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Items: 40


Innovative Therapy for Alzheimer's Disease-With Focus on Biodelivery of NGF.

Mitra S, Behbahani H, Eriksdotter M.

Front Neurosci. 2019 Feb 5;13:38. doi: 10.3389/fnins.2019.00038. eCollection 2019. Review.


Autophagy-lysosomal defect in human CADASIL vascular smooth muscle cells.

Hanemaaijer ES, Panahi M, Swaddiwudhipong N, Tikka S, Winblad B, Viitanen M, Piras A, Behbahani H.

Eur J Cell Biol. 2018 Nov;97(8):557-567. doi: 10.1016/j.ejcb.2018.10.001. Epub 2018 Oct 22.


Increased Active OMI/HTRA2 Serine Protease Displays a Positive Correlation with Cholinergic Alterations in the Alzheimer's Disease Brain.

Darreh-Shori T, Rezaeianyazdi S, Lana E, Mitra S, Gellerbring A, Karami A, Bogdanovic N, Lithner CU, Winblad B, Behbahani H.

Mol Neurobiol. 2019 Jul;56(7):4601-4619. doi: 10.1007/s12035-018-1383-3. Epub 2018 Oct 25.


Cerebrospinal fluid from Alzheimer patients affects cell-mediated nerve growth factor production and cell survival in vitro.

Eriksdotter M, Navarro-Oviedo M, Mitra S, Wahlberg L, Linderoth B, Tjernberg LO, Behbahani H.

Exp Cell Res. 2018 Oct 1;371(1):175-184. doi: 10.1016/j.yexcr.2018.08.007. Epub 2018 Aug 6.


You can't fix what isn't broken: eight weeks of exercise do not substantially change cognitive function and biochemical markers in young and healthy adults.

Gourgouvelis J, Yielder P, Clarke ST, Behbahani H, Murphy B.

PeerJ. 2018 Apr 19;6:e4675. doi: 10.7717/peerj.4675. eCollection 2018.


Exercise Leads to Better Clinical Outcomes in Those Receiving Medication Plus Cognitive Behavioral Therapy for Major Depressive Disorder.

Gourgouvelis J, Yielder P, Clarke ST, Behbahani H, Murphy BA.

Front Psychiatry. 2018 Mar 6;9:37. doi: 10.3389/fpsyt.2018.00037. eCollection 2018.


Differences in proliferation rate between CADASIL and control vascular smooth muscle cells are related to increased TGFβ expression.

Panahi M, Yousefi Mesri N, Samuelsson EB, Coupland KG, Forsell C, Graff C, Tikka S, Winblad B, Viitanen M, Karlström H, Sundström E, Behbahani H.

J Cell Mol Med. 2018 Jun;22(6):3016-3024. doi: 10.1111/jcmm.13534. Epub 2018 Mar 13.


Abnormal heart-rate response during cardiopulmonary exercise testing identifies cardiac dysfunction in symptomatic patients with non-obstructive coronary artery disease.

Chaudhry S, Kumar N, Behbahani H, Bagai A, Singh BK, Menasco N, Lewis GD, Sperling L, Myers J.

Int J Cardiol. 2017 Feb 1;228:114-121. doi: 10.1016/j.ijcard.2016.11.235. Epub 2016 Nov 14.


Inverse relationship between erythrocyte size and platelet reactivity in elderly.

Milovanovic M, Nilsson S, Winblad B, Jelic V, Behbahani H, Shahnaz T, Oweling M, Järemo P.

Platelets. 2017 Mar;28(2):182-186. doi: 10.1080/09537104.2016.1206196. Epub 2016 Aug 24.


Association of Platelet Serotonin Levels in Alzheimer's Disease with Clinical and Cerebrospinal Fluid Markers.

Tajeddinn W, Fereshtehnejad SM, Seed Ahmed M, Yoshitake T, Kehr J, Shahnaz T, Milovanovic M, Behbahani H, Höglund K, Winblad B, Cedazo-Minguez A, Jelic V, Järemo P, Aarsland D.

