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Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches.

Orth M, Metzger P, Gerum S, Mayerle J, Schneider G, Belka C, Schnurr M, Lauber K.

Radiat Oncol. 2019 Aug 8;14(1):141. doi: 10.1186/s13014-019-1345-6. Review.


Factors associated with the decline of psychological support in hospitalized patients with cancer.

Pichler T, Dinkel A, Marten-Mittag B, Hermelink K, Telzerow E, Ackermann U, Belka C, Combs SE, Gratzke C, Gschwend J, Harbeck N, Heinemann V, Herkommer K, Kiechle M, Mahner S, Pigorsch S, Rauch J, Stief C, Beckmann J, Heußner P, Herschbach P.

Psychooncology. 2019 Aug 1. doi: 10.1002/pon.5191. [Epub ahead of print]


Report of first recurrent glioma patients examined with PET-MRI prior to re-irradiation.

Fleischmann DF, Unterrainer M, Corradini S, Rottler M, Förster S, la Fougère C, Siepmann T, Schwaiger M, Bartenstein P, Belka C, Albert NL, Niyazi M.

PLoS One. 2019 Jul 24;14(7):e0216111. doi: 10.1371/journal.pone.0216111. eCollection 2019.


Impact of surface-guided positioning on the use of portal imaging and initial set-up duration in breast cancer patients.

Pazos M, Walter F, Reitz D, Schönecker S, Konnerth D, Schäfer A, Rottler M, Alongi F, Freislederer P, Niyazi M, Belka C, Corradini S.

Strahlenther Onkol. 2019 Jul 22. doi: 10.1007/s00066-019-01494-x. [Epub ahead of print]


Baseline T1 hyperintense and diffusion-restricted lesions are not linked to prolonged survival in bevacizumab-treated glioblastoma patients of the GLARIUS trial.

Kebir S, Schaub C, Junold N, Hattingen E, Schäfer N, Steinbach JP, Weyerbrock A, Hau P, Goldbrunner R, Galldiks N, Weller J, Mack F, Tzaridis T, Bähr O, Seidel C, Schlegel U, Schmidt-Graf F, Rohde V, Borchers C, Tabatabai G, Hänel M, Sabel M, Gerlach R, Krex D, Belka C, Vatter H, Proescholdt M, Glas M, Herrlinger U.

J Neurooncol. 2019 Jul 19. doi: 10.1007/s11060-019-03246-4. [Epub ahead of print]


Evaluation of proton and photon dose distributions recalculated on 2D and 3D Unet-generated pseudoCTs from T1-weighted MR head scans.

Neppl S, Landry G, Kurz C, Hansen DC, Hoyle B, Stöcklein S, Seidensticker M, Weller J, Belka C, Parodi K, Kamp F.

Acta Oncol. 2019 Jul 4:1-6. doi: 10.1080/0284186X.2019.1630754. [Epub ahead of print]


Towards a novel small animal proton irradiation platform: the SIRMIO project.

Parodi K, Assmann W, Belka C, Bortfeldt J, Clevert DA, Dedes G, Kalunga R, Kundel S, Kurichiyanil N, Lämmer P, Lascaud J, Lauber K, Lovatti G, Meyer S, Nitta M, Pinto M, Safari MJ, Schnürle K, Schreiber J, Thirolf PG, Wieser HP, Würl M.

Acta Oncol. 2019 Jul 4:1-6. doi: 10.1080/0284186X.2019.1630752. [Epub ahead of print]


Bevacizumab reduces toxicity of reirradiation in recurrent high-grade glioma.

Fleischmann DF, Jenn J, Corradini S, Ruf V, Herms J, Forbrig R, Unterrainer M, Thon N, Kreth FW, Belka C, Niyazi M.

Radiother Oncol. 2019 Jun 25;138:99-105. doi: 10.1016/j.radonc.2019.06.009. [Epub ahead of print]


Safety evaluation of nivolumab added concurrently to radiotherapy in a standard first line chemo-radiotherapy regimen in stage III non-small cell lung cancer-The ETOP NICOLAS trial.

