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Items: 1 to 50 of 159

1.

Capillary Proliferation in Systemic-Sclerosis-Related Pulmonary Fibrosis: Association with Pulmonary Hypertension.

Seki A, Anklesaria Z, Saggar R, Dodson MW, Schwab K, Liu MC, Charan Ashana D, Miller WD, Vangala S, DerHovanessian A, Channick R, Shaikh F, Belperio JA, Weigt SS, Lynch JP, Ross DJ, Sullivan L, Khanna D, Shapiro SS, Sager J, Gargani L, Stanziola A, Bossone E, Schraufnagel DE, Fishbein G, Xu H, Fishbein MC, Wallace WD, Saggar R.

ACR Open Rheumatol. 2019 Mar 15;1(1):26-36. doi: 10.1002/acr2.1003. eCollection 2019 Mar.

2.

Endotype-phenotyping may predict a treatment response in progressive fibrosing interstitial lung disease.

Hoffmann-Vold AM, Weigt SS, Saggar R, Palchevskiy V, Volkmann ER, Liang LL, Ross D, Ardehali A, Lynch JP 3rd, Belperio JA.

EBioMedicine. 2019 Dec;50:379-386. doi: 10.1016/j.ebiom.2019.10.050. Epub 2019 Nov 12.

3.

Amphiregulin contributes to airway remodeling in chronic allograft dysfunction after lung transplantation.

Todd JL, Kelly FL, Nagler A, Banner K, Pavlisko EN, Belperio JA, Brass D, Weigt SS, Palmer SM.

Am J Transplant. 2020 Mar;20(3):825-833. doi: 10.1111/ajt.15667. Epub 2019 Dec 1.

PMID:
31665560
4.

Mitochondrial DNA Stimulates TLR9-Dependent Neutrophil Extracellular Trap Formation in Primary Graft Dysfunction.

Mallavia B, Liu F, Lefrançais E, Cleary SJ, Kwaan N, Tian JJ, Magnen M, Sayah DM, Soong A, Chen J, Saggar R, Shino MY, Ross DJ, Derhovanessian A, Lynch JP 3rd, Ardehali A, Weigt SS, Belperio JA, Hays SR, Golden JA, Leard LE, Shah RJ, Kleinhenz ME, Venado A, Kukreja J, Singer JP, Looney MR.

Am J Respir Cell Mol Biol. 2020 Mar;62(3):364-372. doi: 10.1165/rcmb.2019-0140OC.

PMID:
31647878
5.

Peripheral blood proteomic profiling of idiopathic pulmonary fibrosis biomarkers in the multicentre IPF-PRO Registry.

Todd JL, Neely ML, Overton R, Durham K, Gulati M, Huang H, Roman J, Newby LK, Flaherty KR, Vinisko R, Liu Y, Roy J, Schmid R, Strobel B, Hesslinger C, Leonard TB, Noth I, Belperio JA, Palmer SM; IPF-PRO Registry investigators.

Respir Res. 2019 Oct 22;20(1):227. doi: 10.1186/s12931-019-1190-z.

6.

Prediction of idiopathic pulmonary fibrosis progression using early quantitative changes on CT imaging for a short term of clinical 18-24-month follow-ups.

Kim GHJ, Weigt SS, Belperio JA, Brown MS, Shi Y, Lai JH, Goldin JG.

Eur Radiol. 2020 Feb;30(2):726-734. doi: 10.1007/s00330-019-06402-6. Epub 2019 Aug 26.

PMID:
31451973
7.

Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection.

Weigt SS, Wang X, Palchevskiy V, Li X, Patel N, Ross DJ, Reynolds J, Shah PD, Danziger-Isakov LA, Sweet SC, Singer LG, Budev M, Palmer S, Belperio JA.

J Heart Lung Transplant. 2019 Aug;38(8):845-855. doi: 10.1016/j.healun.2019.05.001. Epub 2019 May 7.

PMID:
31122726
8.

CCR4 expression on host T cells is a driver for alloreactive responses and lung rejection.

