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Items: 25


Bioactivation of napabucasin triggers reactive oxygen species-mediated cancer cell death.

Froeling FEM, Mosur Swamynathan M, Deschênes A, Chio IIC, Brosnan E, Yao MA, Alagesan P, Lucito MS, Li J, Chang AY, Trotman LC, Belleau P, Park Y, Rogoff HA, Watson JD, Tuveson DA.

Clin Cancer Res. 2019 Sep 16. pii: clincanres.0302.2019. doi: 10.1158/1078-0432.CCR-19-0302. [Epub ahead of print]


Cross-Species Single-Cell Analysis of Pancreatic Ductal Adenocarcinoma Reveals Antigen-Presenting Cancer-Associated Fibroblasts.

Elyada E, Bolisetty M, Laise P, Flynn WF, Courtois ET, Burkhart RA, Teinor JA, Belleau P, Biffi G, Lucito MS, Sivajothi S, Armstrong TD, Engle DD, Yu KH, Hao Y, Wolfgang CL, Park Y, Preall J, Jaffee EM, Califano A, Robson P, Tuveson DA.

Cancer Discov. 2019 Aug;9(8):1102-1123. doi: 10.1158/2159-8290.CD-19-0094. Epub 2019 Jun 13.


A type 2 diabetes disease module with a high collective influence for Cdk2 and PTPLAD1 is localized in endosomes.

Boutchueng-Djidjou M, Belleau P, Bilodeau N, Fortier S, Bourassa S, Droit A, Elowe S, Faure RL.

PLoS One. 2018 Oct 9;13(10):e0205180. doi: 10.1371/journal.pone.0205180. eCollection 2018.


Organoid Profiling Identifies Common Responders to Chemotherapy in Pancreatic Cancer.

Tiriac H, Belleau P, Engle DD, Plenker D, Deschênes A, Somerville TDD, Froeling FEM, Burkhart RA, Denroche RE, Jang GH, Miyabayashi K, Young CM, Patel H, Ma M, LaComb JF, Palmaira RLD, Javed AA, Huynh JC, Johnson M, Arora K, Robine N, Shah M, Sanghvi R, Goetz AB, Lowder CY, Martello L, Driehuis E, LeComte N, Askan G, Iacobuzio-Donahue CA, Clevers H, Wood LD, Hruban RH, Thompson E, Aguirre AJ, Wolpin BM, Sasson A, Kim J, Wu M, Bucobo JC, Allen P, Sejpal DV, Nealon W, Sullivan JD, Winter JM, Gimotty PA, Grem JL, DiMaio DJ, Buscaglia JM, Grandgenett PM, Brody JR, Hollingsworth MA, O'Kane GM, Notta F, Kim E, Crawford JM, Devoe C, Ocean A, Wolfgang CL, Yu KH, Li E, Vakoc CR, Hubert B, Fischer SE, Wilson JM, Moffitt R, Knox J, Krasnitz A, Gallinger S, Tuveson DA.

Cancer Discov. 2018 Sep;8(9):1112-1129. doi: 10.1158/2159-8290.CD-18-0349. Epub 2018 May 31.


Inferring and modeling inheritance of differentially methylated changes across multiple generations.

Belleau P, Deschênes A, Scott-Boyer MP, Lambrot R, Dalvai M, Kimmins S, Bailey J, Droit A.

Nucleic Acids Res. 2018 Aug 21;46(14):7466. doi: 10.1093/nar/gky477. No abstract available.


Inferring and modeling inheritance of differentially methylated changes across multiple generations.

Belleau P, Deschênes A, Scott-Boyer MP, Lambrot R, Dalvai M, Kimmins S, Bailey J, Droit A.

Nucleic Acids Res. 2018 Aug 21;46(14):e85. doi: 10.1093/nar/gky362. Erratum in: Nucleic Acids Res. 2018 Aug 21;46(14):7466.


metagene Profiles Analyses Reveal Regulatory Element's Factor-Specific Recruitment Patterns.

Joly Beauparlant C, Lamaze FC, Deschênes A, Samb R, Lemaçon A, Belleau P, Bilodeau S, Droit A.

PLoS Comput Biol. 2016 Aug 18;12(8):e1004751. doi: 10.1371/journal.pcbi.1004751. eCollection 2016 Aug.


Using informative Multinomial-Dirichlet prior in a t-mixture with reversible jump estimation of nucleosome positions for genome-wide profiling.

Samb R, Khadraoui K, Belleau P, Deschênes A, Lakhal-Chaieb L, Droit A.

Stat Appl Genet Mol Biol. 2015 Dec;14(6):517-32. doi: 10.1515/sagmb-2014-0098.


Germline copy number variation in the YTHDC2 gene: does it have a role in finding a novel potential molecular target involved in pancreatic adenocarcinoma susceptibility?

Fanale D, Iovanna JL, Calvo EL, Berthezene P, Belleau P, Dagorn JC, Bronte G, Cicero G, Bazan V, Rolfo C, Santini D, Russo A.

Expert Opin Ther Targets. 2014 Aug;18(8):841-50. doi: 10.1517/14728222.2014.920324. Epub 2014 May 16.


Analysis of germline gene copy number variants of patients with sporadic pancreatic adenocarcinoma reveals specific variations.

Fanale D, Iovanna JL, Calvo EL, Berthezene P, Belleau P, Dagorn JC, Ancona C, Catania G, D'Alia P, Galvano A, Gulotta E, Lo Dico S, Passiglia F, Bronte G, Midiri M, Lo Re G, Cicero G, Bazan V, Russo A.

