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Items: 50

1.

Novel strategy for oral peptide delivery in incretin-based diabetes treatment.

Xu Y, Van Hul M, Suriano F, Préat V, Cani PD, Beloqui A.

Gut. 2019 Aug 10. pii: gutjnl-2019-319146. doi: 10.1136/gutjnl-2019-319146. [Epub ahead of print]

2.

Impact of Polymer Bioconjugation on Protein Stability and Activity Investigated with Discrete Conjugates: Alternatives to PEGylation.

Morgenstern J, Gil Alvaradejo G, Bluthardt N, Beloqui A, Delaittre G, Hubbuch J.

Biomacromolecules. 2018 Nov 12;19(11):4250-4262. doi: 10.1021/acs.biomac.8b01020. Epub 2018 Oct 5.

PMID:
30222929
3.

A simple route to highly active single-enzyme nanogels.

Beloqui A, Kobitski AY, Nienhaus GU, Delaittre G.

Chem Sci. 2017 Dec 1;9(4):1006-1013. doi: 10.1039/c7sc04438k. eCollection 2018 Jan 28.

4.

The stimulation of GLP-1 secretion and delivery of GLP-1 agonists via nanostructured lipid carriers.

Shrestha N, Bouttefeux O, Vanvarenberg K, Lundquist P, Cunarro J, Tovar S, Khodus G, Andersson E, Keita ÅV, Gonzalez Dieguez C, Artursson P, Préat V, Beloqui A.

Nanoscale. 2018 Jan 3;10(2):603-613. doi: 10.1039/c7nr07736j.

PMID:
29235598
5.

Size Effect on Lipid Nanocapsule-Mediated GLP-1 Secretion from Enteroendocrine L Cells.

Xu Y, Carradori D, Alhouayek M, Muccioli GG, Cani PD, Préat V, Beloqui A.

Mol Pharm. 2018 Jan 2;15(1):108-115. doi: 10.1021/acs.molpharmaceut.7b00742. Epub 2017 Dec 15.

PMID:
29226685
6.

Nitrilotriacetic Amine-Functionalized Polymeric Core-Shell Nanoparticles as Enzyme Immobilization Supports.

Keller D, Beloqui A, Martínez-Martínez M, Ferrer M, Delaittre G.

Biomacromolecules. 2017 Sep 11;18(9):2777-2788. doi: 10.1021/acs.biomac.7b00677. Epub 2017 Aug 15.

PMID:
28731680
7.

A human intestinal M-cell-like model for investigating particle, antigen and microorganism translocation.

Beloqui A, Brayden DJ, Artursson P, Préat V, des Rieux A.

Nat Protoc. 2017 Jul;12(7):1387-1399. doi: 10.1038/nprot.2017.041. Epub 2017 Jun 15.

PMID:
28617450
8.

A Mechanistic Study on Nanoparticle-Mediated Glucagon-Like Peptide-1 (GLP-1) Secretion from Enteroendocrine L Cells.

Beloqui A, Alhouayek M, Carradori D, Vanvarenberg K, Muccioli GG, Cani PD, Préat V.

Mol Pharm. 2016 Dec 5;13(12):4222-4230. Epub 2016 Nov 18.

PMID:
27934480
9.

The interaction of protamine nanocapsules with the intestinal epithelium: A mechanistic approach.

Thwala LN, Beloqui A, Csaba NS, González-Touceda D, Tovar S, Dieguez C, Alonso MJ, Préat V.

J Control Release. 2016 Dec 10;243:109-120. doi: 10.1016/j.jconrel.2016.10.002. Epub 2016 Oct 6.

PMID:
27720993
10.

Mechanisms of transport of polymeric and lipidic nanoparticles across the intestinal barrier.

Beloqui A, des Rieux A, Préat V.

Adv Drug Deliv Rev. 2016 Nov 15;106(Pt B):242-255. doi: 10.1016/j.addr.2016.04.014. Epub 2016 Apr 23. Review.

PMID:
27117710
11.

A comparative study of curcumin-loaded lipid-based nanocarriers in the treatment of inflammatory bowel disease.

