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Items: 44


Temporal changes in Plasmodium falciparum reticulocyte binding protein homolog 2b (PfRh2b) in Senegal and The Gambia.

Diédhiou CK, Moussa RA, Bei AK, Daniels R, Papa Mze N, Ndiaye D, Faye N, Wirth D, Amambua-Ngwa A, Mboup S, Ahouidi AD.

Malar J. 2019 Jul 16;18(1):239. doi: 10.1186/s12936-019-2868-x.


De Novo Mutations Resolve Disease Transmission Pathways in Clonal Malaria.

Redmond SN, MacInnis BM, Bopp S, Bei AK, Ndiaye D, Hartl DL, Wirth DF, Volkman SK, Neafsey DE.

Mol Biol Evol. 2018 Jul 1;35(7):1678-1689. doi: 10.1093/molbev/msy059.


Dramatic Changes in Malaria Population Genetic Complexity in Dielmo and Ndiop, Senegal, Revealed Using Genomic Surveillance.

Bei AK, Niang M, Deme AB, Daniels RF, Sarr FD, Sokhna C, Talla C, Faye J, Diagne N, Doucoure S, Mboup S, Wirth DF, Tall A, Ndiaye D, Hartl DL, Volkman SK, Toure-Balde A.

J Infect Dis. 2018 Jan 30;217(4):622-627. doi: 10.1093/infdis/jix580.


Factors influencing the use of malaria prevention strategies by women in Senegal: a cross-sectional study.

Mbengue MAS, Bei AK, Mboup A, Ahouidi A, Sarr M, Mboup S, Gaye O.

Malar J. 2017 Nov 21;16(1):470. doi: 10.1186/s12936-017-2095-2.


Genetic Evidence for Erythrocyte Receptor Glycophorin B Expression Levels Defining a Dominant Plasmodium falciparum Invasion Pathway into Human Erythrocytes.

Dankwa S, Chaand M, Kanjee U, Jiang RHY, Nobre LV, Goldberg JM, Bei AK, Moechtar MA, Grüring C, Ahouidi AD, Ndiaye D, Dieye TN, Mboup S, Weekes MP, Duraisingh MT.

Infect Immun. 2017 Sep 20;85(10). pii: e00074-17. doi: 10.1128/IAI.00074-17. Print 2017 Oct.


Ex vivo susceptibility and genotyping of Plasmodium falciparum isolates from Pikine, Senegal.

Mbaye A, Gaye A, Dieye B, Ndiaye YD, Bei AK, Affara M, Deme AB, Yade MS, Diongue K, Ndiaye IM, Ndiaye T, Sy M, Sy N, Koita O, Krogstad DJ, Volkman S, Nwakanma D, Ndiaye D.

Malar J. 2017 Jun 14;16(1):250. doi: 10.1186/s12936-017-1897-6.


Functional Analysis Reveals Geographical Variation in Inhibitory Immune Responses Against a Polymorphic Malaria Antigen.

Bei AK, Ahouidi AD, Dvorin JD, Miura K, Diouf A, Ndiaye D, Premji Z, Diakite M, Mboup S, Long CA, Duraisingh MT.

J Infect Dis. 2017 Jul 15;216(2):267-275. doi: 10.1093/infdis/jix280.


High resolution melting: a useful field-deployable method to measure dhfr and dhps drug resistance in both highly and lowly endemic Plasmodium populations.

Ndiaye YD, Diédhiou CK, Bei AK, Dieye B, Mbaye A, Mze NP, Daniels RF, Ndiaye IM, Déme AB, Gaye A, Sy M, Ndiaye T, Badiane AS, Ndiaye M, Premji Z, Wirth DF, Mboup S, Krogstad D, Volkman SK, Ahouidi AD, Ndiaye D.

Malar J. 2017 Apr 19;16(1):153. doi: 10.1186/s12936-017-1811-2.


Continued Transmission of Zika Virus in Humans in West Africa, 1992-2016.

