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Alfvénic velocity spikes and rotational flows in the near-Sun solar wind.

Kasper JC, Bale SD, Belcher JW, Berthomier M, Case AW, Chandran BDG, Curtis DW, Gallagher D, Gary SP, Golub L, Halekas JS, Ho GC, Horbury TS, Hu Q, Huang J, Klein KG, Korreck KE, Larson DE, Livi R, Maruca B, Lavraud B, Louarn P, Maksimovic M, Martinovic M, McGinnis D, Pogorelov NV, Richardson JD, Skoug RM, Steinberg JT, Stevens ML, Szabo A, Velli M, Whittlesey PL, Wright KH, Zank GP, MacDowall RJ, McComas DJ, McNutt RL Jr, Pulupa M, Raouafi NE, Schwadron NA.

Nature. 2019 Dec;576(7786):228-231. doi: 10.1038/s41586-019-1813-z. Epub 2019 Dec 4.


Longitudinal clusters of pain and stiffness in polymyalgia rheumatica: 2-year results from the PMR Cohort Study.

Muller S, Whittle R, Hider SL, Belcher J, Helliwell T, Morton C, Hughes E, Lawton SA, Mallen CD.

Rheumatology (Oxford). 2019 Nov 19. pii: kez533. doi: 10.1093/rheumatology/kez533. [Epub ahead of print]


Characteristics of patients with giant cell arteritis who experience visual symptoms.

Chean CS, Prior JA, Helliwell T, Belcher J, Mackie SL, Hider SL, Liddle J, Mallen CD.

Rheumatol Int. 2019 Oct;39(10):1789-1796. doi: 10.1007/s00296-019-04422-5. Epub 2019 Aug 22.


Gender-specific risk factors for gout: a systematic review of cohort studies.

Evans PL, Prior JA, Belcher J, Hay CA, Mallen CD, Roddy E.

Adv Rheumatol. 2019 Jun 24;59(1):24. doi: 10.1186/s42358-019-0067-7.


Heme oxygenase-2 protects against ischemic acute kidney injury: influence of age and sex.

Nath KA, Garovic VD, Grande JP, Croatt AJ, Ackerman AW, Farrugia G, Katusic ZS, Belcher JD, Vercellotti GM.

Am J Physiol Renal Physiol. 2019 Sep 1;317(3):F695-F704. doi: 10.1152/ajprenal.00085.2019. Epub 2019 Jun 19.


A novel, highly potent and selective phosphodiesterase-9 inhibitor for the treatment of sickle cell disease.

McArthur JG, Svenstrup N, Chen C, Fricot A, Carvalho C, Nguyen J, Nguyen P, Prachikova A, Abdulla F, Vercellotti GM, Hermine O, Edwards D, Ribeil JA, Belcher JD, Maciel TT.

Haematologica. 2019 May 30. pii: haematol.2018.213462. doi: 10.3324/haematol.2018.213462. [Epub ahead of print]


Estimating risk of encapsulating peritoneal sclerosis accounting for the competing risk of death.

Lambie M, Teece L, Johnson DW, Petrie M, Mactier R, Solis-Trapala I, Belcher J, Bekker HL, Wilkie M, Tupling K, Phillips-Darby L, Davies SJ.

Nephrol Dial Transplant. 2019 Sep 1;34(9):1585-1591. doi: 10.1093/ndt/gfz034.


Critical role of C5a in sickle cell disease.

Vercellotti GM, Dalmasso AP, Schaid TR Jr, Nguyen J, Chen C, Ericson ME, Abdulla F, Killeen T, Lindorfer MA, Taylor RP, Belcher JD.

Am J Hematol. 2019 Mar;94(3):327-337. doi: 10.1002/ajh.25384. Epub 2019 Jan 3.


Hemoglobin oxidation-dependent reactions promote interactions with band 3 and oxidative changes in sickle cell-derived microparticles.

Jana S, Strader MB, Meng F, Hicks W, Kassa T, Tarandovskiy I, De Paoli S, Simak J, Heaven MR, Belcher JD, Vercellotti GM, Alayash AI.

JCI Insight. 2018 Nov 2;3(21). pii: 120451. doi: 10.1172/jci.insight.120451.