Beloqui A, Memvanga PB, Coco R, Reimondez-Troitiño S, Alhouayek M, Muccioli GG, Alonso MJ, Csaba N, de la Fuente M, Préat V.

Colloids Surf B Biointerfaces. 2016 Jul 1;143:327-335. doi: 10.1016/j.colsurfb.2016.03.038. Epub 2016 Mar 16.

PMID:
27022873
12.

Cyclosporine A-loaded lipid nanoparticles in inflammatory bowel disease.

Guada M, Beloqui A, Alhouayek M, Muccioli GG, Dios-Viéitez Mdel C, Préat V, Blanco-Prieto MJ.

Int J Pharm. 2016 Apr 30;503(1-2):196-8. doi: 10.1016/j.ijpharm.2016.03.012. Epub 2016 Mar 10.

PMID:
26972380
13.

Targeting Inflammatory Bowel Diseases by Nanocarriers Loaded with Small and Biopharmaceutical Anti-Inflammatory Drugs.

Beloqui A, Coco R, Préat V.

Curr Pharm Des. 2016;22(40):6192-6206. Review.

PMID:
26864312
14.

Single-Molecule Encapsulation: A Straightforward Route to Highly Stable and Printable Enzymes.

Beloqui A, Baur S, Trouillet V, Welle A, Madsen J, Bastmeyer M, Delaittre G.

Small. 2016 Apr 6;12(13):1716-22. doi: 10.1002/smll.201503405. Epub 2016 Feb 5.

PMID:
26849308
15.

Reformulating cyclosporine A (CsA): More than just a life cycle management strategy.

Guada M, Beloqui A, Kumar MN, Préat V, Dios-Viéitez Mdel C, Blanco-Prieto MJ.

J Control Release. 2016 Mar 10;225:269-82. doi: 10.1016/j.jconrel.2016.01.056. Epub 2016 Jan 30. Review.

PMID:
26829101
16.

Nanoparticle transport across in vitro olfactory cell monolayers.

Gartziandia O, Egusquiaguirre SP, Bianco J, Pedraz JL, Igartua M, Hernandez RM, Préat V, Beloqui A.

Int J Pharm. 2016 Feb 29;499(1-2):81-89. doi: 10.1016/j.ijpharm.2015.12.046. Epub 2015 Dec 22.

PMID:
26721725
17.

Delivery of Peptides Via the Oral Route: Diabetes Treatment by Peptide-Loaded Nanoparticles.

Bouttefeux O, Beloqui A, Preat V.

Curr Pharm Des. 2016;22(9):1161-76. Review.

PMID:
26675223
18.

Nanostructured lipid carriers: Promising drug delivery systems for future clinics.

Beloqui A, Solinís MÁ, Rodríguez-Gascón A, Almeida AJ, Préat V.

Nanomedicine. 2016 Jan;12(1):143-61. doi: 10.1016/j.nano.2015.09.004. Epub 2015 Sep 26. Review.

PMID:
26410277
19.

Algal lectin binding to core (α1-6) fucosylated N-glycans: structural basis for specificity and production of recombinant protein.

do Nascimento AS, Serna S, Beloqui A, Arda A, Sampaio AH, Walcher J, Ott D, Unverzagt C, Reichardt NC, Jimenez-Barbero J, Nascimento KS, Imberty A, Cavada BS, Varrot A.

Glycobiology. 2015 Jun;25(6):607-16. doi: 10.1093/glycob/cwv002. Epub 2015 Jan 8.

PMID:
25573275
20.

Nanostructured indium tin oxide slides for small-molecule profiling and imaging mass spectrometry of metabolites by surface-assisted laser desorption ionization MS.

López de Laorden C, Beloqui A, Yate L, Calvo J, Puigivila M, Llop J, Reichardt NC.

Anal Chem. 2015 Jan 6;87(1):431-40. doi: 10.1021/ac5025864. Epub 2014 Dec 11.

PMID:
25411795
21.

pH-sensitive nanoparticles for colonic delivery of curcumin in inflammatory bowel disease.

Beloqui A, Coco R, Memvanga PB, Ucakar B, des Rieux A, Préat V.

