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Items: 42

1.

Age-related cardiopathies gene editing.

Song M, Belmonte JCI, Liu GH.

Aging (Albany NY). 2019 Mar 10;11(5):1327-1328. doi: 10.18632/aging.101853. No abstract available.

2.

Author Correction: Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.

Kang E, Wu J, Gutierrez NM, Koski A, Tippner-Hedges R, Agaronyan K, Platero-Luengo A, Martinez-Redondo P, Ma H, Lee Y, Hayama T, Van Dyken C, Wang X, Luo S, Ahmed R, Li Y, Ji D, Kayali R, Cinnioglu C, Olson S, Jensen J, Battaglia D, Lee D, Wu D, Huang T, Wolf DP, Temiakov D, Belmonte JCI, Amato P, Mitalipov S.

Nature. 2019 Mar;567(7747):E5-E9. doi: 10.1038/s41586-019-0876-1.

PMID:
30814738
3.

Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells.

Ling C, Liu Z, Song M, Zhang W, Wang S, Liu X, Ma S, Sun S, Fu L, Chu Q, Belmonte JCI, Wang Z, Qu J, Yuan Y, Liu GH.

Protein Cell. 2019 Apr;10(4):249-271. doi: 10.1007/s13238-019-0608-1. Epub 2019 Feb 18.

4.

Gene Editing in 3D Cultured Nephron Progenitor Cell Lines.

Li Z, Araoka T, Belmonte JCI.

Methods Mol Biol. 2019;1926:151-159. doi: 10.1007/978-1-4939-9021-4_13.

PMID:
30742270
5.

Implantation initiation of self-assembled embryo-like structures generated using three types of mouse blastocyst-derived stem cells.

Zhang S, Chen T, Chen N, Gao D, Shi B, Kong S, West RC, Yuan Y, Zhi M, Wei Q, Xiang J, Mu H, Yue L, Lei X, Wang X, Zhong L, Liang H, Cao S, Belmonte JCI, Wang H, Han J.

Nat Commun. 2019 Jan 30;10(1):496. doi: 10.1038/s41467-019-08378-9.

6.

Induced pluripotent stem cell-based modeling of mutant LRRK2-associated Parkinson's disease.

Weykopf B, Haupt S, Jungverdorben J, Flitsch LJ, Hebisch M, Liu GH, Suzuki K, Belmonte JCI, Peitz M, Blaess S, Till A, Brüstle O.

Eur J Neurosci. 2019 Feb;49(4):561-589. doi: 10.1111/ejn.14345. Review.

PMID:
30656775
7.

Ma et al. reply.

Ma H, Marti-Gutierrez N, Park SW, Wu J, Hayama T, Darby H, Van Dyken C, Li Y, Koski A, Liang D, Suzuki K, Gu Y, Gong J, Xu X, Ahmed R, Lee Y, Kang E, Ji D, Park AR, Kim D, Kim ST, Heitner SB, Battaglia D, Krieg SA, Lee DM, Wu DH, Wolf DP, Amato P, Kaul S, Belmonte JCI, Kim JS, Mitalipov S.

Nature. 2018 Aug;560(7717):E10-E23. doi: 10.1038/s41586-018-0381-y. No abstract available.

PMID:
30089923
8.

Adenine base editing to mimic or correct disease mutations in rodents.

Ren R, Belmonte JCI, Liu GH.

Protein Cell. 2018 Sep;9(9):752-753. doi: 10.1007/s13238-018-0570-3. No abstract available.

9.

Roadblocks in the Path of iPSC to the Clinic.

Garreta E, Sanchez S, Lajara J, Montserrat N, Belmonte JCI.

Curr Transplant Rep. 2018;5(1):14-18. doi: 10.1007/s40472-018-0177-x. Epub 2018 Feb 8. Review.

10.

Kidney organoids for disease modeling.

Garreta E, Montserrat N, Belmonte JCI.

Oncotarget. 2018 Feb 7;9(16):12552-12553. doi: 10.18632/oncotarget.24438. eCollection 2018 Feb 27. No abstract available.

11.

Differential stem cell aging kinetics in Hutchinson-Gilford progeria syndrome and Werner syndrome.

Wu Z, Zhang W, Song M, Wang W, Wei G, Li W, Lei J, Huang Y, Sang Y, Chan P, Chen C, Qu J, Suzuki K, Belmonte JCI, Liu GH.

Protein Cell. 2018 Apr;9(4):333-350. doi: 10.1007/s13238-018-0517-8. Epub 2018 Feb 23.

12.

LRRK2 functions as a scaffolding kinase of ASK1-mediated neuronal cell death.

