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Items: 1 to 50 of 176

1.

Influence of CYP450 Enzymes, CES1, PON1, ABCB1, and P2RY12 Polymorphisms on Clopidogrel Response in Patients Subjected to a Percutaneous Neurointervention.

Saiz-Rodríguez M, Belmonte C, Caniego JL, Koller D, Zubiaur P, Bárcena E, Romero-Palacián D, Eugene AR, Ochoa D, Abad-Santos F.

Clin Ther. 2019 Jun;41(6):1199-1212.e2. doi: 10.1016/j.clinthera.2019.04.037. Epub 2019 May 23.

PMID:
31128980
2.

Polymorphisms in CYP1A2, CYP2C9 and ABCB1 affect agomelatine pharmacokinetics.

Saiz-Rodríguez M, Ochoa D, Belmonte C, Román M, Vieira de Lara D, Zubiaur P, Koller D, Mejía G, Abad-Santos F.

J Psychopharmacol. 2019 Apr;33(4):522-531. doi: 10.1177/0269881119827959. Epub 2019 Feb 21.

PMID:
30789308
3.

CYP2C19 Ultrarapid Phenotype as a Risk Predictor of Subsequent Events During Clopidogrel Treatment in Patients Undergoing a Percutaneous Neurointervention.

Saiz-Rodríguez M, Belmonte C, Abad-Santos F.

Clin Pharmacol Ther. 2019 May;105(5):1074-1075. doi: 10.1002/cpt.1300. Epub 2019 Jan 16. No abstract available.

PMID:
30652301
4.

The Immunosuppressant Macrolide Tacrolimus Activates Cold-Sensing TRPM8 Channels.

Arcas JM, González A, Gers-Barlag K, González-González O, Bech F, Demirkhanyan L, Zakharian E, Belmonte C, Gomis A, Viana F.

J Neurosci. 2019 Feb 6;39(6):949-969. doi: 10.1523/JNEUROSCI.1726-18.2018. Epub 2018 Dec 13.

PMID:
30545944
5.

Influence of thiopurine S-methyltransferase polymorphisms in mercaptopurine pharmacokinetics in healthy volunteers.

Saiz-Rodríguez M, Ochoa D, Belmonte C, Román M, Martínez-Ingelmo C, Ortega-Ruíz L, Sarmiento-Iglesias C, Herrador C, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2019 Apr;124(4):449-455. doi: 10.1111/bcpt.13153. Epub 2018 Nov 15.

PMID:
30346660
6.

Polymorphisms associated with fentanyl pharmacokinetics, pharmacodynamics and adverse effects.

Saiz-Rodríguez M, Ochoa D, Herrador C, Belmonte C, Román M, Alday E, Koller D, Zubiaur P, Mejía G, Hernández-Martínez M, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2019 Mar;124(3):321-329. doi: 10.1111/bcpt.13141. Epub 2018 Oct 30.

PMID:
30281924
7.

Effects of aripiprazole on pupillometric parameters related to pharmacokinetics and pharmacogenetics after single oral administration to healthy subjects.

Koller D, Belmonte C, Lubomirov R, Saiz-Rodríguez M, Zubiaur P, Román M, Ochoa D, Carcas A, Wojnicz A, Abad-Santos F.

J Psychopharmacol. 2018 Nov;32(11):1212-1222. doi: 10.1177/0269881118798605. Epub 2018 Sep 25.

PMID:
30251598
8.

Functional and Morphologic Alterations in Mechanical, Polymodal, and Cold Sensory Nerve Fibers of the Cornea Following Photorefractive Keratectomy.

Bech F, González-González O, Artime E, Serrano J, Alcalde I, Gallar J, Merayo-Lloves J, Belmonte C.

Invest Ophthalmol Vis Sci. 2018 May 1;59(6):2281-2292. doi: 10.1167/iovs.18-24007.

PMID:
29847633
9.

