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Items: 1 to 50 of 56

1.

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells.

Liu Y, Bao C, Wang L, Han R, Beier UH, Akimova T, Cole PA, Dent SYR, Hancock WW.

Cancers (Basel). 2019 Apr 18;11(4). pii: E554. doi: 10.3390/cancers11040554.

2.

Human tumor-associated monocytes/macrophages and their regulation of T cell responses in early-stage lung cancer.

Singhal S, Stadanlick J, Annunziata MJ, Rao AS, Bhojnagarwala PS, O'Brien S, Moon EK, Cantu E, Danet-Desnoyers G, Ra HJ, Litzky L, Akimova T, Beier UH, Hancock WW, Albelda SM, Eruslanov EB.

Sci Transl Med. 2019 Feb 13;11(479). pii: eaat1500. doi: 10.1126/scitranslmed.aat1500.

3.

Sirtuin-1 in immunotherapy: A Janus-headed target.

Chadha S, Wang L, Hancock WW, Beier UH.

J Leukoc Biol. 2019 Aug;106(2):337-343. doi: 10.1002/JLB.2RU1118-422R. Epub 2019 Jan 3. Review.

PMID:
30605226
4.

Differential chemokine expression patterns in tonsillar disease.

Mandapathil M, Beier UH, Graefe H, Kröger B, Hedderich J, Maune S, Meyer JE.

Acta Otorhinolaryngol Ital. 2018 Aug;38(4):316-322. doi: 10.14639/0392-100X-1743.

5.

Loss of HDAC6 alters gut microbiota and worsens obesity.

Lieber AD, Beier UH, Xiao H, Wilkins BJ, Jiao J, Li XS, Schugar RC, Strauch CM, Wang Z, Brown JM, Hazen SL, Bokulich NA, Ruggles KV, Akimova T, Hancock WW, Blaser MJ.

FASEB J. 2019 Jan;33(1):1098-1109. doi: 10.1096/fj.201701586R. Epub 2018 Aug 13.

PMID:
30102568
6.

Histone/protein deacetylase inhibitor therapy for enhancement of Foxp3+ T-regulatory cell function posttransplantation.

Wang L, Beier UH, Akimova T, Dahiya S, Han R, Samanta A, Levine MH, Hancock WW.

Am J Transplant. 2018 Jul;18(7):1596-1603. doi: 10.1111/ajt.14749. Epub 2018 Apr 21. Review.

7.

Human neutrophils can mimic myeloid-derived suppressor cells (PMN-MDSC) and suppress microbead or lectin-induced T cell proliferation through artefactual mechanisms.

Negorev D, Beier UH, Zhang T, Quatromoni JG, Bhojnagarwala P, Albelda SM, Singhal S, Eruslanov E, Lohoff FW, Levine MH, Diamond JM, Christie JD, Hancock WW, Akimova T.

Sci Rep. 2018 Feb 16;8(1):3135. doi: 10.1038/s41598-018-21450-6.

8.

Apoptotic Regulatory T Cells Retain Suppressive Function through Adenosine.

Beier UH.

Cell Metab. 2018 Jan 9;27(1):5-7. doi: 10.1016/j.cmet.2017.12.013.

9.

Histone/protein deacetylase 11 targeting promotes Foxp3+ Treg function.

Huang J, Wang L, Dahiya S, Beier UH, Han R, Samanta A, Bergman J, Sotomayor EM, Seto E, Kozikowski AP, Hancock WW.

Sci Rep. 2017 Aug 17;7(1):8626. doi: 10.1038/s41598-017-09211-3.

10.

Human lung tumor FOXP3+ Tregs upregulate four "Treg-locking" transcription factors.

Akimova T, Zhang T, Negorev D, Singhal S, Stadanlick J, Rao A, Annunziata M, Levine MH, Beier UH, Diamond JM, Christie JD, Albelda SM, Eruslanov EB, Hancock WW.

JCI Insight. 2017 Aug 17;2(16). pii: 94075. doi: 10.1172/jci.insight.94075. eCollection 2017 Aug 17.

11.

The Effects of Tacrolimus on T-Cell Proliferation Are Short-Lived: A Pilot Analysis of Immune Function Testing.

Laskin BL, Jiao J, Baluarte HJ, Amaral S, Furth SL, Akimova T, Hancock WW, Levine MH, Reese PP, Beier UH.

Transplant Direct. 2017 Jul 19;3(8):e199. doi: 10.1097/TXD.0000000000000715. eCollection 2017 Aug.