J Alzheimers Dis. 2016 May 4;53(2):621-30. doi: 10.3233/JAD-160022.


Perforin Promotes Amyloid Beta Internalisation in Neurons.

Lana E, Khanbolouki M, Degavre C, Samuelsson EB, Åkesson E, Winblad B, Alici E, Lithner CU, Behbahani H.

Mol Neurobiol. 2017 Mar;54(2):874-887. doi: 10.1007/s12035-016-9685-9. Epub 2016 Jan 16.


Mitochondrial dysfunction in a transgenic mouse model expressing human amyloid precursor protein (APP) with the Arctic mutation.

Rönnbäck A, Pavlov PF, Mansory M, Gonze P, Marlière N, Winblad B, Graff C, Behbahani H.

J Neurochem. 2016 Feb;136(3):497-502. doi: 10.1111/jnc.13410. Epub 2015 Nov 19.


Stress Conditions Increase Vimentin Cleavage by Omi/HtrA2 Protease in Human Primary Neurons and Differentiated Neuroblastoma Cells.

Lucotte B, Tajhizi M, Alkhatib D, Samuelsson EB, Wiehager B, Schedin-Weiss S, Sundström E, Winblad B, Tjernberg LO, Behbahani H.

Mol Neurobiol. 2015 Dec;52(3):1077-1092. doi: 10.1007/s12035-014-8906-3. Epub 2014 Oct 8.


A novel protocol to investigate motor training-induced plasticity and sensorimotor integration in the cerebellum and motor cortex.

Baarbé J, Yielder P, Daligadu J, Behbahani H, Haavik H, Murphy B.

J Neurophysiol. 2014 Feb;111(4):715-21. doi: 10.1152/jn.00661.2013. Epub 2013 Nov 20.


Regulated Extracellular Choline Acetyltransferase Activity- The Plausible Missing Link of the Distant Action of Acetylcholine in the Cholinergic Anti-Inflammatory Pathway.

Vijayaraghavan S, Karami A, Aeinehband S, Behbahani H, Grandien A, Nilsson B, Ekdahl KN, Lindblom RP, Piehl F, Darreh-Shori T.

PLoS One. 2013 Jun 19;8(6):e65936. doi: 10.1371/journal.pone.0065936. Print 2013.


Modulation of the endoplasmic reticulum-mitochondria interface in Alzheimer's disease and related models.

Hedskog L, Pinho CM, Filadi R, Rönnbäck A, Hertwig L, Wiehager B, Larssen P, Gellhaar S, Sandebring A, Westerlund M, Graff C, Winblad B, Galter D, Behbahani H, Pizzo P, Glaser E, Ankarcrona M.

Proc Natl Acad Sci U S A. 2013 May 7;110(19):7916-21. doi: 10.1073/pnas.1300677110. Epub 2013 Apr 25.


Experimental studies of mitochondrial function in CADASIL vascular smooth muscle cells.

Viitanen M, Sundström E, Baumann M, Poyhonen M, Tikka S, Behbahani H.

Exp Cell Res. 2013 Feb 1;319(3):134-43. doi: 10.1016/j.yexcr.2012.09.015. Epub 2012 Oct 1.


Erlin-2 is associated with active γ-secretase in brain and affects amyloid β-peptide production.

Teranishi Y, Hur JY, Gu GJ, Kihara T, Ishikawa T, Nishimura T, Winblad B, Behbahani H, Kamali-Moghaddam M, Frykman S, Tjernberg LO.

Biochem Biophys Res Commun. 2012 Aug 3;424(3):476-81. doi: 10.1016/j.bbrc.2012.06.137. Epub 2012 Jul 4.


Amyloid precursor protein accumulates in aggresomes in response to proteasome inhibitor.

Dehvari N, Mahmud T, Persson J, Bengtsson T, Graff C, Winblad B, Rönnbäck A, Behbahani H.