Effect of ABCB1 C3435T Polymorphism on Pharmacokinetics of Antipsychotics and Antidepressants.

Saiz-Rodríguez M, Belmonte C, Román M, Ochoa D, Jiang-Zheng C, Koller D, Mejía G, Zubiaur P, Wojnicz A, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2018 Oct;123(4):474-485. doi: 10.1111/bcpt.13031. Epub 2018 Jun 13.

PMID:
29723928
10.

Morphological and functional changes in TRPM8-expressing corneal cold thermoreceptor neurons during aging and their impact on tearing in mice.

Alcalde I, Íñigo-Portugués A, González-González O, Almaraz L, Artime E, Morenilla-Palao C, Gallar J, Viana F, Merayo-Lloves J, Belmonte C.

J Comp Neurol. 2018 Aug 1;526(11):1859-1874. doi: 10.1002/cne.24454. Epub 2018 May 2.

PMID:
29664111
11.

Influence of CYP2C19 Phenotype on the Effect of Clopidogrel in Patients Undergoing a Percutaneous Neurointervention Procedure.

Saiz-Rodríguez M, Romero-Palacián D, Villalobos-Vilda C, Caniego JL, Belmonte C, Koller D, Bárcena E, Talegón M, Abad-Santos F.

Clin Pharmacol Ther. 2019 Mar;105(3):661-671. doi: 10.1002/cpt.1067. Epub 2018 Apr 17.

PMID:
29536505
12.

Robert F. Schmidt Ph.D., Prof. Dr. med. D. Sc. h.c. 1932-2017 Facets of a life for science.

Belmonte C, Birbaumer N, Carmody J, Jänig W, Messlinger K, Sato Y, Uchida S, Handwerker HO.

Eur J Pain. 2018 Feb;22(2):207-213. doi: 10.1002/ejp.1170. No abstract available.

PMID:
29350483
13.

Influence of CYP2D6, CYP3A4, CYP3A5 and ABCB1 Polymorphisms on Pharmacokinetics and Safety of Aripiprazole in Healthy Volunteers.

Belmonte C, Ochoa D, Román M, Saiz-Rodríguez M, Wojnicz A, Gómez-Sánchez CI, Martín-Vílchez S, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2018 Jun;122(6):596-605. doi: 10.1111/bcpt.12960. Epub 2018 Feb 22.

14.

Effective phospholipids removing microelution-solid phase extraction LC-MS/MS method for simultaneous plasma quantification of aripiprazole and dehydro-aripiprazole: Application to human pharmacokinetic studies.

Wojnicz A, Belmonte C, Koller D, Ruiz-Nuño A, Román M, Ochoa D, Abad-Santos F.

J Pharm Biomed Anal. 2018 Mar 20;151:116-125. doi: 10.1016/j.jpba.2017.12.049. Epub 2017 Dec 28.

PMID:
29324280
15.

Joint nociceptor nerve activity and pain in an animal model of acute gout and its modulation by intra-articular hyaluronan.

Marcotti A, Miralles A, Dominguez E, Pascual E, Gomis A, Belmonte C, de la Peña E.

Pain. 2018 Apr;159(4):739-748. doi: 10.1097/j.pain.0000000000001137.

16.

Polymorphisms associated with adalimumab and infliximab response in moderate-to-severe plaque psoriasis.

Ovejero-Benito MC, Prieto-Pérez R, Llamas-Velasco M, Muñoz-Aceituno E, Reolid A, Saiz-Rodríguez M, Belmonte C, Román M, Ochoa D, Talegón M, Cabaleiro T, Daudén E, Abad-Santos F.

Pharmacogenomics. 2018 Jan;19(1):7-16. doi: 10.2217/pgs-2017-0143. Epub 2017 Dec 1.

PMID:
29192552
17.

Inhibitory Effect of Amitriptyline on the Impulse Activity of Cold Thermoreceptor Terminals of Intact and Tear-Deficient Guinea Pig Corneas.

