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Dengue genetic divergence generates within-serotype antigenic variation, but serotypes dominate evolutionary dynamics.

Bell SM, Katzelnick L, Bedford T.

Elife. 2019 Aug 6;8. pii: e42496. doi: 10.7554/eLife.42496.


Altered frontal and insular functional connectivity as pivotal mechanisms for apathy in Alzheimer's disease.

Jones SA, De Marco M, Manca R, Bell SM, Blackburn DJ, Wilkinson ID, Soininen H, Venneri A.

Cortex. 2019 Apr 20;119:100-110. doi: 10.1016/j.cortex.2019.04.008. [Epub ahead of print]


Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.

Guo M, Du Y, Gokey JJ, Ray S, Bell SM, Adam M, Sudha P, Perl AK, Deshmukh H, Potter SS, Whitsett JA, Xu Y.

Nat Commun. 2019 Jan 3;10(1):37. doi: 10.1038/s41467-018-07770-1.


Management of Refractory Ventricular Fibrillation (Prehospital and Emergency Department).

Bell SM, Lam DH, Kearney K, Hira RS.

Cardiol Clin. 2018 Aug;36(3):395-408. doi: 10.1016/j.ccl.2018.03.007. Review.


A MAPK/c-Jun-mediated switch regulates the initial adaptive and cell death responses to mitochondrial damage in a neuronal cell model.

Ryan TA, Roper KM, Bond J, Bell SM, Sweeney ST, Morrison EE.

Int J Biochem Cell Biol. 2018 Nov;104:73-86. doi: 10.1016/j.biocel.2018.09.008. Epub 2018 Sep 17.


Estimating Vaccine-Driven Selection in Seasonal Influenza.

Wen FT, Bell SM, Bedford T, Cobey S.

Viruses. 2018 Sep 18;10(9). pii: E509. doi: 10.3390/v10090509.


Ursodeoxycholic Acid Improves Mitochondrial Function and Redistributes Drp1 in Fibroblasts from Patients with Either Sporadic or Familial Alzheimer's Disease.

Bell SM, Barnes K, Clemmens H, Al-Rafiah AR, Al-Ofi EA, Leech V, Bandmann O, Shaw PJ, Blackburn DJ, Ferraiuolo L, Mortiboys H.

J Mol Biol. 2018 Oct 19;430(21):3942-3953. doi: 10.1016/j.jmb.2018.08.019. Epub 2018 Aug 29.


Characterization of Primary Cilia in Normal Fallopian Tube Epithelium and Serous Tubal Intraepithelial Carcinoma.

Abdelhamed ZA, Ryan TA, Fuller M, Coulson-Gilmer C, Abdelmottaleb DI, Wang TL, Kaun JC, Wang P, Hutson R, Wilkinson N, Bell SM, Johnson CA.

Int J Gynecol Cancer. 2018 Oct;28(8):1535-1544. doi: 10.1097/IGC.0000000000001321.


A Pilot Study Investigating a Novel Non-Linear Measure of Eyes Open versus Eyes Closed EEG Synchronization in People with Alzheimer’s Disease and Healthy Controls

Blackburn DJ, Zhao Y, De Marco M, Bell SM, He F, Wei HL, Lawrence S, Unwin ZC, Blyth M, Angel J, Baster K, Farrow TFD, Wilkinson ID, Billings SA, Venneri A, Sarrigiannis PG.

Brain Sci. 2018 Jul 17;8(7). pii: E134. doi: 10.3390/brainsci8070134.


Expression analysis of the MCPH1/BRIT1 and BRCA1 tumor suppressor genes and telomerase splice variants in epithelial ovarian cancer.

Alsiary R, Brownhill SC, Brüning-Richardson A, Hutson R, Griffin N, Morrison EE, Bond J, Burchill SA, Bell SM.

Gene. 2018 Sep 25;672:34-44. doi: 10.1016/j.gene.2018.05.113. Epub 2018 May 31.


