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TAFI deficiency causes maladaptive vascular remodeling after hemophilic joint bleeding.

Wyseure T, Yang T, Zhou JY, Cooke EJ, Wanko B, Olmer M, Agashe R, Morodomi Y, Behrendt N, Lotz M, Morser J, von Drygalski A, Mosnier LO.

JCI Insight. 2019 Oct 3;4(19). pii: 128379. doi: 10.1172/jci.insight.128379.


Examination of Prenatal Sonographic Findings: Intra-Abdominal Bowel Dilation Predicts Poor Gastroschisis Outcomes.

Dewberry LC, Hilton SA, Zaretsky MV, Behrendt N, Galan HL, Marwan AI, Liechty KW.

Fetal Diagn Ther. 2019 Aug 27:1-6. doi: 10.1159/000501592. [Epub ahead of print]


MOMS Plus: Single-Institution Review of Outcomes for Extended BMI Criteria for Open Fetal Repair of Myelomeningocele.

Hilton SA, Hodges MM, Dewberry LC, Handler M, Galan HL, Zaretsky MV, Behrendt N, Marwan AI, Liechty KW.

Fetal Diagn Ther. 2019 May 2:1-4. doi: 10.1159/000499484. [Epub ahead of print]


Pediatric toxic epidermal necrolysis treated successfully with infliximab.

Chafranska L, Saunte DM, Behrendt N, Nygaard U, Christensen RJ, Sand C, Jemec GB.

Pediatr Dermatol. 2019 May;36(3):342-345. doi: 10.1111/pde.13778. Epub 2019 Mar 4.


uPARAP/Endo180 receptor is a gatekeeper of VEGFR-2/VEGFR-3 heterodimerisation during pathological lymphangiogenesis.

Durré T, Morfoisse F, Erpicum C, Ebroin M, Blacher S, García-Caballero M, Deroanne C, Louis T, Balsat C, Van de Velde M, Kaijalainen S, Kridelka F, Engelholm L, Struman I, Alitalo K, Behrendt N, Paupert J, Noel A.

Nat Commun. 2018 Dec 5;9(1):5178. doi: 10.1038/s41467-018-07514-1.


Immune regulation by fibroblasts in tissue injury depends on uPARAP-mediated uptake of collectins.

Jürgensen HJ, Nørregaard KS, Sibree MM, Santoni-Rugiu E, Madsen DH, Wassilew K, Krustrup D, Garred P, Bugge TH, Engelholm LH, Behrendt N.

J Cell Biol. 2019 Jan 7;218(1):333-349. doi: 10.1083/jcb.201802148. Epub 2018 Oct 26.


Primary and secondary mucosal melanoma of the small intestine - a clinical, pathological, and genetic nationwide survey of Danish patients between 1980 and 2014.

Tingsgaard JK, Henriksen A, Mikkelsen LH, Behrendt N, Melchior LC, Svendsen LB, Heegaard S.

APMIS. 2018 Sep;126(9):739-745. doi: 10.1111/apm.12883.


Indomethacin Dosing and Constriction of the Ductus Arteriosus During Open Fetal Surgery for Myelomeningocele Repair.

Howley LW, Chatterjee D, Patel SS, Cuneo BF, Crombleholme TM, Behrendt N, Zaretsky MV, Marwan AI, Zuk J, Galan HL, Wood C.

Fetal Diagn Ther. 2019;45(5):339-344. doi: 10.1159/000491748. Epub 2018 Aug 29.


Defective TAFI activation in hemophilia A mice is a major contributor to joint bleeding.

Wyseure T, Cooke EJ, Declerck PJ, Behrendt N, Meijers JCM, von Drygalski A, Mosnier LO.

Blood. 2018 Oct 11;132(15):1593-1603. doi: 10.1182/blood-2018-01-828434. Epub 2018 Jul 19.


Tumor-Associated Macrophages Derived from Circulating Inflammatory Monocytes Degrade Collagen through Cellular Uptake.