Masuoka T, Gallar J, Belmonte C.

J Ocul Pharmacol Ther. 2018 Jan/Feb;34(1-2):195-203. doi: 10.1089/jop.2017.0066. Epub 2017 Nov 29.

PMID:
29185841
18.

Building Bridges through Science.

Lissek T, Adams M, Adelman J, Ahissar E, Akaaboune M, Akil H, al'Absi M, Arain F, Arango-Lasprilla JC, Atasoy D, Avila J, Badawi A, Bading H, Baig AM, Baleriola J, Belmonte C, Bertocchi I, Betz H, Blakemore C, Blanke O, Boehm-Sturm P, Bonhoeffer T, Bonifazi P, Brose N, Campolongo P, Celikel T, Chang CC, Chang TY, Citri A, Cline HT, Cortes JM, Cullen K, Dean K, Delgado-Garcia JM, Desroches M, Disterhoft JF, Dowling JE, Draguhn A, El-Khamisy SF, El Manira A, Enam SA, Encinas JM, Erramuzpe A, Esteban JA, Fariñas I, Fischer E, Fukunaga I, Gabilondo I, Ganten D, Gidon A, Gomez-Esteban JC, Greengard P, Grinevich V, Gruart A, Guillemin R, Hariri AR, Hassan B, Häusser M, Hayashi Y, Hussain NK, Jabbar AA, Jaber M, Jahn R, Janahi EM, Kabbaj M, Kettenmann H, Kindt M, Knafo S, Köhr G, Komai S, Krugers H, Kuhn B, Ghazal NL, Larkum ME, London M, Lutz B, Matute C, Martinez-Millan L, Maroun M, McGaugh J, Moustafa AA, Nasim A, Nave KA, Neher E, Nikolich K, Outeiro T, Palmer LM, Penagarikano O, Perez-Otano I, Pfaff DW, Poucet B, Rahman AU, Ramos-Cabrer P, Rashidy-Pour A, Roberts RJ, Rodrigues S, Sanes JR, Schaefer AT, Segal M, Segev I, Shafqat S, Siddiqui NA, Soreq H, Soriano-García E, Spanagel R, Sprengel R, Stuart G, Südhof TC, Tønnesen J, Treviño M, Uthman BM, Venter JC, Verkhratsky A, Weiss C, Wiesel TN, Yaksi E, Yizhar O, Young LJ, Young P, Zawia NH, Zugaza JL, Hasan MT.

Neuron. 2017 Nov 15;96(4):730-735. doi: 10.1016/j.neuron.2017.09.028.

19.

Effect of Polymorphisms on the Pharmacokinetics, Pharmacodynamics and Safety of Sertraline in Healthy Volunteers.

Saiz-Rodríguez M, Belmonte C, Román M, Ochoa D, Koller D, Talegón M, Ovejero-Benito MC, López-Rodríguez R, Cabaleiro T, Abad-Santos F.

Basic Clin Pharmacol Toxicol. 2018 May;122(5):501-511. doi: 10.1111/bcpt.12938. Epub 2017 Dec 13.

20.

Pharmacogenetics of trazodone in healthy volunteers: association with pharmacokinetics, pharmacodynamics and safety.

Saiz-Rodríguez M, Belmonte C, Derqui-Fernández N, Cabaleiro T, Román M, Ochoa D, Talegón M, Ovejero-Benito MC, Abad-Santos F.

Pharmacogenomics. 2017 Nov;18(16):1491-1502. doi: 10.2217/pgs-2017-0116. Epub 2017 Oct 24.

PMID:
29061081
21.

TFOS DEWS II Report Executive Summary.

Craig JP, Nelson JD, Azar DT, Belmonte C, Bron AJ, Chauhan SK, de Paiva CS, Gomes JAP, Hammitt KM, Jones L, Nichols JJ, Nichols KK, Novack GD, Stapleton FJ, Willcox MDP, Wolffsohn JS, Sullivan DA.

