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Items: 1 to 50 of 112

1.

β-TrCP upregulates HIF-1 in prostate cancer cells.

Cohen M, Amir S, Golan M, Ben-Neriah Y, Mabjeesh NJ.

Prostate. 2019 Mar;79(4):403-413. doi: 10.1002/pros.23746. Epub 2018 Nov 28.

PMID:
30488478
2.

Small Molecules Co-targeting CKIα and the Transcriptional Kinases CDK7/9 Control AML in Preclinical Models.

Minzel W, Venkatachalam A, Fink A, Hung E, Brachya G, Burstain I, Shaham M, Rivlin A, Omer I, Zinger A, Elias S, Winter E, Erdman PE, Sullivan RW, Fung L, Mercurio F, Li D, Vacca J, Kaushansky N, Shlush L, Oren M, Levine R, Pikarsky E, Snir-Alkalay I, Ben-Neriah Y.

Cell. 2018 Sep 20;175(1):171-185.e25. doi: 10.1016/j.cell.2018.07.045. Epub 2018 Aug 23.

PMID:
30146162
3.

Casein kinase 1-epsilon or 1-delta required for Wnt-mediated intestinal stem cell maintenance.

Morgenstern Y, Das Adhikari U, Ayyash M, Elyada E, Tóth B, Moor A, Itzkovitz S, Ben-Neriah Y.

EMBO J. 2017 Oct 16;36(20):3046-3061. doi: 10.15252/embj.201696253. Epub 2017 Sep 28.

4.

CK1α ablation in keratinocytes induces p53-dependent, sunburn-protective skin hyperpigmentation.

Chang CH, Kuo CJ, Ito T, Su YY, Jiang ST, Chiu MH, Lin YH, Nist A, Mernberger M, Stiewe T, Ito S, Wakamatsu K, Hsueh YA, Shieh SY, Snir-Alkalay I, Ben-Neriah Y.

Proc Natl Acad Sci U S A. 2017 Sep 19;114(38):E8035-E8044. doi: 10.1073/pnas.1702763114. Epub 2017 Sep 6.

5.

Cancer Cell-Autonomous Parainflammation Mimics Immune Cell Infiltration.

Lasry A, Aran D, Butte AJ, Ben-Neriah Y.

Cancer Res. 2017 Jul 15;77(14):3740-3744. doi: 10.1158/0008-5472.CAN-16-3383. Epub 2017 Jun 30.

6.

p53 elevation in human cells halt SV40 infection by inhibiting T-ag expression.

Drayman N, Ben-Nun-Shaul O, Butin-Israeli V, Srivastava R, Rubinstein AM, Mock CS, Elyada E, Ben-Neriah Y, Lahav G, Oppenheim A.

Oncotarget. 2016 Aug 16;7(33):52643-52660. doi: 10.18632/oncotarget.10769.

7.

Widespread parainflammation in human cancer.

Aran D, Lasry A, Zinger A, Biton M, Pikarsky E, Hellman A, Butte AJ, Ben-Neriah Y.

Genome Biol. 2016 Jul 8;17(1):145. doi: 10.1186/s13059-016-0995-z.

8.

Inflammatory networks underlying colorectal cancer.

Lasry A, Zinger A, Ben-Neriah Y.

Nat Immunol. 2016 Mar;17(3):230-40. doi: 10.1038/ni.3384. Review.

PMID:
26882261
9.

Type I Interferons Control Proliferation and Function of the Intestinal Epithelium.

Katlinskaya YV, Katlinski KV, Lasri A, Li N, Beiting DP, Durham AC, Yang T, Pikarsky E, Lengner CJ, Johnson FB, Ben-Neriah Y, Fuchs SY.

Mol Cell Biol. 2016 Jan 25;36(7):1124-35. doi: 10.1128/MCB.00988-15.

10.

Ectopic lymphoid structures function as microniches for tumor progenitor cells in hepatocellular carcinoma.