Palchevskiy V, Xue YY, Kern R, Weigt SS, Gregson AL, Song SX, Fishbein MC, Hogaboam CM, Sayah DM, Lynch JP 3rd, Keane MP, Brooks DG, Belperio JA.

JCI Insight. 2019 May 14;5. pii: 121782. doi: 10.1172/jci.insight.121782.

9.

Patient Registries in Idiopathic Pulmonary Fibrosis.

Culver DA, Behr J, Belperio JA, Corte TJ, de Andrade JA, Flaherty KR, Gulati M, Huie TJ, Lancaster LH, Roman J, Ryerson CJ, Kim HJ.

Am J Respir Crit Care Med. 2019 Jul 15;200(2):160-167. doi: 10.1164/rccm.201902-0431CI. Review.

10.

Augmented concentrations of CX3CL1 are associated with interstitial lung disease in systemic sclerosis.

Hoffmann-Vold AM, Weigt SS, Palchevskiy V, Volkmann E, Saggar R, Li N, Midtvedt Ø, Lund MB, Garen T, Fishbein MC, Ardehali A, Ross DJ, Ueland T, Aukrust P, Lynch JP 3rd, Elashoff RM, Molberg Ø, Belperio JA.

PLoS One. 2018 Nov 20;13(11):e0206545. doi: 10.1371/journal.pone.0206545. eCollection 2018.

11.

Granulomatosis with Polyangiitis (Wegener's Granulomatosis): Evolving Concepts in Treatment.

Lynch JP 3rd, Derhovanessian A, Tazelaar H, Belperio JA.

Semin Respir Crit Care Med. 2018 Aug;39(4):434-458. doi: 10.1055/s-0038-1660874. Epub 2018 Nov 7. Review.

PMID:
30404111
12.

CCL21 as a Potential Serum Biomarker for Pulmonary Arterial Hypertension in Systemic Sclerosis.

Hoffmann-Vold AM, Hesselstrand R, Fretheim H, Ueland T, Andreassen AK, Brunborg C, Palchevskiy V, Midtvedt Ø, Garen T, Aukrust P, Belperio JA, Molberg Ø.

Arthritis Rheumatol. 2018 Oct;70(10):1644-1653. doi: 10.1002/art.40534. Epub 2018 Aug 30.

13.

Fungal Infections Complicating Lung Transplantation.

Clark NM, Weigt SS, Fishbein MC, Kubak B, Belperio JA, Lynch JP 3rd.

Semin Respir Crit Care Med. 2018 Apr;39(2):227-254. doi: 10.1055/s-0037-1617443. Epub 2018 Mar 26. Review.

PMID:
29579774
14.

Chronic Lung Allograft Dysfunction: Evolving Concepts and Therapies.

DerHovanessian A, Wallace WD, Lynch JP 3rd, Belperio JA, Weigt SS.

Semin Respir Crit Care Med. 2018 Apr;39(2):155-171. doi: 10.1055/s-0037-1618567. Epub 2018 Mar 26. Review.

PMID:
29579768
15.

Lung Transplantation: Controversies and Evolving Concepts.

Belperio JA, Glanville AR.

Semin Respir Crit Care Med. 2018 Apr;39(2):115-116. doi: 10.1055/s-0037-1617413. Epub 2018 Mar 26. No abstract available.

PMID:
29579764
16.

Silencing the Snail-Dependent RNA Splice Regulator ESRP1 Drives Malignant Transformation of Human Pulmonary Epithelial Cells.

Walser TC, Jing Z, Tran LM, Lin YQ, Yakobian N, Wang G, Krysan K, Zhu LX, Sharma S, Lee MH, Belperio JA, Ooi AT, Gomperts BN, Shay JW, Larsen JE, Minna JD, Hong LS, Fishbein MC, Dubinett SM.

Cancer Res. 2018 Apr 15;78(8):1986-1999. doi: 10.1158/0008-5472.CAN-17-0315. Epub 2018 Feb 5.

17.

The Impact of Allograft CXCL9 during Respiratory Infection on the Risk of Chronic Lung Allograft Dysfunction.