Ocul Surf. 2017 Oct;15(4):802-812. doi: 10.1016/j.jtos.2017.08.003. Epub 2017 Aug 8. Review.

PMID:
28797892
22.

TFOS DEWS II pain and sensation report.

Belmonte C, Nichols JJ, Cox SM, Brock JA, Begley CG, Bereiter DA, Dartt DA, Galor A, Hamrah P, Ivanusic JJ, Jacobs DS, McNamara NA, Rosenblatt MI, Stapleton F, Wolffsohn JS.

Ocul Surf. 2017 Jul;15(3):404-437. doi: 10.1016/j.jtos.2017.05.002. Epub 2017 Jul 20. Review.

23.

TFOS DEWS II Introduction.

Nelson JD, Craig JP, Akpek EK, Azar DT, Belmonte C, Bron AJ, Clayton JA, Dogru M, Dua HS, Foulks GN, Gomes JAP, Hammitt KM, Holopainen J, Jones L, Joo CK, Liu Z, Nichols JJ, Nichols KK, Novack GD, Sangwan V, Stapleton F, Tomlinson A, Tsubota K, Willcox MDP, Wolffsohn JS, Sullivan DA.

Ocul Surf. 2017 Jul;15(3):269-275. doi: 10.1016/j.jtos.2017.05.005. Epub 2017 Jul 20. Review. No abstract available.

PMID:
28736334
24.

Polymorphisms associated with etanercept response in moderate-to-severe plaque psoriasis.

Ovejero-Benito MC, Prieto-Pérez R, Llamas-Velasco M, Belmonte C, Cabaleiro T, Román M, Ochoa D, Talegón M, Saiz-Rodríguez M, Daudén E, Abad-Santos F.

Pharmacogenomics. 2017 May;18(7):631-638. doi: 10.2217/pgs-2017-0014. Epub 2017 May 4.

PMID:
28470127
25.

Functional Properties of Sensory Nerve Terminals of the Mouse Cornea.

González-González O, Bech F, Gallar J, Merayo-Lloves J, Belmonte C.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):404-415. doi: 10.1167/iovs.16-20033.

PMID:
28118665
26.

Evaluation of the Relationship Between Pharmacokinetics and the Safety of Aripiprazole and Its Cardiovascular Effects in Healthy Volunteers.

Belmonte C, Ochoa D, Román M, Cabaleiro T, Talegón M, Sánchez-Rojas SD, Abad-Santos F.

J Clin Psychopharmacol. 2016 Dec;36(6):608-614.

27.

Confocal Microscopy of Corneal Nerves-a Limited but Still Useful Technique to Evaluate Peripheral Neuropathies.

Tervo T, Holopainen J, Belmonte C.

JAMA Ophthalmol. 2016 Sep 1;134(9):990-1. doi: 10.1001/jamaophthalmol.2016.2178. No abstract available.

PMID:
27368077
28.

Lacosamide diminishes dryness-induced hyperexcitability of corneal cold sensitive nerve terminals.

Kovács I, Dienes L, Perényi K, Quirce S, Luna C, Mizerska K, Acosta MC, Belmonte C, Gallar J.

Eur J Pharmacol. 2016 Sep 15;787:2-8. doi: 10.1016/j.ejphar.2016.05.044. Epub 2016 Jun 3.

PMID:
27263827
29.

Report of the Inaugural Meeting of the TFOS i(2) = initiating innovation Series: Targeting the Unmet Need for Dry Eye Treatment.

Chao W, Belmonte C, Benitez Del Castillo JM, Bron AJ, Dua HS, Nichols KK, Novack GD, Schrader S, Willcox MD, Wolffsohn JS, Sullivan DA.

Ocul Surf. 2016 Apr;14(2):264-316. doi: 10.1016/j.jtos.2015.11.003. Epub 2016 Jan 14.

PMID:
26774910
30.

Abnormal activity of corneal cold thermoreceptors underlies the unpleasant sensations in dry eye disease.

