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Items: 1 to 50 of 75

1.

A Synthetic Bottle-brush Polyelectrolyte Reduces Friction and Wear of Intact and Previously Worn Cartilage.

Lakin BA, Cooper BG, Zakaria L, Grasso DJ, Wathier M, Bendele AM, Freedman JD, Snyder BD, Grinstaff MW.

ACS Biomater Sci Eng. 2019 Jun 10;5(6):3060-3067. doi: 10.1021/acsbiomaterials.9b00085. Epub 2019 May 17.

2.

Physical inactivity and knee osteoarthritis in guinea pigs.

Wallace IJ, Bendele AM, Riew G, Frank EH, Hung HH, Holowka NB, Bolze AS, Venable EM, Yegian AK, Dingwall HL, Carmody RN, Grodzinsky AJ, Lieberman DE.

Osteoarthritis Cartilage. 2019 Nov;27(11):1721-1728. doi: 10.1016/j.joca.2019.07.005. Epub 2019 Jul 11.

PMID:
31302235
3.

A synthetic polymeric biolubricant imparts chondroprotection in a rat meniscal tear model.

Wathier M, Lakin BA, Cooper BG, Bansal PN, Bendele AM, Entezari V, Suzuki H, Snyder BD, Grinstaff MW.

Biomaterials. 2018 Nov;182:13-20. doi: 10.1016/j.biomaterials.2018.08.009. Epub 2018 Aug 7.

4.

The selective cathepsin K inhibitor MIV-711 attenuates joint pathology in experimental animal models of osteoarthritis.

Lindström E, Rizoska B, Tunblad K, Edenius C, Bendele AM, Maul D, Larson M, Shah N, Yoder Otto V, Jerome C, Grabowska U.

J Transl Med. 2018 Mar 9;16(1):56. doi: 10.1186/s12967-018-1425-7.

5.

Toxicology Evaluation of Drugs Administered via Uncommon Routes: Intranasal, Intraocular, Intrathecal/Intraspinal, and Intra-Articular.

Emami A, Tepper J, Short B, Yaksh TL, Bendele AM, Ramani T, Cisternas AF, Chang JH, Mellon RD.

Int J Toxicol. 2018 Jan/Feb;37(1):4-27. doi: 10.1177/1091581817741840. Epub 2017 Dec 21.

6.

Analgesic and anti-inflammatory properties of novel, selective, and potent EP4 receptor antagonists.

Chandrasekhar S, Yu XP, Harvey AK, Oskins JL, Lin C, Wang X, Blanco MJ, Fisher MJ, Kuklish SL, Schiffler MA, Vetman T, Warshawsky AM, York JS, Bendele AM, Chambers MG.

Pharmacol Res Perspect. 2017 May 14;5(3):e00316. doi: 10.1002/prp2.316. eCollection 2017 Jun.

7.

Beneficial effects of natural eggshell membrane (NEM) on multiple indices of arthritis in collagen-induced arthritic rats.

Wedekind KJ, Ruff KJ, Atwell CA, Evans JL, Bendele AM.

Mod Rheumatol. 2017 Sep;27(5):838-848. doi: 10.1080/14397595.2016.1259729. Epub 2016 Dec 21.

PMID:
27846748
8.

Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear model.

LaBranche TP, Bendele AM, Omura BC, Gropp KE, Hurst SI, Bagi CM, Cummings TR, Grantham LE 2nd, Shelton DL, Zorbas MA.

Ann Rheum Dis. 2017 Jan;76(1):295-302. doi: 10.1136/annrheumdis-2015-208913. Epub 2016 Jul 5.

9.
10.

Sustained efficacy of a single intra-articular dose of FX006 in a rat model of repeated localized knee arthritis.

Kumar A, Bendele AM, Blanks RC, Bodick N.

Osteoarthritis Cartilage. 2015 Jan;23(1):151-60. doi: 10.1016/j.joca.2014.09.019. Epub 2014 Sep 26.