Herrera BB, Chang CA, Hamel DJ, Mboup S, Ndiaye D, Imade G, Okpokwu J, Agbaji O, Bei AK, Kanki PJ.

J Infect Dis. 2017 May 15;215(10):1546-1550. doi: 10.1093/infdis/jix182.


Genetic relatedness analysis reveals the cotransmission of genetically related Plasmodium falciparum parasites in Thiès, Senegal.

Wong W, Griggs AD, Daniels RF, Schaffner SF, Ndiaye D, Bei AK, Deme AB, MacInnis B, Volkman SK, Hartl DL, Neafsey DE, Wirth DF.

Genome Med. 2017 Jan 24;9(1):5. doi: 10.1186/s13073-017-0398-0.


Selection of N86F184D1246 haplotype of Pfmrd1 gene by artemether-lumefantrine drug pressure on Plasmodium falciparum populations in Senegal.

Mbaye A, Dieye B, Ndiaye YD, Bei AK, Muna A, Deme AB, Yade MS, Diongue K, Gaye A, Ndiaye IM, Ndiaye T, Sy M, Diallo MA, Badiane AS, Ndiaye M, Seck MC, Sy N, Koita O, Krogstad DJ, Nwakanma D, Ndiaye D.

Malar J. 2016 Aug 25;15(1):433. doi: 10.1186/s12936-016-1490-4.


[Use of dried blood spots in early diagnosis of HIV-1 infection in children born to HIV-infected mothers as part of the prevention of mother-to-child transmission in Benin].

Tchiakpe E, Hounto-Ogouyemi A, Diop Ndiaye H, Diouara AA, Aïssi AK, Keke RK, Kpangon AA, Lafia B, Métadokou D, Bouraïma B, Anthony D, Hounsinou A, Alao MJ, Azondekon A, Ahouidi AD, Bei AK, Mbengue MA, Touré Kane C, Zannou DM.

Bull Soc Pathol Exot. 2016 Aug;109(3):155-9. doi: 10.1007/s13149-016-0509-y. Epub 2016 Jul 7. French.


Ancient human sialic acid variant restricts an emerging zoonotic malaria parasite.

Dankwa S, Lim C, Bei AK, Jiang RH, Abshire JR, Patel SD, Goldberg JM, Moreno Y, Kono M, Niles JC, Duraisingh MT.

Nat Commun. 2016 Apr 4;7:11187. doi: 10.1038/ncomms11187.


Malaria Vaccine Development: Focusing Field Erythrocyte Invasion Studies on Phenotypic Diversity: The West African Merozoite Invasion Network (WAMIN).

WAMIN consortium authors include (in alphabetical order):, Ahouidi AD, Amambua-Ngwa A, Awandare GA, Bei AK, Conway DJ, Diakite M, Duraisingh MT, Rayner JC, Zenonos ZA.

Trends Parasitol. 2016 Apr;32(4):274-283. doi: 10.1016/ Epub 2015 Dec 23. Review.


The Clinically Tested Gardos Channel Inhibitor Senicapoc Exhibits Antimalarial Activity.

Tubman VN, Mejia P, Shmukler BE, Bei AK, Alper SL, Mitchell JR, Brugnara C, Duraisingh MT.

Antimicrob Agents Chemother. 2015 Oct 12;60(1):613-6. doi: 10.1128/AAC.01668-15. Print 2016 Jan.


Measuring Plasmodium falciparum Erythrocyte Invasion Phenotypes Using Flow Cytometry.

Bei AK, Duraisingh MT.

Methods Mol Biol. 2015;1325:167-86. doi: 10.1007/978-1-4939-2815-6_14.


RDTs as a source of DNA to study Plasmodium falciparum drug resistance in isolates from Senegal and the Comoros Islands.

Papa Mze N, Ndiaye YD, Diedhiou CK, Rahamatou S, Dieye B, Daniels RF, Hamilton EJ, Diallo M, Bei AK, Wirth DF, Mboup S, Volkman SK, Ahouidi AD, Ndiaye D.