12.

Foxp3 Reprograms T Cell Metabolism to Function in Low-Glucose, High-Lactate Environments.

Angelin A, Gil-de-Gómez L, Dahiya S, Jiao J, Guo L, Levine MH, Wang Z, Quinn WJ 3rd, Kopinski PK, Wang L, Akimova T, Liu Y, Bhatti TR, Han R, Laskin BL, Baur JA, Blair IA, Wallace DC, Hancock WW, Beier UH.

Cell Metab. 2017 Jun 6;25(6):1282-1293.e7. doi: 10.1016/j.cmet.2016.12.018. Epub 2017 Apr 13.

13.

Ubiquitin-specific Protease-7 Inhibition Impairs Tip60-dependent Foxp3+ T-regulatory Cell Function and Promotes Antitumor Immunity.

Wang L, Kumar S, Dahiya S, Wang F, Wu J, Newick K, Han R, Samanta A, Beier UH, Akimova T, Bhatti TR, Nicholson B, Kodrasov MP, Agarwal S, Sterner DE, Gu W, Weinstock J, Butt TR, Albelda SM, Hancock WW.

EBioMedicine. 2016 Nov;13:99-112. doi: 10.1016/j.ebiom.2016.10.018. Epub 2016 Oct 15.

14.

Proximity Ligation Assay to Quantify Foxp3 Acetylation in Regulatory T Cells.

Jiao J, Han R, Hancock WW, Beier UH.

Methods Mol Biol. 2017;1510:287-293.

15.

Targeting Sirtuin-1 prolongs murine renal allograft survival and function.

Levine MH, Wang Z, Xiao H, Jiao J, Wang L, Bhatti TR, Hancock WW, Beier UH.

Kidney Int. 2016 May;89(5):1016-1026. doi: 10.1016/j.kint.2015.12.051. Epub 2016 Mar 16.

16.

The Noninvasive Urinary Polyomavirus Haufen Test Predicts BK Virus Nephropathy in Children After Hematopoietic Cell Transplantation: A Pilot Study.

Laskin BL, Singh HK, Beier UH, Moatz T, Furth SL, Bunin N, Witte D, Goebel J, Davies SM, Dandoy C, Jodele S, Nickeleit V.

Transplantation. 2016 Oct;100(10):e81-7. doi: 10.1097/TP.0000000000001085.

17.

HDAC5 controls the functions of Foxp3(+) T-regulatory and CD8(+) T cells.

Xiao H, Jiao J, Wang L, O'Brien S, Newick K, Wang LC, Falkensammer E, Liu Y, Han R, Kapoor V, Hansen FK, Kurz T, Hancock WW, Beier UH.

Int J Cancer. 2016 May 15;138(10):2477-86. doi: 10.1002/ijc.29979. Epub 2016 Jan 19.

18.

Standardization, Evaluation, and Area-Under-Curve Analysis of Human and Murine Treg Suppressive Function.

Akimova T, Levine MH, Beier UH, Hancock WW.

Methods Mol Biol. 2016;1371:43-78. doi: 10.1007/978-1-4939-3139-2_4.

19.

FOXP3⁺ regulatory T cell development and function require histone/protein deacetylase 3.

Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW.

J Clin Invest. 2015 Aug 3;125(8):3304. doi: 10.1172/JCI83084. Epub 2015 Aug 3. No abstract available.

20.

Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival.

Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW.

FASEB J. 2015 Jun;29(6):2315-26. doi: 10.1096/fj.14-268409. Epub 2015 Feb 13.

21.

FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.

Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW.

J Clin Invest. 2015 Mar 2;125(3):1111-23. doi: 10.1172/JCI77088. Epub 2015 Feb 2. Erratum in: J Clin Invest. 2015 Aug 3;125(8):3304.

22.

Two histone/protein acetyltransferases, CBP and p300, are indispensable for Foxp3+ T-regulatory cell development and function.

Liu Y, Wang L, Han R, Beier UH, Akimova T, Bhatti T, Xiao H, Cole PA, Brindle PK, Hancock WW.

Mol Cell Biol. 2014 Nov;34(21):3993-4007. doi: 10.1128/MCB.00919-14. Epub 2014 Aug 25.

23.

Targeting sirtuin-1 alleviates experimental autoimmune colitis by induction of Foxp3+ T-regulatory cells.

Akimova T, Xiao H, Liu Y, Bhatti TR, Jiao J, Eruslanov E, Singhal S, Wang L, Han R, Zacharia K, Hancock WW, Beier UH.