Neurochem Int. 2012 Apr;60(5):533-42. doi: 10.1016/j.neuint.2012.02.012. Epub 2012 Feb 15.


Altered enzymatic activity and allele frequency of OMI/HTRA2 in Alzheimer's disease.

Westerlund M, Behbahani H, Gellhaar S, Forsell C, Belin AC, Anvret A, Zettergren A, Nissbrandt H, Lind C, Sydow O, Graff C, Olson L, Ankarcrona M, Galter D.

FASEB J. 2011 Apr;25(4):1345-52. doi: 10.1096/fj.10-163402. Epub 2010 Dec 16.


Mitochondrial γ-secretase participates in the metabolism of mitochondria-associated amyloid precursor protein.

Pavlov PF, Wiehager B, Sakai J, Frykman S, Behbahani H, Winblad B, Ankarcrona M.

FASEB J. 2011 Jan;25(1):78-88. doi: 10.1096/fj.10-157230. Epub 2010 Sep 10.


Association of Omi/HtrA2 with γ-secretase in mitochondria.

Behbahani H, Pavlov PF, Wiehager B, Nishimura T, Winblad B, Ankarcrona M.

Neurochem Int. 2010 Nov;57(6):668-75. doi: 10.1016/j.neuint.2010.08.004. Epub 2010 Aug 10.


Synaptic and endosomal localization of active gamma-secretase in rat brain.

Frykman S, Hur JY, Frånberg J, Aoki M, Winblad B, Nahalkova J, Behbahani H, Tjernberg LO.

PLoS One. 2010 Jan 28;5(1):e8948. doi: 10.1371/journal.pone.0008948.


CD147, a gamma-secretase associated protein is upregulated in Alzheimer's disease brain and its cellular trafficking is affected by presenilin-2.

Nahalkova J, Volkmann I, Aoki M, Winblad B, Bogdanovic N, Tjernberg LO, Behbahani H.

Neurochem Int. 2010 Jan;56(1):67-76. doi: 10.1016/j.neuint.2009.09.003. Epub 2009 Sep 12.


Mitochondrial alterations in PINK1 deficient cells are influenced by calcineurin-dependent dephosphorylation of dynamin-related protein 1.

Sandebring A, Thomas KJ, Beilina A, van der Brug M, Cleland MM, Ahmad R, Miller DW, Zambrano I, Cowburn RF, Behbahani H, Cedazo-Mínguez A, Cookson MR.

PLoS One. 2009 May 27;4(5):e5701. doi: 10.1371/journal.pone.0005701.


The amyloid beta-peptide is imported into mitochondria via the TOM import machinery and localized to mitochondrial cristae.

Hansson Petersen CA, Alikhani N, Behbahani H, Wiehager B, Pavlov PF, Alafuzoff I, Leinonen V, Ito A, Winblad B, Glaser E, Ankarcrona M.

Proc Natl Acad Sci U S A. 2008 Sep 2;105(35):13145-50. doi: 10.1073/pnas.0806192105. Epub 2008 Aug 29.


Active gamma-secretase is localized to detergent-resistant membranes in human brain.

Hur JY, Welander H, Behbahani H, Aoki M, Frånberg J, Winblad B, Frykman S, Tjernberg LO.

FEBS J. 2008 Mar;275(6):1174-87. doi: 10.1111/j.1742-4658.2008.06278.x. Epub 2008 Feb 6.


Leukemia inhibitor factor (LIF) inhibits HIV-1 replication via restriction of stat 3 activation.

Tjernlund A, Walther-Jallow L, Behbahani H, Screpanti V, Nowak P, Grandien A, Andersson J, Patterson BK.

AIDS Res Hum Retroviruses. 2007 Mar;23(3):398-406.


Proinflammatory and type 1 cytokine expression in cervical mucosa during HIV-1 and human papillomavirus infection.