Malar J. 2015 Sep 29;14:373. doi: 10.1186/s12936-015-0861-6.


Immune characterization of Plasmodium falciparum parasites with a shared genetic signature in a region of decreasing transmission.

Bei AK, Diouf A, Miura K, Larremore DB, Ribacke U, Tullo G, Moss EL, Neafsey DE, Daniels RF, Zeituni AE, Nosamiefan I, Volkman SK, Ahouidi AD, Ndiaye D, Dieye T, Mboup S, Buckee CO, Long CA, Wirth DF.

Infect Immun. 2015 Jan;83(1):276-85. doi: 10.1128/IAI.01979-14. Epub 2014 Nov 3.


STEVOR is a Plasmodium falciparum erythrocyte binding protein that mediates merozoite invasion and rosetting.

Niang M, Bei AK, Madnani KG, Pelly S, Dankwa S, Kanjee U, Gunalan K, Amaladoss A, Yeo KP, Bob NS, Malleret B, Duraisingh MT, Preiser PR.

Cell Host Microbe. 2014 Jul 9;16(1):81-93. doi: 10.1016/j.chom.2014.06.004.


An adjustable gas-mixing device to increase feasibility of in vitro culture of Plasmodium falciparum parasites in the field.

Bei AK, Patel SD, Volkman SK, Ahouidi AD, Ndiaye D, Mboup S, Wirth DF.

PLoS One. 2014 Mar 6;9(3):e90928. doi: 10.1371/journal.pone.0090928. eCollection 2014.


Polymorphism in dhfr/dhps genes, parasite density and ex vivo response to pyrimethamine in Plasmodium falciparum malaria parasites in Thies, Senegal.

Ndiaye D, Dieye B, Ndiaye YD, Van Tyne D, Daniels R, Bei AK, Mbaye A, Valim C, Lukens A, Mboup S, Ndir O, Wirth DF, Volkman S.

Int J Parasitol Drugs Drug Resist. 2013 Aug 12;3:135-42. doi: 10.1016/j.ijpddr.2013.07.001. eCollection 2013 Dec.


Analysis of pfhrp2 genetic diversity in Senegal and implications for use of rapid diagnostic tests.

Deme AB, Park DJ, Bei AK, Sarr O, Badiane AS, Gueye Pel H, Ahouidi A, Ndir O, Mboup S, Wirth DF, Ndiaye D, Volkman SK.

Malar J. 2014 Jan 29;13:34. doi: 10.1186/1475-2875-13-34.


Changes in drug sensitivity and anti-malarial drug resistance mutations over time among Plasmodium falciparum parasites in Senegal.

Van Tyne D, Dieye B, Valim C, Daniels RF, Sène PD, Lukens AK, Ndiaye M, Bei AK, Ndiaye YD, Hamilton EJ, Ndir O, Mboup S, Volkman SK, Wirth DF, Ndiaye D.

Malar J. 2013 Dec 6;12:441. doi: 10.1186/1475-2875-12-441.


Plasmodium falciparum merozoite surface antigen, PfRH5, elicits detectable levels of invasion-inhibiting antibodies in humans.

Patel SD, Ahouidi AD, Bei AK, Dieye TN, Mboup S, Harrison SC, Duraisingh MT.

J Infect Dis. 2013 Nov 15;208(10):1679-87. doi: 10.1093/infdis/jit385. Epub 2013 Jul 31.


Inhibitory humoral responses to the Plasmodium falciparum vaccine candidate EBA-175 are independent of the erythrocyte invasion pathway.

Badiane AS, Bei AK, Ahouidi AD, Patel SD, Salinas N, Ndiaye D, Sarr O, Ndir O, Tolia NH, Mboup S, Duraisingh MT.

Clin Vaccine Immunol. 2013 Aug;20(8):1238-45. doi: 10.1128/CVI.00135-13. Epub 2013 Jun 12.