Peters S, Felip E, Dafni U, Belka C, Guckenberger M, Irigoyen A, Nadal E, Becker A, Vees H, Pless M, Martinez-Marti A, Tufman A, Lambrecht M, Andratschke N, Piguet AC, Kassapian M, Roschitzki-Voser H, Rabaglio-Poretti M, Stahel RA, Vansteenkiste J, De Ruysscher D.

Lung Cancer. 2019 Jul;133:83-87. doi: 10.1016/j.lungcan.2019.05.001. Epub 2019 May 3.


Single isocenter stereotactic radiosurgery for patients with multiple brain metastases: dosimetric comparison of VMAT and a dedicated DCAT planning tool.

Hofmaier J, Bodensohn R, Garny S, Hadi I, Fleischmann DF, Eder M, Dinc Y, Reiner M, Corradini S, Parodi K, Belka C, Niyazi M.

Radiat Oncol. 2019 Jun 11;14(1):103. doi: 10.1186/s13014-019-1315-z.


Interference of tumour mutational burden with outcome of patients with head and neck cancer treated with definitive chemoradiation: a multicentre retrospective study of the German Cancer Consortium Radiation Oncology Group.

Eder T, Hess AK, Konschak R, Stromberger C, Jöhrens K, Fleischer V, Hummel M, Balermpas P, von der Grün J, Linge A, Lohaus F, Krause M, Baumann M, Stuschke M, Zips D, Grosu AL, Abdollahi A, Debus J, Belka C, Pigorsch S, Combs SE, Budach V, Tinhofer I; DKTK-ROG.

Eur J Cancer. 2019 Jul;116:67-76. doi: 10.1016/j.ejca.2019.04.015. Epub 2019 Jun 4.


MR-guidance in clinical reality: current treatment challenges and future perspectives.

Corradini S, Alongi F, Andratschke N, Belka C, Boldrini L, Cellini F, Debus J, Guckenberger M, Hörner-Rieber J, Lagerwaard FJ, Mazzola R, Palacios MA, Philippens MEP, Raaijmakers CPJ, Terhaard CHJ, Valentini V, Niyazi M.

Radiat Oncol. 2019 Jun 3;14(1):92. doi: 10.1186/s13014-019-1308-y. Review.


Prospective evaluation of a tumor control probability model based on dynamic 18F-FMISO PET for head-and-neck cancer radiotherapy.

Thorwarth D, Welz S, Mönnich D, Pfannenberg C, Nikolaou K, Reimold M, la Fougère C, Reischl G, Mauz PS, Paulsen F, Alber ML, Belka C, Zips D.

J Nucl Med. 2019 May 10. pii: jnumed.119.227744. doi: 10.2967/jnumed.119.227744. [Epub ahead of print]


Erratum: "ScatterNet: A convolutional neural network for cone-beam CT intensity correction" [Med. Phys. 45, 4916-4926 (2018)].

Hansen DC, Landry G, Kamp F, Li M, Belka C, Parodi K, Kurz C.

Med Phys. 2019 May;46(5):2538. doi: 10.1002/mp.13469. Epub 2019 Mar 23. No abstract available.


Comparison of planned dose on different CT image sets to four-dimensional Monte Carlo dose recalculation using the patient's actual breathing trace for lung stereotactic body radiation therapy.

Freislederer P, von Münchow A, Kamp F, Heinz C, Gerum S, Corradini S, Söhn M, Reiner M, Roeder F, Floca R, Alber M, Belka C, Parodi K.

Med Phys. 2019 Jul;46(7):3268-3277. doi: 10.1002/mp.13579. Epub 2019 Jun 7.


Dosimetric accuracy and radiobiological implications of ion computed tomography for proton therapy treatment planning.