Madsen DH, Jürgensen HJ, Siersbæk MS, Kuczek DE, Grey Cloud L, Liu S, Behrendt N, Grøntved L, Weigert R, Bugge TH.

Cell Rep. 2017 Dec 26;21(13):3662-3671. doi: 10.1016/j.celrep.2017.12.011.


The importance of hCG in human endometrial adenocarcinoma and breast cancer.

Kölbl AC, Schlenk K, Behrendt N, Andergassen U.

Int J Biol Markers. 2018 Jan;33(1):33-39. doi: 10.5301/ijbm.5000290. Review.


HLA class Ia and Ib molecules and FOXP3+ TILs in relation to the prognosis of malignant melanoma patients.

Melsted WN, Johansen LL, Lock-Andersen J, Behrendt N, Eriksen JO, Bzorek M, Scheike T, Hviid TVF.

Clin Immunol. 2017 Oct;183:191-197. doi: 10.1016/j.clim.2017.09.004. Epub 2017 Sep 4.


Modified Hysterotomy Closure Technique for Open Fetal Surgery.

Zaretsky MV, Liechty KW, Galan HL, Behrendt NJ, Reeves S, Marwan AI, Wilkinson C, Handler M, Lagueux M, Crombleholme TM.

Fetal Diagn Ther. 2018;44(2):105-111. doi: 10.1159/000479683. Epub 2017 Sep 6.


[Expression of cancer testis (CT) antigens in pediatric and adolescent melanomas].

Behrendt N, Schultewolter T, Busam K, Frosina D, Spagnoli G, Jungbluth A.

Pathologe. 2017 Jul;38(4):303-311. doi: 10.1007/s00292-017-0311-z. Review. German.


Case report of myometrial window following fetoscopic treatment of twin-twin transfusion syndrome: indications of underlying collagen vascular disease?

Zaretsky MV, Manchester DK, Galan HL, Behrendt NJ, Marwan AI, Liechty KW, Crombleholme TM.

Clin Case Rep. 2017 May 9;5(6):975-979. doi: 10.1002/ccr3.885. eCollection 2017 Jun.


The collagen receptor uPARAP/Endo180 as a novel target for antibody-drug conjugate mediated treatment of mesenchymal and leukemic cancers.

Nielsen CF, van Putten SM, Lund IK, Melander MC, Nørregaard KS, Jürgensen HJ, Reckzeh K, Christensen KR, Ingvarsen SZ, Gårdsvoll H, Jensen KE, Hamerlik P, Engelholm LH, Behrendt N.

Oncotarget. 2017 Jul 4;8(27):44605-44624. doi: 10.18632/oncotarget.17883.


Myosin-1E interacts with FAK proline-rich region 1 to induce fibronectin-type matrix.

Heim JB, Squirewell EJ, Neu A, Zocher G, Sominidi-Damodaran S, Wyles SP, Nikolova E, Behrendt N, Saunte DM, Lock-Andersen J, Gaonkar KS, Yan H, Sarkaria JN, Krendel M, van Deursen J, Sprangers R, Stehle T, Böttcher RT, Lee JH, Ordog T, Meves A.

Proc Natl Acad Sci U S A. 2017 Apr 11;114(15):3933-3938. doi: 10.1073/pnas.1614894114. Epub 2017 Mar 27.


Phagocytosis of Collagen Fibrils by Fibroblasts In Vivo Is Independent of the uPARAP/Endo180 Receptor.

Sprangers S, Behrendt N, Engelholm L, Cao Y, Everts V.

J Cell Biochem. 2017 Jun;118(6):1590-1595. doi: 10.1002/jcb.25821. Epub 2017 Jan 11.


Endoscopic Ultrasound-Guided Liver Biopsy in the Hands of a Chest Physician.

Fally M, Nessar R, Behrendt N, Clementsen PF.

Respiration. 2016;92(1):53-5. doi: 10.1159/000446924. Epub 2016 Jun 8.