Oncology. 2013;85(5):306-11. doi: 10.1159/000354737. Epub 2013 Nov 9.


Analysis of ZNF350/ZBRK1 promoter variants and breast cancer susceptibility in non-BRCA1/2 French Canadian breast cancer families.

Plourde KV, Labrie Y, Desjardins S, Belleau P, Ouellette G, Durocher F; INHERIT BRCAs.

J Hum Genet. 2013 Feb;58(2):59-66. doi: 10.1038/jhg.2012.127. Epub 2012 Nov 15.


Polymorphic variations in the FANCA gene in high-risk non-BRCA1/2 breast cancer individuals from the French Canadian population.

Litim N, Labrie Y, Desjardins S, Ouellette G, Plourde K, Belleau P; INHERIT BRCAs, Durocher F.

Mol Oncol. 2013 Feb;7(1):85-100. doi: 10.1016/j.molonc.2012.08.002. Epub 2012 Sep 11.


Specific transcriptional response of four blockers of estrogen receptors on estradiol-modulated genes in the mouse mammary gland.

Calvo E, Luu-The V, Belleau P, Martel C, Labrie F.

Breast Cancer Res Treat. 2012 Jul;134(2):625-47. doi: 10.1007/s10549-012-2104-7. Epub 2012 Jun 8.


PITX2 is involved in stress response in cultured human trabecular meshwork cells through regulation of SLC13A3.

Strungaru MH, Footz T, Liu Y, Berry FB, Belleau P, Semina EV, Raymond V, Walter MA.

Invest Ophthalmol Vis Sci. 2011 Sep 29;52(10):7625-33. doi: 10.1167/iovs.10-6967.


Fine temporal analysis of DHT transcriptional modulation of the ATM/Gadd45g signaling pathways in the mouse uterus.

Ivanga M, Labrie Y, Calvo E, Belleau P, Martel C, Pelletier G, Morissette J, Labrie F, Durocher F.

Mol Reprod Dev. 2009 Mar;76(3):278-88. doi: 10.1002/mrd.20949.


Prostate-specific genes and their regulation by dihydrotestosterone.

Ma C, Yoshioka M, Boivin A, Belleau P, Gan L, Takase Y, Labrie F, St-Amand J.

Prostate. 2008 Feb 15;68(3):241-54. Erratum in: Prostate. 2008 Sep 1;68(12):1372. Ci, Ma [corrected to Ma, Ci]; Mayumi, Yoshioka [corrected to Yoshioka, Mayumi]; André, Boivin [corrected to Boivin, André]; Pascal, Belleau [corrected to Belleau, Pascal]; Lin, Gan [corrected to Gan, Lin]; Yasukazu, Takase [corrected to Takase, Yasukazu].


Gene interactions in depression: pathways out of darkness.

Harvey M, Belleau P, Barden N.

Trends Genet. 2007 Nov;23(11):547-56. Epub 2007 Oct 25.


Genetic variants and haplotype analyses of the ZBRK1/ZNF350 gene in high-risk non BRCA1/2 French Canadian breast and ovarian cancer families.

Desjardins S, Belleau P, Labrie Y, Ouellette G, Bessette P, Chiquette J, Laframboise R, Lépine J, Lespérance B, Pichette R, Plante M; INHERIT BRCAs, Durocher F.

Int J Cancer. 2008 Jan 1;122(1):108-16.


Temporal analysis of E2 transcriptional induction of PTP and MKP and downregulation of IGF-I pathway key components in the mouse uterus.

Ivanga M, Labrie Y, Calvo E, Belleau P, Martel C, Luu-The V, Morissette J, Labrie F, Durocher F.

Physiol Genomics. 2007 Mar 14;29(1):13-23.


Protein diversity is generated within the motin family of proteins by alternative pre-mRNA splicing.

Moreau J, Lord M, Boucher M, Belleau P, Fernandes MJ.

Gene. 2005 May 9;350(2):137-48. Epub 2005 Mar 29.


Analysis of microsatellite markers and single nucleotide polymorphisms in candidate genes for susceptibility to bipolar affective disorder in the chromosome 12Q24.31 region.

Shink E, Harvey M, Tremblay M, Gagné B, Belleau P, Raymond C, Labbé M, Dubé MP, Lafrenière RG, Barden N.

Am J Med Genet B Neuropsychiatr Genet. 2005 May 5;135B(1):50-8.


Reproducibility, bioinformatic analysis and power of the SAGE method to evaluate changes in transcriptome.

Dinel S, Bolduc C, Belleau P, Boivin A, Yoshioka M, Calvo E, Piedboeuf B, Snyder EE, Labrie F, St-Amand J.

Nucleic Acids Res. 2005 Feb 16;33(3):e26.


Tetrahydrogestrinone induces a genomic signature typical of a potent anabolic steroid.

Labrie F, Luu-The V, Calvo E, Martel C, Cloutier J, Gauthier S, Belleau P, Morissette J, Lévesque MH, Labrie C.

J Endocrinol. 2005 Feb;184(2):427-33.


Effects of dihydrotestosterone on adipose tissue measured by serial analysis of gene expression.

Bolduc C, Larose M, Yoshioka M, Ye P, Belleau P, Labrie C, Morissette J, Raymond V, Labrie F, St-Amand J.

J Mol Endocrinol. 2004 Oct;33(2):429-44.


Transcriptome of mouse uterus by serial analysis of gene expression (SAGE): comparison with skeletal muscle.

Larose M, St-Amand J, Yoshioka M, Belleau P, Morissette J, Labrie C, Raymond V, Labrie F.

Mol Reprod Dev. 2004 Jun;68(2):142-8.


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