Meyer S, Kamp F, Tessonnier T, Mairani A, Belka C, Carlson DJ, Gianoli C, Parodi K.

Phys Med Biol. 2019 Jun 12;64(12):125008. doi: 10.1088/1361-6560/ab0fdf.


Mastectomy or Breast-Conserving Therapy for Early Breast Cancer in Real-Life Clinical Practice: Outcome Comparison of 7565 Cases.

Corradini S, Reitz D, Pazos M, Schönecker S, Braun M, Harbeck N, Matuschek C, Bölke E, Ganswindt U, Alongi F, Niyazi M, Belka C.

Cancers (Basel). 2019 Jan 31;11(2). pii: E160. doi: 10.3390/cancers11020160.


State of clinical research of radiotherapy/chemoradiotherapy and immune checkpoint inhibitor therapy combinations in solid tumours-a German radiation oncology survey.

Käsmann L, Eze C, Dantes M, Roengvoraphoj O, Niyazi M, Belka C, Manapov F.

Eur J Cancer. 2019 Feb;108:50-54. doi: 10.1016/j.ejca.2018.11.026. Epub 2019 Jan 12.


Impact of 68Ga-PSMA PET/CT on the Radiotherapeutic Approach to Prostate Cancer in Comparison to CT: A Retrospective Analysis.

Schmidt-Hegemann NS, Eze C, Li M, Rogowski P, Schaefer C, Stief C, Buchner A, Zamboglou C, Fendler WP, Ganswindt U, Cyran C, Bartenstein P, Belka C, Ilhan H.

J Nucl Med. 2019 Jul;60(7):963-970. doi: 10.2967/jnumed.118.220855. Epub 2018 Dec 14.


Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells.

Krombach J, Hennel R, Brix N, Orth M, Schoetz U, Ernst A, Schuster J, Zuchtriegel G, Reichel CA, Bierschenk S, Sperandio M, Vogl T, Unkel S, Belka C, Lauber K.

Oncoimmunology. 2018 Nov 2;8(1):e1523097. doi: 10.1080/2162402X.2018.1523097. eCollection 2019.


Comparing Unet training with three different datasets to correct CBCT images for prostate radiotherapy dose calculations.

Landry G, Hansen D, Kamp F, Li M, Hoyle B, Weller J, Parodi K, Belka C, Kurz C.

Phys Med Biol. 2019 Jan 24;64(3):035011. doi: 10.1088/1361-6560/aaf496.


Optical Surface Scanning for Patient Positioning in Radiation Therapy: A Prospective Analysis of 1902 Fractions.

Carl G, Reitz D, Schönecker S, Pazos M, Freislederer P, Reiner M, Alongi F, Niyazi M, Ganswindt U, Belka C, Corradini S.

Technol Cancer Res Treat. 2018 Jan 1;17:1533033818806002. doi: 10.1177/1533033818806002.


Feasibility of 4DCBCT-based proton dose calculation: An ex vivo porcine lung phantom study.

Niepel K, Kamp F, Kurz C, Hansen D, Rit S, Neppl S, Hofmaier J, Bondesson D, Thieke C, Dinkel J, Belka C, Parodi K, Landry G.

Z Med Phys. 2018 Nov 14. pii: S0939-3889(18)30066-7. doi: 10.1016/j.zemedi.2018.10.005. [Epub ahead of print]


Dose-guided patient positioning in proton radiotherapy using multicriteria-optimization.

Kurz C, Süss P, Arnsmeyer C, Haehnle J, Teichert K, Landry G, Hofmaier J, Exner F, Hille L, Kamp F, Thieke C, Ganswindt U, Valentini C, Hölscher T, Troost E, Krause M, Belka C, Küfer KH, Parodi K, Richter C.

Z Med Phys. 2018 Nov 5. pii: S0939-3889(18)30062-X. doi: 10.1016/j.zemedi.2018.10.003. [Epub ahead of print]


Progressive resistance training in cachectic head and neck cancer patients undergoing radiotherapy: a randomized controlled pilot feasibility trial.