Finkin S, Yuan D, Stein I, Taniguchi K, Weber A, Unger K, Browning JL, Goossens N, Nakagawa S, Gunasekaran G, Schwartz ME, Kobayashi M, Kumada H, Berger M, Pappo O, Rajewsky K, Hoshida Y, Karin M, Heikenwalder M, Ben-Neriah Y, Pikarsky E.

Nat Immunol. 2015 Dec;16(12):1235-44. doi: 10.1038/ni.3290. Epub 2015 Oct 26.

11.

One more wheel for a processing machine.

Ben-Neriah Y.

Cell Death Differ. 2015 Aug;22(8):1235-6. doi: 10.1038/cdd.2015.71. No abstract available.

12.

A Systematic Approach to Defining the microRNA Landscape in Metastasis.

Mudduluru G, Abba M, Batliner J, Patil N, Scharp M, Lunavat TR, Leupold JH, Oleksiuk O, Juraeva D, Thiele W, Rothley M, Benner A, Ben-Neriah Y, Sleeman J, Allgayer H.

Cancer Res. 2015 Aug 1;75(15):3010-9. doi: 10.1158/0008-5472.CAN-15-0997. Epub 2015 Jun 11.

13.

Senescence-associated inflammatory responses: aging and cancer perspectives.

Lasry A, Ben-Neriah Y.

Trends Immunol. 2015 Apr;36(4):217-28. doi: 10.1016/j.it.2015.02.009. Epub 2015 Mar 21. Review.

PMID:
25801910
14.

[Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance].

Wiener Z, Högström J, Hyvönen V, Band A, Kallio P, Holopainen T, Dufva O, Haglund C, Kruuna O, Oliver G, Ben-Neriah Y, Alitalo K.

Duodecim. 2014;130(21):2208. Review. Finnish. No abstract available.

PMID:
25582015
15.

Animal model studies indicate a candidate biomarker for sorafenib treatment of hepatocellular carcinoma.

Horwitz E, Stein I, Ben-Neriah Y, Pikarsky E.

Mol Cell Oncol. 2014 Oct 30;2(1):e968028. doi: 10.4161/23723548.2014.968028. eCollection 2015 Jan-Mar.

16.

Acquisition of an immunosuppressive protumorigenic macrophage phenotype depending on c-Jun phosphorylation.

Hefetz-Sela S, Stein I, Klieger Y, Porat R, Sade-Feldman M, Zreik F, Nagler A, Pappo O, Quagliata L, Dazert E, Eferl R, Terracciano L, Wagner EF, Ben-Neriah Y, Baniyash M, Pikarsky E.

Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):17582-7. doi: 10.1073/pnas.1409700111. Epub 2014 Nov 24.

17.

Prox1 promotes expansion of the colorectal cancer stem cell population to fuel tumor growth and ischemia resistance.

Wiener Z, Högström J, Hyvönen V, Band AM, Kallio P, Holopainen T, Dufva O, Haglund C, Kruuna O, Oliver G, Ben-Neriah Y, Alitalo K.

Cell Rep. 2014 Sep 25;8(6):1943-1956. doi: 10.1016/j.celrep.2014.08.034. Epub 2014 Sep 18.

18.

Oncogenic mutations in intestinal adenomas regulate Bim-mediated apoptosis induced by TGF-β.

Wiener Z, Band AM, Kallio P, Högström J, Hyvönen V, Kaijalainen S, Ritvos O, Haglund C, Kruuna O, Robine S, Louvard D, Ben-Neriah Y, Alitalo K.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2229-36. doi: 10.1073/pnas.1406444111. Epub 2014 May 13.

19.

Human and mouse VEGFA-amplified hepatocellular carcinomas are highly sensitive to sorafenib treatment.

Horwitz E, Stein I, Andreozzi M, Nemeth J, Shoham A, Pappo O, Schweitzer N, Tornillo L, Kanarek N, Quagliata L, Zreik F, Porat RM, Finkelstein R, Reuter H, Koschny R, Ganten T, Mogler C, Shibolet O, Hess J, Breuhahn K, Grunewald M, Schirmacher P, Vogel A, Terracciano L, Angel P, Ben-Neriah Y, Pikarsky E.