Nextstrain: real-time tracking of pathogen evolution.

Hadfield J, Megill C, Bell SM, Huddleston J, Potter B, Callender C, Sagulenko P, Bedford T, Neher RA.

Bioinformatics. 2018 Dec 1;34(23):4121-4123. doi: 10.1093/bioinformatics/bty407.


Concomitant Use of Antiplatelets and Anticoagulants in Patients with Coronary Heart Disease and Atrial Fibrillation: What Do Recent Clinical Trials Teach Us?

Lam DH, Bell SM, Hira RS.

Curr Atheroscler Rep. 2018 Jan 19;20(1):4. doi: 10.1007/s11883-018-0703-4. Review.


In vitro to in vivo extrapolation for high throughput prioritization and decision making.

Bell SM, Chang X, Wambaugh JF, Allen DG, Bartels M, Brouwer KLR, Casey WM, Choksi N, Ferguson SS, Fraczkiewicz G, Jarabek AM, Ke A, Lumen A, Lynn SG, Paini A, Price PS, Ring C, Simon TW, Sipes NS, Sprankle CS, Strickland J, Troutman J, Wetmore BA, Kleinstreuer NC.

Toxicol In Vitro. 2018 Mar;47:213-227. doi: 10.1016/j.tiv.2017.11.016. Epub 2017 Dec 5. Review.


Treatment of the unknown patient: insights from acute stroke.

Bell SM, Sokhi D, Hughes T, Randall MS.

Pract Neurol. 2017 Dec;17(6):453-455. doi: 10.1136/practneurol-2017-001626. Epub 2017 Jul 25.


Modern-day SIV viral diversity generated by extensive recombination and cross-species transmission.

Bell SM, Bedford T.

PLoS Pathog. 2017 Jul 3;13(7):e1006466. doi: 10.1371/journal.ppat.1006466. eCollection 2017 Jul.


An Integrated Chemical Environment to Support 21st-Century Toxicology.

Bell SM, Phillips J, Sedykh A, Tandon A, Sprankle C, Morefield SQ, Shapiro A, Allen D, Shah R, Maull EA, Casey WM, Kleinstreuer NC.

Environ Health Perspect. 2017 May 25;125(5):054501. doi: 10.1289/EHP1759.


Loss of CSMD1 expression disrupts mammary duct formation while enhancing proliferation, migration and invasion.

Kamal M, Holliday DL, Morrison EE, Speirs V, Toomes C, Bell SM.

Oncol Rep. 2017 Jul;38(1):283-292. doi: 10.3892/or.2017.5656. Epub 2017 May 22.


Elevated donor hemoglobin A1c does not impair early survival in cardiac transplant recipients.

Joseph JT, Mulvihill MS, Yerokun BA, Bell SM, Milano CA, Hartwig MG.

Clin Transplant. 2017 Jul;31(7). doi: 10.1111/ctr.12995. Epub 2017 Jun 10.


Formulation and PEGylation optimization of the therapeutic PEGylated phenylalanine ammonia lyase for the treatment of phenylketonuria.

Bell SM, Wendt DJ, Zhang Y, Taylor TW, Long S, Tsuruda L, Zhao B, Laipis P, Fitzpatrick PA.

PLoS One. 2017 Mar 10;12(3):e0173269. doi: 10.1371/journal.pone.0173269. eCollection 2017.


A career in stroke medicine.

Bell SM, Cooper J, Doubal F, Hart S, Harkness K.

BMJ. 2017 Feb 6;356:i6372. doi: 10.1136/sbmj.i6372. No abstract available.


How the UK describes functional memory symptoms.

Bailey C, Bell SM, Blackburn DM.

Psychogeriatrics. 2017 Sep;17(5):336-337. doi: 10.1111/psyg.12232. Epub 2017 Feb 1. No abstract available.


