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Items: 22

1.

Dietary palmitate cooperates with Src kinase to promote prostate tumor progression.

Kim S, Yang X, Yin A, Zha J, Beharry Z, Bai A, Bielawska A, Bartlett MG, Yin H, Cai H.

Prostate. 2019 Jun;79(8):896-908. doi: 10.1002/pros.23796. Epub 2019 Mar 22.

PMID:
30900312
2.

Stromal Gli signaling regulates the activity and differentiation of prostate stem and progenitor cells.

Li Q, Alsaidan OA, Rai S, Wu M, Shen H, Beharry Z, Almada LL, Fernandez-Zapico ME, Wang L, Cai H.

J Biol Chem. 2018 Jul 6;293(27):10547-10560. doi: 10.1074/jbc.RA118.003255. Epub 2018 May 17.

3.

Pharmacologically targeting the myristoylation of the scaffold protein FRS2α inhibits FGF/FGFR-mediated oncogenic signaling and tumor progression.

Li Q, Alsaidan OA, Ma Y, Kim S, Liu J, Albers T, Liu K, Beharry Z, Zhao S, Wang F, Lebedyeva I, Cai H.

J Biol Chem. 2018 Apr 27;293(17):6434-6448. doi: 10.1074/jbc.RA117.000940. Epub 2018 Mar 14.

4.

Paracrine Fibroblast Growth Factor Initiates Oncogenic Synergy with Epithelial FGFR/Src Transformation in Prostate Tumor Progression.

Li Q, Ingram L, Kim S, Beharry Z, Cooper JA, Cai H.

Neoplasia. 2018 Mar;20(3):233-243. doi: 10.1016/j.neo.2018.01.006. Epub 2018 Feb 11.

5.

Blocking Myristoylation of Src Inhibits Its Kinase Activity and Suppresses Prostate Cancer Progression.

Kim S, Alsaidan OA, Goodwin O, Li Q, Sulejmani E, Han Z, Bai A, Albers T, Beharry Z, Zheng YG, Norris JS, Szulc ZM, Bielawska A, Lebedyeva I, Pegan SD, Cai H.

Cancer Res. 2017 Dec 15;77(24):6950-6962. doi: 10.1158/0008-5472.CAN-17-0981. Epub 2017 Oct 16.

6.

Myristoylation of Src kinase mediates Src-induced and high-fat diet-accelerated prostate tumor progression in mice.

Kim S, Yang X, Li Q, Wu M, Costyn L, Beharry Z, Bartlett MG, Cai H.

J Biol Chem. 2017 Nov 10;292(45):18422-18433. doi: 10.1074/jbc.M117.798827. Epub 2017 Sep 22.

7.

Gli Transcription Factors Mediate the Oncogenic Transformation of Prostate Basal Cells Induced by a Kras-Androgen Receptor Axis.

Wu M, Ingram L, Tolosa EJ, Vera RE, Li Q, Kim S, Ma Y, Spyropoulos DD, Beharry Z, Huang J, Fernandez-Zapico ME, Cai H.

J Biol Chem. 2016 Dec 2;291(49):25749-25760. Epub 2016 Oct 19.

8.

Collaboration of Kras and androgen receptor signaling stimulates EZH2 expression and tumor-propagating cells in prostate cancer.

Cai H, Memarzadeh S, Stoyanova T, Beharry Z, Kraft AS, Witte ON.

Cancer Res. 2012 Sep 15;72(18):4672-81. Epub 2012 Jul 17.

9.

The Pim protein kinases regulate energy metabolism and cell growth.

Beharry Z, Mahajan S, Zemskova M, Lin YW, Tholanikunnel BG, Xia Z, Smith CD, Kraft AS.

Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):528-33. doi: 10.1073/pnas.1013214108. Epub 2010 Dec 27.

10.

Regulation of Skp2 levels by the Pim-1 protein kinase.

Cen B, Mahajan S, Zemskova M, Beharry Z, Lin YW, Cramer SD, Lilly MB, Kraft AS.

J Biol Chem. 2010 Sep 17;285(38):29128-37. doi: 10.1074/jbc.M110.137240. Epub 2010 Jul 27.