Grote M, Maihöfer C, Weigl M, Davies-Knorr P, Belka C.

Radiat Oncol. 2018 Nov 6;13(1):215. doi: 10.1186/s13014-018-1157-0.


Toward a new treatment planning approach accounting for in vivo proton range verification.

Tian L, Landry G, Dedes G, Kamp F, Pinto M, Niepel K, Belka C, Parodi K.

Phys Med Biol. 2018 Oct 30;63(21):215025. doi: 10.1088/1361-6560/aae749.


Prophylactic cranial irradiation in small-cell lung cancer: update on patient selection, efficacy and outcomes.

Manapov F, Käsmann L, Roengvoraphoj O, Dantes M, Schmidt-Hegemann NS, Belka C, Eze C.

Lung Cancer (Auckl). 2018 Aug 16;9:49-55. doi: 10.2147/LCTT.S137577. eCollection 2018. Review.


Recent Developments in Radiation Oncology: An Overview of Individualised Treatment Strategies in Breast Cancer.

Pazos M, Schönecker S, Reitz D, Rogowski P, Niyazi M, Alongi F, Matuschek C, Braun M, Harbeck N, Belka C, Corradini S.

Breast Care (Basel). 2018 Aug;13(4):285-291. doi: 10.1159/000488189. Epub 2018 May 24. Review.


High Expression of EpCAM and Sox2 is a Positive Prognosticator of Clinical Outcome for Head and Neck Carcinoma.

Baumeister P, Hollmann A, Kitz J, Afthonidou A, Simon F, Shakhtour J, Mack B, Kranz G, Libl D, Leu M, Schirmer MA, Canis M, Belka C, Zitzelsberger H, Ganswindt U, Hess J, Jakob M, Unger K, Gires O.

Sci Rep. 2018 Oct 1;8(1):14582. doi: 10.1038/s41598-018-32178-8.


A prognostic mRNA expression signature of four 16q24.3 genes in radio(chemo)therapy-treated head and neck squamous cell carcinoma (HNSCC).

Wintergerst L, Selmansberger M, Maihoefer C, Schüttrumpf L, Walch A, Wilke C, Pitea A, Woischke C, Baumeister P, Kirchner T, Belka C, Ganswindt U, Zitzelsberger H, Unger K, Hess J.

Mol Oncol. 2018 Dec;12(12):2085-2101. doi: 10.1002/1878-0261.12388. Epub 2018 Oct 26.


Comparison of 18F-GE-180 and dynamic 18F-FET PET in high grade glioma: a double-tracer pilot study.

Unterrainer M, Fleischmann DF, Diekmann C, Vomacka L, Lindner S, Vettermann F, Brendel M, Wenter V, Ertl-Wagner B, Herms J, Wetzel C, Rupprecht R, Tonn JC, Belka C, Bartenstein P, Niyazi M, Albert NL.

Eur J Nucl Med Mol Imaging. 2019 Mar;46(3):580-590. doi: 10.1007/s00259-018-4166-1. Epub 2018 Sep 22.


ScatterNet: A convolutional neural network for cone-beam CT intensity correction.

Hansen DC, Landry G, Kamp F, Li M, Belka C, Parodi K, Kurz C.

Med Phys. 2018 Nov;45(11):4916-4926. doi: 10.1002/mp.13175. Epub 2018 Oct 8. Erratum in: Med Phys. 2019 May;46(5):2538.


Prophylactic Cranial Irradiation for Patients with Small Cell Lung Cancer in Germany: Pattern of Care Survey.

Eze C, Roengvoraphoj O, Dantes M, Abdo R, Käsmann L, Schmidt-Hegemann NS, Belka C, Manapov F.

Anticancer Res. 2018 Sep;38(9):5261-5265. doi: 10.21873/anticanres.12851.