Crystal structures of the ligand-binding region of uPARAP: effect of calcium ion binding.

Yuan C, Jürgensen HJ, Engelholm LH, Li R, Liu M, Jiang L, Luo Z, Behrendt N, Huang M.

Biochem J. 2016 Aug 1;473(15):2359-68. doi: 10.1042/BCJ20160276. Epub 2016 May 31.


Ultrasound versus MRI: is there a difference in measurements of the fetal lateral ventricles?

Behrendt N, Zaretsky MV, West NA, Galan HL, Crombleholme TM, Meyers ML.

J Matern Fetal Neonatal Med. 2017 Feb;30(3):298-301. Epub 2016 Apr 19.


Twin-twin transfusion and laser therapy.

Behrendt N, Galan HL.

Curr Opin Obstet Gynecol. 2016 Apr;28(2):79-85. doi: 10.1097/GCO.0000000000000247. Review.


[Merkel cell carcinoma is a rare, aggressive neuroendocrine skin cancer].

Jarjis RD, Mowinckel MS, Behrendt N, Matzen SH.

Ugeskr Laeger. 2015 Nov 9;177(46):V06150535. Danish.


Targeting a novel bone degradation pathway in primary bone cancer by inactivation of the collagen receptor uPARAP/Endo180.

Engelholm LH, Melander MC, Hald A, Persson M, Madsen DH, Jürgensen HJ, Johansson K, Nielsen C, Nørregaard KS, Ingvarsen SZ, Kjaer A, Trovik CS, Laerum OD, Bugge TH, Eide J, Behrendt N.

J Pathol. 2016 Jan;238(1):120-33. doi: 10.1002/path.4661. Epub 2015 Nov 30.


The collagen receptor uPARAP/Endo180 in tissue degradation and cancer (Review).

Melander MC, Jürgensen HJ, Madsen DH, Engelholm LH, Behrendt N.

Int J Oncol. 2015 Oct;47(4):1177-88. doi: 10.3892/ijo.2015.3120. Epub 2015 Aug 12. Review.


Tumor Cell Adhesion As a Risk Factor for Sentinel Lymph Node Metastasis in Primary Cutaneous Melanoma.

Meves A, Nikolova E, Heim JB, Squirewell EJ, Cappel MA, Pittelkow MR, Otley CC, Behrendt N, Saunte DM, Lock-Andersen J, Schenck LA, Weaver AL, Suman VJ.

J Clin Oncol. 2015 Aug 10;33(23):2509-15. doi: 10.1200/JCO.2014.60.7002. Epub 2015 Jul 6.


Sonographic assessment of a pregnancy complicated by a rare presentation of twin reversed arterial perfusion sequence.

Downs EM, Behrendt NJ.

J Ultrasound Med. 2014 Oct;33(10):1865-8. doi: 10.7863/ultra.33.10.1865. No abstract available.


Advances in targeted delivery of small interfering RNA using simple bioconjugates.

Nielsen C, Kjems J, Sørensen KR, Engelholm LH, Behrendt N.

Expert Opin Drug Deliv. 2014 May;11(5):791-822. doi: 10.1517/17425247.2014.896898. Epub 2014 Mar 26. Review.


Matrix metalloproteinase 2 and membrane type 1 matrix metalloproteinase co-regulate axonal outgrowth of mouse retinal ganglion cells.

Gaublomme D, Buyens T, De Groef L, Stakenborg M, Janssens E, Ingvarsen S, Porse A, Behrendt N, Moons L.

J Neurochem. 2014 Jun;129(6):966-79. doi: 10.1111/jnc.12703. Epub 2014 Mar 27.


Complex determinants in specific members of the mannose receptor family govern collagen endocytosis.

Jürgensen HJ, Johansson K, Madsen DH, Porse A, Melander MC, Sørensen KR, Nielsen C, Bugge TH, Behrendt N, Engelholm LH.

J Biol Chem. 2014 Mar 14;289(11):7935-47. doi: 10.1074/jbc.M113.512780. Epub 2014 Feb 5.