Cancer Discov. 2014 Jun;4(6):730-43. doi: 10.1158/2159-8290.CD-13-0782. Epub 2014 Mar 31.

20.

Critical role for IL-1β in DNA damage-induced mucositis.

Kanarek N, Grivennikov SI, Leshets M, Lasry A, Alkalay I, Horwitz E, Shaul YD, Stachler M, Voronov E, Apte RN, Pagano M, Pikarsky E, Karin M, Ghosh S, Ben-Neriah Y.

Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):E702-11. doi: 10.1073/pnas.1322691111. Epub 2014 Jan 27.

21.

A senescence-inflammatory switch from cancer-inhibitory to cancer-promoting mechanism.

Pribluda A, Elyada E, Wiener Z, Hamza H, Goldstein RE, Biton M, Burstain I, Morgenstern Y, Brachya G, Billauer H, Biton S, Snir-Alkalay I, Vucic D, Schlereth K, Mernberger M, Stiewe T, Oren M, Alitalo K, Pikarsky E, Ben-Neriah Y.

Cancer Cell. 2013 Aug 12;24(2):242-56. doi: 10.1016/j.ccr.2013.06.005. Epub 2013 Jul 25. Erratum in: Cancer Cell. 2015 Jun 8;27(6):877-8.

22.

Genome-wide analysis of androgen receptor targets reveals COUP-TF1 as a novel player in human prostate cancer.

Perets R, Kaplan T, Stein I, Hidas G, Tayeb S, Avraham E, Ben-Neriah Y, Simon I, Pikarsky E.

PLoS One. 2012;7(10):e46467. doi: 10.1371/journal.pone.0046467. Epub 2012 Oct 4.

23.

Regulation of NF-κB by ubiquitination and degradation of the IκBs.

Kanarek N, Ben-Neriah Y.

Immunol Rev. 2012 Mar;246(1):77-94. doi: 10.1111/j.1600-065X.2012.01098.x. Review.

PMID:
22435548
24.

mTOR generates an auto-amplification loop by triggering the βTrCP- and CK1α-dependent degradation of DEPTOR.

Duan S, Skaar JR, Kuchay S, Toschi A, Kanarek N, Ben-Neriah Y, Pagano M.

Mol Cell. 2011 Oct 21;44(2):317-24. doi: 10.1016/j.molcel.2011.09.005.

25.

Inflammation meets cancer, with NF-κB as the matchmaker.

Ben-Neriah Y, Karin M.

Nat Immunol. 2011 Jul 19;12(8):715-23. doi: 10.1038/ni.2060. Review.

PMID:
21772280
26.

CKIα ablation highlights a critical role for p53 in invasiveness control.

Elyada E, Pribluda A, Goldstein RE, Morgenstern Y, Brachya G, Cojocaru G, Snir-Alkalay I, Burstain I, Haffner-Krausz R, Jung S, Wiener Z, Alitalo K, Oren M, Pikarsky E, Ben-Neriah Y.

Nature. 2011 Feb 17;470(7334):409-13. doi: 10.1038/nature09673.

PMID:
21331045
27.

Epithelial microRNAs regulate gut mucosal immunity via epithelium-T cell crosstalk.

Biton M, Levin A, Slyper M, Alkalay I, Horwitz E, Mor H, Kredo-Russo S, Avnit-Sagi T, Cojocaru G, Zreik F, Bentwich Z, Poy MN, Artis D, Walker MD, Hornstein E, Pikarsky E, Ben-Neriah Y.

Nat Immunol. 2011 Mar;12(3):239-46. doi: 10.1038/ni.1994. Epub 2011 Jan 30.

PMID:
21278735
28.

Metalloprotease type III effectors that specifically cleave JNK and NF-κB.

Baruch K, Gur-Arie L, Nadler C, Koby S, Yerushalmi G, Ben-Neriah Y, Yogev O, Shaulian E, Guttman C, Zarivach R, Rosenshine I.

