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Items: 23

1.

In Vivo Delivery of a DNA-Encoded Monoclonal Antibody Protects Non-human Primates against Zika Virus.

Esquivel RN, Patel A, Kudchodkar SB, Park DH, Stettler K, Beltramello M, Allen JW, Mendoza J, Ramos S, Choi H, Borole P, Asija K, Bah M, Shaheen S, Chen J, Yan J, Durham AC, Smith TRF, Broderick K, Guibinga G, Muthumani K, Corti D, Humeau L, Weiner DB.

Mol Ther. 2019 May 8;27(5):974-985. doi: 10.1016/j.ymthe.2019.03.005. Epub 2019 Apr 5.

2.

Structure-based design of a quadrivalent fusion glycoprotein vaccine for human parainfluenza virus types 1-4.

Stewart-Jones GBE, Chuang GY, Xu K, Zhou T, Acharya P, Tsybovsky Y, Ou L, Zhang B, Fernandez-Rodriguez B, Gilardi V, Silacci-Fregni C, Beltramello M, Baxa U, Druz A, Kong WP, Thomas PV, Yang Y, Foulds KE, Todd JP, Wei H, Salazar AM, Scorpio DG, Carragher B, Potter CS, Corti D, Mascola JR, Lanzavecchia A, Kwong PD.

Proc Natl Acad Sci U S A. 2018 Nov 27;115(48):12265-12270. doi: 10.1073/pnas.1811980115. Epub 2018 Nov 12.

3.

Conformational Occlusion of Blockade Antibody Epitopes, a Novel Mechanism of GII.4 Human Norovirus Immune Evasion.

Lindesmith LC, Mallory ML, Debbink K, Donaldson EF, Brewer-Jensen PD, Swann EW, Sheahan TP, Graham RL, Beltramello M, Corti D, Lanzavecchia A, Baric RS.

mSphere. 2018 Feb 7;3(1). pii: e00518-17. doi: 10.1128/mSphere.00518-17. eCollection 2018 Jan-Feb.

4.

Immune stealth-driven O2 serotype prevalence and potential for therapeutic antibodies against multidrug resistant Klebsiella pneumoniae.

Pennini ME, De Marco A, Pelletier M, Bonnell J, Cvitkovic R, Beltramello M, Cameroni E, Bianchi S, Zatta F, Zhao W, Xiao X, Camara MM, DiGiandomenico A, Semenova E, Lanzavecchia A, Warrener P, Suzich J, Wang Q, Corti D, Stover CK.

Nat Commun. 2017 Dec 8;8(1):1991. doi: 10.1038/s41467-017-02223-7.

5.

A Human Bi-specific Antibody against Zika Virus with High Therapeutic Potential.

Wang J, Bardelli M, Espinosa DA, Pedotti M, Ng TS, Bianchi S, Simonelli L, Lim EXY, Foglierini M, Zatta F, Jaconi S, Beltramello M, Cameroni E, Fibriansah G, Shi J, Barca T, Pagani I, Rubio A, Broccoli V, Vicenzi E, Graham V, Pullan S, Dowall S, Hewson R, Jurt S, Zerbe O, Stettler K, Lanzavecchia A, Sallusto F, Cavalli A, Harris E, Lok SM, Varani L, Corti D.

Cell. 2017 Sep 21;171(1):229-241.e15. doi: 10.1016/j.cell.2017.09.002.

6.

Circadian clock as possible protective mechanism to pollution induced keratinocytes damage.

Benedusi M, Frigato E, Beltramello M, Bertolucci C, Valacchi G.

Mech Ageing Dev. 2018 Jun;172:13-20. doi: 10.1016/j.mad.2017.08.017. Epub 2017 Aug 30.

PMID:
28860071
7.

Specificity, cross-reactivity, and function of antibodies elicited by Zika virus infection.

Stettler K, Beltramello M, Espinosa DA, Graham V, Cassotta A, Bianchi S, Vanzetta F, Minola A, Jaconi S, Mele F, Foglierini M, Pedotti M, Simonelli L, Dowall S, Atkinson B, Percivalle E, Simmons CP, Varani L, Blum J, Baldanti F, Cameroni E, Hewson R, Harris E, Lanzavecchia A, Sallusto F, Corti D.

Science. 2016 Aug 19;353(6301):823-6. doi: 10.1126/science.aaf8505. Epub 2016 Jul 14.

8.

Serum Immunoglobulin A Cross-Strain Blockade of Human Noroviruses.

Lindesmith LC, Beltramello M, Swanstrom J, Jones TA, Corti D, Lanzavecchia A, Baric RS.

Open Forum Infect Dis. 2015 Jul 1;2(3):ofv084. doi: 10.1093/ofid/ofv084. eCollection 2015 Sep.

9.

Particle conformation regulates antibody access to a conserved GII.4 norovirus blockade epitope.

Lindesmith LC, Donaldson EF, Beltramello M, Pintus S, Corti D, Swanstrom J, Debbink K, Jones TA, Lanzavecchia A, Baric RS.

J Virol. 2014 Aug;88(16):8826-42. doi: 10.1128/JVI.01192-14. Epub 2014 May 28.

10.

Within-host evolution results in antigenically distinct GII.4 noroviruses.

Debbink K, Lindesmith LC, Ferris MT, Swanstrom J, Beltramello M, Corti D, Lanzavecchia A, Baric RS.

J Virol. 2014 Jul;88(13):7244-55. doi: 10.1128/JVI.00203-14. Epub 2014 Mar 19.

11.

Emergence of new pandemic GII.4 Sydney norovirus strain correlates with escape from herd immunity.

Debbink K, Lindesmith LC, Donaldson EF, Costantini V, Beltramello M, Corti D, Swanstrom J, Lanzavecchia A, Vinjé J, Baric RS.