Int J Pharm. 2014 Oct 1;473(1-2):203-12. doi: 10.1016/j.ijpharm.2014.07.009. Epub 2014 Jul 8.

PMID:
25014369
22.

Dextran-protamine coated nanostructured lipid carriers as mucus-penetrating nanoparticles for lipophilic drugs.

Beloqui A, Solinís MÁ, des Rieux A, Préat V, Rodríguez-Gascón A.

Int J Pharm. 2014 Jul 1;468(1-2):105-11. doi: 10.1016/j.ijpharm.2014.04.027. Epub 2014 Apr 16.

PMID:
24746410
23.

Genome sequence and functional genomic analysis of the oil-degrading bacterium Oleispira antarctica.

Kube M, Chernikova TN, Al-Ramahi Y, Beloqui A, Lopez-Cortez N, Guazzaroni ME, Heipieper HJ, Klages S, Kotsyurbenko OR, Langer I, Nechitaylo TY, Lünsdorf H, Fernández M, Juárez S, Ciordia S, Singer A, Kagan O, Egorova O, Petit PA, Stogios P, Kim Y, Tchigvintsev A, Flick R, Denaro R, Genovese M, Albar JP, Reva ON, Martínez-Gomariz M, Tran H, Ferrer M, Savchenko A, Yakunin AF, Yakimov MM, Golyshina OV, Reinhardt R, Golyshin PN.

Nat Commun. 2013;4:2156. doi: 10.1038/ncomms3156.

24.

Analysis of microarrays by MALDI-TOF MS.

Beloqui A, Calvo J, Serna S, Yan S, Wilson IB, Martin-Lomas M, Reichardt NC.

Angew Chem Int Ed Engl. 2013 Jul 15;52(29):7477-81. doi: 10.1002/anie.201302455. Epub 2013 Jun 11.

PMID:
23757366
25.

Budesonide-loaded nanostructured lipid carriers reduce inflammation in murine DSS-induced colitis.

Beloqui A, Coco R, Alhouayek M, Solinís MÁ, Rodríguez-Gascón A, Muccioli GG, Préat V.

Int J Pharm. 2013 Oct 1;454(2):775-83. doi: 10.1016/j.ijpharm.2013.05.017. Epub 2013 May 18.

PMID:
23694806
26.

Fate of nanostructured lipid carriers (NLCs) following the oral route: design, pharmacokinetics and biodistribution.

Beloqui A, Solinís MÁ, Delgado A, Evora C, Isla A, Rodríguez-Gascón A.

J Microencapsul. 2014;31(1):1-8. doi: 10.3109/02652048.2013.788090. Epub 2013 Apr 30.

PMID:
23631381
27.

Biodistribution of Nanostructured Lipid Carriers (NLCs) after intravenous administration to rats: influence of technological factors.

Beloqui A, Solinís MA, Delgado A, Evora C, del Pozo-Rodríguez A, Rodríguez-Gascón A.

Eur J Pharm Biopharm. 2013 Jun;84(2):309-14. doi: 10.1016/j.ejpb.2013.01.029. Epub 2013 Feb 24.

PMID:
23461861
28.

Three-dimensional arrays using glycoPEG tags: glycan synthesis, purification and immobilisation.

Etxebarria J, Serna S, Beloqui A, Martin-Lomas M, Reichardt NC.

Chemistry. 2013 Apr 8;19(15):4776-85. doi: 10.1002/chem.201204004. Epub 2013 Feb 11.

PMID:
23401205
29.

Mechanism of transport of saquinavir-loaded nanostructured lipid carriers across the intestinal barrier.

Beloqui A, Solinís MÁ, Gascón AR, del Pozo-Rodríguez A, des Rieux A, Préat V.

J Control Release. 2013 Mar 10;166(2):115-23. doi: 10.1016/j.jconrel.2012.12.021. Epub 2012 Dec 22.

PMID:
23266764
30.

Functional metagenomics unveils a multifunctional glycosyl hydrolase from the family 43 catalysing the breakdown of plant polymers in the calf rumen.