Cellular Uptake and Delivery of Myeloperoxidase to Lysosomes Promote Lipofuscin Degradation and Lysosomal Stress in Retinal Cells.

Yogalingam G, Lee AR, Mackenzie DS, Maures TJ, Rafalko A, Prill H, Berguig GY, Hague C, Christianson T, Bell SM, LeBowitz JH.

J Biol Chem. 2017 Mar 10;292(10):4255-4265. doi: 10.1074/jbc.M116.739441. Epub 2017 Jan 23.


Hydrodynamic Assessment of Aortic Valves Prepared from Porcine Small Intestinal Submucosa.

Ramaswamy S, Lordeus M, Mankame OV, Valdes-Cruz L, Bibevski S, Bell SM, Baez I, Scholl F.

Cardiovasc Eng Technol. 2017 Mar;8(1):30-40. doi: 10.1007/s13239-016-0290-x. Epub 2016 Dec 19.


Airway Epithelial KIF3A Regulates Th2 Responses to Aeroallergens.

Giridhar PV, Bell SM, Sridharan A, Rajavelu P, Kitzmiller JA, Na CL, Kofron M, Brandt EB, Ericksen M, Naren AP, Moon C, Khurana Hershey GK, Whitsett JA.

J Immunol. 2016 Dec 1;197(11):4228-4239. Epub 2016 Oct 28.


Autologous hematopoietic cell transplantation in multiple sclerosis.

Bell SM, Sharrack B, Snowden JA.

Expert Opin Biol Ther. 2017 Jan;17(1):77-86. Epub 2016 Oct 14. Review.


Integrating Publicly Available Data to Generate Computationally Predicted Adverse Outcome Pathways for Fatty Liver.

Bell SM, Angrish MM, Wood CE, Edwards SW.

Toxicol Sci. 2016 Apr;150(2):510-20. doi: 10.1093/toxsci/kfw017. Epub 2016 Feb 19.


Clearance of bile and trypsin in rat lungs following aspiration of human gastric fluid.

Leung JH, Chang JC, Foltz E, Bell SM, Pi C, Azad S, Everett ML, Holzknecht ZE, Sanders NL, Parker W, Davis RD, Keshavjee S, Lin SS.

Exp Lung Res. 2016;42(1):37-43. doi: 10.3109/01902148.2016.1139213.


The role of soluble and insoluble gastric fluid components in the pathogenesis of obliterative bronchiolitis in rat lung allografts.

Leung JH, Chang JC, Bell SM, Holzknecht ZE, Thomas SM, Everett ML, Parker W, Davis RD, Lin SS.

Transpl Int. 2016 Feb;29(2):253-61. doi: 10.1111/tri.12715. Epub 2015 Dec 17.


Patients who are not driving 6 weeks after transient ischaemic attack have higher levels of anxiety.

Bell SM, Maniam R, Patel A, Harkness K, Blackburn D.

Psychogeriatrics. 2017 Mar;17(2):146. doi: 10.1111/psyg.12194. Epub 2016 Jan 27. No abstract available.


Accelerating Adverse Outcome Pathway Development Using Publicly Available Data Sources.

Oki NO, Nelms MD, Bell SM, Mortensen HM, Edwards SW.

Curr Environ Health Rep. 2016 Mar;3(1):53-63. doi: 10.1007/s40572-016-0079-y. Review.


Epidemiology of Intracerebral Haemorrhage.

Poon MT, Bell SM, Al-Shahi Salman R.

Front Neurol Neurosci. 2015;37:1-12. doi: 10.1159/000437109. Epub 2015 Nov 12. Review.


