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A conserved Mcm4 motif is required for Mcm2-7 double-hexamer formation and origin DNA unwinding.

Champasa K, Blank C, Friedman LJ, Gelles J, Bell SP.

Elife. 2019 Aug 6;8. pii: e45538. doi: 10.7554/eLife.45538.


Frailty Is Related to Subjective Cognitive Decline in Older Women without Dementia.

Gifford KA, Bell SP, Liu D, Neal JE, Turchan M, Shah AS, Jefferson AL.

J Am Geriatr Soc. 2019 Sep;67(9):1803-1811. doi: 10.1111/jgs.15972. Epub 2019 May 16.


Initiation-specific alleles of the Cdc45 helicase-activating protein.

Rios-Morales RY, Chan SH, Bell SP.

PLoS One. 2019 Mar 26;14(3):e0214426. doi: 10.1371/journal.pone.0214426. eCollection 2019.


A patient-centered deprescribing intervention for hospitalized older patients with polypharmacy: rationale and design of the Shed-MEDS randomized controlled trial.

Vasilevskis EE, Shah AS, Hollingsworth EK, Shotwell MS, Mixon AS, Bell SP, Kripalani S, Schnelle JF, Simmons SF; Shed-MEDS Team.

BMC Health Serv Res. 2019 Mar 14;19(1):165. doi: 10.1186/s12913-019-3995-3.


Changes in vulnerability among older patients with cardiovascular disease in the first 90 days after hospital discharge: A secondary analysis of a cohort study.

Wang J, Dietrich MS, Bell SP, Maxwell CA, Simmons SF, Kripalani S; Vanderbilt Inpatient Cohort Study (VICS).

BMJ Open. 2019 Jan 29;9(1):e024766. doi: 10.1136/bmjopen-2018-024766.


The 12-Word Philadelphia Verbal Learning Test Performances in Older Adults: Brain MRI and Cerebrospinal Fluid Correlates and Regression-Based Normative Data.

Gifford KA, Liu D, Neal JE, Babicz MA, Thompson JL, Walljasper LE, Wiggins ME, Turchan M, Pechman KR, Osborn KE, Acosta LMY, Bell SP, Hohman TJ, Libon DJ, Blennow K, Zetterberg H, Jefferson AL.

Dement Geriatr Cogn Dis Extra. 2018 Dec 6;8(3):476-491. doi: 10.1159/000494209. eCollection 2018 Sep-Dec.


Timing of Left Ventricular Remodeling in Nonischemic Dilated Cardiomyopathy.

Bradham WS, Bell SP, Huang S, Harrell FE Jr, Adkisson DW, Lawson MA, Sawyer DB, Ooi H, Kronenberg MW.

Am J Med Sci. 2018 Sep;356(3):262-267. doi: 10.1016/j.amjms.2018.06.003. Epub 2018 Jun 8.


Transcriptional repression of CDC6 and SLD2 during meiosis is associated with production of short heterogeneous RNA isoforms.

Phizicky DV, Bell SP.

Chromosoma. 2018 Dec;127(4):515-527. doi: 10.1007/s00412-018-0681-x. Epub 2018 Oct 1.


Shed-MEDS: pilot of a patient-centered deprescribing framework reduces medications in hospitalized older adults being transferred to inpatient postacute care.

Petersen AW, Shah AS, Simmons SF, Shotwell MS, Jacobsen JML, Myers AP, Mixon AS, Bell SP, Kripalani S, Schnelle JF, Vasilevskis EE.

Ther Adv Drug Saf. 2018 Jun 15;9(9):523-533. doi: 10.1177/2042098618781524. eCollection 2018 Sep.


Neurofilament relates to white matter microstructure in older adults.

Moore EE, Hohman TJ, Badami FS, Pechman KR, Osborn KE, Acosta LMY, Bell SP, Babicz MA, Gifford KA, Anderson AW, Goldstein LE, Blennow K, Zetterberg H, Jefferson AL.