Ferrer M, Ghazi A, Beloqui A, Vieites JM, López-Cortés N, Marín-Navarro J, Nechitaylo TY, Guazzaroni ME, Polaina J, Waliczek A, Chernikova TN, Reva ON, Golyshina OV, Golyshin PN.

PLoS One. 2012;7(6):e38134. doi: 10.1371/journal.pone.0038134. Epub 2012 Jun 25.

31.

A surface-based mass spectrometry method for screening glycosidase specificity in environmental samples.

Beloqui A, Sanchez-Ruiz A, Martin-Lomas M, Reichardt NC.

Chem Commun (Camb). 2012 Feb 4;48(11):1701-3. doi: 10.1039/c2cc16537f. Epub 2011 Dec 21.

PMID:
22189916
32.

Inter-conversion of catalytic abilities in a bifunctional carboxyl/feruloyl-esterase from earthworm gut metagenome.

Vieites JM, Ghazi A, Beloqui A, Polaina J, Andreu JM, Golyshina OV, Nechitaylo TY, Waliczek A, Yakimov MM, Golyshin PN, Ferrer M.

Microb Biotechnol. 2010 Jan;3(1):48-58. doi: 10.1111/j.1751-7915.2009.00135.x. Epub 2009 Jul 17.

33.

Retraction.

Beloqui A, Guazzaroni ME, Pazos F, Vieites JM, Godoy M, Golyshina OV, Chernikova TN, Waliczek A, Silva-Rocha R, Al-Ramahi Y, La Cono V, Mendez C, Salas JA, Solano R, Yakimov MM, Timmis KN, Golyshin PN, Ferrer M.

Science. 2010 Nov 12;330(6006):912. doi: 10.1126/science.330.6006.912-a. No abstract available.

PMID:
21071648
34.

Metagenomic era for biocatalyst identification.

Fernández-Arrojo L, Guazzaroni ME, López-Cortés N, Beloqui A, Ferrer M.

Curr Opin Biotechnol. 2010 Dec;21(6):725-33. doi: 10.1016/j.copbio.2010.09.006. Epub 2010 Oct 9. Review.

PMID:
20934867
35.

Screening metagenomic libraries for laccase activities.

Ferrer M, Beloqui A, Golyshin PN.

Methods Mol Biol. 2010;668:189-202. doi: 10.1007/978-1-60761-823-2_13.

PMID:
20830565
36.

Molecular methods to study complex microbial communities.

Vieites JM, Guazzaroni ME, Beloqui A, Golyshin PN, Ferrer M.

Methods Mol Biol. 2010;668:1-37. doi: 10.1007/978-1-60761-823-2_1.

PMID:
20830553
37.

Novel hybrid esterase-haloacid dehalogenase enzyme.

Beloqui A, Polaina J, Vieites JM, Reyes-Duarte D, Torres R, Golyshina OV, Chernikova TN, Waliczek A, Aharoni A, Yakimov MM, Timmis KN, Golyshin PN, Ferrer M.

Chembiochem. 2010 Sep 24;11(14):1975-8. doi: 10.1002/cbic.201000258. No abstract available.

PMID:
20715265
38.

Diversity of glycosyl hydrolases from cellulose-depleting communities enriched from casts of two earthworm species.

Beloqui A, Nechitaylo TY, López-Cortés N, Ghazi A, Guazzaroni ME, Polaina J, Strittmatter AW, Reva O, Waliczek A, Yakimov MM, Golyshina OV, Ferrer M, Golyshin PN.

Appl Environ Microbiol. 2010 Sep;76(17):5934-46. doi: 10.1128/AEM.00902-10. Epub 2010 Jul 9.

39.

Reactome array: forging a link between metabolome and genome.

Beloqui A, Guazzaroni ME, Pazos F, Vieites JM, Godoy M, Golyshina OV, Chernikova TN, Waliczek A, Silva-Rocha R, Al-Ramahi Y, La Cono V, Mendez C, Salas JA, Solano R, Yakimov MM, Timmis KN, Golyshin PN, Ferrer M.

