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Succinate dehydrogenase deficiency in a PDGFRA mutated GIST.

Belinsky MG, Cai KQ, Zhou Y, Luo B, Pei J, Rink L, von Mehren M.

BMC Cancer. 2017 Aug 2;17(1):512. doi: 10.1186/s12885-017-3499-7. Review.


Duodenal-Jejunal Flexure GI Stromal Tumor Frequently Heralds Somatic NF1 and Notch Pathway Mutations.

Burgoyne AM, De Siena M, Alkhuziem M, Tang CM, Medina B, Fanta PT, Belinsky MG, von Mehren M, Thorson JA, Madlensky L, Bowler T, D'Angelo F, Stupack DG, Harismendy O, DeMatteo RP, Sicklick JK.

JCO Precis Oncol. 2017;2017. doi: 10.1200/PO.17.00014. Epub 2017 Aug 15.


Combination of Imatinib Mesylate and AKT Inhibitor Provides Synergistic Effects in Preclinical Study of Gastrointestinal Stromal Tumor.

Zook P, Pathak HB, Belinsky MG, Gersz L, Devarajan K, Zhou Y, Godwin AK, von Mehren M, Rink L.

Clin Cancer Res. 2017 Jan 1;23(1):171-180. doi: 10.1158/1078-0432.CCR-16-0529. Epub 2016 Jul 1.


Somatic loss of function mutations in neurofibromin 1 and MYC associated factor X genes identified by exome-wide sequencing in a wild-type GIST case.

Belinsky MG, Rink L, Cai KQ, Capuzzi SJ, Hoang Y, Chien J, Godwin AK, von Mehren M.

BMC Cancer. 2015 Nov 10;15:887. doi: 10.1186/s12885-015-1872-y.


The application of social impact bonds to universal health-care initiatives in South-East Asia.

Belinsky M, Eddy M, Lohmann J, Georgea M.

WHO South East Asia J Public Health. 2014 Jul-Dec;3(3):219-225. doi: 10.4103/2224-3151.206744. Review.


Succinate dehydrogenase deficiency in pediatric and adult gastrointestinal stromal tumors.

Belinsky MG, Rink L, von Mehren M.

Front Oncol. 2013 May 17;3:117. doi: 10.3389/fonc.2013.00117. eCollection 2013.


Overexpression of insulin-like growth factor 1 receptor and frequent mutational inactivation of SDHA in wild-type SDHB-negative gastrointestinal stromal tumors.

Belinsky MG, Rink L, Flieder DB, Jahromi MS, Schiffman JD, Godwin AK, Mehren Mv.

Genes Chromosomes Cancer. 2013 Feb;52(2):214-24. doi: 10.1002/gcc.22023. Epub 2012 Oct 29.


Contribution of Abcc10 (Mrp7) to in vivo paclitaxel resistance as assessed in Abcc10(-/-) mice.

Hopper-Borge EA, Churchill T, Paulose C, Nicolas E, Jacobs JD, Ngo O, Kuang Y, Grinberg A, Westphal H, Chen ZS, Klein-Szanto AJ, Belinsky MG, Kruh GD.

Cancer Res. 2011 May 15;71(10):3649-57. doi: 10.1158/0008-5472.CAN-10-3623.


Gene expression signatures and response to imatinib mesylate in gastrointestinal stromal tumor.

Rink L, Skorobogatko Y, Kossenkov AV, Belinsky MG, Pajak T, Heinrich MC, Blanke CD, von Mehren M, Ochs MF, Eisenberg B, Godwin AK.

Mol Cancer Ther. 2009 Aug;8(8):2172-82. doi: 10.1158/1535-7163.MCT-09-0193. Epub 2009 Aug 11.


High density DNA array analysis reveals distinct genomic profiles in a subset of gastrointestinal stromal tumors.

Belinsky MG, Skorobogatko YV, Rink L, Pei J, Cai KQ, Vanderveer LA, Riddell D, Merkel E, Tarn C, Eisenberg BL, von Mehren M, Testa JR, Godwin AK.

Genes Chromosomes Cancer. 2009 Oct;48(10):886-96. doi: 10.1002/gcc.20689.


The insulin-like growth factor system as a potential therapeutic target in gastrointestinal stromal tumors.