Mucosal Immunol. 2014 Sep;7(5):1209-20. doi: 10.1038/mi.2014.10. Epub 2014 Feb 19.

24.

Mbd2 promotes foxp3 demethylation and T-regulatory-cell function.

Wang L, Liu Y, Han R, Beier UH, Thomas RM, Wells AD, Hancock WW.

Mol Cell Biol. 2013 Oct;33(20):4106-15. doi: 10.1128/MCB.00144-13. Epub 2013 Aug 26.

25.

Inhibition of p300 impairs Foxp3⁺ T regulatory cell function and promotes antitumor immunity.

Liu Y, Wang L, Predina J, Han R, Beier UH, Wang LC, Kapoor V, Bhatti TR, Akimova T, Singhal S, Brindle PK, Cole PA, Albelda SM, Hancock WW.

Nat Med. 2013 Sep;19(9):1173-7. doi: 10.1038/nm.3286. Epub 2013 Aug 18.

26.

Foxp3+ T-regulatory cells require DNA methyltransferase 1 expression to prevent development of lethal autoimmunity.

Wang L, Liu Y, Beier UH, Han R, Bhatti TR, Akimova T, Hancock WW.

Blood. 2013 May 2;121(18):3631-9. doi: 10.1182/blood-2012-08-451765. Epub 2013 Feb 26.

27.

Combination of isoform-selective histone/protein deacetylase inhibitors improves Foxp3+ T-regulatory cell function.

Beier UH, Wang L, Hancock WW.

Cell Cycle. 2012 Sep 15;11(18):3351-2. doi: 10.4161/cc.21876. Epub 2012 Aug 23.

28.

Histone deacetylases 6 and 9 and sirtuin-1 control Foxp3+ regulatory T cell function through shared and isoform-specific mechanisms.

Beier UH, Wang L, Han R, Akimova T, Liu Y, Hancock WW.

Sci Signal. 2012 Jun 19;5(229):ra45. doi: 10.1126/scisignal.2002873.

29.

HDAC inhibitor therapy in autoimmunity and transplantation.

Hancock WW, Akimova T, Beier UH, Liu Y, Wang L.

Ann Rheum Dis. 2012 Apr;71 Suppl 2:i46-54. doi: 10.1136/annrheumdis-2011-200593. Review.

PMID:
22460138
30.

Two lysines in the forkhead domain of foxp3 are key to T regulatory cell function.

Liu Y, Wang L, Han R, Beier UH, Hancock WW.

PLoS One. 2012;7(1):e29035. doi: 10.1371/journal.pone.0029035. Epub 2012 Jan 11.

31.

Histone/protein deacetylases and T-cell immune responses.

Akimova T, Beier UH, Liu Y, Wang L, Hancock WW.

Blood. 2012 Mar 15;119(11):2443-51. doi: 10.1182/blood-2011-10-292003. Epub 2012 Jan 12. Review.

32.

Helios expression is a marker of T cell activation and proliferation.

Akimova T, Beier UH, Wang L, Levine MH, Hancock WW.

PLoS One. 2011;6(8):e24226. doi: 10.1371/journal.pone.0024226. Epub 2011 Aug 30.

33.

Histone/protein deacetylases control Foxp3 expression and the heat shock response of T-regulatory cells.

Beier UH, Akimova T, Liu Y, Wang L, Hancock WW.

Curr Opin Immunol. 2011 Oct;23(5):670-8. doi: 10.1016/j.coi.2011.07.002. Epub 2011 Jul 26. Review.

34.

Histone deacetylase 6 and heat shock protein 90 control the functions of Foxp3(+) T-regulatory cells.

de Zoeten EF, Wang L, Butler K, Beier UH, Akimova T, Sai H, Bradner JE, Mazitschek R, Kozikowski AP, Matthias P, Hancock WW.

Mol Cell Biol. 2011 May;31(10):2066-78. doi: 10.1128/MCB.05155-11. Epub 2011 Mar 28.

35.

Sirtuin-1 targeting promotes Foxp3+ T-regulatory cell function and prolongs allograft survival.

Beier UH, Wang L, Bhatti TR, Liu Y, Han R, Ge G, Hancock WW.

Mol Cell Biol. 2011 Mar;31(5):1022-9. doi: 10.1128/MCB.01206-10. Epub 2011 Jan 3.

36.

