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Items: 23


QTL Mapping and CRISPR/Cas9 Editing to Identify a Drug Resistance Gene in Toxoplasma gondii.

Shen B, Powell RH, Behnke MS.

J Vis Exp. 2017 Jun 22;(124). doi: 10.3791/55185.


Genetic Mapping of Pathogenesis Determinants in Toxoplasma gondii.

Behnke MS, Dubey JP, Sibley LD.

Annu Rev Microbiol. 2016 Sep 8;70:63-81. doi: 10.1146/annurev-micro-091014-104353. Epub 2016 Jun 17. Review.


The Past, Present, and Future of Genetic Manipulation in Toxoplasma gondii.

Wang JL, Huang SY, Behnke MS, Chen K, Shen B, Zhu XQ.

Trends Parasitol. 2016 Jul;32(7):542-553. doi: 10.1016/ Epub 2016 May 12. Review.


Local admixture of amplified and diversified secreted pathogenesis determinants shapes mosaic Toxoplasma gondii genomes.

Lorenzi H, Khan A, Behnke MS, Namasivayam S, Swapna LS, Hadjithomas M, Karamycheva S, Pinney D, Brunk BP, Ajioka JW, Ajzenberg D, Boothroyd JC, Boyle JP, Dardé ML, Diaz-Miranda MA, Dubey JP, Fritz HM, Gennari SM, Gregory BD, Kim K, Saeij JP, Su C, White MW, Zhu XQ, Howe DK, Rosenthal BM, Grigg ME, Parkinson J, Liu L, Kissinger JC, Roos DS, Sibley LD.

Nat Commun. 2016 Jan 7;7:10147. doi: 10.1038/ncomms10147.


Rhoptry Proteins ROP5 and ROP18 Are Major Murine Virulence Factors in Genetically Divergent South American Strains of Toxoplasma gondii.

Behnke MS, Khan A, Lauron EJ, Jimah JR, Wang Q, Tolia NH, Sibley LD.

PLoS Genet. 2015 Aug 20;11(8):e1005434. doi: 10.1371/journal.pgen.1005434. eCollection 2015 Aug.


Add Bryant to the protocol.

Behnke MS, Bloomberg B, Olson S.

Lab Anim (NY). 2015 Aug;44(8):295-6. doi: 10.1038/laban.822. No abstract available.


miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain.

Cannella D, Brenier-Pinchart MP, Braun L, van Rooyen JM, Bougdour A, Bastien O, Behnke MS, Curt RL, Curt A, Saeij JP, Sibley LD, Pelloux H, Hakimi MA.

Cell Rep. 2014 Mar 13;6(5):928-37. doi: 10.1016/j.celrep.2014.02.002. Epub 2014 Feb 27.


The polymorphic pseudokinase ROP5 controls virulence in Toxoplasma gondii by regulating the active kinase ROP18.

Behnke MS, Fentress SJ, Mashayekhi M, Li LX, Taylor GA, Sibley LD.

PLoS Pathog. 2012;8(11):e1002992. doi: 10.1371/journal.ppat.1002992. Epub 2012 Nov 8.


A systematic screen to discover and analyze apicoplast proteins identifies a conserved and essential protein import factor.

Sheiner L, Demerly JL, Poulsen N, Beatty WL, Lucas O, Behnke MS, White MW, Striepen B.

PLoS Pathog. 2011 Dec;7(12):e1002392. doi: 10.1371/journal.ppat.1002392. Epub 2011 Dec 1.


Virulence differences in Toxoplasma mediated by amplification of a family of polymorphic pseudokinases.

Behnke MS, Khan A, Wootton JC, Dubey JP, Tang K, Sibley LD.

Proc Natl Acad Sci U S A. 2011 Jun 7;108(23):9631-6. doi: 10.1073/pnas.1015338108. Epub 2011 May 17.


Cell cycle-dependent, intercellular transmission of Toxoplasma gondii is accompanied by marked changes in parasite gene expression.

Gaji RY, Behnke MS, Lehmann MM, White MW, Carruthers VB.

Mol Microbiol. 2011 Jan;79(1):192-204. doi: 10.1111/j.1365-2958.2010.07441.x. Epub 2010 Nov 9.


Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence.

Fentress SJ, Behnke MS, Dunay IR, Mashayekhi M, Rommereim LM, Fox BA, Bzik DJ, Taylor GA, Turk BE, Lichti CF, Townsend RR, Qiu W, Hui R, Beatty WL, Sibley LD.

Cell Host Microbe. 2010 Dec 16;8(6):484-95. doi: 10.1016/j.chom.2010.11.005.


T. gondii RP promoters & knockdown reveal molecular pathways associated with proliferation and cell-cycle arrest.

Hutson SL, Mui E, Kinsley K, Witola WH, Behnke MS, El Bissati K, Muench SP, Rohrman B, Liu SR, Wollmann R, Ogata Y, Sarkeshik A, Yates JR 3rd, McLeod R.

PLoS One. 2010 Nov 22;5(11):e14057. doi: 10.1371/journal.pone.0014057.


Coordinated progression through two subtranscriptomes underlies the tachyzoite cycle of Toxoplasma gondii.

Behnke MS, Wootton JC, Lehmann MM, Radke JB, Lucas O, Nawas J, Sibley LD, White MW.

PLoS One. 2010 Aug 26;5(8):e12354. doi: 10.1371/journal.pone.0012354.


Phenotypic and gene expression changes among clonal type I strains of Toxoplasma gondii.

Khan A, Behnke MS, Dunay IR, White MW, Sibley LD.

Eukaryot Cell. 2009 Dec;8(12):1828-36. doi: 10.1128/EC.00150-09. Epub 2009 Oct 2.


The transcription of bradyzoite genes in Toxoplasma gondii is controlled by autonomous promoter elements.

Behnke MS, Radke JB, Smith AT, Sullivan WJ Jr, White MW.

Mol Microbiol. 2008 Jun;68(6):1502-18. doi: 10.1111/j.1365-2958.2008.06249.x. Epub 2008 Apr 21.


A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii.

Taylor S, Barragan A, Su C, Fux B, Fentress SJ, Tang K, Beatty WL, Hajj HE, Jerome M, Behnke MS, White M, Wootton JC, Sibley LD.

Science. 2006 Dec 15;314(5806):1776-80.


Changes in the expression of human cell division autoantigen-1 influence Toxoplasma gondii growth and development.

Radke JR, Donald RG, Eibs A, Jerome ME, Behnke MS, Liberator P, White MW.

PLoS Pathog. 2006 Oct;2(10):e105.


The transcriptome of Toxoplasma gondii.

Radke JR, Behnke MS, Mackey AJ, Radke JB, Roos DS, White MW.

BMC Biol. 2005 Dec 2;3:26.


Biochemical and genetic analysis of the distinct proliferating cell nuclear antigens of Toxoplasma gondii.

Guerini MN, Behnke MS, White MW.

Mol Biochem Parasitol. 2005 Jul;142(1):56-65. Epub 2005 Apr 21.


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