Science. 2009 Oct 9;326(5950):252-7. doi: 10.1126/science.1174094. Retraction in: Beloqui A, Guazzaroni ME, Pazos F, Vieites JM, Godoy M, Golyshina OV, Chernikova TN, Waliczek A, Silva-Rocha R, Al-Ramahi Y, La Cono V, Mendez C, Salas JA, Solano R, Yakimov MM, Timmis KN, Golyshin PN, Ferrer M. Science. 2010 Nov 12;330(6006):912.

40.

Interplay of metagenomics and in vitro compartmentalization.

Ferrer M, Beloqui A, Vieites JM, Guazzaroni ME, Berger I, Aharoni A.

Microb Biotechnol. 2009 Jan;2(1):31-9. doi: 10.1111/j.1751-7915.2008.00057.x. Epub 2008 Oct 13. Review.

41.

Metagenomics approaches in systems microbiology.

Vieites JM, Guazzaroni ME, Beloqui A, Golyshin PN, Ferrer M.

FEMS Microbiol Rev. 2009 Jan;33(1):236-55. doi: 10.1111/j.1574-6976.2008.00152.x. Epub 2008 Nov 24. Review.

42.

Metagenomics for mining new genetic resources of microbial communities.

Ferrer M, Beloqui A, Timmis KN, Golyshin PN.

J Mol Microbiol Biotechnol. 2009;16(1-2):109-23. doi: 10.1159/000142898. Epub 2008 Oct 29. Review.

43.

A purple acidophilic di-ferric DNA ligase from Ferroplasma.

Ferrer M, Golyshina OV, Beloqui A, Böttger LH, Andreu JM, Polaina J, De Lacey AL, Trautwein AX, Timmis KN, Golyshin PN.

Proc Natl Acad Sci U S A. 2008 Jul 1;105(26):8878-83. doi: 10.1073/pnas.0800071105. Epub 2008 Jun 24.

44.

Recent trends in industrial microbiology.

Beloqui A, de María PD, Golyshin PN, Ferrer M.

Curr Opin Microbiol. 2008 Jun;11(3):240-8. doi: 10.1016/j.mib.2008.04.005. Epub 2008 Jun 12. Review.

PMID:
18554976
45.

Catalytic role of conserved HQGE motif in the CE6 carbohydrate esterase family.

López-Cortés N, Reyes-Duarte D, Beloqui A, Polaina J, Ghazi I, Golyshina OV, Ballesteros A, Golyshin PN, Ferrer M.

FEBS Lett. 2007 Oct 2;581(24):4657-62. Epub 2007 Sep 4.

46.

Mining enzymes from extreme environments.

Ferrer M, Golyshina O, Beloqui A, Golyshin PN.

Curr Opin Microbiol. 2007 Jun;10(3):207-14. Epub 2007 Jun 4. Review.

PMID:
17548239
47.

Biochemical and structural features of a novel cyclodextrinase from cow rumen metagenome.

Ferrer M, Beloqui A, Golyshina OV, Plou FJ, Neef A, Chernikova TN, Fernández-Arrojo L, Ghazi I, Ballesteros A, Elborough K, Timmis KN, Golyshin PN.

Biotechnol J. 2007 Feb;2(2):207-13.

PMID:
17238236
48.

The cellular machinery of Ferroplasma acidiphilum is iron-protein-dominated.

Ferrer M, Golyshina OV, Beloqui A, Golyshin PN, Timmis KN.

Nature. 2007 Jan 4;445(7123):91-4.

PMID:
17203061
49.

Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships.

Beloqui A, Pita M, Polaina J, Martínez-Arias A, Golyshina OV, Zumárraga M, Yakimov MM, García-Arellano H, Alcalde M, Fernández VM, Elborough K, Andreu JM, Ballesteros A, Plou FJ, Timmis KN, Ferrer M, Golyshin PN.

J Biol Chem. 2006 Aug 11;281(32):22933-42. Epub 2006 Jun 1.

50.

[Cohort of asbestos exposed workers. Navarre (Spain) 1999-2004].

Artieda L, Beloqui A, Lezaun M.

An Sist Sanit Navar. 2005 Sep-Dec;28(3):335-44. Spanish.

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