Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 81

1.

Ferlin Overview: From Membrane to Cancer Biology.

Peulen O, Rademaker G, Anania S, Turtoi A, Bellahcène A, Castronovo V.

Cells. 2019 Aug 22;8(9). pii: E954. doi: 10.3390/cells8090954. Review.

2.

Myoferlin Contributes to the Metastatic Phenotype of Pancreatic Cancer Cells by Enhancing Their Migratory Capacity through the Control of Oxidative Phosphorylation.

Rademaker G, Costanza B, Anania S, Agirman F, Maloujahmoum N, Di Valentin E, Goval JJ, Bellahcène A, Castronovo V, Peulen O.

Cancers (Basel). 2019 Jun 19;11(6). pii: E853. doi: 10.3390/cancers11060853.

3.

Human colon cancer cells highly express myoferlin to maintain a fit mitochondrial network and escape p53-driven apoptosis.

Rademaker G, Costanza B, Bellier J, Herfs M, Peiffer R, Agirman F, Maloujahmoum N, Habraken Y, Delvenne P, Bellahcène A, Castronovo V, Peulen O.

Oncogenesis. 2019 Mar 8;8(3):21. doi: 10.1038/s41389-019-0130-6.

4.

Transforming growth factor beta-induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration.

Costanza B, Rademaker G, Tiamiou A, De Tullio P, Leenders J, Blomme A, Bellier J, Bianchi E, Turtoi A, Delvenne P, Bellahcène A, Peulen O, Castronovo V.

Int J Cancer. 2019 Sep 15;145(6):1570-1584. doi: 10.1002/ijc.32247. Epub 2019 Mar 28.

PMID:
30834519
5.

Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer.

Nokin MJ, Bellier J, Durieux F, Peulen O, Rademaker G, Gabriel M, Monseur C, Charloteaux B, Verbeke L, van Laere S, Roncarati P, Herfs M, Lambert C, Scheijen J, Schalkwijk C, Colige A, Caers J, Delvenne P, Turtoi A, Castronovo V, Bellahcène A.

Breast Cancer Res. 2019 Jan 23;21(1):11. doi: 10.1186/s13058-018-1095-7.

6.

Methylglyoxal, a potent inducer of AGEs, connects between diabetes and cancer.

Bellier J, Nokin MJ, Lardé E, Karoyan P, Peulen O, Castronovo V, Bellahcène A.

Diabetes Res Clin Pract. 2019 Feb;148:200-211. doi: 10.1016/j.diabres.2019.01.002. Epub 2019 Jan 18. Review.

PMID:
30664892
7.

Myoferlin controls mitochondrial structure and activity in pancreatic ductal adenocarcinoma, and affects tumor aggressiveness.

Rademaker G, Hennequière V, Brohée L, Nokin MJ, Lovinfosse P, Durieux F, Gofflot S, Bellier J, Costanza B, Herfs M, Peiffer R, Bettendorff L, Deroanne C, Thiry M, Delvenne P, Hustinx R, Bellahcène A, Castronovo V, Peulen O.

Oncogene. 2018 Aug;37(32):4398-4412. doi: 10.1038/s41388-018-0287-z. Epub 2018 May 3.

8.

Innovative methodology for the identification of soluble biomarkers in fresh tissues.

Costanza B, Turtoi A, Bellahcène A, Hirano T, Peulen O, Blomme A, Hennequière V, Mutijima E, Boniver J, Meuwis MA, Josse C, Koopmansch B, Segers K, Yokobori T, Fahmy K, Thiry M, Coimbra C, Garbacki N, Colige A, Baiwir D, Bours V, Louis E, Detry O, Delvenne P, Nishiyama M, Castronovo V.

Oncotarget. 2018 Jan 31;9(12):10665-10680. doi: 10.18632/oncotarget.24366. eCollection 2018 Feb 13.

9.

Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.

Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A.

Oncogene. 2018 Mar;37(9):1237-1250. doi: 10.1038/s41388-017-0018-x. Epub 2017 Dec 15.

PMID:
29242606
10.

Hormetic potential of methylglyoxal, a side-product of glycolysis, in switching tumours from growth to death.

Nokin MJ, Durieux F, Bellier J, Peulen O, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, Castronovo V, Bellahcène A.