Risk of chronic kidney disease in patients with gout and the impact of urate lowering therapy: a population-based cohort study.

Roughley M, Sultan AA, Clarson L, Muller S, Whittle R, Belcher J, Mallen CD, Roddy E.

Arthritis Res Ther. 2018 Oct 30;20(1):243. doi: 10.1186/s13075-018-1746-1.


Oral carbon monoxide therapy in murine sickle cell disease: Beneficial effects on vaso-occlusion, inflammation and anemia.

Belcher JD, Gomperts E, Nguyen J, Chen C, Abdulla F, Kiser ZM, Gallo D, Levy H, Otterbein LE, Vercellotti GM.

PLoS One. 2018 Oct 11;13(10):e0205194. doi: 10.1371/journal.pone.0205194. eCollection 2018.


Serum haptoglobin and hemopexin levels are depleted in pediatric sickle cell disease patients.

Santiago RP, Guarda CC, Figueiredo CVB, Fiuza LM, Aleluia MM, Adanho CSA, Carvalho MOS, Pitanga TN, Zanette DL, Lyra IM, Nascimento VML, Vercellotti GM, Belcher JD, Goncalves MS.

Blood Cells Mol Dis. 2018 Sep;72:34-36. doi: 10.1016/j.bcmd.2018.07.002. Epub 2018 Jul 19. No abstract available.


Obesity, hypertension and diuretic use as risk factors for incident gout: a systematic review and meta-analysis of cohort studies.

Evans PL, Prior JA, Belcher J, Mallen CD, Hay CA, Roddy E.

Arthritis Res Ther. 2018 Jul 5;20(1):136. doi: 10.1186/s13075-018-1612-1.


Measurement error and timing of predictor values for multivariable risk prediction models are poorly reported.

Whittle R, Peat G, Belcher J, Collins GS, Riley RD.

J Clin Epidemiol. 2018 Oct;102:38-49. doi: 10.1016/j.jclinepi.2018.05.008. Epub 2018 May 18. Review.


Haptoglobin and hemopexin inhibit vaso-occlusion and inflammation in murine sickle cell disease: Role of heme oxygenase-1 induction.

Belcher JD, Chen C, Nguyen J, Abdulla F, Zhang P, Nguyen H, Nguyen P, Killeen T, Miescher SM, Brinkman N, Nath KA, Steer CJ, Vercellotti GM.

PLoS One. 2018 Apr 25;13(4):e0196455. doi: 10.1371/journal.pone.0196455. eCollection 2018.


Inflammation in sickle cell disease.

Conran N, Belcher JD.

Clin Hemorheol Microcirc. 2018;68(2-3):263-299. doi: 10.3233/CH-189012.


Cost-Utility Analysis of Routine Anxiety and Depression Screening in Patients Consulting for Osteoarthritis: Results From a Clinical, Randomized Controlled Trial.

Kigozi J, Jowett S, Nicholl BI, Lewis M, Bartlam B, Green D, Belcher J, Clarkson K, Lingard Z, Pope C, Chew-Graham CA, Croft P, Hay EM, Peat G, Mallen CD.

Arthritis Care Res (Hoboken). 2018 Dec;70(12):1787-1794. doi: 10.1002/acr.23568.


Bivalent ligand MCC22 potently attenuates nociception in a murine model of sickle cell disease.

Cataldo G, Lunzer MM, Olson JK, Akgün E, Belcher JD, Vercellotti GM, Portoghese PS, Simone DA.

Pain. 2018 Jul;159(7):1382-1391. doi: 10.1097/j.pain.0000000000001225.


Quantification of Urinary Protein Biomarkers of Autosomal Dominant Polycystic Kidney Disease by Parallel Reaction Monitoring.

Rauniyar N, Yu X, Cantley J, Voss EZ, Belcher J, Colangelo CM, Stone KL, Dahl N, Parikh C, Lam TT, Cantley LG.

Proteomics Clin Appl. 2018 Sep;12(5):e1700157. doi: 10.1002/prca.201700157. Epub 2018 May 2.