Neurobiol Aging. 2018 Oct;70:233-241. doi: 10.1016/j.neurobiolaging.2018.06.023. Epub 2018 Jun 28.


Higher Aortic Stiffness Is Related to Lower Cerebral Blood Flow and Preserved Cerebrovascular Reactivity in Older Adults.

Jefferson AL, Cambronero FE, Liu D, Moore EE, Neal JE, Terry JG, Nair S, Pechman KR, Rane S, Davis LT, Gifford KA, Hohman TJ, Bell SP, Wang TJ, Beckman JA, Carr JJ.

Circulation. 2018 Oct 30;138(18):1951-1962. doi: 10.1161/CIRCULATIONAHA.118.032410.


Increased Left Ventricular Mass Index Is Associated With Compromised White Matter Microstructure Among Older Adults.

Moore EE, Liu D, Pechman KR, Terry JG, Nair S, Cambronero FE, Bell SP, Gifford KA, Anderson AW, Hohman TJ, Carr JJ, Jefferson AL.

J Am Heart Assoc. 2018 Jun 26;7(13). pii: e009041. doi: 10.1161/JAHA.118.009041.


Validity and Normative Data for the Biber Figure Learning Test: A Visual Supraspan Memory Measure.

Gifford KA, Liu D, Neal JE, Acosta LMY, Bell SP, Wiggins ME, Wisniewski KM, Godfrey M, Logan LA, Hohman TJ, Pechman KR, Libon DJ, Blennow K, Zetterberg H, Jefferson AL.

Assessment. 2018 May 1:1073191118773870. doi: 10.1177/1073191118773870. [Epub ahead of print]


Multimorbidity in Older Adults With Cardiovascular Disease.

Forman DE, Maurer MS, Boyd C, Brindis R, Salive ME, Horne FM, Bell SP, Fulmer T, Reuben DB, Zieman S, Rich MW.

J Am Coll Cardiol. 2018 May 15;71(19):2149-2161. doi: 10.1016/j.jacc.2018.03.022. Review.


Cerebrospinal fluid β-amyloid42 and neurofilament light relate to white matter hyperintensities.

Osborn KE, Liu D, Samuels LR, Moore EE, Cambronero FE, Acosta LMY, Bell SP, Babicz MA, Gordon EA, Pechman KR, Davis LT, Gifford KA, Hohman TJ, Blennow K, Zetterberg H, Jefferson AL.

Neurobiol Aging. 2018 Aug;68:18-25. doi: 10.1016/j.neurobiolaging.2018.03.028. Epub 2018 Apr 3.


APOE genotype modifies the association between central arterial stiffening and cognition in older adults.

Cambronero FE, Liu D, Neal JE, Moore EE, Gifford KA, Terry JG, Nair S, Pechman KR, Osborn KE, Hohman TJ, Bell SP, Sweatt JD, Wang TJ, Beckman JA, Carr JJ, Jefferson AL.

Neurobiol Aging. 2018 Jul;67:120-127. doi: 10.1016/j.neurobiolaging.2018.02.009. Epub 2018 Feb 20.


Subclinical Compromise in Cardiac Strain Relates to Lower Cognitive Performances in Older Adults.

Kresge HA, Khan OA, Wagener MA, Liu D, Terry JG, Nair S, Cambronero FE, Gifford KA, Osborn KE, Hohman TJ, Pechman KR, Bell SP, Wang TJ, Carr JJ, Jefferson AL.

J Am Heart Assoc. 2018 Feb 13;7(4). pii: e007562. doi: 10.1161/JAHA.117.007562.


Multiple kinases inhibit origin licensing and helicase activation to ensure reductive cell division during meiosis.

Phizicky DV, Berchowitz LE, Bell SP.

Elife. 2018 Feb 1;7. pii: e33309. doi: 10.7554/eLife.33309.


