11 and 68Ga-PSMA-617.

Umbricht CA, Benešová M, Schmid RM, Türler A, Schibli R, van der Meulen NP, Müller C.

EJNMMI Res. 2017 Dec;7(1):9. doi: 10.1186/s13550-017-0257-4. Epub 2017 Jan 19.


Preclinical Comparison of Albumin-Binding Radiofolates: Impact of Linker Entities on the in Vitro and in Vivo Properties.

Siwowska K, Haller S, Bortoli F, Benešová M, Groehn V, Bernhardt P, Schibli R, Müller C.

Mol Pharm. 2017 Feb 6;14(2):523-532. doi: 10.1021/acs.molpharmaceut.6b01010. Epub 2017 Jan 17.


47Sc as useful β--emitter for the radiotheragnostic paradigm: a comparative study of feasible production routes.

Domnanich KA, Müller C, Benešová M, Dressler R, Haller S, Köster U, Ponsard B, Schibli R, Türler A, van der Meulen NP.

EJNMMI Radiopharm Chem. 2017;2(1):5. doi: 10.1186/s41181-017-0024-x. Epub 2017 Jun 2.


Preclinical Evaluation of 18F-PSMA-1007, a New Prostate-Specific Membrane Antigen Ligand for Prostate Cancer Imaging.

Cardinale J, Schäfer M, Benešová M, Bauder-Wüst U, Leotta K, Eder M, Neels OC, Haberkorn U, Giesel FL, Kopka K.

J Nucl Med. 2017 Mar;58(3):425-431. doi: 10.2967/jnumed.116.181768. Epub 2016 Oct 27.


(18)F-Labelled PSMA-1007 shows similarity in structure, biodistribution and tumour uptake to the theragnostic compound PSMA-617.

Giesel FL, Cardinale J, Schäfer M, Neels O, Benešová M, Mier W, Haberkorn U, Kopka K, Kratochwil C.

Eur J Nucl Med Mol Imaging. 2016 Sep;43(10):1929-30. doi: 10.1007/s00259-016-3447-9. Epub 2016 Jun 25. No abstract available.


Design of Internalizing PSMA-specific Glu-ureido-based Radiotherapeuticals.

Wüstemann T, Bauder-Wüst U, Schäfer M, Eder M, Benesova M, Leotta K, Kratochwil C, Haberkorn U, Kopka K, Mier W.

Theranostics. 2016 Apr 28;6(8):1085-95. doi: 10.7150/thno.13448. eCollection 2016.


PSMA-Targeted Radionuclide Therapy of Metastatic Castration-Resistant Prostate Cancer with 177Lu-Labeled PSMA-617.

Kratochwil C, Giesel FL, Stefanova M, Benešová M, Bronzel M, Afshar-Oromieh A, Mier W, Eder M, Kopka K, Haberkorn U.

J Nucl Med. 2016 Aug;57(8):1170-6. doi: 10.2967/jnumed.115.171397. Epub 2016 Mar 16.


Linker Modification Strategies To Control the Prostate-Specific Membrane Antigen (PSMA)-Targeting and Pharmacokinetic Properties of DOTA-Conjugated PSMA Inhibitors.

Benešová M, Bauder-Wüst U, Schäfer M, Klika KD, Mier W, Haberkorn U, Kopka K, Eder M.

J Med Chem. 2016 Mar 10;59(5):1761-75. doi: 10.1021/acs.jmedchem.5b01210. Epub 2016 Mar 1.


The Theranostic PSMA Ligand PSMA-617 in the Diagnosis of Prostate Cancer by PET/CT: Biodistribution in Humans, Radiation Dosimetry, and First Evaluation of Tumor Lesions.

Afshar-Oromieh A, Hetzheim H, Kratochwil C, Benesova M, Eder M, Neels OC, Eisenhut M, Kübler W, Holland-Letz T, Giesel FL, Mier W, Kopka K, Haberkorn U.

J Nucl Med. 2015 Nov;56(11):1697-705. doi: 10.2967/jnumed.115.161299. Epub 2015 Aug 20.


Preclinical Evaluation of a Tailor-Made DOTA-Conjugated PSMA Inhibitor with Optimized Linker Moiety for Imaging and Endoradiotherapy of Prostate Cancer.

Benešová M, Schäfer M, Bauder-Wüst U, Afshar-Oromieh A, Kratochwil C, Mier W, Haberkorn U, Kopka K, Eder M.

J Nucl Med. 2015 Jun;56(6):914-20. doi: 10.2967/jnumed.114.147413. Epub 2015 Apr 16.


Analysis of Human Milk Composition After Preterm Delivery With and Without Fortification.

Krcho P, Vojtova V, Benesova M.

Matern Child Health J. 2015 Aug;19(8):1657-61. doi: 10.1007/s10995-015-1681-6.


[¹⁷⁷Lu]Lutetium-labelled PSMA ligand-induced remission in a patient with metastatic prostate cancer.

Kratochwil C, Giesel FL, Eder M, Afshar-Oromieh A, Benešová M, Mier W, Kopka K, Haberkorn U.

