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Items: 32

1.

Complete chemical modification of amine and acid functional groups of peptides and small proteins.

Krusemark CJ, Frey BL, Smith LM, Belshaw PJ.

Methods Mol Biol. 2011;753:77-91. doi: 10.1007/978-1-61779-148-2_6.

2.

Ion-Ion Reactions with Fixed-Charge Modified Proteins to Produce Ions in a Single, Very High Charge State.

Frey BL, Krusemark CJ, Ledvina AR, Coon JJ, Belshaw PJ, Smith LM.

Int J Mass Spectrom. 2008 Oct 1;276(2-3):136-143.

3.

Modifying the charge state distribution of proteins in electrospray ionization mass spectrometry by chemical derivatization.

Krusemark CJ, Frey BL, Belshaw PJ, Smith LM.

J Am Soc Mass Spectrom. 2009 Sep;20(9):1617-25. doi: 10.1016/j.jasms.2009.04.017. Epub 2009 May 4.

4.

Global amine and acid functional group modification of proteins.

Krusemark CJ, Ferguson JT, Wenger CD, Kelleher NL, Belshaw PJ.

Anal Chem. 2008 Feb 1;80(3):713-20. doi: 10.1021/ac7019317. Epub 2008 Jan 10.

5.

Covalent labelling of fusion proteins in live cells via an engineered receptor-ligand pair.

Krusemark CJ, Belshaw PJ.

Org Biomol Chem. 2007 Jul 21;5(14):2201-4. Epub 2007 Jun 13.

PMID:
17609747
6.

Relative quantification of carboxylic acid metabolites by liquid chromatography-mass spectrometry using isotopic variants of cholamine.

Lamos SM, Shortreed MR, Frey BL, Belshaw PJ, Smith LM.

Anal Chem. 2007 Jul 15;79(14):5143-9. Epub 2007 Jun 12.

7.

Ligand-regulated peptide aptamers that inhibit the 5'-AMP-activated protein kinase.

Miller RA, Binkowski BF, Belshaw PJ.

J Mol Biol. 2007 Jan 26;365(4):945-57. Epub 2006 Jul 26.

8.

Ionizable isotopic labeling reagent for relative quantification of amine metabolites by mass spectrometry.

Shortreed MR, Lamos SM, Frey BL, Phillips MF, Patel M, Belshaw PJ, Smith LM.

Anal Chem. 2006 Sep 15;78(18):6398-403.

PMID:
16970314
9.

Mixed isotope photoaffinity reagents for identification of small-molecule targets by mass spectrometry.

Lamos SM, Krusemark CJ, McGee CJ, Scalf M, Smith LM, Belshaw PJ.

Angew Chem Int Ed Engl. 2006 Jun 26;45(26):4329-33. No abstract available.

PMID:
16733838
10.

Spatial photorelease of oligonucleotides, using a safety-catch photolabile linker.

Flickinger ST, Patel M, Binkowski BF, Lowe AM, Li MH, Kim C, Cerrina F, Belshaw PJ.

Org Lett. 2006 May 25;8(11):2357-60.

PMID:
16706525
11.
12.
13.

Correcting errors in synthetic DNA through consensus shuffling.

Binkowski BF, Richmond KE, Kaysen J, Sussman MR, Belshaw PJ.

Nucleic Acids Res. 2005 Mar 30;33(6):e55.

14.

Light-directed radial combinatorial chemistry: orthogonal safety-catch protecting groups for the synthesis of small molecule microarrays.

Shaginian A, Patel M, Li MH, Flickinger ST, Kim C, Cerrina F, Belshaw PJ.

J Am Chem Soc. 2004 Dec 29;126(51):16704-5.

PMID:
15612691
15.

Amplification and assembly of chip-eluted DNA (AACED): a method for high-throughput gene synthesis.

Richmond KE, Li MH, Rodesch MJ, Patel M, Lowe AM, Kim C, Chu LL, Venkataramaian N, Flickinger SF, Kaysen J, Belshaw PJ, Sussman MR, Cerrina F.

Nucleic Acids Res. 2004 Sep 24;32(17):5011-8. Print 2004.

16.

Solid-phase synthesis of dihydrovirginiamycin S1, a streptogramin B antibiotic.