An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

Wheway G, Schmidts M, Mans DA, Szymanska K, Nguyen TT, Racher H, Phelps IG, Toedt G, Kennedy J, Wunderlich KA, Sorusch N, Abdelhamed ZA, Natarajan S, Herridge W, van Reeuwijk J, Horn N, Boldt K, Parry DA, Letteboer SJF, Roosing S, Adams M, Bell SM, Bond J, Higgins J, Morrison EE, Tomlinson DC, Slaats GG, van Dam TJP, Huang L, Kessler K, Giessl A, Logan CV, Boyle EA, Shendure J, Anazi S, Aldahmesh M, Al Hazzaa S, Hegele RA, Ober C, Frosk P, Mhanni AA, Chodirker BN, Chudley AE, Lamont R, Bernier FP, Beaulieu CL, Gordon P, Pon RT, Donahue C, Barkovich AJ, Wolf L, Toomes C, Thiel CT, Boycott KM, McKibbin M, Inglehearn CF; UK10K Consortium; University of Washington Center for Mendelian Genomics, Stewart F, Omran H, Huynen MA, Sergouniotis PI, Alkuraya FS, Parboosingh JS, Innes AM, Willoughby CE, Giles RH, Webster AR, Ueffing M, Blacque O, Gleeson JG, Wolfrum U, Beales PL, Gibson T, Doherty D, Mitchison HM, Roepman R, Johnson CA.

Nat Cell Biol. 2015 Aug;17(8):1074-1087. doi: 10.1038/ncb3201. Epub 2015 Jul 13.


Identification and Prioritization of Relationships between Environmental Stressors and Adverse Human Health Impacts.

Bell SM, Edwards SW.

Environ Health Perspect. 2015 Nov;123(11):1193-9. doi: 10.1289/ehp.1409138. Epub 2015 Apr 10.


Neutral endopeptidase-resistant C-type natriuretic peptide variant represents a new therapeutic approach for treatment of fibroblast growth factor receptor 3-related dwarfism.

Wendt DJ, Dvorak-Ewell M, Bullens S, Lorget F, Bell SM, Peng J, Castillo S, Aoyagi-Scharber M, O'Neill CA, Krejci P, Wilcox WR, Rimoin DL, Bunting S.

J Pharmacol Exp Ther. 2015 Apr;353(1):132-49. doi: 10.1124/jpet.114.218560. Epub 2015 Feb 3.


Systematic Omics Analysis Review (SOAR) tool to support risk assessment.

McConnell ER, Bell SM, Cote I, Wang RL, Perkins EJ, Garcia-Reyero N, Gong P, Burgoon LD.

PLoS One. 2014 Dec 22;9(12):e110379. doi: 10.1371/journal.pone.0110379. eCollection 2014.


Cerebral amyloid angiopathy: amyloid spells and cortical superficial siderosis.

Coates R, Bell SM, Coley S, Blackburn DJ.

Pract Neurol. 2015 Apr;15(2):124-6. doi: 10.1136/practneurol-2014-000952. Epub 2014 Oct 30. No abstract available.


Using the electronic health record to connect primary care patients to evidence-based telephonic tobacco quitline services: a closed-loop demonstration project.

Adsit RT, Fox BM, Tsiolis T, Ogland C, Simerson M, Vind LM, Bell SM, Skora AD, Baker TB, Fiore MC.

Transl Behav Med. 2014 Sep;4(3):324-32. doi: 10.1007/s13142-014-0259-y.


Erythrocyte-mediated delivery of phenylalanine ammonia lyase for the treatment of phenylketonuria in BTBR-Pah(enu2) mice.

Rossi L, Pierigè F, Carducci C, Gabucci C, Pascucci T, Canonico B, Bell SM, Fitzpatrick PA, Leuzzi V, Magnani M.

J Control Release. 2014 Nov 28;194:37-44. doi: 10.1016/j.jconrel.2014.08.012. Epub 2014 Aug 23.


Defining success in graduate school.

Bell SM, Blumstein J, Brose K, Carroll A, Chang J, Charles J, Haswell ES, Michelitsch M, Owens JC, Patil CK, Smith R, Tupy J, Walsh E, Ware T.

