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Items: 36

1.

Different monocyte phenotypes result in proresolving macrophages in conjugated linoleic acid-induced attenuated progression and regression of atherosclerosis.

Bruen R, Curley S, Kajani S, Lynch G, O'Reilly ME, Dillon ET, Fitzsimons S, Mthunzi L, McGillicuddy FC, Belton O.

FASEB J. 2019 Jul 5:fj201900922R. doi: 10.1096/fj.201900922R. [Epub ahead of print]

PMID:
31284764
2.

Liraglutide attenuates pre-established atherosclerosis in apolipoprotein E deficient mice via regulation of immune cell phenotypes and pro-inflammatory mediators.

Bruen R, Curley S, Kajani S, Lynch G, O'Reilly ME, Dillon ET, Brennan EP, Barry M, Sheehan S, McGillicuddy F, Belton O.

J Pharmacol Exp Ther. 2019 Jul 3. pii: jpet.119.258343. doi: 10.1124/jpet.119.258343. [Epub ahead of print]

3.

miR-155 in the Resolution of Atherosclerosis.

Bruen R, Fitzsimons S, Belton O.

Front Pharmacol. 2019 May 14;10:463. doi: 10.3389/fphar.2019.00463. eCollection 2019. Review.

4.

ApoE elevation is associated with the persistence of psychotic experiences from age 12 to age 18: Evidence from the ALSPAC birth cohort.

Sabherwal S, Föcking M, English JA, Fitzsimons S, Hryniewiecka M, Wynne K, Scaife C, Healy C, Cannon M, Belton O, Zammit S, Cagney G, Cotter DR.

Schizophr Res. 2019 Jul;209:141-147. doi: 10.1016/j.schres.2019.05.002. Epub 2019 May 10.

PMID:
31080155
5.

Lipoxins Protect Against Inflammation in Diabetes-Associated Atherosclerosis.

Brennan EP, Mohan M, McClelland A, de Gaetano M, Tikellis C, Marai M, Crean D, Dai A, Beuscart O, Derouiche S, Gray SP, Pickering R, Tan SM, Godson-Treacy M, Sheehan S, Dowdall JF, Barry M, Belton O, Ali-Shah ST, Guiry PJ, Jandeleit-Dahm K, Cooper ME, Godson C, Kantharidis P.

Diabetes. 2018 Dec;67(12):2657-2667. doi: 10.2337/db17-1317. Epub 2018 Sep 13.

6.

Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis.

Bruen R, Curley S, Kajani S, Crean D, O'Reilly ME, Lucitt MB, Godson CG, McGillicuddy FC, Belton O.

Cardiovasc Diabetol. 2017 Nov 6;16(1):143. doi: 10.1186/s12933-017-0626-3.

7.

Protective Effect of let-7 miRNA Family in Regulating Inflammation in Diabetes-Associated Atherosclerosis.

Brennan E, Wang B, McClelland A, Mohan M, Marai M, Beuscart O, Derouiche S, Gray S, Pickering R, Tikellis C, de Gaetano M, Barry M, Belton O, Ali-Shah ST, Guiry P, Jandeleit-Dahm KAM, Cooper ME, Godson C, Kantharidis P.

Diabetes. 2017 Aug;66(8):2266-2277. doi: 10.2337/db16-1405. Epub 2017 May 9.

8.

NR4A Receptors Differentially Regulate NF-κB Signaling in Myeloid Cells.

McEvoy C, de Gaetano M, Giffney HE, Bahar B, Cummins EP, Brennan EP, Barry M, Belton O, Godson CG, Murphy EP, Crean D.

Front Immunol. 2017 Jan 23;8:7. doi: 10.3389/fimmu.2017.00007. eCollection 2017.

9.

M1- and M2-Type Macrophage Responses Are Predictive of Adverse Outcomes in Human Atherosclerosis.

de Gaetano M, Crean D, Barry M, Belton O.

Front Immunol. 2016 Jul 19;7:275. doi: 10.3389/fimmu.2016.00275. eCollection 2016.

10.

Milk-derived bioactive peptides and their health promoting effects: a potential role in atherosclerosis.

Marcone S, Belton O, Fitzgerald DJ.

Br J Clin Pharmacol. 2017 Jan;83(1):152-162. doi: 10.1111/bcp.13002. Epub 2016 Jun 17. Review.

11.

Atheroprotective effects of conjugated linoleic acid.

Bruen R, Fitzsimons S, Belton O.