A monoclonal antibody interferes with TIMP-2 binding and incapacitates the MMP-2-activating function of multifunctional, pro-tumorigenic MMP-14/MT1-MMP.

Shiryaev SA, Remacle AG, Golubkov VS, Ingvarsen S, Porse A, Behrendt N, Cieplak P, Strongin AY.

Oncogenesis. 2013 Dec 2;2:e80. doi: 10.1038/oncsis.2013.44.


M2-like macrophages are responsible for collagen degradation through a mannose receptor-mediated pathway.

Madsen DH, Leonard D, Masedunskas A, Moyer A, Jürgensen HJ, Peters DE, Amornphimoltham P, Selvaraj A, Yamada SS, Brenner DA, Burgdorf S, Engelholm LH, Behrendt N, Holmbeck K, Weigert R, Bugge TH.

J Cell Biol. 2013 Sep 16;202(6):951-66. doi: 10.1083/jcb.201301081. Epub 2013 Sep 9.


Differential actions of the endocytic collagen receptor uPARAP/Endo180 and the collagenase MMP-2 in bone homeostasis.

Madsen DH, Jürgensen HJ, Ingvarsen S, Melander MC, Albrechtsen R, Hald A, Holmbeck K, Bugge TH, Behrendt N, Engelholm LH.

PLoS One. 2013 Aug 5;8(8):e71261. doi: 10.1371/journal.pone.0071261. Print 2013.


Ficolin-1-PTX3 complex formation promotes clearance of altered self-cells and modulates IL-8 production.

Ma YJ, Doni A, Romani L, Jürgensen HJ, Behrendt N, Mantovani A, Garred P.

J Immunol. 2013 Aug 1;191(3):1324-33. doi: 10.4049/jimmunol.1300382. Epub 2013 Jul 1.


Targeting a single function of the multifunctional matrix metalloprotease MT1-MMP: impact on lymphangiogenesis.

Ingvarsen S, Porse A, Erpicum C, Maertens L, Jürgensen HJ, Madsen DH, Melander MC, Gårdsvoll H, Høyer-Hansen G, Noel A, Holmbeck K, Engelholm LH, Behrendt N.

J Biol Chem. 2013 Apr 12;288(15):10195-204. doi: 10.1074/jbc.M112.447169. Epub 2013 Feb 14.


Rate of change in cervical length in women with vaginal bleeding during pregnancy.

Behrendt N, Gibbs RS, Lynch A, Hart J, West NA, Iams JD.

Obstet Gynecol. 2013 Feb;121(2 Pt 1):260-4. doi: http://10.1097/AOG.0b013e31827d8e1b.


New and paradoxical roles of matrix metalloproteinases in the tumor microenvironment.

Noël A, Gutiérrez-Fernández A, Sounni NE, Behrendt N, Maquoi E, Lund IK, Cal S, Hoyer-Hansen G, López-Otín C.

Front Pharmacol. 2012 Jul 17;3:140. doi: 10.3389/fphar.2012.00140. eCollection 2012.


Inhibitory Monoclonal Antibodies against Mouse Proteases Raised in Gene-Deficient Mice Block Proteolytic Functions in vivo.

Lund IK, Rasch MG, Ingvarsen S, Pass J, Madsen DH, Engelholm LH, Behrendt N, Høyer-Hansen G.

Front Pharmacol. 2012 Jun 28;3:122. doi: 10.3389/fphar.2012.00122. eCollection 2012.


Endocytic collagen degradation: a novel mechanism involved in protection against liver fibrosis.

Madsen DH, Jürgensen HJ, Ingvarsen S, Melander MC, Vainer B, Egerod KL, Hald A, Rønø B, Madsen CA, Bugge TH, Engelholm LH, Behrendt N.

J Pathol. 2012 May;227(1):94-105. doi: 10.1002/path.3981. Epub 2012 Feb 17.


The rate of cervical change and the phenotype of spontaneous preterm birth.