Kovács I, Luna C, Quirce S, Mizerska K, Callejo G, Riestra A, Fernández-Sánchez L, Meseguer VM, Cuenca N, Merayo-Lloves J, Acosta MC, Gasull X, Belmonte C, Gallar J.

Pain. 2016 Feb;157(2):399-417. doi: 10.1097/j.pain.0000000000000455.

31.

TRPV1 channel modulation by hyaluronan reduces pain.

de la Peña E, Gomis A, Ferrer-Montiel A, Belmonte C.

Channels (Austin). 2016;10(2):81-2. doi: 10.1080/19336950.2015.1109300. Epub 2015 Oct 30. No abstract available.

32.

Hyaluronan modulates TRPV1 channel opening, reducing peripheral nociceptor activity and pain.

Caires R, Luis E, Taberner FJ, Fernandez-Ballester G, Ferrer-Montiel A, Balazs EA, Gomis A, Belmonte C, de la Peña E.

Nat Commun. 2015 Aug 27;6:8095. doi: 10.1038/ncomms9095.

33.

Optimization of electrically tunable VCSEL with intracavity nematic liquid crystal.

Belmonte C, Frasunkiewicz L, Czyszanowski T, Thienpont H, Beeckman J, Neyts K, Panajotov K.

Opt Express. 2015 Jun 15;23(12):15706-15. doi: 10.1364/OE.23.015706.

PMID:
26193549
34.

What Causes Eye Pain?

Belmonte C, Acosta MC, Merayo-Lloves J, Gallar J.

Curr Ophthalmol Rep. 2015;3(2):111-121.

35.

TRPM8 is a neuronal osmosensor that regulates eye blinking in mice.

Quallo T, Vastani N, Horridge E, Gentry C, Parra A, Moss S, Viana F, Belmonte C, Andersson DA, Bevan S.

Nat Commun. 2015 May 22;6:7150. doi: 10.1038/ncomms8150.

36.

Preclinical pharmacology, ocular tolerability and ocular hypotensive efficacy of a novel non-peptide bradykinin mimetic small molecule.

Sharif NA, Li L, Katoli P, Xu S, Veltman J, Li B, Scott D, Wax M, Gallar J, Acosta C, Belmonte C.

Exp Eye Res. 2014 Nov;128:170-80. doi: 10.1016/j.exer.2014.10.008. Epub 2014 Oct 11.

PMID:
25307520
37.

Corneal sensory nerve activity in an experimental model of UV keratitis.

Acosta MC, Luna C, Quirce S, Belmonte C, Gallar J.

Invest Ophthalmol Vis Sci. 2014 May 1;55(6):3403-12. doi: 10.1167/iovs.13-13774.

PMID:
24787567
38.

Tear fluid hyperosmolality increases nerve impulse activity of cold thermoreceptor endings of the cornea.

Parra A, Gonzalez-Gonzalez O, Gallar J, Belmonte C.

Pain. 2014 Aug;155(8):1481-91. doi: 10.1016/j.pain.2014.04.025. Epub 2014 Apr 28.

39.

Expression of cholecystokinin, gastrin, and their receptors in the mouse cornea.

Gonzalez-Coto AF, Alonso-Ron C, Alcalde I, Gallar J, Meana Á, Merayo-Lloves J, Belmonte C.

Invest Ophthalmol Vis Sci. 2014 Mar 28;55(3):1965-75. doi: 10.1167/iovs.13-12068.

PMID:
24576871
40.

TRPA1 channels mediate acute neurogenic inflammation and pain produced by bacterial endotoxins.

Meseguer V, Alpizar YA, Luis E, Tajada S, Denlinger B, Fajardo O, Manenschijn JA, Fernández-Peña C, Talavera A, Kichko T, Navia B, Sánchez A, Señarís R, Reeh P, Pérez-García MT, López-López JR, Voets T, Belmonte C, Talavera K, Viana F.

