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Items: 1 to 50 of 169

1.

Prep1 regulates angiogenesis through a PGC-1α-mediated mechanism.

Cimmino I, Margheri F, Prisco F, Perruolo G, D'Esposito V, Laurenzana A, Fibbi G, Paciello O, Doti N, Ruvo M, Miele C, Beguinot F, Formisano P, Oriente F.

FASEB J. 2019 Oct 15:fj201901230RR. doi: 10.1096/fj.201901230RR. [Epub ahead of print]

PMID:
31618597
2.

Low Dose Bisphenol-A Regulates Inflammatory Cytokines through GPR30 in Mammary Adipose Cells.

Cimmino I, Oriente F, D'Esposito V, Liguoro D, Liguoro P, Ambrosio MR, Cabaro S, D'Andrea F, Beguinot F, Formisano P, Valentino R.

J Mol Endocrinol. 2019 Sep 1. pii: JME-18-0265.R4. doi: 10.1530/JME-18-0265. [Epub ahead of print]

PMID:
31546233
3.

The Relevance of Insulin Action in the Dopaminergic System.

Fiory F, Perruolo G, Cimmino I, Cabaro S, Pignalosa FC, Miele C, Beguinot F, Formisano P, Oriente F.

Front Neurosci. 2019 Aug 16;13:868. doi: 10.3389/fnins.2019.00868. eCollection 2019. Review.

4.

KCTD1: A novel modulator of adipogenesis through the interaction with the transcription factor AP2α.

Pirone L, Smaldone G, Spinelli R, Barberisi M, Beguinot F, Vitagliano L, Miele C, Di Gaetano S, Raciti GA, Pedone E.

Biochim Biophys Acta Mol Cell Biol Lipids. 2019 Dec;1864(12):158514. doi: 10.1016/j.bbalip.2019.08.010. Epub 2019 Aug 26.

PMID:
31465887
5.

Dicarbonyl Stress at the Crossroads of Healthy and Unhealthy Aging.

Nigro C, Leone A, Fiory F, Prevenzano I, Nicolò A, Mirra P, Beguinot F, Miele C.

Cells. 2019 Jul 19;8(7). pii: E749. doi: 10.3390/cells8070749. Review.

6.

Nutritional Factors, DNA Methylation, and Risk of Type 2 Diabetes and Obesity: Perspectives and Challenges.

Parrillo L, Spinelli R, Nicolò A, Longo M, Mirra P, Raciti GA, Miele C, Beguinot F.

Int J Mol Sci. 2019 Jun 19;20(12). pii: E2983. doi: 10.3390/ijms20122983. Review.

7.

Quercetin and its derivative Q2 modulate chromatin dynamics in adipogenesis and Q2 prevents obesity and metabolic disorders in rats.

Nettore IC, Rocca C, Mancino G, Albano L, Amelio D, Grande F, Puoci F, Pasqua T, Desiderio S, Mazza R, Terracciano D, Colao A, Bèguinot F, Russo GL, Dentice M, Macchia PE, Sinicropi MS, Angelone T, Ungaro P.

J Nutr Biochem. 2019 Jul;69:151-162. doi: 10.1016/j.jnutbio.2019.03.019. Epub 2019 Apr 8.

PMID:
31096072
8.

Adipose Tissue Dysfunction as Determinant of Obesity-Associated Metabolic Complications.

Longo M, Zatterale F, Naderi J, Parrillo L, Formisano P, Raciti GA, Beguinot F, Miele C.

Int J Mol Sci. 2019 May 13;20(9). pii: E2358. doi: 10.3390/ijms20092358. Review.

9.

Falsely elevated thyroglobulin and calcitonin due to rheumatoid factor in non-relapsing thyroid carcinoma: A case report.

Lupoli GA, Barba L, Liotti A, La Civita E, Lupoli R, Riccio E, Portella G, Formisano P, Beguinot F, Terracciano D.