Sci Rep. 2017 Sep 15;7(1):11722. doi: 10.1038/s41598-017-12119-7.

11.

Methylglyoxal-derived stress: An emerging biological factor involved in the onset and progression of cancer.

Bellahcène A, Nokin MJ, Castronovo V, Schalkwijk C.

Semin Cancer Biol. 2018 Apr;49:64-74. doi: 10.1016/j.semcancer.2017.05.010. Epub 2017 Jun 7. Review.

PMID:
28600198
12.

Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.

Chiavarina B, Nokin MJ, Bellier J, Durieux F, Bletard N, Sherer F, Lovinfosse P, Peulen O, Verset L, Dehon R, Demetter P, Turtoi A, Uchida K, Goldman S, Hustinx R, Delvenne P, Castronovo V, Bellahcène A.

Int J Mol Sci. 2017 Jan 21;18(1). pii: E213. doi: 10.3390/ijms18010213.

13.

[Asporin: the protective wall against triple-negative breast cancer].

Blomme A, Cusumano P, Peulen O, Bellahcène A, Castronovo V, Turtoi A.

Med Sci (Paris). 2016 Nov;32(11):1019-1022. doi: 10.1051/medsci/20163211020. Epub 2016 Dec 23. French. No abstract available.

14.

Myoferlin is a novel exosomal protein and functional regulator of cancer-derived exosomes.

Blomme A, Fahmy K, Peulen O, Costanza B, Fontaine M, Struman I, Baiwir D, de Pauw E, Thiry M, Bellahcène A, Castronovo V, Turtoi A.

Oncotarget. 2016 Dec 13;7(50):83669-83683. doi: 10.18632/oncotarget.13276.

15.

Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis.

Nokin MJ, Durieux F, Peixoto P, Chiavarina B, Peulen O, Blomme A, Turtoi A, Costanza B, Smargiasso N, Baiwir D, Scheijen JL, Schalkwijk CG, Leenders J, De Tullio P, Bianchi E, Thiry M, Uchida K, Spiegel DA, Cochrane JR, Hutton CA, De Pauw E, Delvenne P, Belpomme D, Castronovo V, Bellahcène A.

Elife. 2016 Oct 19;5. pii: e19375. doi: 10.7554/eLife.19375.

16.

Estrogen related receptor alpha in castration-resistant prostate cancer cells promotes tumor progression in bone.

Fradet A, Bouchet M, Delliaux C, Gervais M, Kan C, Benetollo C, Pantano F, Vargas G, Bouazza L, Croset M, Bala Y, Leroy X, Rosol TJ, Rieusset J, Bellahcène A, Castronovo V, Aubin JE, Clézardin P, Duterque-Coquillaud M, Bonnelye E.

Oncotarget. 2016 Nov 22;7(47):77071-77086. doi: 10.18632/oncotarget.12787.

17.

Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer.

Blomme A, Costanza B, de Tullio P, Thiry M, Van Simaeys G, Boutry S, Doumont G, Di Valentin E, Hirano T, Yokobori T, Gofflot S, Peulen O, Bellahcène A, Sherer F, Le Goff C, Cavalier E, Mouithys-Mickalad A, Jouret F, Cusumano PG, Lifrange E, Muller RN, Goldman S, Delvenne P, De Pauw E, Nishiyama M, Castronovo V, Turtoi A.

Oncogene. 2017 Apr;36(15):2116-2130. doi: 10.1038/onc.2016.369. Epub 2016 Oct 24.

PMID:
27775075
18.

Granulocytic myeloid-derived suppressor cells promote angiogenesis in the context of multiple myeloma.

Binsfeld M, Muller J, Lamour V, De Veirman K, De Raeve H, Bellahcène A, Van Valckenborgh E, Baron F, Beguin Y, Caers J, Heusschen R.

Oncotarget. 2016 Jun 21;7(25):37931-37943. doi: 10.18632/oncotarget.9270.

19.

New role of osteopontin in DNA repair and impact on human glioblastoma radiosensitivity.

Henry A, Nokin MJ, Leroi N, Lallemand F, Lambert J, Goffart N, Roncarati P, Bianchi E, Peixoto P, Blomme A, Turtoi A, Peulen O, Habraken Y, Scholtes F, Martinive P, Delvenne P, Rogister B, Castronovo V, Bellahcène A.