Shino MY, DerHovanessian A, Sayah DM, Saggar R, Ying Xue Y, Ardehali A, Stripp BR, Ross DJ, Lynch JP 3rd, Elashoff RM, Weigt SS, Belperio JA.

OBM Transplant. 2018;2(4). pii: 029. doi: 10.21926/obm.transplant.1804029. Epub 2018 Nov 30.

18.

Gene Expression Profiling of Bronchoalveolar Lavage Cells During Aspergillus Colonization of the Lung Allograft.

Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Lynch JP 3rd, Saggar R, Ross DJ, Kubak BM, Ardehali A, Palmer S, Husain S, Belperio JA.

Transplantation. 2018 Jun;102(6):986-993. doi: 10.1097/TP.0000000000002058.

19.

Pulmonary Hypertension Complicating Connective Tissue Disease.

Volkmann ER, Chung A, Saggar R, Belperio JA, Lynch JP 3rd.

Semin Respir Crit Care Med. 2017 Oct;38(5):619-635. doi: 10.1055/s-0037-1606203. Epub 2017 Oct 15. Review. No abstract available.

PMID:
29032565
20.

Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction.

Weigt SS, Wang X, Palchevskiy V, Patel N, Derhovanessian A, Shino MY, Sayah DM, Gregson AL, Lynch JP 3rd, Saggar R, Ross DJ, Ardehali A, Elashoff D, Belperio JA.

Ann Am Thorac Soc. 2017 Sep;14(Suppl_3):S252. doi: 10.1513/AnnalsATS.201608-618MG. No abstract available.

21.

Cardiac Involvement in Sarcoidosis: Evolving Concepts in Diagnosis and Treatment.

Sayah DM, Bradfield JS, Moriarty JM, Belperio JA, Lynch JP 3rd.

Semin Respir Crit Care Med. 2017 Aug;38(4):477-498. doi: 10.1055/s-0037-1602381. Epub 2017 Jul 27. Review. No abstract available.

PMID:
28750462
22.

The prognostic importance of CXCR3 chemokine during organizing pneumonia on the risk of chronic lung allograft dysfunction after lung transplantation.

Shino MY, Weigt SS, Li N, Palchevskiy V, Derhovanessian A, Saggar R, Sayah DM, Huynh RH, Gregson AL, Fishbein MC, Ardehali A, Ross DJ, Lynch JP 3rd, Elashoff RM, Belperio JA.

PLoS One. 2017 Jul 7;12(7):e0180281. doi: 10.1371/journal.pone.0180281. eCollection 2017.

23.

The Prognostic Importance of Bronchoalveolar Lavage Fluid CXCL9 During Minimal Acute Rejection on the Risk of Chronic Lung Allograft Dysfunction.

Shino MY, Weigt SS, Li N, Derhovanessian A, Sayah DM, Saggar R, Huynh RH, Gregson AL, Ardehali A, Ross DJ, Lynch JP Rd, Elashoff RM, Belperio JA.

Am J Transplant. 2018 Jan;18(1):136-144. doi: 10.1111/ajt.14397. Epub 2017 Aug 2.

24.

Inflammasomes and IL-1 biology in the pathogenesis of allograft dysfunction.

Weigt SS, Palchevskiy V, Belperio JA.

J Clin Invest. 2017 Jun 1;127(6):2022-2029. doi: 10.1172/JCI93537. Epub 2017 Jun 1. Review.

25.

Models of Lung Transplant Research: a consensus statement from the National Heart, Lung, and Blood Institute workshop.

Lama VN, Belperio JA, Christie JD, El-Chemaly S, Fishbein MC, Gelman AE, Hancock WW, Keshavjee S, Kreisel D, Laubach VE, Looney MR, McDyer JF, Mohanakumar T, Shilling RA, Panoskaltsis-Mortari A, Wilkes DS, Eu JP, Nicolls MR.

JCI Insight. 2017 May 4;2(9). pii: 93121. doi: 10.1172/jci.insight.93121. eCollection 2017 May 4. Review.

26.