EMBO J. 2011 Jan 5;30(1):221-31. doi: 10.1038/emboj.2010.297. Epub 2010 Nov 26.

29.

Spermatogenesis rescue in a mouse deficient for the ubiquitin ligase SCF{beta}-TrCP by single substrate depletion.

Kanarek N, Horwitz E, Mayan I, Leshets M, Cojocaru G, Davis M, Tsuberi BZ, Pikarsky E, Pagano M, Ben-Neriah Y.

Genes Dev. 2010 Mar 1;24(5):470-7. doi: 10.1101/gad.551610.

30.

Ubiquitination and degradation of the inhibitors of NF-kappaB.

Kanarek N, London N, Schueler-Furman O, Ben-Neriah Y.

Cold Spring Harb Perspect Biol. 2010 Feb;2(2):a000166. doi: 10.1101/cshperspect.a000166. Review.

31.

beta-TrCP inhibition reduces prostate cancer cell growth via upregulation of the aryl hydrocarbon receptor.

Gluschnaider U, Hidas G, Cojocaru G, Yutkin V, Ben-Neriah Y, Pikarsky E.

PLoS One. 2010 Feb 5;5(2):e9060. doi: 10.1371/journal.pone.0009060.

32.

The type III secretion effector NleE inhibits NF-kappaB activation.

Nadler C, Baruch K, Kobi S, Mills E, Haviv G, Farago M, Alkalay I, Bartfeld S, Meyer TF, Ben-Neriah Y, Rosenshine I.

PLoS Pathog. 2010 Jan 29;6(1):e1000743. doi: 10.1371/journal.ppat.1000743.

33.

iC3b-opsonized apoptotic cells mediate a distinct anti-inflammatory response and transcriptional NF-kappaB-dependent blockade.

Amarilyo G, Verbovetski I, Atallah M, Grau A, Wiser G, Gil O, Ben-Neriah Y, Mevorach D.

Eur J Immunol. 2010 Mar;40(3):699-709. doi: 10.1002/eji.200838951.

34.

S100A8 and S100A9 are novel nuclear factor kappa B target genes during malignant progression of murine and human liver carcinogenesis.

Németh J, Stein I, Haag D, Riehl A, Longerich T, Horwitz E, Breuhahn K, Gebhardt C, Schirmacher P, Hahn M, Ben-Neriah Y, Pikarsky E, Angel P, Hess J.

Hepatology. 2009 Oct;50(4):1251-62. doi: 10.1002/hep.23099.

PMID:
19670424
35.

Design and synthesis of backbone cyclic phosphopeptides: the IkappaB model.

Qvit N, Hatzubai A, Shalev DE, Ben-Neriah Y, Gilon C.

Adv Exp Med Biol. 2009;611:139-40. No abstract available.

PMID:
19400129
36.

Design and synthesis of backbone cyclic phosphorylated peptides: The IkappaB model.

Qvit N, Hatzubai A, Shalev DE, Friedler A, Ben-Neriah Y, Gilon C.

Biopolymers. 2009 Feb;91(2):157-68. doi: 10.1002/bip.21098.

PMID:
19025995
37.

Contradictory functions of NF-kappaB in liver physiology and cancer.

Vainer GW, Pikarsky E, Ben-Neriah Y.

Cancer Lett. 2008 Aug 28;267(2):182-8. doi: 10.1016/j.canlet.2008.03.016. Epub 2008 May 13. Review.

PMID:
18479806
38.

Incensole acetate: a novel neuroprotective agent isolated from Boswellia carterii.

Moussaieff A, Shein NA, Tsenter J, Grigoriadis S, Simeonidou C, Alexandrovich AG, Trembovler V, Ben-Neriah Y, Schmitz ML, Fiebich BL, Munoz E, Mechoulam R, Shohami E.

J Cereb Blood Flow Metab. 2008 Jul;28(7):1341-52. doi: 10.1038/jcbfm.2008.28. Epub 2008 Apr 16.