Yoon JH, Mo JS, Kim MY, Ann EJ, Ahn JS, Jo EH, Lee HJ, Lee YC, Seol W, Yarmoluk SM, Gasser T, Kahle PJ, Liu GH, Belmonte JCI, Park HS.

Biochim Biophys Acta Mol Cell Res. 2017 Dec;1864(12):2356-2368. doi: 10.1016/j.bbamcr.2017.09.001. Epub 2017 Sep 6.

13.

CRISPR-Cas9 mediated one-step disabling of pancreatogenesis in pigs.

Wu J, Vilarino M, Suzuki K, Okamura D, Bogliotti YS, Park I, Rowe J, McNabb B, Ross PJ, Belmonte JCI.

Sci Rep. 2017 Sep 5;7(1):10487. doi: 10.1038/s41598-017-08596-5.

14.

Correction of a pathogenic gene mutation in human embryos.

Ma H, Marti-Gutierrez N, Park SW, Wu J, Lee Y, Suzuki K, Koski A, Ji D, Hayama T, Ahmed R, Darby H, Van Dyken C, Li Y, Kang E, Park AR, Kim D, Kim ST, Gong J, Gu Y, Xu X, Battaglia D, Krieg SA, Lee DM, Wu DH, Wolf DP, Heitner SB, Belmonte JCI, Amato P, Kim JS, Kaul S, Mitalipov S.

Nature. 2017 Aug 24;548(7668):413-419. doi: 10.1038/nature23305. Epub 2017 Aug 2.

PMID:
28783728
15.

Understanding the genetics behind complex human disease with large-scale iPSC collections.

Yamasaki AE, Panopoulos AD, Belmonte JCI.

Genome Biol. 2017 Jul 20;18(1):135. doi: 10.1186/s13059-017-1276-1.

16.

Integration of CpG-free DNA induces de novo methylation of CpG islands in pluripotent stem cells.

Takahashi Y, Wu J, Suzuki K, Martinez-Redondo P, Li M, Liao HK, Wu MZ, Hernández-Benítez R, Hishida T, Shokhirev MN, Esteban CR, Sancho-Martinez I, Belmonte JCI.

Science. 2017 May 5;356(6337):503-508. doi: 10.1126/science.aag3260.

17.

Analysis of transcription factors expressed at the anterior mouse limb bud.

Yokoyama S, Furukawa S, Kitada S, Mori M, Saito T, Kawakami K, Belmonte JCI, Kawakami Y, Ito Y, Sato T, Asahara H.

PLoS One. 2017 May 3;12(5):e0175673. doi: 10.1371/journal.pone.0175673. eCollection 2017.

18.

CRISPR/Cas9-mediated targeted gene correction in amyotrophic lateral sclerosis patient iPSCs.

Wang L, Yi F, Fu L, Yang J, Wang S, Wang Z, Suzuki K, Sun L, Xu X, Yu Y, Qiao J, Belmonte JCI, Yang Z, Yuan Y, Qu J, Liu GH.

Protein Cell. 2017 May;8(5):365-378. doi: 10.1007/s13238-017-0397-3. Epub 2017 Apr 11.

19.

Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency.

Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, Xu Y, Dong J, Wang C, Lai W, Zhu J, Xiong L, Zhu D, Li X, Yang W, Yamauchi T, Sugawara A, Li Z, Sun F, Li X, Li C, He A, Du Y, Wang T, Zhao C, Li H, Chi X, Zhang H, Liu Y, Li C, Duo S, Yin M, Shen H, Belmonte JCI, Deng H.

Cell. 2017 Apr 6;169(2):243-257.e25. doi: 10.1016/j.cell.2017.02.005.

20.

Ground rules of the pluripotency gene regulatory network.

Li M, Belmonte JC.

Nat Rev Genet. 2017 Mar;18(3):180-191. doi: 10.1038/nrg.2016.156. Epub 2017 Jan 3. Review.

PMID:
28045100
21.

Mitochondrial replacement in human oocytes carrying pathogenic mitochondrial DNA mutations.

Kang E, Wu J, Gutierrez NM, Koski A, Tippner-Hedges R, Agaronyan K, Platero-Luengo A, Martinez-Redondo P, Ma H, Lee Y, Hayama T, Van Dyken C, Wang X, Luo S, Ahmed R, Li Y, Ji D, Kayali R, Cinnioglu C, Olson S, Jensen J, Battaglia D, Lee D, Wu D, Huang T, Wolf DP, Temiakov D, Belmonte JC, Amato P, Mitalipov S.