Gene Expression Profiling of Bronchoalveolar Lavage Cells Preceding a Clinical Diagnosis of Chronic Lung Allograft Dysfunction.

Weigt SS, Wang X, Palchevskiy V, Gregson AL, Patel N, DerHovanessian A, Shino MY, Sayah DM, Birjandi S, Lynch JP 3rd, Saggar R, Ardehali A, Ross DJ, Palmer SM, Elashoff D, Belperio JA.

PLoS One. 2017 Jan 19;12(1):e0169894. doi: 10.1371/journal.pone.0169894. eCollection 2017.

27.

Impact of Allograft Injury Time of Onset on the Development of Chronic Lung Allograft Dysfunction After Lung Transplantation.

Shino MY, Weigt SS, Li N, Derhovanessian A, Sayah DM, Huynh RH, Saggar R, Gregson AL, Ardehali A, Ross DJ, Lynch JP 3rd, Elashoff RM, Belperio JA.

Am J Transplant. 2017 May;17(5):1294-1303. doi: 10.1111/ajt.14066. Epub 2016 Oct 31.

28.

Voriconazole increases the risk for cutaneous squamous cell carcinoma after lung transplantation.

Kolaitis NA, Duffy E, Zhang A, Lo M, Barba DT, Chen M, Soriano T, Hu J, Nabili V, Saggar R, Sayah DM, DerHovanessian A, Shino MY, Lynch JP 3rd, Kubak BM, Ardehali A, Ross DJ, Belperio JA, Elashoff D, Saggar R, Weigt SS.

Transpl Int. 2017 Jan;30(1):41-48. doi: 10.1111/tri.12865. Epub 2016 Oct 24.

29.

Graft Loss and CLAD-Onset Is Hastened by Viral Pneumonia After Lung Transplantation.

Allyn PR, Duffy EL, Humphries RM, Injean P, Weigt SS, Saggar R, Shino MY, Lynch JP 3rd, Ardehali A, Kubak B, Tseng CH, Belperio JA, Ross DJ, Gregson AL.

Transplantation. 2016 Nov;100(11):2424-2431.

30.

Utility of Transbronchial vs Surgical Lung Biopsy in the Diagnosis of Suspected Fibrotic Interstitial Lung Disease.

Sheth JS, Belperio JA, Fishbein MC, Kazerooni EA, Lagstein A, Murray S, Myers JL, Simon RH, Sisson TH, Sundaram B, White ES, Xia M, Zisman D, Flaherty KR.

Chest. 2017 Feb;151(2):389-399. doi: 10.1016/j.chest.2016.09.028. Epub 2016 Oct 8.

31.

Herpesvirus Respiratory Infections in Immunocompromised Patients: Epidemiology, Management, and Outcomes.

Reid GE, Lynch JP 3rd, Weigt S, Sayah D, Belperio JA, Grim SA, Clark NM.

Semin Respir Crit Care Med. 2016 Aug;37(4):603-30. doi: 10.1055/s-0036-1584793. Epub 2016 Aug 3. Review.

PMID:
27486740
32.

CD4(+)CD25(hi)Foxp3(+) Cells Exacerbate Bleomycin-Induced Pulmonary Fibrosis.

Birjandi SZ, Palchevskiy V, Xue YY, Nunez S, Kern R, Weigt SS, Lynch JP 3rd, Chatila TA, Belperio JA.

Am J Pathol. 2016 Aug;186(8):2008-2020. doi: 10.1016/j.ajpath.2016.03.020. Epub 2016 Jun 16.

33.

Idiopathic Pulmonary Fibrosis: Epidemiology, Clinical Features, Prognosis, and Management.

Lynch JP 3rd, Huynh RH, Fishbein MC, Saggar R, Belperio JA, Weigt SS.

Semin Respir Crit Care Med. 2016 Jun;37(3):331-57. doi: 10.1055/s-0036-1582011. Epub 2016 May 27. Review.

PMID:
27231859
34.

Lung Transplant Outcomes in Systemic Sclerosis with Significant Esophageal Dysfunction. A Comprehensive Single-Center Experience.