Mol Biol Cell. 2014 Jul 1;25(13):1942-4. doi: 10.1091/mbc.E14-03-0793.


Deregulation of microcephalin and ASPM expression are correlated with epithelial ovarian cancer progression.

Alsiary R, Brüning-Richardson A, Bond J, Morrison EE, Wilkinson N, Bell SM.

PLoS One. 2014 May 15;9(5):e97059. doi: 10.1371/journal.pone.0097059. eCollection 2014.


Development of an internal amplification control system for a real-time PCR assay for detection of Neisseria meningitidis in CSF and EDTA blood.

McIver CJ, Bell SM, Er N.

Pathology. 2014 Jun;46(4):344-7. doi: 10.1097/PAT.0000000000000098.


High-content, high-throughput screening for the identification of cytotoxic compounds based on cell morphology and cell proliferation markers.

Martin HL, Adams M, Higgins J, Bond J, Morrison EE, Bell SM, Warriner S, Nelson A, Tomlinson DC.

PLoS One. 2014 Feb 5;9(2):e88338. doi: 10.1371/journal.pone.0088338. eCollection 2014.


Regulation of estrogen receptor β1 expression in breast cancer by epigenetic modification of the 5' regulatory region.

Al-Nakhle H, Smith L, Bell SM, Burns PA, Cummings M, Hanby AM, Lane S, Parker MD, Hughes TA, Speirs V.

Int J Oncol. 2013 Dec;43(6):2039-45. doi: 10.3892/ijo.2013.2112. Epub 2013 Sep 25.


A high-throughput assay to identify modifiers of premature chromosome condensation.

Adams M, Cookson VJ, Higgins J, Martin HL, Tomlinson DC, Bond J, Morrison EE, Bell SM.

J Biomol Screen. 2014 Jan;19(1):176-83. doi: 10.1177/1087057113495443. Epub 2013 Aug 27.


Limited diversity in the gene pool allows prediction of third-generation cephalosporin and aminoglycoside resistance in Escherichia coli and Klebsiella pneumoniae.

Ginn AN, Zong Z, Wiklendt AM, Thomas LC, Merlino J, Gottlieb T, van Hal S, Harkness J, Macleod C, Bell SM, Leroi MJ, Partridge SR, Iredell JR.

Int J Antimicrob Agents. 2013 Jul;42(1):19-26. doi: 10.1016/j.ijantimicag.2013.03.003. Epub 2013 May 21.


Delineating a conserved genetic cassette promoting outgrowth of body appendages.

Lin C, Yin Y, Bell SM, Veith GM, Chen H, Huh SH, Ornitz DM, Ma L.

PLoS Genet. 2013;9(1):e1003231. doi: 10.1371/journal.pgen.1003231. Epub 2013 Jan 24.


Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium.

Bell SM, Zhang L, Xu Y, Besnard V, Wert SE, Shroyer N, Whitsett JA.

Dev Biol. 2013 Mar 15;375(2):128-39. doi: 10.1016/j.ydbio.2012.12.010. Epub 2012 Dec 22.


Evaluation of the therapeutic potential of a CNP analog in a Fgfr3 mouse model recapitulating achondroplasia.

Lorget F, Kaci N, Peng J, Benoist-Lasselin C, Mugniery E, Oppeneer T, Wendt DJ, Bell SM, Bullens S, Bunting S, Tsuruda LS, O'Neill CA, Di Rocco F, Munnich A, Legeai-Mallet L.

Am J Hum Genet. 2012 Dec 7;91(6):1108-14. doi: 10.1016/j.ajhg.2012.10.014. Epub 2012 Nov 29.


Development and validation of an assessment of adult educators' reading instructional knowledge.

Bell SM, McCallum RS, Ziegler M, Davis CA, Coleman M.

Ann Dyslexia. 2013 Oct;63(3-4):187-200. doi: 10.1007/s11881-012-0079-z. Epub 2012 Nov 14.


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