Nature. 2016 Dec 8;540(7632):270-275. doi: 10.1038/nature20592. Epub 2016 Nov 30. Erratum in: Nature. 2019 Mar;567(7747):E5-E9.

PMID:
27919073
22.

Stem cells and interspecies chimaeras.

Wu J, Greely HT, Jaenisch R, Nakauchi H, Rossant J, Belmonte JC.

Nature. 2016 Dec 1;540(7631):51-59. doi: 10.1038/nature20573. Review.

PMID:
27905428
23.

In vivo genome editing via CRISPR/Cas9 mediated homology-independent targeted integration.

Suzuki K, Tsunekawa Y, Hernandez-Benitez R, Wu J, Zhu J, Kim EJ, Hatanaka F, Yamamoto M, Araoka T, Li Z, Kurita M, Hishida T, Li M, Aizawa E, Guo S, Chen S, Goebl A, Soligalla RD, Qu J, Jiang T, Fu X, Jafari M, Esteban CR, Berggren WT, Lajara J, Nuñez-Delicado E, Guillen P, Campistol JM, Matsuzaki F, Liu GH, Magistretti P, Zhang K, Callaway EM, Zhang K, Belmonte JC.

Nature. 2016 Dec 1;540(7631):144-149. doi: 10.1038/nature20565. Epub 2016 Nov 16.

24.

Systems biology analysis reveals role of MDM2 in diabetic nephropathy.

Saito R, Rocanin-Arjo A, You YH, Darshi M, Van Espen B, Miyamoto S, Pham J, Pu M, Romoli S, Natarajan L, Ju W, Kretzler M, Nelson R, Ono K, Thomasova D, Mulay SR, Ideker T, D'Agati V, Beyret E, Belmonte JCI, Anders HJ, Sharma K.

JCI Insight. 2016 Oct 20;1(17):e87877. doi: 10.1172/jci.insight.87877.

25.

Cellular Metabolism and Induced Pluripotency.

Wu J, Ocampo A, Belmonte JCI.

Cell. 2016 Sep 8;166(6):1371-1385. doi: 10.1016/j.cell.2016.08.008. Review.

26.

Anti-Aging Strategies Based on Cellular Reprogramming.

Ocampo A, Reddy P, Belmonte JCI.

Trends Mol Med. 2016 Aug;22(8):725-738. doi: 10.1016/j.molmed.2016.06.005. Epub 2016 Jul 14. Review.

PMID:
27426043
27.

The Molecular Harbingers of Early Mammalian Embryo Patterning.

Wu J, Belmonte JCI.

Cell. 2016 Mar 24;165(1):13-15. doi: 10.1016/j.cell.2016.03.005.

28.

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging.

Zhang W, Li J, Suzuki K, Qu J, Wang P, Zhou J, Liu X, Ren R, Xu X, Ocampo A, Yuan T, Yang J, Li Y, Shi L, Guan D, Pan H, Duan S, Ding Z, Li M, Yi F, Bai R, Wang Y, Chen C, Yang F, Li X, Wang Z, Aizawa E, Goebl A, Soligalla RD, Reddy P, Esteban CR, Tang F, Liu GH, Belmonte JC.

Science. 2015 Jun 5;348(6239):1160-3. doi: 10.1126/science.aaa1356. Epub 2015 Apr 30.

29.

Identification of novel long noncoding RNAs underlying vertebrate cardiovascular development.

Kurian L, Aguirre A, Sancho-Martinez I, Benner C, Hishida T, Nguyen TB, Reddy P, Nivet E, Krause MN, Nelles DA, Esteban CR, Campistol JM, Yeo GW, Belmonte JCI.

Circulation. 2015 Apr 7;131(14):1278-1290. doi: 10.1161/CIRCULATIONAHA.114.013303. Epub 2015 Mar 4.

30.

Conversion of human fibroblasts into monocyte-like progenitor cells.

Pulecio J, Nivet E, Sancho-Martinez I, Vitaloni M, Guenechea G, Xia Y, Kurian L, Dubova I, Bueren J, Laricchia-Robbio L, Belmonte JCI.

Stem Cells. 2014 Nov;32(11):2923-2938. doi: 10.1002/stem.1800.

31.

Modelling Fanconi anemia pathogenesis and therapeutics using integration-free patient-derived iPSCs.

Liu GH, Suzuki K, Li M, Qu J, Montserrat N, Tarantino C, Gu Y, Yi F, Xu X, Zhang W, Ruiz S, Plongthongkum N, Zhang K, Masuda S, Nivet E, Tsunekawa Y, Soligalla RD, Goebl A, Aizawa E, Kim NY, Kim J, Dubova I, Li Y, Ren R, Benner C, Del Sol A, Bueren J, Trujillo JP, Surralles J, Cappelli E, Dufour C, Esteban CR, Belmonte JCI.