Oncotarget. 2016 Sep 27;7(39):63708-63721. doi: 10.18632/oncotarget.11483.

20.

HDAC7 inhibition resets STAT3 tumorigenic activity in human glioblastoma independently of EGFR and PTEN: new opportunities for selected targeted therapies.

Peixoto P, Blomme A, Costanza B, Ronca R, Rezzola S, Palacios AP, Schoysman L, Boutry S, Goffart N, Peulen O, Maris P, Di Valentin E, Hennequière V, Bianchi E, Henry A, Meunier P, Rogister B, Muller RN, Delvenne P, Bellahcène A, Castronovo V, Turtoi A.

Oncogene. 2016 Aug 25;35(34):4481-94. doi: 10.1038/onc.2015.506. Epub 2016 Feb 8.

PMID:
26853466
21.

Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer.

Maris P, Blomme A, Palacios AP, Costanza B, Bellahcène A, Bianchi E, Gofflot S, Drion P, Trombino GE, Di Valentin E, Cusumano PG, Maweja S, Jerusalem G, Delvenne P, Lifrange E, Castronovo V, Turtoi A.

PLoS Med. 2015 Sep 1;12(9):e1001871. doi: 10.1371/journal.pmed.1001871. eCollection 2015 Sep.

22.

Myoferlin plays a key role in VEGFA secretion and impacts tumor-associated angiogenesis in human pancreas cancer.

Fahmy K, Gonzalez A, Arafa M, Peixoto P, Bellahcène A, Turtoi A, Delvenne P, Thiry M, Castronovo V, Peulen O.

Int J Cancer. 2016 Feb 1;138(3):652-63. doi: 10.1002/ijc.29820. Epub 2015 Sep 8.

23.

Histone deacetylases and cancer-associated angiogenesis: current understanding of the biology and clinical perspectives.

Turtoi A, Peixoto P, Castronovo V, Bellahcène A.

Crit Rev Oncog. 2015;20(1-2):119-37. Review.

PMID:
25746107
24.

Targeting osteopontin suppresses glioblastoma stem-like cell character and tumorigenicity in vivo.

Lamour V, Henry A, Kroonen J, Nokin MJ, von Marschall Z, Fisher LW, Chau TL, Chariot A, Sanson M, Delattre JY, Turtoi A, Peulen O, Rogister B, Castronovo V, Bellahcène A.

Int J Cancer. 2015 Sep 1;137(5):1047-57. doi: 10.1002/ijc.29454. Epub 2015 May 21.

25.

Triple negative tumors accumulate significantly less methylglyoxal specific adducts than other human breast cancer subtypes.

Chiavarina B, Nokin MJ, Durieux F, Bianchi E, Turtoi A, Peulen O, Peixoto P, Irigaray P, Uchida K, Belpomme D, Delvenne P, Castronovo V, Bellahcène A.

Oncotarget. 2014 Jul 30;5(14):5472-82.

26.
27.

Identification and quantification of the main active anticancer alkaloids from the root of Glaucium flavum.

Bournine L, Bensalem S, Wauters JN, Iguer-Ouada M, Maiza-Benabdesselam F, Bedjou F, Castronovo V, Bellahcène A, Tits M, Frédérich M.

Int J Mol Sci. 2013 Dec 2;14(12):23533-44. doi: 10.3390/ijms141223533.

28.

[SIBLING proteins: molecular tools for tumor progression and angiogenesis].

Lamour V, Nokin MJ, Henry A, Castronovo V, Bellahcène A.

Med Sci (Paris). 2013 Nov;29(11):1018-25. doi: 10.1051/medsci/20132911019. Epub 2013 Nov 20. Review. French.

29.

A new murine model of osteoblastic/osteolytic lesions from human androgen-resistant prostate cancer.

Fradet A, Sorel H, Depalle B, Serre CM, Farlay D, Turtoi A, Bellahcene A, Follet H, Castronovo V, Clézardin P, Bonnelye E.

PLoS One. 2013 Sep 19;8(9):e75092. doi: 10.1371/journal.pone.0075092. eCollection 2013.

30.

Consequences of chondrocyte hypertrophy on osteoarthritic cartilage: potential effect on angiogenesis.

Pesesse L, Sanchez C, Delcour JP, Bellahcène A, Baudouin C, Msika P, Henrotin Y.