Medicine (Baltimore). 2019 Feb;98(5):e14178. doi: 10.1097/MD.0000000000014178.

10.

Role of the HIF-1α/Nur77 axis in the regulation of the tyrosine hydroxylase expression by insulin in PC12 cells.

Fiory F, Mirra P, Nigro C, Pignalosa FC, Zatterale F, Ulianich L, Prevete N, Formisano P, Beguinot F, Miele C.

J Cell Physiol. 2019 Jul;234(7):11861-11870. doi: 10.1002/jcp.27898. Epub 2018 Dec 7.

PMID:
30536670
11.

Methylglyoxal accumulation de-regulates HoxA5 expression, thereby impairing angiogenesis in glyoxalase 1 knock-down mouse aortic endothelial cells.

Nigro C, Leone A, Longo M, Prevenzano I, Fleming TH, Nicolò A, Parrillo L, Spinelli R, Formisano P, Nawroth PP, Beguinot F, Miele C.

Biochim Biophys Acta Mol Basis Dis. 2019 Jan;1865(1):73-85. doi: 10.1016/j.bbadis.2018.10.014. Epub 2018 Oct 18.

PMID:
30342159
12.

The co-activator-associated arginine methyltransferase 1 (CARM1) gene is overexpressed in type 2 diabetes.

Porta M, Amione C, Barutta F, Fornengo P, Merlo S, Gruden G, Albano L, Ciccarelli M, Ungaro P, Durazzo M, Beguinot F, Berchialla P, Cavallo F, Trento M.

Endocrine. 2019 Feb;63(2):284-292. doi: 10.1007/s12020-018-1740-z. Epub 2018 Sep 1.

PMID:
30173329
13.

Prep1, A Homeodomain Transcription Factor Involved in Glucose and Lipid Metabolism.

Oriente F, Perruolo G, Cimmino I, Cabaro S, Liotti A, Longo M, Miele C, Formisano P, Beguinot F.

Front Endocrinol (Lausanne). 2018 Jun 28;9:346. doi: 10.3389/fendo.2018.00346. eCollection 2018. Review.

14.

High-fat diet unveils an enhancer element at the Ped/Pea-15 gene responsible for epigenetic memory in skeletal muscle.

Vastolo V, Nettore IC, Ciccarelli M, Albano L, Raciti GA, Longo M, Beguinot F, Ungaro P.

Metabolism. 2018 Oct;87:70-79. doi: 10.1016/j.metabol.2018.06.001. Epub 2018 Jun 19.

PMID:
29928894
15.

Oleic acid promotes prostate cancer malignant phenotype via the G protein-coupled receptor FFA1/GPR40.

Liotti A, Cosimato V, Mirra P, Calì G, Conza D, Secondo A, Luongo G, Terracciano D, Formisano P, Beguinot F, Insabato L, Ulianich L.

J Cell Physiol. 2018 Sep;233(9):7367-7378. doi: 10.1002/jcp.26572. Epub 2018 Apr 16.

PMID:
29663374
16.

Citrus aurantium L. dry extracts promote C/ebpβ expression and improve adipocyte differentiation in 3T3-L1 cells.

Raciti GA, Fiory F, Campitelli M, Desiderio A, Spinelli R, Longo M, Nigro C, Pepe G, Sommella E, Campiglia P, Formisano P, Beguinot F, Miele C.

PLoS One. 2018 Mar 29;13(3):e0193704. doi: 10.1371/journal.pone.0193704. eCollection 2018.

17.

The Destiny of Glucose from a MicroRNA Perspective.

Mirra P, Nigro C, Prevenzano I, Leone A, Raciti GA, Formisano P, Beguinot F, Miele C.

Front Endocrinol (Lausanne). 2018 Feb 26;9:46. doi: 10.3389/fendo.2018.00046. eCollection 2018. Review.

18.

Prep1 deficiency improves metabolic response in white adipose tissue.