Acute Kidney Injury and Subsequent Frailty Status in Survivors of Critical Illness: A Secondary Analysis.

Abdel-Kader K, Girard TD, Brummel NE, Saunders CT, Blume JD, Clark AJ, Vincz AJ, Ely EW, Jackson JC, Bell SP, Archer KR, Ikizler TA, Pandharipande PP, Siew ED.

Crit Care Med. 2018 May;46(5):e380-e388. doi: 10.1097/CCM.0000000000003003.


Late-Life Body Mass Index, Rapid Weight Loss, Apolipoprotein E ε4 and the Risk of Cognitive Decline and Incident Dementia.

Bell SP, Liu D, Samuels LR, Shah AS, Gifford KA, Hohman TJ, Jefferson AL.

J Nutr Health Aging. 2017;21(10):1259-1267. doi: 10.1007/s12603-017-0906-3.


Lower cardiac index levels relate to lower cerebral blood flow in older adults.

Jefferson AL, Liu D, Gupta DK, Pechman KR, Watchmaker JM, Gordon EA, Rane S, Bell SP, Mendes LA, Davis LT, Gifford KA, Hohman TJ, Wang TJ, Donahue MJ.

Neurology. 2017 Dec 5;89(23):2327-2334. doi: 10.1212/WNL.0000000000004707. Epub 2017 Nov 8.


Replication origin-flanking roadblocks reveal origin-licensing dynamics and altered sequence dependence.

Warner MD, Azmi IF, Kang S, Zhao Y, Bell SP.

J Biol Chem. 2017 Dec 29;292(52):21417-21430. doi: 10.1074/jbc.M117.815639. Epub 2017 Oct 26.


Relaxation and the Role of Calcium in Isolated Contracting Myocardium From Patients With Hypertensive Heart Disease and Heart Failure With Preserved Ejection Fraction.

Runte KE, Bell SP, Selby DE, Häußler TN, Ashikaga T, LeWinter MM, Palmer BM, Meyer M.

Circ Heart Fail. 2017 Aug;10(8). pii: e004311. doi: 10.1161/CIRCHEARTFAILURE.117.004311.


Nucleosomes influence multiple steps during replication initiation.

Azmi IF, Watanabe S, Maloney MF, Kang S, Belsky JA, MacAlpine DM, Peterson CL, Bell SP.

Elife. 2017 Mar 21;6. pii: e22512. doi: 10.7554/eLife.22512.


Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase.

Lõoke M, Maloney MF, Bell SP.

Genes Dev. 2017 Feb 1;31(3):291-305. doi: 10.1101/gad.291336.116.


Mechanism and timing of Mcm2-7 ring closure during DNA replication origin licensing.

Ticau S, Friedman LJ, Champasa K, Corrêa IR Jr, Gelles J, Bell SP.

Nat Struct Mol Biol. 2017 Mar;24(3):309-315. doi: 10.1038/nsmb.3375. Epub 2017 Feb 13.


Rethinking origin licensing.

Bell SP.

Elife. 2017 Jan 19;6. pii: e24052. doi: 10.7554/eLife.24052.


Potentially Avoidable Readmissions of Patients Discharged to Post-Acute Care: Perspectives of Hospital and Skilled Nursing Facility Staff.

Vasilevskis EE, Ouslander JG, Mixon AS, Bell SP, Jacobsen JM, Saraf AA, Markley D, Sponsler KC, Shutes J, Long EA, Kripalani S, Simmons SF, Schnelle JF.

J Am Geriatr Soc. 2017 Feb;65(2):269-276. doi: 10.1111/jgs.14557. Epub 2016 Dec 16.


Myocardial T1 Measurement Predicts Beneficial LV Remodeling After Long-Term Heart Failure Therapy.

Bradham WS, Bell SP, Adkisson DW, Smith HM, Harrell FE Jr, Lawson MA, Ooi H, Sawyer DB, Kronenberg MW.