A Five-MicroRNA Signature Predicts Survival and Disease Control of Patients with Head and Neck Cancer Negative for HPV Infection.

Hess J, Unger K, Maihoefer C, Schüttrumpf L, Wintergerst L, Heider T, Weber P, Marschner S, Braselmann H, Samaga D, Kuger S, Pflugradt U, Baumeister P, Walch A, Woischke C, Kirchner T, Werner M, Werner K, Baumann M, Budach V, Combs SE, Debus J, Grosu AL, Krause M, Linge A, Rödel C, Stuschke M, Zips D, Zitzelsberger H, Ganswindt U, Henke M, Belka C.

Clin Cancer Res. 2019 Mar 1;25(5):1505-1516. doi: 10.1158/1078-0432.CCR-18-0776. Epub 2018 Aug 31.


Dose variability in different lymph node levels during locoregional breast cancer irradiation: the impact of deep-inspiration breath hold.

Pazos M, Fiorentino A, Gaasch A, Schönecker S, Reitz D, Heinz C, Niyazi M, Duma MN, Alongi F, Belka C, Corradini S.

Strahlenther Onkol. 2019 Jan;195(1):13-20. doi: 10.1007/s00066-018-1350-y. Epub 2018 Aug 24.


Does deep inspiration breath-hold prolong life? Individual risk estimates of ischaemic heart disease after breast cancer radiotherapy.

Simonetto C, Eidemüller M, Gaasch A, Pazos M, Schönecker S, Reitz D, Kääb S, Braun M, Harbeck N, Niyazi M, Belka C, Corradini S.

Radiother Oncol. 2019 Feb;131:202-207. doi: 10.1016/j.radonc.2018.07.024. Epub 2018 Aug 7.


Pattern of care of adjuvant radiotherapy in male breast cancer patients in clinical practice: an observational study.

Rogowski P, Schönecker S, Pazos M, Reitz D, Braun M, Pölcher M, Hanusch C, Wuerstlein R, Harbeck N, Mahner S, Belka C, Corradini S.

Strahlenther Onkol. 2019 Apr;195(4):289-296. doi: 10.1007/s00066-018-1337-8. Epub 2018 Jul 25.


Real-time intra-fraction motion management in breast cancer radiotherapy: analysis of 2028 treatment sessions.

Reitz D, Carl G, Schönecker S, Pazos M, Freislederer P, Niyazi M, Ganswindt U, Alongi F, Reiner M, Belka C, Corradini S.

Radiat Oncol. 2018 Jul 16;13(1):128. doi: 10.1186/s13014-018-1072-4.


[Immuncheckpoint Inhibitors: Current Indications and Possible Future Concepts].

Schlaak M, Baues C, Trommer-Nestler M, Berking C, Belka C, Theurich S.

Dtsch Med Wochenschr. 2018 Jul;143(14):1014-1021. doi: 10.1055/s-0043-125001. Epub 2018 Jul 13. German.


Outcome after PSMA PET/CT based salvage radiotherapy in patients with biochemical recurrence after radical prostatectomy: a bi-institutional retrospective analysis.

Schmidt-Hegemann NS, Stief C, Kim TH, Eze C, Kirste S, Strouthos I, Li M, Schultze-Seemann W, Ilhan H, Fendler WP, Bartenstein P, Grosu AL, Ganswindt U, Belka C, Meyer PT, Zamboglou C.

J Nucl Med. 2018 Jul 12. pii: jnumed.118.212563. doi: 10.2967/jnumed.118.212563. [Epub ahead of print]


Postoperative (chemo) radiation in patients with squamous cell cancers of the head and neck - clinical results from the cohort of the clinical cooperation group "Personalized Radiotherapy in Head and Neck Cancer".

Maihoefer C, Schüttrumpf L, Macht C, Pflugradt U, Hess J, Schneider L, Woischke C, Walch A, Baumeister P, Kirchner T, Zitzelsberger H, Belka C, Ganswindt U.