Belinsky MG, Rink L, Cai KQ, Ochs MF, Eisenberg B, Huang M, von Mehren M, Godwin AK.

Cell Cycle. 2008 Oct;7(19):2949-55. Epub 2008 Oct 7. Review.


The organic solute transporter alpha-beta, Ostalpha-Ostbeta, is essential for intestinal bile acid transport and homeostasis.

Rao A, Haywood J, Craddock AL, Belinsky MG, Kruh GD, Dawson PA.

Proc Natl Acad Sci U S A. 2008 Mar 11;105(10):3891-6. doi: 10.1073/pnas.0712328105. Epub 2008 Feb 21.


Impact of basolateral multidrug resistance-associated protein (Mrp) 3 and Mrp4 on the hepatobiliary disposition of fexofenadine in perfused mouse livers.

Tian X, Swift B, Zamek-Gliszczynski MJ, Belinsky MG, Kruh GD, Brouwer KL.

Drug Metab Dispos. 2008 May;36(5):911-5. doi: 10.1124/dmd.107.019273. Epub 2008 Feb 14.


Targeted ablation of Abcc1 or Abcc3 in Abcc6(-/-) mice does not modify the ectopic mineralization process.

Li Q, Jiang Q, Larusso J, Klement JF, Sartorelli AC, Belinsky MG, Kruh GD, Uitto J.

Exp Dermatol. 2007 Oct;16(10):853-9.


Determination of methotrexate and its major metabolite 7-hydroxymethotrexate in mouse plasma and brain tissue by liquid chromatography-tandem mass spectrometry.

Guo P, Wang X, Liu L, Belinsky MG, Kruh GD, Gallo JM.

J Pharm Biomed Anal. 2007 Apr 11;43(5):1789-95. Epub 2007 Jan 12.


Physiological and pharmacological functions of Mrp2, Mrp3 and Mrp4 as determined from recent studies on gene-disrupted mice.

Kruh GD, Belinsky MG, Gallo JM, Lee K.

Cancer Metastasis Rev. 2007 Mar;26(1):5-14. Review.


Multidrug resistance protein 4 protects bone marrow, thymus, spleen, and intestine from nucleotide analogue-induced damage.

Belinsky MG, Guo P, Lee K, Zhou F, Kotova E, Grinberg A, Westphal H, Shchaveleva I, Klein-Szanto A, Gallo JM, Kruh GD.

Cancer Res. 2007 Jan 1;67(1):262-8.


ABCC10, ABCC11, and ABCC12.

Kruh GD, Guo Y, Hopper-Borge E, Belinsky MG, Chen ZS.

Pflugers Arch. 2007 Feb;453(5):675-84. Epub 2006 Jul 26. Review.


Analysis of the in vivo functions of Mrp3.

Belinsky MG, Dawson PA, Shchaveleva I, Bain LJ, Wang R, Ling V, Chen ZS, Grinberg A, Westphal H, Klein-Szanto A, Lerro A, Kruh GD.

Mol Pharmacol. 2005 Jul;68(1):160-8. Epub 2005 Apr 6.


Transport of bile acids, sulfated steroids, estradiol 17-beta-D-glucuronide, and leukotriene C4 by human multidrug resistance protein 8 (ABCC11).

Chen ZS, Guo Y, Belinsky MG, Kotova E, Kruh GD.

Mol Pharmacol. 2005 Feb;67(2):545-57. Epub 2004 Nov 10.


Analysis of the drug resistance profile of multidrug resistance protein 7 (ABCC10): resistance to docetaxel.

Hopper-Borge E, Chen ZS, Shchaveleva I, Belinsky MG, Kruh GD.

Cancer Res. 2004 Jul 15;64(14):4927-30.


Hyperfine splittings in spin-frustrated trinuclear Cu(3) clusters.

Belinsky MI.

Inorg Chem. 2004 Jan 26;43(2):739-46.


The MRP family of drug efflux pumps.

Kruh GD, Belinsky MG.

Oncogene. 2003 Oct 20;22(47):7537-52. Review.


Transport of methotrexate, methotrexate polyglutamates, and 17beta-estradiol 17-(beta-D-glucuronide) by ABCG2: effects of acquired mutations at R482 on methotrexate transport.