Liotti A, Cabaro S, Cimmino I, Ricci S, Procaccini C, Paciello O, Raciti GA, Spinelli R, Iossa S, Matarese G, Miele C, Formisano P, Beguinot F, Oriente F.

Biochim Biophys Acta Mol Cell Biol Lipids. 2018 May;1863(5):515-525. doi: 10.1016/j.bbalip.2018.02.005. Epub 2018 Feb 21.

PMID:
29474930
19.

miR-214-Dependent Increase of PHLPP2 Levels Mediates the Impairment of Insulin-Stimulated Akt Activation in Mouse Aortic Endothelial Cells Exposed to Methylglyoxal.

Nigro C, Mirra P, Prevenzano I, Leone A, Fiory F, Longo M, Cabaro S, Oriente F, Beguinot F, Miele C.

Int J Mol Sci. 2018 Feb 9;19(2). pii: E522. doi: 10.3390/ijms19020522.

20.

Prep1 Deficiency Affects Olfactory Perception and Feeding Behavior by Impairing BDNF-TrkB Mediated Neurotrophic Signaling.

Ricci S, Viggiano D, Cimmino I, Perruolo G, Cabaro S, Liotti A, Fiory F, Spinelli R, Di Carlo A, Beguinot F, Formisano P, Oriente F.

Mol Neurobiol. 2018 Aug;55(8):6801-6815. doi: 10.1007/s12035-018-0873-7. Epub 2018 Jan 18.

21.

Glucose impairs tamoxifen responsiveness modulating connective tissue growth factor in breast cancer cells.

Ambrosio MR, D'Esposito V, Costa V, Liguoro D, Collina F, Cantile M, Prevete N, Passaro C, Mosca G, De Laurentiis M, Di Bonito M, Botti G, Franco R, Beguinot F, Ciccodicola A, Formisano P.

Oncotarget. 2017 Nov 20;8(65):109000-109017. doi: 10.18632/oncotarget.22552. eCollection 2017 Dec 12.

22.

Expression of Concern. Protein Kinase C (PKC)-α Activation Inhibits PKC-ζ and Mediates the Action of PED/PEA-15 on Glucose Transport in the L6 Skeletal Muscle Cells. Diabetes 2001;50:1244-1252. DOI: https://doi.org/10.2337/diabetes.50.6.1244. PMID: 11375323.

Condorelli G, Vigliotta G, Trencia A, Maitan MA, Caruso M, Miele C, Oriente F, Santopietro S, Formisano P, Beguinot F.

Diabetes. 2017 Nov 6. pii: db17ec2017b. doi: 10.2337/db17-ec2017b. [Epub ahead of print] No abstract available.

23.

Expression of Concern. Prep1 Controls Insulin Glucoregulatory Function in Liver by Transcriptional Targeting of SHP1 Tyrosine Phosphatase. Diabetes 2011;60:138-147. DOI: 10.2337/db10-0860. PMID: 20864515.

Oriente F, Iovino S, Cabaro S, Cassese A, Longobardi E, Miele C, Ungaro P, Formisano P, Blasi F, Beguinot F.

Diabetes. 2018 Feb;67(2):346-347. doi: 10.2337/db17-ec2017c. Epub 2017 Nov 6. No abstract available.

24.

Expression of Concern. The IR1152 Mutant Insulin Receptor Selectively Impairs Insulin Action in Skeletal Muscle but Not in Liver. Diabetes 2000;49:1194-1202. DOI: https://doi.org/10.2337/diabetes.49.7.1194. PMID: 10909978.

Caruso M, Miele C, Oliva A, Condorelli G, Oriente F, Riccardi G, Capaldo B, Fiory F, Accili D, Formisano P, Beguinot F.

Diabetes. 2017 Nov 6. pii: db17ec2017a. doi: 10.2337/db17-ec2017a. [Epub ahead of print] No abstract available.

25.