Nuclear repositioning precedes promoter accessibility and is linked to the switching frequency of a Plasmodium falciparum invasion gene.

Coleman BI, Ribacke U, Manary M, Bei AK, Winzeler EA, Wirth DF, Duraisingh MT.

Cell Host Microbe. 2012 Dec 13;12(6):739-50. doi: 10.1016/j.chom.2012.11.004.


Distribution of erythrocyte binding antigen 175 (EBA-175) alleles and ABO blood groups in a hypoendemic area in Senegal.

Badiane AS, Sarr O, Deme AB, Ahouidi AD, Gueye PE, Ndiaye M, Seck MC, Diallo M, Bei AK, Duraisingh MT, Wirth D, Ndiaye D, Ndir O, Mboup S.

J Infect Dev Ctries. 2012 Oct 19;6(10):727-33. doi: 10.3855/jidc.2587.


Functional analysis of erythrocyte determinants of Plasmodium infection.

Bei AK, Duraisingh MT.

Int J Parasitol. 2012 May 15;42(6):575-82. doi: 10.1016/j.ijpara.2012.03.006. Epub 2012 Apr 19. Review.


Evolution of the pfcrt T76 and pfmdr1 Y86 markers and chloroquine susceptibility 8 years after cessation of chloroquine use in Pikine, Senegal.

Ly O, Gueye PE, Deme AB, Dieng T, Badiane AS, Ahouidi AD, Diallo M, Bei AK, Wirth DF, Mboup S, Sarr O.

Parasitol Res. 2012 Oct;111(4):1541-6. Epub 2012 Jun 17.


SNP genotyping identifies new signatures of selection in a deep sample of West African Plasmodium falciparum malaria parasites.

Amambua-Ngwa A, Park DJ, Volkman SK, Barnes KG, Bei AK, Lukens AK, Sene P, Van Tyne D, Ndiaye D, Wirth DF, Conway DJ, Neafsey DE, Schaffner SF.

Mol Biol Evol. 2012 Nov;29(11):3249-53. doi: 10.1093/molbev/mss151. Epub 2012 Jun 11.


Improving malaria control in West Africa: interruption of transmission as a paradigm shift.

Doumbia SO, Ndiaye D, Koita OA, Diakité M, Nwakanma D, Coulibaly M, Traoré SF, Keating J, Milner DA Jr, Ndiaye JL, Sene PD, Ahouidi A, Dieye TN, Gaye O, Okebe J, Ceesay SJ, Ngwa A, Oriero EC, Konaté L, Sy N, Jawara M, Faye O, Kéita M, Cissé M, Sogoba N, Poudiougou B, Diawara S, Sangaré L, Coulibaly T, Seck I, Abubakar I, Gomis J, Mather FJ, Sissako A, Diarra A, Kandeh B, Whalen C, Moyer B, Nnedu O, Thiero O, Bei AK, Daniels R, Miura K, Long CA, Fairhurst RM, Duraisingh M, Muskavitch MA, D'Alessandro U, Conway DJ, Volkman SK, Valim C, Wirth DF, Krogstad DJ.

Acta Trop. 2012 Mar;121(3):175-83. doi: 10.1016/j.actatropica.2011.11.009. Epub 2011 Nov 28.


Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.

Crosnier C, Bustamante LY, Bartholdson SJ, Bei AK, Theron M, Uchikawa M, Mboup S, Ndir O, Kwiatkowski DP, Duraisingh MT, Rayner JC, Wright GJ.

Nature. 2011 Nov 9;480(7378):534-7. doi: 10.1038/nature10606.


Functional analysis of epigenetic regulation of tandem RhopH1/clag genes reveals a role in Plasmodium falciparum growth.

Comeaux CA, Coleman BI, Bei AK, Whitehurst N, Duraisingh MT.

Mol Microbiol. 2011 Apr;80(2):378-90. doi: 10.1111/j.1365-2958.2011.07572.x. Epub 2011 Mar 7.


In vitro genetic analysis of an erythrocyte determinant of malaria infection.