Nat Commun. 2014 Jul 7;5:4330. doi: 10.1038/ncomms5330.

32.

New strategies in kidney regeneration and tissue engineering.

Uzarski JS, Xia Y, Belmonte JC, Wertheim JA.

Curr Opin Nephrol Hypertens. 2014 Jul;23(4):399-405. doi: 10.1097/01.mnh.0000447019.66970.ea. Review.

PMID:
24848937
33.

Global DNA methylation and transcriptional analyses of human ESC-derived cardiomyocytes.

Gu Y, Liu GH, Plongthongkum N, Benner C, Yi F, Qu J, Suzuki K, Yang J, Zhang W, Li M, Montserrat N, Crespo I, Del Sol A, Esteban CR, Zhang K, Belmonte JC.

Protein Cell. 2013 Aug 27. [Epub ahead of print]

PMID:
23982742
34.

Switching cell fate, ncRNAs coming to play.

Guan D, Zhang W, Zhang W, Liu GH, Belmonte JC.

Cell Death Dis. 2013 Jan 17;4:e464. doi: 10.1038/cddis.2012.196. Review.

35.

New march towards the regeneration of sensation and cognition: hear more, see more and learn more.

Zhang K, Yi F, Liu GH, Belmonte JC.

J Mol Cell Biol. 2013 Apr;5(2):151-3. doi: 10.1093/jmcb/mjs060. Epub 2012 Dec 6. Review.

PMID:
23220740
36.

Establishment of hepatic and neural differentiation platforms of Wilson's disease specific induced pluripotent stem cells.

Yi F, Qu J, Li M, Suzuki K, Kim NY, Liu GH, Belmonte JC.

Protein Cell. 2012 Nov;3(11):855-63. doi: 10.1007/s13238-012-2064-z. Epub 2012 Jul 18.

37.

Cardiosphere-derived cells for heart regeneration.

Masuda S, Montserrat N, Okamura D, Suzuki K, Belmonte JCI.

Lancet. 2012 Jun 30;379(9835):2425-2426. doi: 10.1016/S0140-6736(12)61062-9. No abstract available. Erratum in: Lancet. 2012 Aug 25;380(9843):730. Monserrat, Nuria [corrected to Montserrat, Nuria].

PMID:
22748584
38.

Induced pluripotent stem cells in clinical hematology: potentials, progress, and remaining obstacles.

Panopoulos AD, Belmonte JC.

Curr Opin Hematol. 2012 Jul;19(4):256-60. doi: 10.1097/MOH.0b013e328353c78f. Review.

39.

Increased dosage of tumor suppressors limits the tumorigenicity of iPS cells without affecting their pluripotency.

Menendez S, Camus S, Herreria A, Paramonov I, Morera LB, Collado M, Pekarik V, Maceda I, Edel M, Consiglio A, Sanchez A, Li H, Serrano M, Belmonte JC.

Aging Cell. 2012 Feb;11(1):41-50. doi: 10.1111/j.1474-9726.2011.00754.x. Epub 2011 Nov 10.

40.

Embryonic stem cell-like cells derived from adult human testis.

Mizrak SC, Chikhovskaya JV, Sadri-Ardekani H, van Daalen S, Korver CM, Hovingh SE, Roepers-Gajadien HL, Raya A, Fluiter K, de Reijke TM, de la Rosette JJ, Knegt AC, Belmonte JC, van der Veen F, de Rooij DG, Repping S, van Pelt AM.

Hum Reprod. 2010 Jan;25(1):158-67. doi: 10.1093/humrep/dep354. Epub 2009 Oct 8.

PMID:
19815622
41.

Blockade of Cripto binding to cell surface GRP78 inhibits oncogenic Cripto signaling via MAPK/PI3K and Smad2/3 pathways.

Kelber JA, Panopoulos AD, Shani G, Booker EC, Belmonte JC, Vale WW, Gray PC.

Oncogene. 2009 Jun 18;28(24):2324-36. doi: 10.1038/onc.2009.97. Epub 2009 May 4.

42.

Multiple left-right asymmetry defects in Shh(-/-) mutant mice unveil a convergence of the shh and retinoic acid pathways in the control of Lefty-1.

Tsukui T, Capdevila J, Tamura K, Ruiz-Lozano P, Rodriguez-Esteban C, Yonei-Tamura S, Magallón J, Chandraratna RA, Chien K, Blumberg B, Evans RM, Belmonte JC.

Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11376-81.

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