Radiat Oncol. 2018 Jul 3;13(1):123. doi: 10.1186/s13014-018-1067-1.


Combined intracavitary and interstitial brachytherapy of cervical cancer using the novel hybrid applicator Venezia: Clinical feasibility and initial results.

Walter F, Maihöfer C, Schüttrumpf L, Well J, Burges A, Ertl-Wagner B, Mahner S, Belka C, Gallwas J, Corradini S.

Brachytherapy. 2018 Sep - Oct;17(5):775-781. doi: 10.1016/j.brachy.2018.05.009. Epub 2018 Jun 22.


Recurrence pattern analysis after [68Ga]-DOTATATE-PET/CT -planned radiotherapy of high-grade meningiomas.

Zollner B, Ganswindt U, Maihöfer C, Corradini S, Albert NL, Schichor C, Belka C, Niyazi M.

Radiat Oncol. 2018 Jun 14;13(1):110. doi: 10.1186/s13014-018-1056-4.


How much primary tumor metabolic volume reduction is required to improve outcome in stage III NSCLC after chemoradiotherapy? A single-centre experience.

Roengvoraphoj O, Eze C, Wijaya C, Dantes M, Taugner J, Tufman A, Huber RM, Bartenstein P, Belka C, Manapov F.

Eur J Nucl Med Mol Imaging. 2018 Nov;45(12):2103-2109. doi: 10.1007/s00259-018-4063-7. Epub 2018 Jun 6.


Stereotactic body radiation therapy (SBRT) in patients with hepatocellular carcinoma and oligometastatic liver disease.

Gerum S, Heinz C, Belka C, Walter F, Paprottka P, De Toni EN, Roeder F.

Radiat Oncol. 2018 May 29;13(1):100. doi: 10.1186/s13014-018-1048-4.


Tumor growth patterns of MGMT-non-methylated glioblastoma in the randomized GLARIUS trial.

Schaub C, Kebir S, Junold N, Hattingen E, Schäfer N, Steinbach JP, Weyerbrock A, Hau P, Goldbrunner R, Niessen M, Mack F, Stuplich M, Tzaridis T, Bähr O, Kortmann RD, Schlegel U, Schmidt-Graf F, Rohde V, Braun C, Hänel M, Sabel M, Gerlach R, Krex D, Belka C, Vatter H, Proescholdt M, Herrlinger U, Glas M.

J Cancer Res Clin Oncol. 2018 Aug;144(8):1581-1589. doi: 10.1007/s00432-018-2671-z. Epub 2018 May 28.


Clinical outcome of elderly patients (≥ 70 years) with esophageal cancer undergoing definitive or neoadjuvant radio(chemo)therapy: a retrospective single center analysis.

Walter F, Böckle D, Schmidt-Hegemann NS, Köpple R, Gerum S, Boeck S, Angele M, Belka C, Roeder F.

Radiat Oncol. 2018 May 16;13(1):93. doi: 10.1186/s13014-018-1044-8.


PSMA-PET based radiotherapy: a review of initial experiences, survey on current practice and future perspectives.

Zschaeck S, Lohaus F, Beck M, Habl G, Kroeze S, Zamboglou C, Koerber SA, Debus J, Hölscher T, Wust P, Ganswindt U, Baur ADJ, Zöphel K, Cihoric N, Guckenberger M, Combs SE, Grosu AL, Ghadjar P, Belka C.

Radiat Oncol. 2018 May 11;13(1):90. doi: 10.1186/s13014-018-1047-5. Review.


Detection of Cerebrospinal Fluid Dissemination of Recurrent Glioblastoma Using TSPO-PET With 18F-GE-180.

Unterrainer M, Fleischmann DF, Lindner S, Brendel M, Rupprecht R, Tonn JC, Belka C, Bartenstein P, Niyazi M, Albert NL.

Clin Nucl Med. 2018 Jul;43(7):518-519. doi: 10.1097/RLU.0000000000002113.


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