11.

The OARSI histopathology initiative - recommendations for histological assessments of osteoarthritis in the rat.

Gerwin N, Bendele AM, Glasson S, Carlson CS.

Osteoarthritis Cartilage. 2010 Oct;18 Suppl 3:S24-34. doi: 10.1016/j.joca.2010.05.030.

12.

A new class of potent matrix metalloproteinase 13 inhibitors for potential treatment of osteoarthritis: Evidence of histologic and clinical efficacy without musculoskeletal toxicity in rat models.

Baragi VM, Becher G, Bendele AM, Biesinger R, Bluhm H, Boer J, Deng H, Dodd R, Essers M, Feuerstein T, Gallagher BM Jr, Gege C, Hochgürtel M, Hofmann M, Jaworski A, Jin L, Kiely A, Korniski B, Kroth H, Nix D, Nolte B, Piecha D, Powers TS, Richter F, Schneider M, Steeneck C, Sucholeiki I, Taveras A, Timmermann A, Van Veldhuizen J, Weik J, Wu X, Xia B.

Arthritis Rheum. 2009 Jul;60(7):2008-18. doi: 10.1002/art.24629.

13.

Protective effects of a cathepsin K inhibitor, SB-553484, in the canine partial medial meniscectomy model of osteoarthritis.

Connor JR, LePage C, Swift BA, Yamashita D, Bendele AM, Maul D, Kumar S.

Osteoarthritis Cartilage. 2009 Sep;17(9):1236-43. doi: 10.1016/j.joca.2009.03.015. Epub 2009 Apr 5.

14.

Prevention of cartilage degeneration in a rat model of osteoarthritis by intraarticular treatment with recombinant lubricin.

Flannery CR, Zollner R, Corcoran C, Jones AR, Root A, Rivera-Bermúdez MA, Blanchet T, Gleghorn JP, Bonassar LJ, Bendele AM, Morris EA, Glasson SS.

Arthritis Rheum. 2009 Mar;60(3):840-7. doi: 10.1002/art.24304.

15.

Exacerbation of collagen-induced arthritis by oligoclonal, IL-17-producing gamma delta T cells.

Roark CL, French JD, Taylor MA, Bendele AM, Born WK, O'Brien RL.

J Immunol. 2007 Oct 15;179(8):5576-83.

16.

Culture-independent analysis of indomethacin-induced alterations in the rat gastrointestinal microbiota.

Dalby AB, Frank DN, St Amand AL, Bendele AM, Pace NR.

Appl Environ Microbiol. 2006 Oct;72(10):6707-15.

17.

Soluble human p55 and p75 tumor necrosis factor receptors reverse spontaneous arthritis in transgenic mice expressing transmembrane tumor necrosis factor alpha.

Edwards CK 3rd, Bendele AM, Reznikov LI, Fantuzzi G, Chlipala ES, Li L, Moldawer LL, Mountz JD, Li YY, Dinarello CA.

Arthritis Rheum. 2006 Sep;54(9):2872-85.

18.

Fibroblast growth factor-18 stimulates chondrogenesis and cartilage repair in a rat model of injury-induced osteoarthritis.

Moore EE, Bendele AM, Thompson DL, Littau A, Waggie KS, Reardon B, Ellsworth JL.

Osteoarthritis Cartilage. 2005 Jul;13(7):623-31.

19.

Site-Specific Protein PEGylation: Application to Cysteine Analogs of Recombinant Human Granulocyte Colony-Stimulating Factor.

Rosendahl MS, Doherty DH, Smith DJ, Bendele AM, Cox GN.

Bioprocess Int. 2005 Apr;3(4):52-60. No abstract available.

20.

Animal models of osteoarthritis.

Bendele AM.

J Musculoskelet Neuronal Interact. 2001 Jun;1(4):363-76.

21.

Animal models of osteoarthritis in an era of molecular biology.

Bendele AM.

J Musculoskelet Neuronal Interact. 2002 Dec;2(6):501-3.