Control of disseminated intravascular coagulation in Klippel-Trenaunay-Weber syndrome using enoxaparin and recombinant activated factor VIIa: a case report.

Beier UH, Schmidt ML, Hast H, Kecskes S, Valentino LA.

J Med Case Rep. 2010 Mar 19;4:92. doi: 10.1186/1752-1947-4-92.

37.

Gene alterations in head and neck carcinomas and their role in promoting malignant behavior (Review).

Görögh T, Beier UH.

Int J Oncol. 2010 Mar;36(3):525-32. Review.

PMID:
20126971
38.

Caring for adolescent renal patients.

Beier UH, Green C, Meyers KE.

Kidney Int. 2010 Feb;77(4):285-91. doi: 10.1038/ki.2009.462. Epub 2009 Dec 9. Review.

39.

The effect of tezosentan after cold ischemia and renal artery clamping as a model of reperfusion injury in newborn piglets.

Pham J, Beier UH, Fornell L, Chin A, Samuel S, Radhakrishnan J, John E.

Transplant Proc. 2008 Jun;40(5):1294-9. doi: 10.1016/j.transproceed.2008.02.071.

PMID:
18589090
40.

C-reactive protein is a poor predictor of bacterial pneumonia.

Gutierrez M, Beier UH, Hupert J, Niederman LG, Schwartz A.

Pediatr Infect Dis J. 2008 Jul;27(7):670; author reply 670-1. doi: 10.1097/INF.0b013e318174e0d7. No abstract available.

PMID:
18520442
41.

The effect of indomethacin on systemic and renal hemodynamics in neonatal piglets during experimental endotoxemia.

Furtado N, Beier UH, Gorla SR, Fornell L, Lumpaopong A, Radhakrishnan J, John E.

Pediatr Surg Int. 2008 Aug;24(8):907-11. doi: 10.1007/s00383-008-2175-z. Epub 2008 May 29.

PMID:
18509659
42.

Electrolyte imbalances in pediatric living related small bowel transplantation.

Beier UH, Kaplan B, Setty S, Samuel S, Mathew AV, Oberholzer J, Benedetti E, John E.

Transplantation. 2008 Jan 27;85(2):217-23. doi: 10.1097/TP.0b013e31816025b4.

PMID:
18212626
43.

Early effects of lipopolysaccharide on cytokine release, hemodynamic and renal function in newborn piglets.

John E, Pais P, Furtado N, Chin A, Radhakrishnan J, Fornell L, Lumpaopong A, Beier UH.

Neonatology. 2008;93(2):106-12. Epub 2007 Aug 16.

PMID:
17703105
44.

Financial incentives to promote prolonged renal graft survival: potential for patients and public health.

Beier UH, Hidalgo G, John E.

Med Hypotheses. 2008;70(2):218-20. Epub 2007 Aug 1.

PMID:
17683877
45.

Overexpression of Pim-1 in head and neck squamous cell carcinomas.

Beier UH, Weise JB, Laudien M, Sauerwein H, Görögh T.

Int J Oncol. 2007 Jun;30(6):1381-7.

PMID:
17487358
46.

Fibronectin suppression in head and neck cancers, inflammatory tissues and the molecular mechanisms potentially involved.

Beier UH, Holtmeier C, Weise JB, Görögh T.

Int J Oncol. 2007 Mar;30(3):621-9.

PMID:
17273763
47.

Cardiac computed tomography compared to transthoracic echocardiography in the management of congenital heart disease.

Beier UH, Jelnin V, Jain S, Ruiz CE.

Catheter Cardiovasc Interv. 2006 Sep;68(3):441-9.

PMID:
16897779
48.

Overexpression of p68 mRNA in head and neck squamous cell carcinoma cells.

Beier UH, Maune S, Meyer JE, Görögh T.

Anticancer Res. 2006 May-Jun;26(3A):1941-6.

49.

Nasal RANTES and eotaxin production pattern in response to rhinovirus infection.

Meyer JE, Stangenberg S, Weise JB, Beck C, Schmidt C, Kurz K, Beier UH, Maune S.

Rhinology. 2006 Jun;44(2):140-4.

PMID:
16792174
50.

Electron-beam CT as a diagnostic modality in pediatric nephrology and renal transplant surgery.

Beier UH, John E, Lumpaopong A, Co JG, Jelnin V, Benedetti E, Testa G, Bottke R, Sharon BI, Ruiz CE.

Pediatr Nephrol. 2006 May;21(5):677-82. Epub 2006 Mar 7.

PMID:
16520947

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