Eur J Nucl Med Mol Imaging. 2015 May;42(6):987-8. doi: 10.1007/s00259-014-2978-1. Epub 2015 Jan 9. No abstract available.


Toll-like receptors expressed on embryonic macrophages couple inflammatory signals to iron metabolism during early ontogenesis.

Balounová J, Vavrochová T, Benešová M, Ballek O, Kolář M, Filipp D.

Eur J Immunol. 2014 May;44(5):1491-502. doi: 10.1002/eji.201344040. Epub 2014 Feb 18.


Quantitative proteomics analysis of macrophage-derived lipid rafts reveals induction of autophagy pathway at the early time of Francisella tularensis LVS infection.

Härtlova A, Link M, Balounova J, Benesova M, Resch U, Straskova A, Sobol M, Philimonenko A, Hozak P, Krocova Z, Gekara N, Filipp D, Stulik J.

J Proteome Res. 2014 Feb 7;13(2):796-804. doi: 10.1021/pr4008656. Epub 2014 Jan 7.


The physiology and proteomics of drought tolerance in maize: early stomatal closure as a cause of lower tolerance to short-term dehydration?

Benešová M, Holá D, Fischer L, Jedelský PL, Hnilička F, Wilhelmová N, Rothová O, Kočová M, Procházková D, Honnerová J, Fridrichová L, Hniličková H.

PLoS One. 2012;7(6):e38017. doi: 10.1371/journal.pone.0038017. Epub 2012 Jun 13.


Eosinophils from patients with type 1 diabetes mellitus express high level of myeloid alpha-defensins and myeloperoxidase.

Neuwirth A, Dobeš J, Oujezdská J, Ballek O, Benešová M, Sumník Z, Včeláková J, Koloušková S, Obermannová B, Kolář M, Stechová K, Filipp D.

Cell Immunol. 2012;273(2):158-63. doi: 10.1016/j.cellimm.2011.12.001. Epub 2012 Jan 2.


[Antithrombotic therapy after heart valve surgery--current evidence and future trends].

Benesová M.

Cas Lek Cesk. 2011;150(4-5):229-35. Review. Czech.


The effect of DYS-14 copy number variations on extracellular fetal DNA quantification in maternal circulation.

Hromadnikova I, Benesova M, Zejskova L, Stehnova J, Doucha J, Sedlacek P, Dlouha K, Krofta L.

DNA Cell Biol. 2009 Jul;28(7):351-8. doi: 10.1089/dna.2009.0855.


Alcohol and colorectal cancer: the role of alcohol dehydrogenase 1C polymorphism.

Homann N, König IR, Marks M, Benesova M, Stickel F, Millonig G, Mueller S, Seitz HK.

Alcohol Clin Exp Res. 2009 Mar;33(3):551-6. doi: 10.1111/j.1530-0277.2008.00868.x. Epub 2008 Dec 19.


Recovery of maize (Zea mays L.) inbreds and hybrids from chilling stress of various duration: photosynthesis and antioxidant enzymes.

Holá D, Kocová M, Rothová O, Wilhelmová N, Benesová M.

J Plant Physiol. 2007 Jul;164(7):868-77. Epub 2006 Aug 1.


Alcohol dehydrogenase 1C*1 allele is a genetic marker for alcohol-associated cancer in heavy drinkers.

Homann N, Stickel F, König IR, Jacobs A, Junghanns K, Benesova M, Schuppan D, Himsel S, Zuber-Jerger I, Hellerbrand C, Ludwig D, Caselmann WH, Seitz HK.

Int J Cancer. 2006 Apr 15;118(8):1998-2002.


Risk factors in alcohol associated breast cancer: alcohol dehydrogenase polymorphism and estrogens.

Coutelle C, Höhn B, Benesova M, Oneta CM, Quattrochi P, Roth HJ, Schmidt-Gayk H, Schneeweiss A, Bastert G, Seitz HK.

Int J Oncol. 2004 Oct;25(4):1127-32.


Increased cancer risk in heavy drinkers with the alcohol dehydrogenase 1C*1 allele, possibly due to salivary acetaldehyde.

Visapää JP, Götte K, Benesova M, Li J, Homann N, Conradt C, Inoue H, Tisch M, Hörrmann K, Väkeväinen S, Salaspuro M, Seitz HK.

Gut. 2004 Jun;53(6):871-6.


[Caspases--a target for intervention in diseases which are still difficult to treat].

Benes L, Benesová M.

Ceska Slov Farm. 2004 Jan;53(1):18-26. Review. Czech.


Thickness measurement of thin dielectric films by evanescent total reflection fluorescence.

Benesová M, Tománek P.

J Microsc. 1999 May-Jun;194(Pt 2-3):434-8.


Spinach chloroplast ATP-dependent endopeptidase: Ti-like protease.

Benesová M, Durcová G, Kuzela S, Kutejová E, Psenák M.

Phytochemistry. 1996 Jan;41(1):65-9.


Biotransformation and in vitro activity of an arabinosylcytosine 5'-chloro-5'-deoxy analog.

Novotný L, Reichelová V, Balázová E, Scheithauer W, Benesová M, Ujházy V.

Anticancer Drugs. 1991 Oct;2(5):495-502.


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