22.
23.

Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor/immunoglobulin fusion protein.

Cox GN, Smith DJ, Carlson SJ, Bendele AM, Chlipala EA, Doherty DH.

Exp Hematol. 2004 May;32(5):441-9.

PMID:
15145212
24.

Design of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) for chronic inflammatory diseases.

Edwards CK 3rd, Martin SW, Seely J, Kinstler O, Buckel S, Bendele AM, Ellen Cosenza M, Feige U, Kohno T.

Adv Drug Deliv Rev. 2003 Sep 26;55(10):1315-36. Review.

PMID:
14499710
25.

Induction of osteoarthritis in the rat by surgical tear of the meniscus: Inhibition of joint damage by a matrix metalloproteinase inhibitor.

Janusz MJ, Bendele AM, Brown KK, Taiwo YO, Hsieh L, Heitmeyer SA.

Osteoarthritis Cartilage. 2002 Oct;10(10):785-91. Erratum in: Osteoarthritis Cartilage 2002 Nov;10(1):905. Osteoarthritis Cartilage. 2003 Apr;11(4):299.

26.
27.

Treatment of rheumatoid arthritis with PEGylated recombinant human soluble tumour necrosis factor receptor type I: a clinical update.

Davis MW, Feige U, Bendele AM, Martin SW, Edwards CK 3rd.

Ann Rheum Dis. 2000 Nov;59 Suppl 1:i41-3. Review. No abstract available.

28.

Pharmacologic actions of the second generation leukotriene B4 receptor antagonist LY29311: in vivo pulmonary studies.

Silbaugh SA, Stengel PW, Cockerham SL, Froelich LL, Bendele AM, Spaethe SM, Sofia MJ, Sawyer JS, Jackson WT.

Naunyn Schmiedebergs Arch Pharmacol. 2000 Apr;361(4):397-404.

PMID:
10763854
29.

Phase I/II trial of recombinant methionyl human tumor necrosis factor binding protein PEGylated dimer in patients with active refractory rheumatoid arthritis.

Moreland LW, McCabe DP, Caldwell JR, Sack M, Weisman M, Henry G, Seely JE, Martin SW, Yee CL, Bendele AM, Frazier JL, Kohno T, Cosenza ME, Lyons SA, Dayer JM, Cohen AM, Edwards CK 3rd.

J Rheumatol. 2000 Mar;27(3):601-9.

PMID:
10743796
30.

Effects of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) alone and in combination with methotrexate in adjuvant arthritic rats.

Bendele AM, McComb J, Gould T, Frazier J, Chlipala E, Seely J, Kieft G, Edwards CK 3rd.

Clin Exp Rheumatol. 1999 Sep-Oct;17(5):553-60.

PMID:
10544838
31.

Combination benefit of PEGylated soluble tumor necrosis factor receptor type I (PEG sTNF-RI) and dexamethasone or indomethacin in adjuvant arthritic rats.

Bendele AM, McComb J, Gould T, Frazier J, Chlipala ES, Seely J, Kieft G, Wolf J, Edwards CK 3rd.

Inflamm Res. 1999 Aug;48(8):453-60.

PMID:
10493163
32.
33.

Different roles of tumour necrosis factor alpha and interleukin 1 in murine streptococcal cell wall arthritis.

Kuiper S, Joosten LA, Bendele AM, Edwards CK 3rd, Arntz OJ, Helsen MM, Van de Loo FA, Van den Berg WB.

Cytokine. 1998 Sep;10(9):690-702.

PMID:
9770330
34.

Prevention of murine collagen-induced arthritis in the knee and ipsilateral paw by local expression of human interleukin-1 receptor antagonist protein in the knee.

Bakker AC, Joosten LA, Arntz OJ, Helsen MM, Bendele AM, van de Loo FA, van den Berg WB.

Arthritis Rheum. 1997 May;40(5):893-900.

PMID:
9153551
35.

