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Items: 40


Crystal structure and epitope analysis of house dust mite allergen Der f 21.

Pang SL, Ho KL, Waterman J, Rambo RP, Teh AH, Mathavan I, Harris G, Beis K, Say YH, Anusha MS, Sio YY, Chew FT, Ng CL.

Sci Rep. 2019 Mar 20;9(1):4933. doi: 10.1038/s41598-019-40879-x.


Solid immersion microscopy images cells under cryogenic conditions with 12 nm resolution.

Wang L, Bateman B, Zanetti-Domingues LC, Moores AN, Astbury S, Spindloe C, Darrow MC, Romano M, Needham SR, Beis K, Rolfe DJ, Clarke DT, Martin-Fernandez ML.

Commun Biol. 2019 Feb 21;2:74. doi: 10.1038/s42003-019-0317-6. eCollection 2019.


Learning the ABCs one at a time: structure and mechanism of ABC transporters.

Ford RC, Beis K.

Biochem Soc Trans. 2019 Feb 28;47(1):23-36. doi: 10.1042/BST20180147. Epub 2019 Jan 9. Review.


Conformational dynamics of the ABC transporter McjD seen by single-molecule FRET.

Husada F, Bountra K, Tassis K, de Boer M, Romano M, Rebuffat S, Beis K, Cordes T.

EMBO J. 2018 Nov 2;37(21). pii: e100056. doi: 10.15252/embj.2018100056. Epub 2018 Sep 20.


Structural Basis for Natural Product Selection and Export by Bacterial ABC Transporters.

Romano M, Fusco G, Choudhury HG, Mehmood S, Robinson CV, Zirah S, Hegemann JD, Lescop E, Marahiel MA, Rebuffat S, De Simone A, Beis K.

ACS Chem Biol. 2018 Jun 15;13(6):1598-1609. doi: 10.1021/acschembio.8b00226. Epub 2018 May 18.


Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site.

Wahlgren WY, Dunevall E, North RA, Paz A, Scalise M, Bisignano P, Bengtsson-Palme J, Goyal P, Claesson E, Caing-Carlsson R, Andersson R, Beis K, Nilsson UJ, Farewell A, Pochini L, Indiveri C, Grabe M, Dobson RCJ, Abramson J, Ramaswamy S, Friemann R.

Nat Commun. 2018 May 1;9(1):1753. doi: 10.1038/s41467-018-04045-7.


Structural basis for antibacterial peptide self-immunity by the bacterial ABC transporter McjD.

Bountra K, Hagelueken G, Choudhury HG, Corradi V, El Omari K, Wagner A, Mathavan I, Zirah S, Yuan Wahlgren W, Tieleman DP, Schiemann O, Rebuffat S, Beis K.

EMBO J. 2017 Oct 16;36(20):3062-3079. doi: 10.15252/embj.201797278. Epub 2017 Sep 1.


Structural and Functional Basis for Lipid Synergy on the Activity of the Antibacterial Peptide ABC Transporter McjD.

Mehmood S, Corradi V, Choudhury HG, Hussain R, Becker P, Axford D, Zirah S, Rebuffat S, Tieleman DP, Robinson CV, Beis K.

J Biol Chem. 2016 Oct 7;291(41):21656-21668. Epub 2016 Aug 23.


Structural basis for the mechanism of ABC transporters.

Beis K.

Biochem Soc Trans. 2015 Oct;43(5):889-93. doi: 10.1042/BST20150047. Review.


Conformational Changes of the Antibacterial Peptide ATP Binding Cassette Transporter McjD Revealed by Molecular Dynamics Simulations.

Gu RX, Corradi V, Singh G, Choudhury HG, Beis K, Tieleman DP.

Biochemistry. 2015 Sep 29;54(38):5989-98. doi: 10.1021/acs.biochem.5b00753. Epub 2015 Sep 17.


Structure determination of an integral membrane protein at room temperature from crystals in situ.

Axford D, Foadi J, Hu NJ, Choudhury HG, Iwata S, Beis K, Evans G, Alguel Y.

Acta Crystallogr D Biol Crystallogr. 2015 Jun;71(Pt 6):1228-37. doi: 10.1107/S139900471500423X. Epub 2015 May 14.


MemStar: a one-shot Escherichia coli-based approach for high-level bacterial membrane protein production.

Lee C, Kang HJ, Hjelm A, Qureshi AA, Nji E, Choudhury H, Beis K, de Gier JW, Drew D.

FEBS Lett. 2014 Oct 16;588(20):3761-9. doi: 10.1016/j.febslet.2014.08.025. Epub 2014 Aug 28.


Structure of an antibacterial peptide ATP-binding cassette transporter in a novel outward occluded state.

Choudhury HG, Tong Z, Mathavan I, Li Y, Iwata S, Zirah S, Rebuffat S, van Veen HW, Beis K.

Proc Natl Acad Sci U S A. 2014 Jun 24;111(25):9145-50. doi: 10.1073/pnas.1320506111. Epub 2014 Jun 11.


Structural basis for hijacking siderophore receptors by antimicrobial lasso peptides.

Mathavan I, Zirah S, Mehmood S, Choudhury HG, Goulard C, Li Y, Robinson CV, Rebuffat S, Beis K.

Nat Chem Biol. 2014 May;10(5):340-2. doi: 10.1038/nchembio.1499. Epub 2014 Apr 6.


Functional and structural study of the dimeric inner membrane protein SbmA.

Corbalan N, Runti G, Adler C, Covaceuszach S, Ford RC, Lamba D, Beis K, Scocchi M, Vincent PA.

J Bacteriol. 2013 Dec;195(23):5352-61. doi: 10.1128/JB.00824-13. Epub 2013 Sep 27.


Functional characterization of SbmA, a bacterial inner membrane transporter required for importing the antimicrobial peptide Bac7(1-35).

Runti G, Lopez Ruiz Mdel C, Stoilova T, Hussain R, Jennions M, Choudhury HG, Benincasa M, Gennaro R, Beis K, Scocchi M.

J Bacteriol. 2013 Dec;195(23):5343-51. doi: 10.1128/JB.00818-13. Epub 2013 Sep 27.


The dimeric form of the unphosphorylated response regulator BaeR.

Choudhury HG, Beis K.

Protein Sci. 2013 Sep;22(9):1287-93. doi: 10.1002/pro.2311. Epub 2013 Aug 12.


The role of bacterial membrane proteins in the internalization of microcin MccJ25 and MccB17.

Mathavan I, Beis K.

Biochem Soc Trans. 2012 Dec 1;40(6):1539-43. doi: 10.1042/BST20120176. Review.


Altered antibiotic transport in OmpC mutants isolated from a series of clinical strains of multi-drug resistant E. coli.

Lou H, Chen M, Black SS, Bushell SR, Ceccarelli M, Mach T, Beis K, Low AS, Bamford VA, Booth IR, Bayley H, Naismith JH.

PLoS One. 2011;6(10):e25825. doi: 10.1371/journal.pone.0025825. Epub 2011 Oct 28.


Structure and mechanism of the chalcogen-detoxifying protein TehB from Escherichia coli.

Choudhury HG, Cameron AD, Iwata S, Beis K.

Biochem J. 2011 Apr 1;435(1):85-91. doi: 10.1042/BJ20102014.


Benchmarking membrane protein detergent stability for improving throughput of high-resolution X-ray structures.

Sonoda Y, Newstead S, Hu NJ, Alguel Y, Nji E, Beis K, Yashiro S, Lee C, Leung J, Cameron AD, Byrne B, Iwata S, Drew D.

Structure. 2011 Jan 12;19(1):17-25. doi: 10.1016/j.str.2010.12.001.


Crystallization and preliminary diffraction analysis of Wzi, a member of the capsule export and assembly pathway in Escherichia coli.

Bushell SR, Lou H, Wallat GD, Beis K, Whitfield C, Naismith JH.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Dec 1;66(Pt 12):1621-5. doi: 10.1107/S1744309110040546. Epub 2010 Nov 26.


Crystallization and initial X-ray diffraction analysis of the tellurite-resistance S-adenosyl-L-methionine transferase protein TehB from Escherichia coli.

Choudhury HG, Beis K.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Nov 1;66(Pt 11):1496-9. doi: 10.1107/S1744309110036043. Epub 2010 Oct 28.


Structure of the aliphatic sulfonate-binding protein SsuA from Escherichia coli.

Beale J, Lee SY, Iwata S, Beis K.

Acta Crystallogr Sect F Struct Biol Cryst Commun. 2010 Apr 1;66(Pt 4):391-6. doi: 10.1107/S1744309110006226. Epub 2010 Mar 26.


The structure of the efflux pump AcrB in complex with bile acid.

Drew D, Klepsch MM, Newstead S, Flaig R, De Gier JW, Iwata S, Beis K.