Osteoarthritis Cartilage. 2013 Dec;21(12):1913-23. doi: 10.1016/j.joca.2013.08.018. Epub 2013 Aug 22.

31.

Myoferlin is a key regulator of EGFR activity in breast cancer.

Turtoi A, Blomme A, Bellahcène A, Gilles C, Hennequière V, Peixoto P, Bianchi E, Noel A, De Pauw E, Lifrange E, Delvenne P, Castronovo V.

Cancer Res. 2013 Sep 1;73(17):5438-48. doi: 10.1158/0008-5472.CAN-13-1142. Epub 2013 Jul 17.

32.

Revealing the anti-tumoral effect of Algerian Glaucium flavum roots against human cancer cells.

Bournine L, Bensalem S, Peixoto P, Gonzalez A, Maiza-Benabdesselam F, Bedjou F, Wauters JN, Tits M, Frédérich M, Castronovo V, Bellahcène A.

Phytomedicine. 2013 Oct 15;20(13):1211-8. doi: 10.1016/j.phymed.2013.06.007. Epub 2013 Jul 13.

PMID:
23860409
33.

Overexpression of CD9 in human breast cancer cells promotes the development of bone metastases.

Kischel P, Bellahcene A, Deux B, Lamour V, Dobson R, DE Pauw E, Clezardin P, Castronovo V.

Anticancer Res. 2012 Dec;32(12):5211-20.

PMID:
23225418
34.

Galectin-1 in melanoma biology and related neo-angiogenesis processes.

Mathieu V, de Lassalle EM, Toelen J, Mohr T, Bellahcène A, Van Goietsenoven G, Verschuere T, Bouzin C, Debyser Z, De Vleeschouwer S, Van Gool S, Poirier F, Castronovo V, Kiss R, Feron O.

J Invest Dermatol. 2012 Sep;132(9):2245-54. doi: 10.1038/jid.2012.142. Epub 2012 May 24.

35.

The angiogenesis suppressor gene AKAP12 is under the epigenetic control of HDAC7 in endothelial cells.

Turtoi A, Mottet D, Matheus N, Dumont B, Peixoto P, Hennequière V, Deroanne C, Colige A, De Pauw E, Bellahcène A, Castronovo V.

Angiogenesis. 2012 Dec;15(4):543-54. doi: 10.1007/s10456-012-9279-8. Epub 2012 May 15.

36.

Both osteopontin-c and osteopontin-b splicing isoforms exert pro-tumorigenic roles in prostate cancer cells.

Tilli TM, Mello KD, Ferreira LB, Matos AR, Accioly MT, Faria PA, Bellahcène A, Castronovo V, Gimba ER.

Prostate. 2012 Nov;72(15):1688-99. doi: 10.1002/pros.22523. Epub 2012 Apr 11.

37.

Differential proteomic analysis of a human breast tumor and its matched bone metastasis identifies cell membrane and extracellular proteins associated with bone metastasis.

Dumont B, Castronovo V, Peulen O, Blétard N, Clézardin P, Delvenne P, De Pauw EA, Turtoi A, Bellahcène A.

J Proteome Res. 2012 Apr 6;11(4):2247-60. doi: 10.1021/pr201022n. Epub 2012 Mar 9.

38.

Role of the focal adhesion protein kindlin-1 in breast cancer growth and lung metastasis.

Sin S, Bonin F, Petit V, Meseure D, Lallemand F, Bièche I, Bellahcène A, Castronovo V, de Wever O, Gespach C, Lidereau R, Driouch K.

J Natl Cancer Inst. 2011 Sep 7;103(17):1323-37. doi: 10.1093/jnci/djr290. Epub 2011 Aug 10.

PMID:
21832234
39.

Dual function of ERRα in breast cancer and bone metastasis formation: implication of VEGF and osteoprotegerin.

Fradet A, Sorel H, Bouazza L, Goehrig D, Dépalle B, Bellahcène A, Castronovo V, Follet H, Descotes F, Aubin JE, Clézardin P, Bonnelye E.

Cancer Res. 2011 Sep 1;71(17):5728-38. doi: 10.1158/0008-5472.CAN-11-1431. Epub 2011 Jul 6.

40.

Dentin matrix protein 1 induces membrane expression of VE-cadherin on endothelial cells and inhibits VEGF-induced angiogenesis by blocking VEGFR-2 phosphorylation.