J Infect Dis. 2013 Dec 1;208(11):1877-87. doi: 10.1093/infdis/jit370. Epub 2013 Aug 1.

12.

Therapeutic efficacy of antibodies lacking Fcγ receptor binding against lethal dengue virus infection is due to neutralizing potency and blocking of enhancing antibodies [corrected].

Williams KL, Sukupolvi-Petty S, Beltramello M, Johnson S, Sallusto F, Lanzavecchia A, Diamond MS, Harris E.

PLoS Pathog. 2013 Feb;9(2):e1003157. doi: 10.1371/journal.ppat.1003157. Epub 2013 Feb 14. Erratum in: PLoS Pathog. 2013 Mar;9(3). doi:10.1371/annotation/e08f911a-15ec-46d0-bede-83fdf3af1801.

13.

Rational engineering of a human anti-dengue antibody through experimentally validated computational docking.

Simonelli L, Pedotti M, Beltramello M, Livoti E, Calzolai L, Sallusto F, Lanzavecchia A, Varani L.

PLoS One. 2013;8(2):e55561. doi: 10.1371/journal.pone.0055561. Epub 2013 Feb 6.

14.

Immunogenetic mechanisms driving norovirus GII.4 antigenic variation.

Lindesmith LC, Beltramello M, Donaldson EF, Corti D, Swanstrom J, Debbink K, Lanzavecchia A, Baric RS.

PLoS Pathog. 2012;8(5):e1002705. doi: 10.1371/journal.ppat.1002705. Epub 2012 May 17.

15.

In-depth analysis of the antibody response of individuals exposed to primary dengue virus infection.

de Alwis R, Beltramello M, Messer WB, Sukupolvi-Petty S, Wahala WM, Kraus A, Olivarez NP, Pham Q, Brien JD, Tsai WY, Wang WK, Halstead S, Kliks S, Diamond MS, Baric R, Lanzavecchia A, Sallusto F, de Silva AM.

PLoS Negl Trop Dis. 2011 Jun;5(6):e1188. doi: 10.1371/journal.pntd.0001188. Epub 2011 Jun 21. Erratum in: PLoS Negl Trop Dis. 2011 Aug;5(8). doi: 10.1371/annotation/f585335f-ff77-40ae-a8b6-ad6019af31aa. Brian, James [corrected to Brien, James D].

16.

Human antibodies against dengue enhance dengue viral infectivity without suppressing type I interferon secretion in primary human monocytes.

Kou Z, Lim JY, Beltramello M, Quinn M, Chen H, Liu S, Martinez-Sobrido L, Diamond MS, Schlesinger JJ, de Silva A, Sallusto F, Jin X.

Virology. 2011 Feb 5;410(1):240-7. doi: 10.1016/j.virol.2010.11.007. Epub 2010 Dec 4. Erratum in: Virology. 2011 May 10;413(2):320. Liu, Shengyo-ng [corrected to Liu, Shengyong]; Martnez-Sobrido, Luis [corrected to Martinez-Sobrido, Luis].

17.

The human immune response to Dengue virus is dominated by highly cross-reactive antibodies endowed with neutralizing and enhancing activity.

Beltramello M, Williams KL, Simmons CP, Macagno A, Simonelli L, Quyen NT, Sukupolvi-Petty S, Navarro-Sanchez E, Young PR, de Silva AM, Rey FA, Varani L, Whitehead SS, Diamond MS, Harris E, Lanzavecchia A, Sallusto F.

Cell Host Microbe. 2010 Sep 16;8(3):271-83. doi: 10.1016/j.chom.2010.08.007.

18.

Rapid structural characterization of human antibody-antigen complexes through experimentally validated computational docking.

Simonelli L, Beltramello M, Yudina Z, Macagno A, Calzolai L, Varani L.

J Mol Biol. 2010 Mar 12;396(5):1491-507. doi: 10.1016/j.jmb.2009.12.053. Epub 2010 Jan 4.

PMID:
20053355
19.

Unitary permeability of gap junction channels to second messengers measured by FRET microscopy.

Hernandez VH, Bortolozzi M, Pertegato V, Beltramello M, Giarin M, Zaccolo M, Pantano S, Mammano F.

Nat Methods. 2007 Apr;4(4):353-8. Epub 2007 Mar 11.

PMID:
17351620
20.

Pathogenetic role of the deafness-related M34T mutation of Cx26.

Bicego M, Beltramello M, Melchionda S, Carella M, Piazza V, Zelante L, Bukauskas FF, Arslan E, Cama E, Pantano S, Bruzzone R, D'Andrea P, Mammano F.

Hum Mol Genet. 2006 Sep 1;15(17):2569-87. Epub 2006 Jul 18.

21.

Functional analysis of R75Q mutation in the gene coding for Connexin 26 identified in a family with nonsyndromic hearing loss.

Piazza V, Beltramello M, Menniti M, Colao E, Malatesta P, Argento R, Chiarella G, Gallo LV, Catalano M, Perrotti N, Mammano F, Cassandro E.

Clin Genet. 2005 Aug;68(2):161-6.

PMID:
15996214
22.

Impaired permeability to Ins(1,4,5)P3 in a mutant connexin underlies recessive hereditary deafness.

Beltramello M, Piazza V, Bukauskas FF, Pozzan T, Mammano F.

Nat Cell Biol. 2005 Jan;7(1):63-9. Epub 2004 Dec 12.

PMID:
15592461
23.

Permeability and gating properties of human connexins 26 and 30 expressed in HeLa cells.

Beltramello M, Bicego M, Piazza V, Ciubotaru CD, Mammano F, D'Andrea P.

Biochem Biophys Res Commun. 2003 Jun 13;305(4):1024-33.

PMID:
12767933

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