Case series supporting heme detoxification via therapeutic plasma exchange in acute multiorgan failure syndrome resistant to red blood cell exchange in sickle cell disease.

Louie JE, Anderson CJ, Fayaz M Fomani K, Henry A, Killeen T, Mohandas N, Yazdanbakhsh K, Belcher JD, Vercellotti GM, Shi PA.

Transfusion. 2018 Feb;58(2):470-479. doi: 10.1111/trf.14407. Epub 2017 Nov 27.


Factors Influencing Allopurinol Initiation in Primary Care.

Clarson LE, Hider SL, Belcher J, Roddy E, Mallen CD.

Ann Fam Med. 2017 Nov;15(6):557-560. doi: 10.1370/afm.2137.


Role of TLR4 signaling in the nephrotoxicity of heme and heme proteins.

Nath KA, Belcher JD, Nath MC, Grande JP, Croatt AJ, Ackerman AW, Katusic ZS, Vercellotti GM.

Am J Physiol Renal Physiol. 2018 May 1;314(5):F906-F914. doi: 10.1152/ajprenal.00432.2017. Epub 2017 Oct 4.


A monocyte-TNF-endothelial activation axis in sickle transgenic mice: Therapeutic benefit from TNF blockade.

Solovey A, Somani A, Belcher JD, Milbauer L, Vincent L, Pawlinski R, Nath KA, Kelm RJ Jr, Mackman N, O'Sullivan MG, Gupta K, Vercellotti GM, Hebbel RP.

Am J Hematol. 2017 Nov;92(11):1119-1130. doi: 10.1002/ajh.24856. Epub 2017 Jul 29.


Diagnostic delay for giant cell arteritis - a systematic review and meta-analysis.

Prior JA, Ranjbar H, Belcher J, Mackie SL, Helliwell T, Liddle J, Mallen CD.

BMC Med. 2017 Jun 28;15(1):120. doi: 10.1186/s12916-017-0871-z. Review.


How common is depression in patients with polymyalgia rheumatica?

Vivekanantham A, Blagojevic-Bucknall M, Clarkson K, Belcher J, Mallen CD, Hider SL.

Clin Rheumatol. 2018 Jun;37(6):1633-1638. doi: 10.1007/s10067-017-3691-9. Epub 2017 Jun 1.


Intergenerational Programs May Be Especially Engaging for Aged Care Residents With Cognitive Impairment: Findings From the Avondale Intergenerational Design Challenge.

Baker JR, Webster L, Lynn N, Rogers J, Belcher J.

Am J Alzheimers Dis Other Demen. 2017 Jun;32(4):213-221. doi: 10.1177/1533317517703477.


Endoplasmic reticulum (ER) Ca2+-channel activity contributes to ER stress and cone death in cyclic nucleotide-gated channel deficiency.

Butler MR, Ma H, Yang F, Belcher J, Le YZ, Mikoshiba K, Biel M, Michalakis S, Iuso A, Križaj D, Ding XQ.

J Biol Chem. 2017 Jul 7;292(27):11189-11205. doi: 10.1074/jbc.M117.782326. Epub 2017 May 11.


Public priorities for osteoporosis and fracture research: results from a general population survey.

Paskins Z, Jinks C, Mahmood W, Jayakumar P, Sangan CB, Belcher J, Gwilym S.

Arch Osteoporos. 2017 Dec;12(1):45. doi: 10.1007/s11657-017-0340-5. Epub 2017 Apr 28.


Inhibition of thyroid hormone receptor locally in the retina is a therapeutic strategy for retinal degeneration.

Ma H, Yang F, Butler MR, Belcher J, Redmond TM, Placzek AT, Scanlan TS, Ding XQ.

FASEB J. 2017 Aug;31(8):3425-3438. doi: 10.1096/fj.201601166RR. Epub 2017 Apr 20.


The effects of implementing a point-of-care electronic template to prompt routine anxiety and depression screening in patients consulting for osteoarthritis (the Primary Care Osteoarthritis Trial): A cluster randomised trial in primary care.

Mallen CD, Nicholl BI, Lewis M, Bartlam B, Green D, Jowett S, Kigozi J, Belcher J, Clarkson K, Lingard Z, Pope C, Chew-Graham CA, Croft P, Hay EM, Peat G.