Behbahani H, Walther-Jallow L, Klareskog E, Baum L, French AL, Patterson BK, Garcia P, Spetz AL, Landay A, Andersson J.

J Acquir Immune Defic Syndr. 2007 May 1;45(1):9-19.


Differential role of Presenilin-1 and -2 on mitochondrial membrane potential and oxygen consumption in mouse embryonic fibroblasts.

Behbahani H, Shabalina IG, Wiehager B, Concha H, Hultenby K, Petrovic N, Nedergaard J, Winblad B, Cowburn RF, Ankarcrona M.

J Neurosci Res. 2006 Sep;84(4):891-902.


PTEN, Akt, and GSK3beta signalling in rat primary cortical neuronal cultures following tumor necrosis factor-alpha and trans-4-hydroxy-2-nonenal treatments.

Rickle A, Behbahani H, Ankarcrona M, Winblad B, Cowburn RF.

J Neurosci Res. 2006 Aug 15;84(3):596-605.


Flow cytometry as a method for studying effects of stressors on primary rat neurons.

Behbahani H, Rickle A, Concha H, Ankarcrona M, Winblad B, Cowburn RF.

J Neurosci Res. 2005 Nov 1;82(3):432-41.


Suppression of leukemia inhibitor factor in lymphoid tissue in primary HIV infection: absence of HIV replication in gp130-positive cells.

Tjernlund A, Fleener Z, Behbahani H, Connick E, Sönnerborg A, Broström C, Goh LE, Spetz AL, Patterson BK, Andersson J.

AIDS. 2003 Jun 13;17(9):1303-10.


Low levels of perforin expression in CD8+ T lymphocyte granules in lymphoid tissue during acute human immunodeficiency virus type 1 infection.

Andersson J, Kinloch S, Sönnerborg A, Nilsson J, Fehniger TE, Spetz AL, Behbahani H, Goh LE, McDade H, Gazzard B, Stellbrink H, Cooper D, Perrin L.

J Infect Dis. 2002 May 1;185(9):1355-8. Epub 2002 Apr 16.


Leukemia inhibitory factor inhibits HIV-1 replication and is upregulated in placentae from nontransmitting women.

Patterson BK, Behbahani H, Kabat WJ, Sullivan Y, O'Gorman MR, Landay A, Flener Z, Khan N, Yogev R, Andersson J.

J Clin Invest. 2001 Feb;107(3):287-94.


Up-regulation of CCR5 expression in the placenta is associated with human immunodeficiency virus-1 vertical transmission.

Behbahani H, Popek E, Garcia P, Andersson J, Spetz AL, Landay A, Flener Z, Patterson BK.

Am J Pathol. 2000 Dec;157(6):1811-8.


Normalization of immune activation in lymphoid tissue following highly active antiretroviral therapy.

Behbahani H, Landay A, Patterson BK, Jones P, Pottage J, Agnoli M, Andersson J, Spetz AL.

J Acquir Immune Defic Syndr. 2000 Oct 1;25(2):150-6.


Perforin is not co-expressed with granzyme A within cytotoxic granules in CD8 T lymphocytes present in lymphoid tissue during chronic HIV infection.

Andersson J, Behbahani H, Lieberman J, Connick E, Landay A, Patterson B, Sönnerborg A, Loré K, Uccini S, Fehniger TE.

AIDS. 1999 Jul 30;13(11):1295-303.


Repertoire of chemokine receptor expression in the female genital tract: implications for human immunodeficiency virus transmission.

Patterson BK, Landay A, Andersson J, Brown C, Behbahani H, Jiyamapa D, Burki Z, Stanislawski D, Czerniewski MA, Garcia P.

Am J Pathol. 1998 Aug;153(2):481-90.


Early reduction of immune activation in lymphoid tissue following highly active HIV therapy.

Andersson J, Fehniger TE, Patterson BK, Pottage J, Agnoli M, Jones P, Behbahani H, Landay A.

AIDS. 1998 Jul 30;12(11):F123-9.


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