Phosphoprotein enriched in diabetes (PED/PEA15) promotes migration in hepatocellular carcinoma and confers resistance to sorafenib.

Quintavalle C, Hindupur SK, Quagliata L, Pallante P, Nigro C, Condorelli G, Andersen JB, Tagscherer KE, Roth W, Beguinot F, Heim MH, Ng CKY, Piscuoglio S, Matter MS.

Cell Death Dis. 2017 Oct 26;8(10):e3138. doi: 10.1038/cddis.2017.512.

26.

A peptide antagonist of Prep1-p160 interaction improves ceramide-induced insulin resistance in skeletal muscle cells.

Cimmino I, Lorenzo V, Fiory F, Doti N, Ricci S, Cabaro S, Liotti A, Vitagliano L, Longo M, Miele C, Formisano P, Beguinot F, Ruvo M, Oriente F.

Oncotarget. 2017 May 30;8(42):71845-71858. doi: 10.18632/oncotarget.18286. eCollection 2017 Sep 22.

27.

Epigenetic modifications of the Zfp/ZNF423 gene control murine adipogenic commitment and are dysregulated in human hypertrophic obesity.

Longo M, Raciti GA, Zatterale F, Parrillo L, Desiderio A, Spinelli R, Hammarstedt A, Hedjazifar S, Hoffmann JM, Nigro C, Mirra P, Fiory F, Formisano P, Miele C, Smith U, Beguinot F.

Diabetologia. 2018 Feb;61(2):369-380. doi: 10.1007/s00125-017-4471-4. Epub 2017 Oct 24.

28.

White cell and platelet content affects the release of bioactive factors in different blood-derived scaffolds.

Cabaro S, D'Esposito V, Gasparro R, Borriello F, Granata F, Mosca G, Passaretti F, Sammartino JC, Beguinot F, Sammartino G, Formisano P, Riccitiello F.

Platelets. 2018 Jul;29(5):463-467. doi: 10.1080/09537104.2017.1319046. Epub 2017 Jun 21.

PMID:
28635382
29.

Targetting PED/PEA-15 for diabetes treatment.

Fiory F, Spinelli R, Raciti GA, Parrillo L, D'esposito V, Formisano P, Miele C, Beguinot F.

Expert Opin Ther Targets. 2017 Jun;21(6):571-581. doi: 10.1080/14728222.2017.1317749. Epub 2017 Apr 21. Review.

PMID:
28395542
30.

Specific CpG hyper-methylation leads to Ankrd26 gene down-regulation in white adipose tissue of a mouse model of diet-induced obesity.

Raciti GA, Spinelli R, Desiderio A, Longo M, Parrillo L, Nigro C, D'Esposito V, Mirra P, Fiory F, Pilone V, Forestieri P, Formisano P, Pastan I, Miele C, Beguinot F.

Sci Rep. 2017 Mar 7;7:43526. doi: 10.1038/srep43526.

31.

The SGK1 inhibitor SI113 induces autophagy, apoptosis, and endoplasmic reticulum stress in endometrial cancer cells.

Conza D, Mirra P, Calì G, Tortora T, Insabato L, Fiory F, Schenone S, Amato R, Beguinot F, Perrotti N, Ulianich L.

J Cell Physiol. 2017 Dec;232(12):3735-3743. doi: 10.1002/jcp.25850. Epub 2017 Apr 27.

PMID:
28177128
32.

Methylglyoxal-Glyoxalase 1 Balance: The Root of Vascular Damage.

Nigro C, Leone A, Raciti GA, Longo M, Mirra P, Formisano P, Beguinot F, Miele C.

Int J Mol Sci. 2017 Jan 18;18(1). pii: E188. doi: 10.3390/ijms18010188. Review.

33.

The role of miR-190a in methylglyoxal-induced insulin resistance in endothelial cells.

Mirra P, Nigro C, Prevenzano I, Procopio T, Leone A, Raciti GA, Andreozzi F, Longo M, Fiory F, Beguinot F, