Sort by
Items per page

Send to

Choose Destination

Search results

Items: 44


3'-UTRs and the Control of Protein Expression in Space and Time.

Beilharz TH, See MM, Boag PR.

Adv Exp Med Biol. 2019;1203:133-148. doi: 10.1007/978-3-030-31434-7_5.


PAT-Seq: A Method for Simultaneous Quantitation of Gene Expression, Poly(A)-Site Selection and Poly(A)-Length Distribution in Yeast Transcriptomes.

Swaminathan A, Harrison PF, Preiss T, Beilharz TH.

Methods Mol Biol. 2019;2049:141-164. doi: 10.1007/978-1-4939-9736-7_9.


Topconfects: a package for confident effect sizes in differential expression analysis provides a more biologically useful ranked gene list.

Harrison PF, Pattison AD, Powell DR, Beilharz TH.

Genome Biol. 2019 Mar 28;20(1):67. doi: 10.1186/s13059-019-1674-7.


A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling.

Koch B, Barugahare AA, Lo TL, Huang C, Schittenhelm RB, Powell DR, Beilharz TH, Traven A.

Cell Rep. 2018 Nov 20;25(8):2244-2258.e7. doi: 10.1016/j.celrep.2018.10.080.


SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program.

Ratnadiwakara M, Archer SK, Dent CI, Ruiz De Los Mozos I, Beilharz TH, Knaupp AS, Nefzger CM, Polo JM, Anko ML.

Elife. 2018 May 9;7. pii: e37419. doi: 10.7554/eLife.37419.


Functional and genomic characterisation of a xenograft model system for the study of metastasis in triple-negative breast cancer.

Johnstone CN, Pattison AD, Gorringe KL, Harrison PF, Powell DR, Lock P, Baloyan D, Ernst M, Stewart AG, Beilharz TH, Anderson RL.

Dis Model Mech. 2018 May 29;11(5). pii: dmm032250. doi: 10.1242/dmm.032250.


Glucose Homeostasis Is Important for Immune Cell Viability during Candida Challenge and Host Survival of Systemic Fungal Infection.

Tucey TM, Verma J, Harrison PF, Snelgrove SL, Lo TL, Scherer AK, Barugahare AA, Powell DR, Wheeler RT, Hickey MJ, Beilharz TH, Naderer T, Traven A.

Cell Metab. 2018 May 1;27(5):988-1006.e7. doi: 10.1016/j.cmet.2018.03.019.


miR-222 isoforms are differentially regulated by type-I interferon.

Nejad C, Pillman KA, Siddle KJ, Pépin G, Änkö ML, McCoy CE, Beilharz TH, Quintana-Murci L, Goodall GJ, Bracken CP, Gantier MP.

RNA. 2018 Mar;24(3):332-341. doi: 10.1261/rna.064550.117. Epub 2017 Dec 20.


piRNAs and Aubergine cooperate with Wispy poly(A) polymerase to stabilize mRNAs in the germ plasm.

Dufourt J, Bontonou G, Chartier A, Jahan C, Meunier AC, Pierson S, Harrison PF, Papin C, Beilharz TH, Simonelig M.

Nat Commun. 2017 Nov 3;8(1):1305. doi: 10.1038/s41467-017-01431-5.


Alternative polyadenylation in the regulation and dysregulation of gene expression.

Turner RE, Pattison AD, Beilharz TH.

Semin Cell Dev Biol. 2018 Mar;75:61-69. doi: 10.1016/j.semcdb.2017.08.056. Epub 2017 Sep 1. Review.


LIN-41 and OMA Ribonucleoprotein Complexes Mediate a Translational Repression-to-Activation Switch Controlling Oocyte Meiotic Maturation and the Oocyte-to-Embryo Transition in Caenorhabditis elegans.

Tsukamoto T, Gearhart MD, Spike CA, Huelgas-Morales G, Mews M, Boag PR, Beilharz TH, Greenstein D.

Genetics. 2017 Aug;206(4):2007-2039. doi: 10.1534/genetics.117.203174. Epub 2017 Jun 1.


Translation complex profile sequencing to study the in vivo dynamics of mRNA-ribosome interactions during translation initiation, elongation and termination.

Shirokikh NE, Archer SK, Beilharz TH, Powell D, Preiss T.

Nat Protoc. 2017 Apr;12(4):697-731. doi: 10.1038/nprot.2016.189. Epub 2017 Mar 2.


Coordination of Cell Cycle Progression and Mitotic Spindle Assembly Involves Histone H3 Lysine 4 Methylation by Set1/COMPASS.

Beilharz TH, Harrison PF, Miles DM, See MM, Le UM, Kalanon M, Curtis MJ, Hasan Q, Saksouk J, Margaritis T, Holstege F, Geli V, Dichtl B.

Genetics. 2017 Jan;205(1):185-199. doi: 10.1534/genetics.116.194852. Epub 2016 Nov 14.


Accessory subunits are integral for assembly and function of human mitochondrial complex I.

Stroud DA, Surgenor EE, Formosa LE, Reljic B, Frazier AE, Dibley MG, Osellame LD, Stait T, Beilharz TH, Thorburn DR, Salim A, Ryan MT.

Nature. 2016 Oct 6;538(7623):123-126. doi: 10.1038/nature19754. Epub 2016 Sep 14.


Dynamics of ribosome scanning and recycling revealed by translation complex profiling.

Archer SK, Shirokikh NE, Beilharz TH, Preiss T.

Nature. 2016 Jul 28;535(7613):570-4. Epub 2016 Jul 20.


Role of miRNAs and alternative mRNA 3'-end cleavage and polyadenylation of their mRNA targets in cardiomyocyte hypertrophy.

Soetanto R, Hynes CJ, Patel HR, Humphreys DT, Evers M, Duan G, Parker BJ, Archer SK, Clancy JL, Graham RM, Beilharz TH, Smith NJ, Preiss T.

Biochim Biophys Acta. 2016 May;1859(5):744-56. doi: 10.1016/j.bbagrm.2016.03.010. Epub 2016 Mar 24.


Understanding the regulation of coding and noncoding transcription in cell populations.

Beilharz TH.

Curr Genet. 2016 May;62(2):317-9. doi: 10.1007/s00294-015-0547-1. Epub 2015 Dec 11. Review.


Epitope-tagged yeast strains reveal promoter driven changes to 3'-end formation and convergent antisense-transcription from common 3' UTRs.

Swaminathan A, Beilharz TH.

Nucleic Acids Res. 2016 Jan 8;44(1):377-86. doi: 10.1093/nar/gkv1022. Epub 2015 Oct 19.


Integration of Posttranscriptional Gene Networks into Metabolic Adaptation and Biofilm Maturation in Candida albicans.

Verma-Gaur J, Qu Y, Harrison PF, Lo TL, Quenault T, Dagley MJ, Bellousoff M, Powell DR, Beilharz TH, Traven A.

PLoS Genet. 2015 Oct 16;11(10):e1005590. doi: 10.1371/journal.pgen.1005590. eCollection 2015 Oct.


POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA.

Elewa A, Shirayama M, Kaymak E, Harrison PF, Powell DR, Du Z, Chute CD, Woolf H, Yi D, Ishidate T, Srinivasan J, Bao Z, Beilharz TH, Ryder SP, Mello CC.

Dev Cell. 2015 Jul 6;34(1):108-18. doi: 10.1016/j.devcel.2015.05.024. Epub 2015 Jun 18.


PAT-seq: a method to study the integration of 3'-UTR dynamics with gene expression in the eukaryotic transcriptome.

Harrison PF, Powell DR, Clancy JL, Preiss T, Boag PR, Traven A, Seemann T, Beilharz TH.

RNA. 2015 Aug;21(8):1502-10. doi: 10.1261/rna.048355.114. Epub 2015 Jun 19.


Probing the closed-loop model of mRNA translation in living cells.

Archer SK, Shirokikh NE, Hallwirth CV, Beilharz TH, Preiss T.

RNA Biol. 2015;12(3):248-54. doi: 10.1080/15476286.2015.1017242.


Using Klenow-mediated extension to measure poly(A)-tail length and position in the transcriptome.

Lee MC, Jänicke A, Beilharz TH.

Methods Mol Biol. 2014;1125:25-42. doi: 10.1007/978-1-62703-971-0_3.


Introns regulate gene expression in Cryptococcus neoformans in a Pab2p dependent pathway.

Goebels C, Thonn A, Gonzalez-Hilarion S, Rolland O, Moyrand F, Beilharz TH, Janbon G.

PLoS Genet. 2013;9(8):e1003686. doi: 10.1371/journal.pgen.1003686. Epub 2013 Aug 15.


ifet-1 is a broad-scale translational repressor required for normal P granule formation in C. elegans.

Sengupta MS, Low WY, Patterson JR, Kim HM, Traven A, Beilharz TH, Colaiácovo MP, Schisa JA, Boag PR.

J Cell Sci. 2013 Feb 1;126(Pt 3):850-9. doi: 10.1242/jcs.119834. Epub 2012 Dec 21.


A model system for mitochondrial biogenesis reveals evolutionary rewiring of protein import and membrane assembly pathways.

Hewitt VL, Heinz E, Shingu-Vazquez M, Qu Y, Jelicic B, Lo TL, Beilharz TH, Dumsday G, Gabriel K, Traven A, Lithgow T.

Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):E3358-66. doi: 10.1073/pnas.1206345109. Epub 2012 Nov 14.


Transcriptional profiling of a yeast colony provides new insight into the heterogeneity of multicellular fungal communities.

Traven A, Jänicke A, Harrison P, Swaminathan A, Seemann T, Beilharz TH.

PLoS One. 2012;7(9):e46243. doi: 10.1371/journal.pone.0046243. Epub 2012 Sep 28.


The mRNA decay pathway regulates the expression of the Flo11 adhesin and biofilm formation in Saccharomyces cerevisiae.

Lo TL, Qu Y, Uwamahoro N, Quenault T, Beilharz TH, Traven A.

Genetics. 2012 Aug;191(4):1387-91. doi: 10.1534/genetics.112.141432. Epub 2012 May 17.


ePAT: a simple method to tag adenylated RNA to measure poly(A)-tail length and other 3' RACE applications.

Jänicke A, Vancuylenberg J, Boag PR, Traven A, Beilharz TH.

RNA. 2012 Jun;18(6):1289-95. doi: 10.1261/rna.031898.111. Epub 2012 Apr 27.


The functions of Mediator in Candida albicans support a role in shaping species-specific gene expression.

Uwamahoro N, Qu Y, Jelicic B, Lo TL, Beaurepaire C, Bantun F, Quenault T, Boag PR, Ramm G, Callaghan J, Beilharz TH, Nantel A, Peleg AY, Traven A.

PLoS Genet. 2012;8(4):e1002613. doi: 10.1371/journal.pgen.1002613. Epub 2012 Apr 5.


Mitochondrial sorting and assembly machinery subunit Sam37 in Candida albicans: insight into the roles of mitochondria in fitness, cell wall integrity, and virulence.

Qu Y, Jelicic B, Pettolino F, Perry A, Lo TL, Hewitt VL, Bantun F, Beilharz TH, Peleg AY, Lithgow T, Djordjevic JT, Traven A.

Eukaryot Cell. 2012 Apr;11(4):532-44. doi: 10.1128/EC.05292-11. Epub 2012 Jan 27.


Polyadenylation state microarray (PASTA) analysis.

Beilharz TH, Preiss T.

Methods Mol Biol. 2011;759:133-48. doi: 10.1007/978-1-61779-173-4_9.


mRNA isoform diversity can obscure detection of miRNA-mediated control of translation.

Clancy JL, Wei GH, Echner N, Humphreys DT, Beilharz TH, Preiss T.

RNA. 2011 Jun;17(6):1025-31. doi: 10.1261/rna.2567611. Epub 2011 Apr 5.


Cell wall integrity is linked to mitochondria and phospholipid homeostasis in Candida albicans through the activity of the post-transcriptional regulator Ccr4-Pop2.

Dagley MJ, Gentle IE, Beilharz TH, Pettolino FA, Djordjevic JT, Lo TL, Uwamahoro N, Rupasinghe T, Tull DL, McConville M, Beaurepaire C, Nantel A, Lithgow T, Mitchell AP, Traven A.

Mol Microbiol. 2011 Feb;79(4):968-89. doi: 10.1111/j.1365-2958.2010.07503.x. Epub 2010 Dec 30.


miRNA Effects on mRNA closed-loop formation during translation initiation.

Beilharz TH, Humphreys DT, Preiss T.

Prog Mol Subcell Biol. 2010;50:99-112. doi: 10.1007/978-3-642-03103-8_7. Review.


microRNA-mediated messenger RNA deadenylation contributes to translational repression in mammalian cells.

Beilharz TH, Humphreys DT, Clancy JL, Thermann R, Martin DI, Hentze MW, Preiss T.

PLoS One. 2009 Aug 27;4(8):e6783. doi: 10.1371/journal.pone.0006783.


The Ccr4-Pop2-NOT mRNA deadenylase contributes to septin organization in Saccharomyces cerevisiae.

Traven A, Beilharz TH, Lo TL, Lueder F, Preiss T, Heierhorst J.

Genetics. 2009 Aug;182(4):955-66. doi: 10.1534/genetics.109.104414. Epub 2009 Jun 1.


Transcriptome-wide measurement of mRNA polyadenylation state.

Beilharz TH, Preiss T.

Methods. 2009 Jul;48(3):294-300. doi: 10.1016/j.ymeth.2009.02.003. Epub 2009 Feb 20.


Methods to analyze microRNA-mediated control of mRNA translation.

Clancy JL, Nousch M, Humphreys DT, Westman BJ, Beilharz TH, Preiss T.

Methods Enzymol. 2007;431:83-111. Review.


A network of multiple regulatory layers shapes gene expression in fission yeast.

Lackner DH, Beilharz TH, Marguerat S, Mata J, Watt S, Schubert F, Preiss T, Bähler J.

Mol Cell. 2007 Apr 13;26(1):145-55.


Ccr4 contributes to tolerance of replication stress through control of CRT1 mRNA poly(A) tail length.

Woolstencroft RN, Beilharz TH, Cook MA, Preiss T, Durocher D, Tyers M.

J Cell Sci. 2006 Dec 15;119(Pt 24):5178-92.


Translational profiling: the genome-wide measure of the nascent proteome.

Beilharz TH, Preiss T.

Brief Funct Genomic Proteomic. 2004 Aug;3(2):103-11. Review.


Multiple cargo binding sites on the COPII subunit Sec24p ensure capture of diverse membrane proteins into transport vesicles.

Miller EA, Beilharz TH, Malkus PN, Lee MC, Hamamoto S, Orci L, Schekman R.

Cell. 2003 Aug 22;114(4):497-509.

Supplemental Content

Loading ...
Support Center