Shaginian A, Rosen MC, Binkowski BF, Belshaw PJ.

Chemistry. 2004 Sep 6;10(17):4334-40.

PMID:
15352116
17.

TRAM linker: a safety-catch linker for the traceless release of acrylamides.

Ciolli CJ, Kalagher S, Belshaw PJ.

Org Lett. 2004 Jun 10;6(12):1891-4.

PMID:
15176776
18.
19.

Selective inhibition of engineered receptors via proximity-accelerated alkylation.

Levitsky K, Ciolli CJ, Belshaw PJ.

Org Lett. 2003 Mar 6;5(5):693-6.

PMID:
12605492
20.

Thiazole and oxazole peptides: biosynthesis and molecular machinery.

Roy RS, Gehring AM, Milne JC, Belshaw PJ, Walsh CT.

Nat Prod Rep. 1999 Apr;16(2):249-63. Review. No abstract available.

PMID:
10331285
21.

Aminoacyl-CoAs as probes of condensation domain selectivity in nonribosomal peptide synthesis.

Belshaw PJ, Walsh CT, Stachelhaus T.

Science. 1999 Apr 16;284(5413):486-9.

22.

Kinetics and regioselectivity of peptide-to-heterocycle conversions by microcin B17 synthetase.

Belshaw PJ, Roy RS, Kelleher NL, Walsh CT.

Chem Biol. 1998 Jul;5(7):373-84.

24.

Oligomerization activates c-Raf-1 through a Ras-dependent mechanism.

Luo Z, Tzivion G, Belshaw PJ, Vavvas D, Marshall M, Avruch J.

Nature. 1996 Sep 12;383(6596):181-5.

PMID:
8774885
25.

Controlling programmed cell death with a cyclophilin-cyclosporin-based chemical inducer of dimerization.

Belshaw PJ, Spencer DM, Crabtree GR, Schreiber SL.

Chem Biol. 1996 Sep;3(9):731-8.

26.

Functional analysis of Fas signaling in vivo using synthetic inducers of dimerization.

Spencer DM, Belshaw PJ, Chen L, Ho SN, Randazzo F, Crabtree GR, Schreiber SL.

Curr Biol. 1996 Jul 1;6(7):839-47.

27.

Controlling protein association and subcellular localization with a synthetic ligand that induces heterodimerization of proteins.

Belshaw PJ, Ho SN, Crabtree GR, Schreiber SL.

Proc Natl Acad Sci U S A. 1996 May 14;93(10):4604-7.

28.

Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells.

Goldfeld AE, Tsai E, Kincaid R, Belshaw PJ, Schrieber SL, Strominger JL, Rao A.

J Exp Med. 1994 Aug 1;180(2):763-8.

29.

Cyclosporin A inhibits CD40 ligand expression in T lymphocytes.

Fuleihan R, Ramesh N, Horner A, Ahern D, Belshaw PJ, Alberg DG, Stamenkovic I, Harmon W, Geha RS.

J Clin Invest. 1994 Mar;93(3):1315-20.

30.

Crystal structures of cyclophilin A complexed with cyclosporin A and N-methyl-4-[(E)-2-butenyl]-4,4-dimethylthreonine cyclosporin A.

Ke H, Mayrose D, Belshaw PJ, Alberg DG, Schreiber SL, Chang ZY, Etzkorn FA, Ho S, Walsh CT.

Structure. 1994 Jan 15;2(1):33-44.

PMID:
8075981
31.

Cyclosporine- and FK506-induced sympathetic activation correlates with calcineurin-mediated inhibition of T-cell signaling.

Lyson T, Ermel LD, Belshaw PJ, Alberg DG, Schreiber SL, Victor RG.

Circ Res. 1993 Sep;73(3):596-602.

PMID:
7688670
32.

Inhibition of T cell signaling by immunophilin-ligand complexes correlates with loss of calcineurin phosphatase activity.

Liu J, Albers MW, Wandless TJ, Luan S, Alberg DG, Belshaw PJ, Cohen P, MacKintosh C, Klee CB, Schreiber SL.

Biochemistry. 1992 Apr 28;31(16):3896-901.

PMID:
1373650

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