J Card Fail. 2017 Mar;23(3):262-265. doi: 10.1016/j.cardfail.2016.11.008. Epub 2016 Dec 8.


Frailty and Subsequent Disability and Mortality among Patients with Critical Illness.

Brummel NE, Bell SP, Girard TD, Pandharipande PP, Jackson JC, Morandi A, Thompson JL, Chandrasekhar R, Bernard GR, Dittus RS, Gill TM, Ely EW.

Am J Respir Crit Care Med. 2017 Jul 1;196(1):64-72. doi: 10.1164/rccm.201605-0939OC.


Chromosome Duplication in Saccharomyces cerevisiae.

Bell SP, Labib K.

Genetics. 2016 Jul;203(3):1027-67. doi: 10.1534/genetics.115.186452. Review.


Medications associated with geriatric syndromes and their prevalence in older hospitalized adults discharged to skilled nursing facilities.

Saraf AA, Petersen AW, Simmons SF, Schnelle JF, Bell SP, Kripalani S, Myers AP, Mixon AS, Long EA, Jacobsen JM, Vasilevskis EE.

J Hosp Med. 2016 Oct;11(10):694-700. doi: 10.1002/jhm.2614. Epub 2016 Jun 3.


Epidemiology of Multimorbidity in Older Adults with Cardiovascular Disease.

Bell SP, Saraf AA.

Clin Geriatr Med. 2016 May;32(2):215-26. doi: 10.1016/j.cger.2016.01.013. Review.


Geriatric Syndromes in Hospitalized Older Adults Discharged to Skilled Nursing Facilities.

Bell SP, Vasilevskis EE, Saraf AA, Jacobsen JM, Kripalani S, Mixon AS, Schnelle JF, Simmons SF.

J Am Geriatr Soc. 2016 Apr;64(4):715-22. doi: 10.1111/jgs.14035. Epub 2016 Apr 5.


The Vanderbilt Memory & Aging Project: Study Design and Baseline Cohort Overview.

Jefferson AL, Gifford KA, Acosta LM, Bell SP, Donahue MJ, Davis LT, Gottlieb J, Gupta DK, Hohman TJ, Lane EM, Libon DJ, Mendes LA, Niswender K, Pechman KR, Rane S, Ruberg FL, Su YR, Zetterberg H, Liu D.

J Alzheimers Dis. 2016 Mar 8;52(2):539-59. doi: 10.3233/JAD-150914.


Preparedness for hospital discharge and prediction of readmission.

Mixon AS, Goggins K, Bell SP, Vasilevskis EE, Nwosu S, Schildcrout JS, Kripalani S.

J Hosp Med. 2016 Sep;11(9):603-9. doi: 10.1002/jhm.2572. Epub 2016 Feb 29. Review.


Care of older adults.

Bell SP, Patel N, Patel N, Sonani R, Badheka A, Forman DE.

J Geriatr Cardiol. 2016 Jan;13(1):1-7. doi: 10.11909/j.issn.1671-5411.2016.01.019. No abstract available.


Effect of Pharmacist Counseling Intervention on Health Care Utilization Following Hospital Discharge: A Randomized Control Trial.

Bell SP, Schnipper JL, Goggins K, Bian A, Shintani A, Roumie CL, Dalal AK, Jacobson TA, Rask KJ, Vaccarino V, Gandhi TK, Labonville SA, Johnson D, Neal EB, Kripalani S; Pharmacist Intervention for Low Literacy in Cardiovascular Disease (PILL-CVD) Study Group.

J Gen Intern Med. 2016 May;31(5):470-7. doi: 10.1007/s11606-016-3596-3.


Effect of Health Literacy on Research Follow-Up.

Leak C, Goggins K, Schildcrout JS, Theobald C, Donato KM, Bell SP, Schnelle J, Kripalani S; Vanderbilt Inpatient Cohort Study.