PLoS Med. 2017 Apr 11;14(4):e1002273. doi: 10.1371/journal.pmed.1002273. eCollection 2017 Apr.


The role of carbon monoxide and heme oxygenase in the prevention of sickle cell disease vaso-occlusive crises.

Gomperts E, Belcher JD, Otterbein LE, Coates TD, Wood J, Skolnick BE, Levy H, Vercellotti GM.

Am J Hematol. 2017 Jun;92(6):569-582. doi: 10.1002/ajh.24750. Epub 2017 Apr 29. Review.


Use of a Targeted Urine Proteome Assay (TUPA) to identify protein biomarkers of delayed recovery after kidney transplant.

Williams KR, Colangelo CM, Hou L, Chung L, Belcher JM, Abbott T, Hall IE, Zhao H, Cantley LG, Parikh CR.

Proteomics Clin Appl. 2017 Jul;11(7-8). doi: 10.1002/prca.201600132. Epub 2017 Mar 31.


Targeting Access to Kidney Care Via Telehealth: The VA Experience.

Crowley ST, Belcher J, Choudhury D, Griffin C, Pichler R, Robey B, Rohatgi R, Mielcarek B.

Adv Chronic Kidney Dis. 2017 Jan;24(1):22-30. doi: 10.1053/j.ackd.2016.11.005. Review.


Catalytic Determinants of Alkene Production by the Cytochrome P450 Peroxygenase OleTJE.

Matthews S, Belcher JD, Tee KL, Girvan HM, McLean KJ, Rigby SE, Levy CW, Leys D, Parker DA, Blankley RT, Munro AW.

J Biol Chem. 2017 Mar 24;292(12):5128-5143. doi: 10.1074/jbc.M116.762336. Epub 2017 Jan 4.


Urine Interleukin 18 and Lipocalin 2 Are Biomarkers of Acute Tubular Necrosis in Patients With Cirrhosis: A Systematic Review and Meta-analysis.

Puthumana J, Ariza X, Belcher JM, Graupera I, Ginès P, Parikh CR.

Clin Gastroenterol Hepatol. 2017 Jul;15(7):1003-1013.e3. doi: 10.1016/j.cgh.2016.11.035. Epub 2016 Dec 21. Review.


Exhaled breath hydrogen cyanide as a marker of early Pseudomonas aeruginosa infection in children with cystic fibrosis.

Gilchrist FJ, Belcher J, Jones AM, Smith D, Smyth AR, Southern KW, Španěl P, Webb AK, Lenney W.

ERJ Open Res. 2015 Nov 16;1(2). pii: 00044-2015. eCollection 2015 Oct.


Clinical Significance of Medial Versus Lateral Compartment Patellofemoral Osteoarthritis: Cross-Sectional Analyses in an Adult Population With Knee Pain.

Ukachukwu V, Duncan R, Belcher J, Marshall M, Stefanik J, Crossley K, Thomas MJ, Peat G.

Arthritis Care Res (Hoboken). 2017 Jul;69(7):943-951. doi: 10.1002/acr.23110.


Illness perceptions of gout patients and the use of allopurinol in primary care: baseline findings from a prospective cohort study.

Walsh CP, Prior JA, Chandratre P, Belcher J, Mallen CD, Roddy E.

BMC Musculoskelet Disord. 2016 Sep 17;17(1):394. doi: 10.1186/s12891-016-1252-z.


Targeting iodothyronine deiodinases locally in the retina is a therapeutic strategy for retinal degeneration.

Yang F, Ma H, Belcher J, Butler MR, Redmond TM, Boye SL, Hauswirth WW, Ding XQ.

FASEB J. 2016 Dec;30(12):4313-4325. Epub 2016 Sep 13.


A Genome-Wide Association Study to Identify Single-Nucleotide Polymorphisms for Acute Kidney Injury.

Zhao B, Lu Q, Cheng Y, Belcher JM, Siew ED, Leaf DE, Body SC, Fox AA, Waikar SS, Collard CD, Thiessen-Philbrook H, Ikizler TA, Ware LB, Edelstein CL, Garg AX, Choi M, Schaub JA, Zhao H, Lifton RP, Parikh CR; TRIBE-AKI Consortium * .