Br J Clin Pharmacol. 2017 Jan;83(1):46-53. doi: 10.1111/bcp.12948. Epub 2016 May 7. Review.

12.

Dysregulated post-transcriptional control of COX-2 gene expression in gestational diabetic endothelial cells.

Di Francesco L, Dovizio M, Trenti A, Marcantoni E, Moore A, O'Gaora P, McCarthy C, Tacconelli S, Bruno A, Alberti S, Gizzo S, Nardelli GB, Orso G, Belton O, Trevisi L, Dixon DA, Patrignani P.

Br J Pharmacol. 2015 Sep;172(18):4575-4587. doi: 10.1111/bph.13241. Epub 2015 Aug 3.

13.

Dysregulation of gene expression in human fetal endothelial cells from gestational diabetes in response to TGF-β1.

Marcantoni E, Dovizio M, O'Gaora P, Di Francesco L, Bendaya I, Schiavone S, Trenti A, Guillem-Llobat P, Zambon A, Nardelli GB, Trevisi L, Patrignani P, Belton O.

Prostaglandins Other Lipid Mediat. 2015 Jul;120:103-14. doi: 10.1016/j.prostaglandins.2015.03.004. Epub 2015 Mar 26.

PMID:
25819880
14.

Conjugated linoleic acid induces an atheroprotective macrophage MΦ2 phenotype and limits foam cell formation.

de Gaetano M, Alghamdi K, Marcone S, Belton O.

J Inflamm (Lond). 2015 Feb 19;12:15. doi: 10.1186/s12950-015-0060-9. eCollection 2015.

15.

Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.

Marcone S, Haughton K, Simpson PJ, Belton O, Fitzgerald DJ.

J Inflamm (Lond). 2015 Jan 20;12(1):1. doi: 10.1186/s12950-014-0044-1. eCollection 2015.

16.

Conjugated linoleic acid targets β2 integrin expression to suppress monocyte adhesion.

de Gaetano M, Dempsey E, Marcone S, James WG, Belton O.

J Immunol. 2013 Oct 15;191(8):4326-36. doi: 10.4049/jimmunol.1300990. Epub 2013 Sep 18.

17.

Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid.

McCarthy C, Lieggi NT, Barry D, Mooney D, de Gaetano M, James WG, McClelland S, Barry MC, Escoubet-Lozach L, Li AC, Glass CK, Fitzgerald DJ, Belton O.

EMBO Mol Med. 2013 Sep;5(9):1443-57. doi: 10.1002/emmm.201302587. Epub 2013 Aug 21.

18.

IL-10 mediates the immunoregulatory response in conjugated linoleic acid-induced regression of atherosclerosis.

McCarthy C, Duffy MM, Mooney D, James WG, Griffin MD, Fitzgerald DJ, Belton O.

FASEB J. 2013 Feb;27(2):499-510. doi: 10.1096/fj.12-215442. Epub 2012 Oct 15.

PMID:
23070607
19.

Divergent effects of a CLA-enriched beef diet on metabolic health in ApoE-/- and ob/ob mice.

Reynolds CM, Toomey S, McBride R, McMonagle J, Morine MJ, Belton O, Moloney AP, Roche HM.

J Nutr Biochem. 2013 Feb;24(2):401-11. doi: 10.1016/j.jnutbio.2011.12.006. Epub 2012 May 22.

PMID:
22626767
20.

Effects of conjugated linoleic acid isomers on monocyte, macrophage and foam cell phenotype in atherosclerosis.

Mooney D, McCarthy C, Belton O.

Prostaglandins Other Lipid Mediat. 2012 Aug;98(3-4):56-62. doi: 10.1016/j.prostaglandins.2011.12.006. Epub 2011 Dec 31. Review.

PMID:
22230216
21.

Mesenchymal stem cell inhibition of T-helper 17 cell- differentiation is triggered by cell-cell contact and mediated by prostaglandin E2 via the EP4 receptor.

Duffy MM, Pindjakova J, Hanley SA, McCarthy C, Weidhofer GA, Sweeney EM, English K, Shaw G, Murphy JM, Barry FP, Mahon BP, Belton O, Ceredig R, Griffin MD.

Eur J Immunol. 2011 Oct;41(10):2840-51. doi: 10.1002/eji.201141499. Epub 2011 Aug 30.

22.

SorLA modulates atheroprotective properties of CLA by regulating monocyte migration.

McCarthy C, O'Gaora P, James WG, de Gaetano M, McClelland S, Fitzgerald DJ, Belton O.