11.

A small molecule inhibitor of Pim protein kinases blocks the growth of precursor T-cell lymphoblastic leukemia/lymphoma.

Lin YW, Beharry ZM, Hill EG, Song JH, Wang W, Xia Z, Zhang Z, Aplan PD, Aster JC, Smith CD, Kraft AS.

Blood. 2010 Jan 28;115(4):824-33. doi: 10.1182/blood-2009-07-233445. Epub 2009 Nov 23.

12.

Novel benzylidene-thiazolidine-2,4-diones inhibit Pim protein kinase activity and induce cell cycle arrest in leukemia and prostate cancer cells.

Beharry Z, Zemskova M, Mahajan S, Zhang F, Ma J, Xia Z, Lilly M, Smith CD, Kraft AS.

Mol Cancer Ther. 2009 Jun;8(6):1473-83. doi: 10.1158/1535-7163.MCT-08-1037. Epub 2009 Jun 9.

13.

PIM1 protein kinase regulates PRAS40 phosphorylation and mTOR activity in FDCP1 cells.

Zhang F, Beharry ZM, Harris TE, Lilly MB, Smith CD, Mahajan S, Kraft AS.

Cancer Biol Ther. 2009 May;8(9):846-53. Epub 2009 May 18.

PMID:
19276681
14.

Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases.

Xia Z, Knaak C, Ma J, Beharry ZM, McInnes C, Wang W, Kraft AS, Smith CD.

J Med Chem. 2009 Jan 8;52(1):74-86. doi: 10.1021/jm800937p.

15.

Epitope mapping and use of epitope-specific antisera to characterize the VP5* binding site in rotavirus SA11 NSP4.

Hyser JM, Zeng CQ, Beharry Z, Palzkill T, Estes MK.

Virology. 2008 Mar 30;373(1):211-28. doi: 10.1016/j.virol.2007.11.021. Epub 2007 Dec 31.

16.

Functional analysis of active site residues of the fosfomycin resistance enzyme FosA from Pseudomonas aeruginosa.

Beharry Z, Palzkill T.

J Biol Chem. 2005 May 6;280(18):17786-91. Epub 2005 Mar 1.

17.

Analysis of the context dependent sequence requirements of active site residues in the metallo-beta-lactamase IMP-1.

Materon IC, Beharry Z, Huang W, Perez C, Palzkill T.

J Mol Biol. 2004 Nov 26;344(3):653-63.

PMID:
15533435
18.

Evaluation of penicillin-based inhibitors of the class A and B beta-lactamases from Bacillus anthracis.

Beharry Z, Chen H, Gadhachanda VR, Buynak JD, Palzkill T.

Biochem Biophys Res Commun. 2004 Jan 16;313(3):541-5.

PMID:
14697223
19.

A broad-spectrum peptide inhibitor of beta-lactamase identified using phage display and peptide arrays.

Huang W, Beharry Z, Zhang Z, Palzkill T.

Protein Eng. 2003 Nov;16(11):853-60.

PMID:
14631075
20.

Histidine ligand protonation and redox potential in the rieske dioxygenases: role of a conserved aspartate in anthranilate 1,2-dioxygenase.

Beharry ZM, Eby DM, Coulter ED, Viswanathan R, Neidle EL, Phillips RS, Kurtz DM Jr.

Biochemistry. 2003 Nov 25;42(46):13625-36.

PMID:
14622009
21.

X-ray crystal structure of benzoate 1,2-dioxygenase reductase from Acinetobacter sp. strain ADP1.

Karlsson A, Beharry ZM, Matthew Eby D, Coulter ED, Neidle EL, Kurtz DM Jr, Eklund H, Ramaswamy S.

J Mol Biol. 2002 Apr 26;318(2):261-72.

PMID:
12051836
22.

Characterization and evolution of anthranilate 1,2-dioxygenase from Acinetobacter sp. strain ADP1.

Eby DM, Beharry ZM, Coulter ED, Kurtz DM Jr, Neidle EL.

J Bacteriol. 2001 Jan;183(1):109-18.

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