PMID:
18414499
39.

Incensole acetate, a novel anti-inflammatory compound isolated from Boswellia resin, inhibits nuclear factor-kappa B activation.

Moussaieff A, Shohami E, Kashman Y, Fride E, Schmitz ML, Renner F, Fiebich BL, Munoz E, Ben-Neriah Y, Mechoulam R.

Mol Pharmacol. 2007 Dec;72(6):1657-64. Epub 2007 Sep 25.

PMID:
17895408
40.

Enhanced heat shock protein 70 expression alters proteasomal degradation of IkappaB kinase in experimental acute respiratory distress syndrome.

Weiss YG, Bromberg Z, Raj N, Raphael J, Goloubinoff P, Ben-Neriah Y, Deutschman CS.

Crit Care Med. 2007 Sep;35(9):2128-38.

PMID:
17855826
41.

Epithelial NF-kappaB maintains host gut microflora homeostasis.

Ben-Neriah Y, Schmidt-Supprian M.

Nat Immunol. 2007 May;8(5):479-81. No abstract available.

PMID:
17440457
42.

Maintenance of colonic homeostasis by distinctive apical TLR9 signalling in intestinal epithelial cells.

Lee J, Mo JH, Katakura K, Alkalay I, Rucker AN, Liu YT, Lee HK, Shen C, Cojocaru G, Shenouda S, Kagnoff M, Eckmann L, Ben-Neriah Y, Raz E.

Nat Cell Biol. 2006 Dec;8(12):1327-36. Epub 2006 Nov 26.

PMID:
17128265
43.

Conditional and specific NF-kappaB blockade protects pancreatic beta cells from diabetogenic agents.

Eldor R, Yeffet A, Baum K, Doviner V, Amar D, Ben-Neriah Y, Christofori G, Peled A, Carel JC, Boitard C, Klein T, Serup P, Eizirik DL, Melloul D.

Proc Natl Acad Sci U S A. 2006 Mar 28;103(13):5072-7. Epub 2006 Mar 21.

44.

NF-kappaB inhibition: a double-edged sword in cancer?

Pikarsky E, Ben-Neriah Y.

Eur J Cancer. 2006 Apr;42(6):779-84. Epub 2006 Mar 10. Review.

PMID:
16530406
45.

Inflammation and cancer: is the link as simple as we think?

Nickoloff BJ, Ben-Neriah Y, Pikarsky E.

J Invest Dermatol. 2005 Jun;124(6):x-xiv. Review. No abstract available.

46.

Inhibition of NF-kappaB activation and expression of inflammatory mediators by polyacetylene spiroketals from Plagius flosculosus.

Calzado MA, Lüdi KS, Fiebich B, Ben-Neriah Y, Bacher S, Munoz E, Ballero M, Prosperini S, Appendino G, Schmitz ML.

Biochim Biophys Acta. 2005 Jun 30;1729(2):88-93.

PMID:
15949852
47.

NFkappaB: Bench to Bedside - Keystone Symposium. 25 February - 3 March 2002, Keystone, CO, USA.

Amit S, Ben-Neriah Y.

IDrugs. 2002 Apr;5(4):331-5. No abstract available.

PMID:
15565513
48.

NF-kappaB functions as a tumour promoter in inflammation-associated cancer.

Pikarsky E, Porat RM, Stein I, Abramovitch R, Amit S, Kasem S, Gutkovich-Pyest E, Urieli-Shoval S, Galun E, Ben-Neriah Y.

Nature. 2004 Sep 23;431(7007):461-6. Epub 2004 Aug 25.

49.

Of mice and men.

Ben-Neriah Y, Schmitz ML.

EMBO Rep. 2004 Jul;5(7):668-73. Epub 2004 Jun 25. No abstract available.

50.

Behind the scenes of anergy: a tale of three E3s.

Davis M, Ben-Neriah Y.

Nat Immunol. 2004 Mar;5(3):238-40. No abstract available.

PMID:
14985708

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