Iams JD, Cebrik D, Lynch C, Behrendt N, Das A.

Am J Obstet Gynecol. 2011 Aug;205(2):130.e1-6. doi: 10.1016/j.ajog.2011.05.021. Epub 2011 May 14.


Treatment influencing down-staging in EORTC Melanoma Group sentinel node histological protocol compared with complete step-sectioning: a national multicentre study.

Riber-Hansen R, Hastrup N, Clemmensen O, Behrendt N, Klausen S, Ramsing M, Spaun E, Hamilton-Dutoit SJ, Steiniche T.

Eur J Cancer. 2012 Feb;48(3):347-52. doi: 10.1016/j.ejca.2011.08.019. Epub 2011 Oct 22.


Conformational regulation of urokinase receptor function: impact of receptor occupancy and epitope-mapped monoclonal antibodies on lamellipodia induction.

Gårdsvoll H, Jacobsen B, Kriegbaum MC, Behrendt N, Engelholm L, Østergaard S, Ploug M.

J Biol Chem. 2011 Sep 23;286(38):33544-56. doi: 10.1074/jbc.M111.220087. Epub 2011 Jul 28.


A novel functional role of collagen glycosylation: interaction with the endocytic collagen receptor uparap/ENDO180.

Jürgensen HJ, Madsen DH, Ingvarsen S, Melander MC, Gårdsvoll H, Patthy L, Engelholm LH, Behrendt N.

J Biol Chem. 2011 Sep 16;286(37):32736-48. doi: 10.1074/jbc.M111.266692. Epub 2011 Jul 18.


The non-phagocytic route of collagen uptake: a distinct degradation pathway.

Madsen DH, Ingvarsen S, Jürgensen HJ, Melander MC, Kjøller L, Moyer A, Honoré C, Madsen CA, Garred P, Burgdorf S, Bugge TH, Behrendt N, Engelholm LH.

J Biol Chem. 2011 Jul 29;286(30):26996-7010. doi: 10.1074/jbc.M110.208033. Epub 2011 Jun 7.


MyMiCROscope: intelligent virtual microscopy in a blended learning model at Ulm University.

Schmidt C, Reinehr M, Leucht O, Behrendt N, Geiler S, Britsch S.

Ann Anat. 2011 Oct 20;193(5):395-402. doi: 10.1016/j.aanat.2011.04.009. Epub 2011 May 13.


Influence of maternal body mass index and gestational age on accuracy of first trimester gender assignment.

Behrendt N, Foy P, Center J, Durnwald CP.

J Matern Fetal Neonatal Med. 2012 Mar;25(3):253-6. doi: 10.3109/14767058.2011.569616. Epub 2011 Apr 18.


[Sarcomatoid mesothelioma--a diagnostic challenge].

Eiholm S, Meyer CN, Behrendt N.

Ugeskr Laeger. 2010 Sep 27;172(39):2670-1. Danish.


Assessing early vascular changes and treatment response after laser-induced thermotherapy of pulmonary metastases with perfusion CT: initial experience.

Hegenscheid K, Behrendt N, Rosenberg C, Kuehn JP, Ewert R, Hosten N, Puls R.

AJR Am J Roentgenol. 2010 Apr;194(4):1116-23. doi: 10.2214/AJR.09.2810.


Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity.

Morsy H, Kamp S, Thrane L, Behrendt N, Saunder B, Zayan H, Elmagid EA, Jemec GB.

Arch Dermatol Res. 2010 Mar;302(2):105-11. doi: 10.1007/s00403-009-1000-4. Epub 2009 Nov 6.


Differential p53-independent outcomes of p19(Arf) loss in oncogenesis.

Chen Z, Carracedo A, Lin HK, Koutcher JA, Behrendt N, Egia A, Alimonti A, Carver BS, Gerald W, Teruya-Feldstein J, Loda M, Pandolfi PP.

Sci Signal. 2009 Aug 18;2(84):ra44. doi: 10.1126/scisignal.2000053.

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