Miele CH, Schwab K, Saggar R, Duffy E, Elashoff D, Tseng CH, Weigt S, Charan D, Abtin F, Johannes J, Derhovanessian A, Conklin J, Ghassemi K, Khanna D, Siddiqui O, Ardehali A, Hunter C, Kwon M, Biniwale R, Lo M, Volkmann E, Torres Barba D, Belperio JA, Sayah D, Mahrer T, Furst DE, Kafaja S, Clements P, Shino M, Gregson A, Kubak B, Lynch JP 3rd, Ross D, Saggar R.

Ann Am Thorac Soc. 2016 Jun;13(6):793-802. doi: 10.1513/AnnalsATS.201512-806OC.

35.

Transitions to different patterns of interstitial lung disease in scleroderma with and without treatment.

Kim HJ, Tashkin DP, Gjertson DW, Brown MS, Kleerup E, Chong S, Belperio JA, Roth MD, Abtin F, Elashoff R, Tseng CH, Khanna D, Goldin JG.

Ann Rheum Dis. 2016 Jul;75(7):1367-71. doi: 10.1136/annrheumdis-2015-208929. Epub 2016 Jan 12.

PMID:
26757749
36.

Proinflammatory high-density lipoprotein results from oxidized lipid mediators in the pathogenesis of both idiopathic and associated types of pulmonary arterial hypertension.

Ross DJ, Hough G, Hama S, Aboulhosn J, Belperio JA, Saggar R, Van Lenten BJ, Ardehali A, Eghbali M, Reddy S, Fogelman AM, Navab M.

Pulm Circ. 2015 Dec;5(4):640-8. doi: 10.1086/683695.

37.

The Role of TGF-β in the Association Between Primary Graft Dysfunction and Bronchiolitis Obliterans Syndrome.

DerHovanessian A, Weigt SS, Palchevskiy V, Shino MY, Sayah DM, Gregson AL, Noble PW, Palmer SM, Fishbein MC, Kubak BM, Ardehali A, Ross DJ, Saggar R, Lynch JP 3rd, Elashoff RM, Belperio JA.

Am J Transplant. 2016 Feb;16(2):640-9. doi: 10.1111/ajt.13475. Epub 2015 Oct 13.

38.

Altered Exosomal RNA Profiles in Bronchoalveolar Lavage from Lung Transplants with Acute Rejection.

Gregson AL, Hoji A, Injean P, Poynter ST, Briones C, Palchevskiy V, Weigt SS, Shino MY, Derhovanessian A, Sayah D, Saggar R, Ross D, Ardehali A, Lynch JP 3rd, Belperio JA.

Am J Respir Crit Care Med. 2015 Dec 15;192(12):1490-503. doi: 10.1164/rccm.201503-0558OC.

39.

CXCL9 Regulates TGF-β1-Induced Epithelial to Mesenchymal Transition in Human Alveolar Epithelial Cells.

O'Beirne SL, Walsh SM, Fabre A, Reviriego C, Worrell JC, Counihan IP, Lumsden RV, Cramton-Barnes J, Belperio JA, Donnelly SC, Boylan D, Marchal-Sommé J, Kane R, Keane MP.

J Immunol. 2015 Sep 15;195(6):2788-96. doi: 10.4049/jimmunol.1402008. Epub 2015 Aug 12.

40.

Lung transplantation for cystic fibrosis: results, indications, complications, and controversies.

Lynch JP 3rd, Sayah DM, Belperio JA, Weigt SS.

Semin Respir Crit Care Med. 2015 Apr;36(2):299-320. doi: 10.1055/s-0035-1547347. Epub 2015 Mar 31. Review.

41.

Staphylococcus via an interaction with the ELR+ CXC chemokine ENA-78 is associated with BOS.

Gregson AL, Wang X, Injean P, Weigt SS, Shino M, Sayah D, DerHovanessian A, Lynch JP 3rd, Ross DJ, Saggar R, Ardehali A, Li G, Elashoff R, Belperio JA.

Am J Transplant. 2015 Mar;15(3):792-9. doi: 10.1111/ajt.13029. Epub 2015 Feb 12.