Mol Membr Biol. 2008 Dec;25(8):677-82. doi: 10.1080/09687680802552257.


Overcoming the challenges of membrane protein crystallography.

Carpenter EP, Beis K, Cameron AD, Iwata S.

Curr Opin Struct Biol. 2008 Oct;18(5):581-6. doi: 10.1016/ Epub 2008 Aug 11. Review.


The 3D structure of a periplasm-spanning platform required for assembly of group 1 capsular polysaccharides in Escherichia coli.

Collins RF, Beis K, Dong C, Botting CH, McDonnell C, Ford RC, Clarke BR, Whitfield C, Naismith JH.

Proc Natl Acad Sci U S A. 2007 Feb 13;104(7):2390-5. Epub 2007 Feb 5.


Taekwondo techniques and competition characteristics involved in time-loss injuries.

Beis K, Pieter W, Abatzides G.

J Sports Sci Med. 2007 Oct 1;6(CSSI-2):45-51. eCollection 2007.


Wza the translocon for E. coli capsular polysaccharides defines a new class of membrane protein.

Dong C, Beis K, Nesper J, Brunkan-Lamontagne AL, Clarke BR, Whitfield C, Naismith JH.

Nature. 2006 Nov 9;444(7116):226-9. Epub 2006 Nov 1.


Two-step purification of outer membrane proteins.

Beis K, Whitfield C, Booth I, Naismith JH.

Int J Biol Macromol. 2006 Aug 15;39(1-3):10-4. Epub 2006 Jan 19.


Periplasmic protein-protein contacts in the inner membrane protein Wzc form a tetrameric complex required for the assembly of Escherichia coli group 1 capsules.

Collins RF, Beis K, Clarke BR, Ford RC, Hulley M, Naismith JH, Whitfield C.

J Biol Chem. 2006 Jan 27;281(4):2144-50. Epub 2005 Sep 19.


Crystal structures of Mycobacteria tuberculosis and Klebsiella pneumoniae UDP-galactopyranose mutase in the oxidised state and Klebsiella pneumoniae UDP-galactopyranose mutase in the (active) reduced state.

Beis K, Srikannathasan V, Liu H, Fullerton SW, Bamford VA, Sanders DA, Whitfield C, McNeil MR, Naismith JH.

J Mol Biol. 2005 May 13;348(4):971-82.


Three-dimensional structure of Wza, the protein required for translocation of group 1 capsular polysaccharide across the outer membrane of Escherichia coli.

Beis K, Collins RF, Ford RC, Kamis AB, Whitfield C, Naismith JH.

J Biol Chem. 2004 Jul 2;279(27):28227-32. Epub 2004 Apr 16.


Crystallization and preliminary X-ray diffraction analysis of Wza outer-membrane lipoprotein from Escherichia coli serotype O9a:K30.

Beis K, Nesper J, Whitfield C, Naismith JH.

Acta Crystallogr D Biol Crystallogr. 2004 Mar;60(Pt 3):558-60. Epub 2004 Feb 25.


Translocation of group 1 capsular polysaccharide in Escherichia coli serotype K30. Structural and functional analysis of the outer membrane lipoprotein Wza.

Nesper J, Hill CM, Paiment A, Harauz G, Beis K, Naismith JH, Whitfield C.

J Biol Chem. 2003 Dec 12;278(50):49763-72. Epub 2003 Sep 30.


The structure of NADH in the enzyme dTDP-d-glucose dehydratase (RmlB).

Beis K, Allard ST, Hegeman AD, Murshudov G, Philp D, Naismith JH.

J Am Chem Soc. 2003 Oct 1;125(39):11872-8.


A structural perspective on the enzymes that convert dTDP-d-glucose into dTDP-l-rhamnose.

Dong C, Beis K, Giraud MF, Blankenfeldt W, Allard S, Major LL, Kerr ID, Whitfield C, Naismith JH.

Biochem Soc Trans. 2003 Jun;31(Pt 3):532-6. Review.


Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway.

Merkel AB, Temple GK, Burkart MD, Losey HC, Beis K, Walsh CT, Naismith JH.

Acta Crystallogr D Biol Crystallogr. 2002 Jul;58(Pt 7):1226-8. Epub 2002 Jun 20.


Toward a structural understanding of the dehydratase mechanism.

Allard ST, Beis K, Giraud MF, Hegeman AD, Gross JW, Wilmouth RC, Whitfield C, Graninger M, Messner P, Allen AG, Maskell DJ, Naismith JH.

Structure. 2002 Jan;10(1):81-92.

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