[Beneficial effects of treatment with diacerhein in guinea pigs with osteoarthritis].

Bendele AM, Bendele RA, Hulman JF, Swann BP.

Rev Prat. 1996 Mar 15;46(6 Spec No):S35-S39. French. No abstract available.

PMID:
8731730
36.

Aerosolized LTB4 produces delayed onset increases in pulmonary gas trapping.

Silbaugh SA, Stengel PW, Cockerham SL, Froelich LL, Bendele AM, Rippy MK, Baker SR, Sofia MJ, Jackson WT.

Prostaglandins Leukot Essent Fatty Acids. 1996 Feb;54(2):115-21.

PMID:
8848430
37.

Hyperoxia increases airway cell S-phase traversal in immature rats in vivo.

Hershenson MB, Kelleher MD, Naureckas ET, Abe MK, Rubinstein VJ, Zimmermann A, Bendele AM, McNulty JA, Panettieri RA, Solway J.

Am J Respir Cell Mol Biol. 1994 Sep;11(3):296-303.

PMID:
8086167
38.

Inhibition of IL-1 induced articular inflammation of rats by 4-aminothiazolidines, LY 221068 and LY 269415.

Chandrasekhar S, Panetta JA, Bendele AM.

Agents Actions. 1994 Aug;42(1-2):67-70.

PMID:
7847188
39.

Chronic toxicity, metabolism, and pharmacokinetics of the 5-HT3 receptor antagonist zatosetron (LY277359) in Fischer 344 rats.

Bendele AM, Buenger DA, McGrath JP, Schmalz CA, Hanasono GK.

Fundam Appl Toxicol. 1994 May;22(4):494-504.

PMID:
8056197
40.

Effect of dexamethasone on A23187-induced airway responses in the guinea pig.

Stengel PW, Bendele AM, Cockerham SL, Silbaugh SA.

Eur J Pharmacol. 1994 Mar 3;253(3):253-9.

PMID:
7515351
41.

Effect of weight manipulation on bone loss due to ovariectomy and the protective effects of estrogen in the rat.

Roudebush RE, Magee DE, Benslay DN, Bendele AM, Bryant HU.

Calcif Tissue Int. 1993 Jul;53(1):61-4.

PMID:
8348385
42.

Hepatocellular proliferation in ibuprofen-treated mice.

Bendele AM, Hulman JF, White S, Brodhecker C, Bendele RA.

Toxicol Pathol. 1993;21(1):15-20.

PMID:
8378703
43.

Inhaled A23187 produces a preferential sensitization to substance P.

Stengel PW, Bendele AM, Cockerham SL, Silbaugh SA.

Am Rev Respir Dis. 1993 Jan;147(1):196-201.

PMID:
7678372
44.

Sulfuric acid induces airway hyperresponsiveness to substance P in the guinea pig.

Stengel PW, Bendele AM, Cockerham SL, Silbaugh SA.

Agents Actions. 1993;39 Spec No:C128-31.

PMID:
7505997
45.

Correlation of anti-inflammatory activity with peak tissue rather than peak plasma levels of BF389.

Bendele AM, Ruterbories KJ, Spaethe SM, Benslay DN, Lindstrom TD, Lee SJ, Naismith RW.

J Pharmacol Exp Ther. 1992 Mar;260(3):1194-8.

PMID:
1545387
47.
48.

Anti-inflammatory activity of BF389, a Di-T-butylphenol, in animal models of arthritis.

Bendele AM, Benslay DN, Hom JT, Spaethe SM, Ruterbories KJ, Lindstrom TD, Lee SJ, Naismith RW.

J Pharmacol Exp Ther. 1992 Jan;260(1):300-5.

PMID:
1309875
49.

Anti-inflammatory activity of pergolide, a dopamine receptor agonist.

Bendele AM, Spaethe SM, Benslay DN, Bryant HU.

J Pharmacol Exp Ther. 1991 Oct;259(1):169-75.

PMID:
1681083
50.

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