Chen ZS, Robey RW, Belinsky MG, Shchaveleva I, Ren XQ, Sugimoto Y, Ross DD, Bates SE, Kruh GD.

Cancer Res. 2003 Jul 15;63(14):4048-54.


MRP8, ATP-binding cassette C11 (ABCC11), is a cyclic nucleotide efflux pump and a resistance factor for fluoropyrimidines 2',3'-dideoxycytidine and 9'-(2'-phosphonylmethoxyethyl)adenine.

Guo Y, Kotova E, Chen ZS, Lee K, Hopper-Borge E, Belinsky MG, Kruh GD.

J Biol Chem. 2003 Aug 8;278(32):29509-14. Epub 2003 May 22.


Characterization of the transport properties of human multidrug resistance protein 7 (MRP7, ABCC10).

Chen ZS, Hopper-Borge E, Belinsky MG, Shchaveleva I, Kotova E, Kruh GD.

Mol Pharmacol. 2003 Feb;63(2):351-8.


Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).

Belinsky MG, Chen ZS, Shchaveleva I, Zeng H, Kruh GD.

Cancer Res. 2002 Nov 1;62(21):6172-7.


MRP subfamily transporters and resistance to anticancer agents.

Kruh GD, Zeng H, Rea PA, Liu G, Chen ZS, Lee K, Belinsky MG.

J Bioenerg Biomembr. 2001 Dec;33(6):493-501. Review.


Reversal of drug resistance mediated by multidrug resistance protein (MRP) 1 by dual effects of agosterol A on MRP1 function.

Chen ZS, Aoki S, Komatsu M, Ueda K, Sumizawa T, Furukawa T, Okumura H, Ren XQ, Belinsky MG, Lee K, Kruh GD, Kobayashi M, Akiyama S.

Int J Cancer. 2001 Jul 1;93(1):107-13.


Cloning and characterization of human adenosine 5'-triphosphate-binding cassette, sub-family A, transporter 2 (ABCA2).

Vulevic B, Chen Z, Boyd JT, Davis W Jr, Walsh ES, Belinsky MG, Tew KD.

Cancer Res. 2001 Apr 15;61(8):3339-47.


Analysis of the structure and expression pattern of MRP7 (ABCC10), a new member of the MRP subfamily.

Hopper E, Belinsky MG, Zeng H, Tosolini A, Testa JR, Kruh GD.

Cancer Lett. 2001 Jan 26;162(2):181-91.


Characterization of MOAT-C and MOAT-D, new members of the MRP/cMOAT subfamily of transporter proteins.

Belinsky MG, Bain LJ, Balsara BB, Testa JR, Kruh GD.

J Natl Cancer Inst. 1998 Nov 18;90(22):1735-41.


Amplification of the ATP-binding cassette 2 transporter gene is functionally linked with enhanced efflux of estramustine in ovarian carcinoma cells.

Laing NM, Belinsky MG, Kruh GD, Bell DW, Boyd JT, Barone L, Testa JR, Tew KD.

Cancer Res. 1998 Apr 1;58(7):1332-7.


Structure and in vitro substrate specificity of the murine multidrug resistance-associated protein.

Paul S, Belinsky MG, Shen H, Kruh GD.

Biochemistry. 1996 Oct 22;35(42):13647-55. Retraction in: Biochemistry. 1997 Nov 11;36(45):13972.


ARE- and TRE-mediated regulation of gene expression. Response to xenobiotics and antioxidants.

Xie T, Belinsky M, Xu Y, Jaiswal AK.

J Biol Chem. 1995 Mar 24;270(12):6894-900.


NAD(P)H:quinone oxidoreductase1 (DT-diaphorase) expression in normal and tumor tissues.

Belinsky M, Jaiswal AK.

Cancer Metastasis Rev. 1993 Jun;12(2):103-17. Review.


Self-cleavage of internally deleted hepatitis delta RNAs.

Belinsky M, Dinter-Gottlieb G.

Prog Clin Biol Res. 1993;382:89-97. No abstract available.


Modification interference analysis of a self-cleaving RNA from hepatitis delta virus.

Belinsky MG, Britton E, Dinter-Gottlieb G.

FASEB J. 1993 Jan;7(1):130-6.


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