Nat Commun. 2014;5:3125. doi: 10.1038/ncomms4125.

41.

Amplified cold transduction in native nociceptors by M-channel inhibition.

Vetter I, Hein A, Sattler S, Hessler S, Touska F, Bressan E, Parra A, Hager U, Leffler A, Boukalova S, Nissen M, Lewis RJ, Belmonte C, Alzheimer C, Huth T, Vlachova V, Reeh PW, Zimmermann K.

J Neurosci. 2013 Oct 16;33(42):16627-41. doi: 10.1523/JNEUROSCI.1473-13.2013.

42.

The TFOS International Workshop on Contact Lens Discomfort: report of the subcommittee on neurobiology.

Stapleton F, Marfurt C, Golebiowski B, Rosenblatt M, Bereiter D, Begley C, Dartt D, Gallar J, Belmonte C, Hamrah P, Willcox M; TFOS International Workshop on Contact Lens Discomfort.

Invest Ophthalmol Vis Sci. 2013 Oct 18;54(11):TFOS71-97. doi: 10.1167/iovs.13-13226.

43.

The TFOS International Workshop on Contact Lens Discomfort: executive summary.

Nichols JJ, Willcox MD, Bron AJ, Belmonte C, Ciolino JB, Craig JP, Dogru M, Foulks GN, Jones L, Nelson JD, Nichols KK, Purslow C, Schaumberg DA, Stapleton F, Sullivan DA; members of the TFOS International Workshop on Contact Lens Discomfort.

Invest Ophthalmol Vis Sci. 2013 Oct 18;54(11):TFOS7-TFOS13. doi: 10.1167/iovs.13-13212. No abstract available.

44.

Blockade of nociceptive sensory afferent activity of the rat knee joint by the bradykinin B2 receptor antagonist fasitibant.

Gomis A, Meini S, Miralles A, Valenti C, Giuliani S, Belmonte C, Maggi CA.

Osteoarthritis Cartilage. 2013 Sep;21(9):1346-54. doi: 10.1016/j.joca.2013.03.013.

45.

Changes in sensory activity of ocular surface sensory nerves during allergic keratoconjunctivitis.

Acosta MC, Luna C, Quirce S, Belmonte C, Gallar J.

Pain. 2013 Nov;154(11):2353-62. doi: 10.1016/j.pain.2013.07.012. Epub 2013 Jul 16.

PMID:
23867735
46.

The influence of cold temperature on cellular excitability of hippocampal networks.

de la Peña E, Mälkiä A, Vara H, Caires R, Ballesta JJ, Belmonte C, Viana F.

PLoS One. 2012;7(12):e52475. doi: 10.1371/journal.pone.0052475. Epub 2012 Dec 31.

47.

Role of Ih in the firing pattern of mammalian cold thermoreceptor endings.

Orio P, Parra A, Madrid R, González O, Belmonte C, Viana F.

J Neurophysiol. 2012 Dec;108(11):3009-23. doi: 10.1152/jn.01033.2011. Epub 2012 Sep 5.

48.

Direct inhibition of the cold-activated TRPM8 ion channel by Gαq.

Zhang X, Mak S, Li L, Parra A, Denlinger B, Belmonte C, McNaughton PA.

Nat Cell Biol. 2012 Aug;14(8):851-8. doi: 10.1038/ncb2529. Epub 2012 Jul 1.

49.

Effects of presentation mode on veridical and false memory in individuals with intellectual disability.

Carlin M, Toglia MP, Belmonte C, DiMeglio C.

Am J Intellect Dev Disabil. 2012 May;117(3):183-93. doi: 10.1352/1944-7558-117.3.183.

PMID:
22716261
50.

N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons.

Pertusa M, Madrid R, Morenilla-Palao C, Belmonte C, Viana F.

J Biol Chem. 2012 May 25;287(22):18218-29. doi: 10.1074/jbc.M111.312645. Epub 2012 Apr 5.

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