Atherosclerosis. 2010 Dec;213(2):400-7. doi: 10.1016/j.atherosclerosis.2010.09.025. Epub 2010 Oct 20. Erratum in: Atherosclerosis. 2011 May;216(1):250.

PMID:
20970138
23.

Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell.

McClelland S, Cox C, O'Connor R, de Gaetano M, McCarthy C, Cryan L, Fitzgerald D, Belton O.

Atherosclerosis. 2010 Jul;211(1):96-102. doi: 10.1016/j.atherosclerosis.2010.02.003. Epub 2010 Feb 10.

PMID:
20223456
24.

Contribution of cyclooxygenase-1 to thromboxane formation, platelet-vessel wall interactions and atherosclerosis in the ApoE null mouse.

McClelland S, Gawaz M, Kennerknecht E, Konrad CS, Sauer S, Schuerzinger K, Massberg S, Fitzgerald DJ, Belton O.

Atherosclerosis. 2009 Jan;202(1):84-91. doi: 10.1016/j.atherosclerosis.2008.04.016. Epub 2008 Apr 23.

PMID:
18514659
25.

Profound resolution of early atherosclerosis with conjugated linoleic acid.

Toomey S, Harhen B, Roche HM, Fitzgerald D, Belton O.

Atherosclerosis. 2006 Jul;187(1):40-9. Epub 2005 Sep 22.

PMID:
16182300
26.

Intravascular thrombosis after hypoxia-induced pulmonary hypertension: regulation by cyclooxygenase-2.

Pidgeon GP, Tamosiuniene R, Chen G, Leonard I, Belton O, Bradford A, Fitzgerald DJ.

Circulation. 2004 Oct 26;110(17):2701-7. Epub 2004 Oct 18.

PMID:
15492320
27.

Cyclooxygenase isoforms and atherosclerosis.

Belton O, Fitzgerald DJ.

Expert Rev Mol Med. 2003 Mar 7;5(9):1-18. doi: 10.1017/S1462399403005842. Review.

PMID:
14987412
28.

Cyclooxygenase isoforms and platelet vessel wall interactions in the apolipoprotein E knockout mouse model of atherosclerosis.

Belton OA, Duffy A, Toomey S, Fitzgerald DJ.

Circulation. 2003 Dec 16;108(24):3017-23. Epub 2003 Nov 24.

PMID:
14638539
29.

Characterization of the proteins released from activated platelets leads to localization of novel platelet proteins in human atherosclerotic lesions.

Coppinger JA, Cagney G, Toomey S, Kislinger T, Belton O, McRedmond JP, Cahill DJ, Emili A, Fitzgerald DJ, Maguire PB.

Blood. 2004 Mar 15;103(6):2096-104. Epub 2003 Nov 20.

30.

Inhibition of PGE2 production by nimesulide compared with diclofenac in the acutely inflamed joint of patients with arthritis.

Duffy T, Belton O, Bresnihan B, FitzGerald O, FitzGerald D.

Drugs. 2003;63 Suppl 1:31-6.

PMID:
14506909
31.

Regression of pre-established atherosclerosis in the apoE-/- mouse by conjugated linoleic acid.

Toomey S, Roche H, Fitzgerald D, Belton O.

Biochem Soc Trans. 2003 Oct;31(Pt 5):1075-9. Review.

PMID:
14505483
32.

Cyclooxygenase-2 inhibitors and atherosclerosis.

Belton O, Fitzgerald D.

J Am Coll Cardiol. 2003 May 21;41(10):1820-2. No abstract available.

33.

Induction of cyclooxygenase-1 and -2 modulates angiogenic responses to engagement of alphavbeta3.

Murphy JF, Steele C, Belton O, Fitzgerald DJ.

Br J Haematol. 2003 Apr;121(1):157-64.

PMID:
12670347
34.

Cyclooxygenase isozyme expression and intimal hyperplasia in a rat model of balloon angioplasty.

Connolly E, Bouchier-Hayes DJ, Kaye E, Leahy A, Fitzgerald D, Belton O.

J Pharmacol Exp Ther. 2002 Feb;300(2):393-8.

PMID:
11805196
35.

Cyclooxygenase-1 and -2-dependent prostacyclin formation in patients with atherosclerosis.

Belton O, Byrne D, Kearney D, Leahy A, Fitzgerald DJ.

Circulation. 2000 Aug 22;102(8):840-5.

PMID:
10952950
36.

Aedes togoi comes aboard.

Belton P, Belton OC.

J Am Mosq Control Assoc. 1990 Jun;6(2):328-9.

PMID:
2370542

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