Pirotte S, Lamour V, Lambert V, Alvarez Gonzalez ML, Ormenese S, Noël A, Mottet D, Castronovo V, Bellahcène A.

Blood. 2011 Feb 24;117(8):2515-26. doi: 10.1182/blood-2010-08-298810. Epub 2010 Dec 29.

PMID:
21190990
41.

Nitrogen-containing bisphosphonates can inhibit angiogenesis in vivo without the involvement of farnesyl pyrophosphate synthase.

Stresing V, Fournier PG, Bellahcène A, Benzaïd I, Mönkkönen H, Colombel M, Ebetino FH, Castronovo V, Clézardin P.

Bone. 2011 Feb;48(2):259-66. doi: 10.1016/j.bone.2010.09.035. Epub 2010 Oct 20.

PMID:
20920623
42.

Selective osteopontin knockdown exerts anti-tumoral activity in a human glioblastoma model.

Lamour V, Le Mercier M, Lefranc F, Hagedorn M, Javerzat S, Bikfalvi A, Kiss R, Castronovo V, Bellahcène A.

Int J Cancer. 2010 Apr 15;126(8):1797-1805. doi: 10.1002/ijc.24751.

43.

HDAC4 represses p21(WAF1/Cip1) expression in human cancer cells through a Sp1-dependent, p53-independent mechanism.

Mottet D, Pirotte S, Lamour V, Hagedorn M, Javerzat S, Bikfalvi A, Bellahcène A, Verdin E, Castronovo V.

Oncogene. 2009 Jan 15;28(2):243-56. doi: 10.1038/onc.2008.371. Epub 2008 Oct 13.

PMID:
18850004
44.

Cell membrane proteomic analysis identifies proteins differentially expressed in osteotropic human breast cancer cells.

Kischel P, Guillonneau F, Dumont B, Bellahcène A, Stresing V, Clézardin P, De Pauw EA, Castronovo V.

Neoplasia. 2008 Sep;10(9):1014-20.

45.

A six-gene signature predicting breast cancer lung metastasis.

Landemaine T, Jackson A, Bellahcène A, Rucci N, Sin S, Abad BM, Sierra A, Boudinet A, Guinebretière JM, Ricevuto E, Noguès C, Briffod M, Bièche I, Cherel P, Garcia T, Castronovo V, Teti A, Lidereau R, Driouch K.

Cancer Res. 2008 Aug 1;68(15):6092-9. doi: 10.1158/0008-5472.CAN-08-0436.

46.

Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer.

Bellahcène A, Castronovo V, Ogbureke KU, Fisher LW, Fedarko NS.

Nat Rev Cancer. 2008 Mar;8(3):212-26. doi: 10.1038/nrc2345. Review.

47.

Phenotypic characterization of osteoblasts from the sclerotic zones of osteoarthritic subchondral bone.

Sanchez C, Deberg MA, Bellahcène A, Castronovo V, Msika P, Delcour JP, Crielaard JM, Henrotin YE.

Arthritis Rheum. 2008 Feb;58(2):442-55. doi: 10.1002/art.23159. Erratum in: Arthritis Rheum. 2008 Mar;58(3):887.

48.

Experimental anti-angiogenesis causes upregulation of genes associated with poor survival in glioblastoma.

Saidi A, Javerzat S, Bellahcène A, De Vos J, Bello L, Castronovo V, Deprez M, Loiseau H, Bikfalvi A, Hagedorn M.

Int J Cancer. 2008 May 15;122(10):2187-98.

49.

CREB-1 and AP-1 transcription factors JunD and Fra-2 regulate bone sialoprotein gene expression in human breast cancer cells.

Detry C, Lamour V, Castronovo V, Bellahcène A.

Bone. 2008 Feb;42(2):422-31. Epub 2007 Nov 1.

PMID:
18088579
50.

Runx2- and histone deacetylase 3-mediated repression is relieved in differentiating human osteoblast cells to allow high bone sialoprotein expression.

Lamour V, Detry C, Sanchez C, Henrotin Y, Castronovo V, Bellahcène A.

J Biol Chem. 2007 Dec 14;282(50):36240-9. Epub 2007 Oct 22.

Supplemental Content

Loading ...
Support Center