Am J Respir Crit Care Med. 2017 Feb 15;195(4):482-490. doi: 10.1164/rccm.201603-0518OC.


Sustained treatment of sickle cell mice with haptoglobin increases HO-1 and H-ferritin expression and decreases iron deposition in the kidney without improvement in kidney function.

Shi PA, Choi E, Chintagari NR, Nguyen J, Guo X, Yazdanbakhsh K, Mohandas N, Alayash AI, Manci EA, Belcher JD, Vercellotti GM.

Br J Haematol. 2016 Nov;175(4):714-723. doi: 10.1111/bjh.14280. Epub 2016 Aug 10.


Widespread pain and depression are key modifiable risk factors associated with reduced social participation in older adults: A prospective cohort study in primary care.

Wilkie R, Blagojevic-Bucknall M, Belcher J, Chew-Graham C, Lacey RJ, McBeth J.

Medicine (Baltimore). 2016 Aug;95(31):e4111. doi: 10.1097/MD.0000000000004111.


Hepatic Overexpression of Hemopexin Inhibits Inflammation and Vascular Stasis in Murine Models of Sickle Cell Disease.

Vercellotti GM, Zhang P, Nguyen J, Abdulla F, Chen C, Nguyen P, Nowotny C, Steer CJ, Smith A, Belcher JD.

Mol Med. 2016 Sep;22:437-451. doi: 10.2119/molmed.2016.00063. Epub 2016 Jul 19.


Symptom Recognition and Perceived Urgency of Help-Seeking for Rheumatoid Arthritis and Other Diseases in the General Public: A Mixed Method Approach.

Simons G, Belcher J, Morton C, Kumar K, Falahee M, Mallen CD, Stack RJ, Raza K.

Arthritis Care Res (Hoboken). 2017 May;69(5):633-641. doi: 10.1002/acr.22979. Epub 2017 Apr 10.


Control of Oxidative Stress and Inflammation in Sickle Cell Disease with the Nrf2 Activator Dimethyl Fumarate.

Belcher JD, Chen C, Nguyen J, Zhang P, Abdulla F, Nguyen P, Killeen T, Xu P, O'Sullivan G, Nath KA, Vercellotti GM.

Antioxid Redox Signal. 2017 May 10;26(14):748-762. doi: 10.1089/ars.2015.6571. Epub 2016 Mar 30.


Evaluating three hundred and fifty-two admissions and predictors of re-admissions for epistaxis - is it time to re-evaluate tranexamic acid in epistaxis?

Jervis S, Saunders T, Belcher J, Skinner D.

Clin Otolaryngol. 2017 Apr;42(2):439-442. doi: 10.1111/coa.12609. Epub 2016 Feb 18. No abstract available.


Clustering of pain and its associations with health in people aged 50 years and older: cross-sectional results from the North Staffordshire Osteoarthritis Project.

Lacey RJ, Strauss VY, Rathod T, Belcher J, Croft PR, Natvig B, Wilkie R, McBeth J.

BMJ Open. 2015 Nov 9;5(11):e008389. doi: 10.1136/bmjopen-2015-008389.


Acute Kidney Injury in Liver Disease: Role of Biomarkers.

Belcher JM.

Adv Chronic Kidney Dis. 2015 Sep;22(5):368-75. doi: 10.1053/j.ackd.2015.06.009. Review.


Creatinine Change on Vasoconstrictors as Mortality Surrogate in Hepatorenal Syndrome: Systematic Review & Meta-Analysis.

Belcher JM, Coca SG, Parikh CR.

PLoS One. 2015 Aug 21;10(8):e0135625. doi: 10.1371/journal.pone.0135625. eCollection 2015. Review.


Development of a Targeted Urine Proteome Assay for kidney diseases.

Cantley LG, Colangelo CM, Stone KL, Chung L, Belcher J, Abbott T, Cantley JL, Williams KR, Parikh CR.

Proteomics Clin Appl. 2016 Jan;10(1):58-74. doi: 10.1002/prca.201500020. Epub 2015 Oct 6.

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