Bei AK, Brugnara C, Duraisingh MT.

J Infect Dis. 2010 Dec 1;202(11):1722-7. doi: 10.1086/657157. Epub 2010 Oct 19.


Functional diversification between two related Plasmodium falciparum merozoite invasion ligands is determined by changes in the cytoplasmic domain.

Dvorin JD, Bei AK, Coleman BI, Duraisingh MT.

Mol Microbiol. 2010 Feb;75(4):990-1006. doi: 10.1111/j.1365-2958.2009.07040.x.


A flow cytometry-based assay for measuring invasion of red blood cells by Plasmodium falciparum.

Bei AK, Desimone TM, Badiane AS, Ahouidi AD, Dieye T, Ndiaye D, Sarr O, Ndir O, Mboup S, Duraisingh MT.

Am J Hematol. 2010 Apr;85(4):234-7. doi: 10.1002/ajh.21642.


Population genetic analysis of large sequence polymorphisms in Plasmodium falciparum blood-stage antigens.

Ahouidi AD, Bei AK, Neafsey DE, Sarr O, Volkman S, Milner D, Cox-Singh J, Ferreira MU, Ndir O, Premji Z, Mboup S, Duraisingh MT.

Infect Genet Evol. 2010 Mar;10(2):200-6. doi: 10.1016/j.meegid.2009.11.008. Epub 2009 Nov 30.


Cooperativity between Plasmodium falciparum adhesive proteins for invasion into erythrocytes.

DeSimone TM, Jennings CV, Bei AK, Comeaux C, Coleman BI, Refour P, Triglia T, Stubbs J, Cowman AF, Duraisingh MT.

Mol Microbiol. 2009 May;72(3):578-89. doi: 10.1111/j.1365-2958.2009.06667.x.


Trypanosoma cruzi triggers an early type I IFN response in vivo at the site of intradermal infection.

Chessler AD, Unnikrishnan M, Bei AK, Daily JP, Burleigh BA.

J Immunol. 2009 Feb 15;182(4):2288-96. doi: 10.4049/jimmunol.0800621.


Erythrocyte invasion profiles are associated with a common invasion ligand polymorphism in Senegalese isolates of Plasmodium falciparum.

Lantos PM, Ahouidi AD, Bei AK, Jennings CV, Sarr O, Ndir O, Wirth DF, Mboup S, Duraisingh MT.

Parasitology. 2009 Jan;136(1):1-9. doi: 10.1017/S0031182008005167.


Genetic analysis of the cytoplasmic domain of the PfRh2b merozoite invasion protein of Plasmodium falciparum.

DeSimone TM, Bei AK, Jennings CV, Duraisingh MT.

Int J Parasitol. 2009 Mar;39(4):399-405. doi: 10.1016/j.ijpara.2008.08.008. Epub 2008 Sep 19.


Molecular analysis of erythrocyte invasion in Plasmodium falciparum isolates from Senegal.

Jennings CV, Ahouidi AD, Zilversmit M, Bei AK, Rayner J, Sarr O, Ndir O, Wirth DF, Mboup S, Duraisingh MT.

Infect Immun. 2007 Jul;75(7):3531-8. Epub 2007 Apr 30.


Variant merozoite protein expression is associated with erythrocyte invasion phenotypes in Plasmodium falciparum isolates from Tanzania.

Bei AK, Membi CD, Rayner JC, Mubi M, Ngasala B, Sultan AA, Premji Z, Duraisingh MT.

Mol Biochem Parasitol. 2007 May;153(1):66-71. Epub 2007 Jan 16. No abstract available. Erratum in: Mol Biochem Parasitol. 2007 Aug;154(2):195.


A mitogen-activated protein kinase regulates male gametogenesis and transmission of the malaria parasite Plasmodium berghei.

Rangarajan R, Bei AK, Jethwaney D, Maldonado P, Dorin D, Sultan AA, Doerig C.

EMBO Rep. 2005 May;6(5):464-9.

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