42.

CXCR3 Requirement for the Interleukin-13-Mediated Up-Regulation of Interleukin-13Rα2 in Pulmonary Fibroblasts.

Barnes JC, Lumsden RV, Worrell J, Counihan IP, O'Beirne SL, Belperio JA, Fabre A, Donnelly SC, Boylan D, Kane R, Keane MP.

Am J Respir Cell Mol Biol. 2015 Aug;53(2):217-25. doi: 10.1165/rcmb.2013-0433OC.

43.

Neutrophil extracellular traps are pathogenic in primary graft dysfunction after lung transplantation.

Sayah DM, Mallavia B, Liu F, Ortiz-Muñoz G, Caudrillier A, DerHovanessian A, Ross DJ, Lynch JP 3rd, Saggar R, Ardehali A; Lung Transplant Outcomes Group Investigators, Ware LB, Christie JD, Belperio JA, Looney MR.

Am J Respir Crit Care Med. 2015 Feb 15;191(4):455-63. doi: 10.1164/rccm.201406-1086OC.

44.

Sarcoidosis-associated pulmonary hypertension and lung transplantation for sarcoidosis.

Shino MY, Lynch Iii JP, Fishbein MC, McGraw C, Oyama J, Belperio JA, Saggar R.

Semin Respir Crit Care Med. 2014 Jun;35(3):362-71. doi: 10.1055/s-0034-1376863. Epub 2014 Jul 9. Review.

45.

Interstitial lung disease in patients with hepatopulmonary syndrome: a case series and new observations.

Shahangian S, Shino MY, Barjaktarevic I, Susanto I, Belperio JA, Fishbein MC, Wang T.

Lung. 2014 Jun;192(3):421-7. doi: 10.1007/s00408-014-9571-z. Epub 2014 Mar 30.

PMID:
24682307
46.

Changes in right heart haemodynamics and echocardiographic function in an advanced phenotype of pulmonary hypertension and right heart dysfunction associated with pulmonary fibrosis.

Saggar R, Khanna D, Vaidya A, Derhovanessian A, Maranian P, Duffy E, Belperio JA, Weigt SS, Dua S, Shapiro SS, Goldin JG, Abtin F, Lynch JP 3rd, Ross DJ, Forfia PR, Saggar R.

Thorax. 2014 Feb;69(2):123-9. doi: 10.1136/thoraxjnl-2013-204150.

PMID:
24431095
47.

Preoperative cardiac variables of diastolic dysfunction and clinical outcomes in lung transplant recipients.

Yadlapati A, Lynch JP 3rd, Saggar R, Ross D, Belperio JA, Weigt S, Ardehali A, Grogan T, Yang EH, Aboulhosn J.

J Transplant. 2013;2013:391620. doi: 10.1155/2013/391620. Epub 2013 Sep 12.

48.

CXCR3 ligands are associated with the continuum of diffuse alveolar damage to chronic lung allograft dysfunction.

Shino MY, Weigt SS, Li N, Palchevskiy V, Derhovanessian A, Saggar R, Sayah DM, Gregson AL, Fishbein MC, Ardehali A, Ross DJ, Lynch JP 3rd, Elashoff RM, Belperio JA.

Am J Respir Crit Care Med. 2013 Nov 1;188(9):1117-25. doi: 10.1164/rccm.201305-0861OC.

49.

Pulmonary hypertension complicating interstitial lung disease and COPD.

Shino MY, Lynch JP 3rd, Saggar R, Abtin F, Belperio JA, Saggar R.

Semin Respir Crit Care Med. 2013 Oct;34(5):600-19. doi: 10.1055/s-0033-1356548. Epub 2013 Sep 13. Review.

PMID:
24037628
50.

Pulmonary hypertension complicating connective tissue disease.

Lynch JP 3rd, Belperio JA, Saggar R, Fishbein MC, Saggar R.

Semin Respir Crit Care Med. 2013 Oct;34(5):581-99. doi: 10.1055/s-0033-1356547. Epub 2013 Sep 13.

PMID:
24037627

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