J Health Commun. 2015;20 Suppl 2:83-91. doi: 10.1080/10810730.2015.1058442.


What to Expect From the Evolving Field of Geriatric Cardiology.

Bell SP, Orr NM, Dodson JA, Rich MW, Wenger NK, Blum K, Harold JG, Tinetti ME, Maurer MS, Forman DE.

J Am Coll Cardiol. 2015 Sep 15;66(11):1286-1299. doi: 10.1016/j.jacc.2015.07.048. Review.


Development of a multivariable model to predict vulnerability in older American patients hospitalised with cardiovascular disease.

Bell SP, Schnelle J, Nwosu SK, Schildcrout J, Goggins K, Cawthon C, Mixon AS, Vasilevskis EE, Kripalani S; Vanderbilt Inpatient Cohort Study.

BMJ Open. 2015 Aug 27;5(8):e008122. doi: 10.1136/bmjopen-2015-008122.


Associations between Verbal Learning Slope and Neuroimaging Markers across the Cognitive Aging Spectrum.

Gifford KA, Phillips JS, Samuels LR, Lane EM, Bell SP, Liu D, Hohman TJ, Romano RR 3rd, Fritzsche LR, Lu Z, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

J Int Neuropsychol Soc. 2015 Jul;21(6):455-67. doi: 10.1017/S1355617715000430.


The dynamics of eukaryotic replication initiation: origin specificity, licensing, and firing at the single-molecule level.

Duzdevich D, Warner MD, Ticau S, Ivica NA, Bell SP, Greene EC.

Mol Cell. 2015 May 7;58(3):483-94. doi: 10.1016/j.molcel.2015.03.017. Epub 2015 Apr 23.


Single-molecule studies of origin licensing reveal mechanisms ensuring bidirectional helicase loading.

Ticau S, Friedman LJ, Ivica NA, Gelles J, Bell SP.

Cell. 2015 Apr 23;161(3):513-525. doi: 10.1016/j.cell.2015.03.012. Epub 2015 Apr 16.


The role of vascular endothelial growth factor in neurodegeneration and cognitive decline: exploring interactions with biomarkers of Alzheimer disease.

Hohman TJ, Bell SP, Jefferson AL; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Neurol. 2015 May;72(5):520-9. doi: 10.1001/jamaneurol.2014.4761.


High reproducibility of adenosine stress cardiac MR myocardial perfusion imaging in patients with non-ischaemic dilated cardiomyopathy.

Lawson MA, Bell SP, Adkisson DW, Wang L, Ooi H, Sawyer DB, Kronenberg MW.

BMJ Open. 2014 Dec 16;4(12):e005984. doi: 10.1136/bmjopen-2014-005984.


DNA Replication. Terminating the replisome.

Bell SP.

Science. 2014 Oct 24;346(6208):418-9. doi: 10.1126/science.1261245. No abstract available.


Predictors of health care system and physician distrust in hospitalized cardiac patients.

Gupta C, Bell SP, Schildcrout JS, Fletcher S, Goggins KM, Kripalani S; Vanderbilt Inpatient Cohort Study (VICS).

J Health Commun. 2014;19 Suppl 2:44-60. doi: 10.1080/10810730.2014.934936.


Risk stratification in very old adults: how to best gauge risk as the basis of management choices for patients aged over 80.

Bell SP, Saraf A.

Prog Cardiovasc Dis. 2014 Sep-Oct;57(2):197-203. doi: 10.1016/j.pcad.2014.08.001. Epub 2014 Aug 4. Review.


Antifailure therapy including spironolactone improves left ventricular energy supply-demand relations in nonischemic dilated cardiomyopathy.

Bell SP, Adkisson DW, Lawson MA, Wang L, Ooi H, Sawyer DB, Kronenberg MW.

J Am Heart Assoc. 2014 Aug 27;3(4). pii: e000883. doi: 10.1161/JAHA.114.000883.

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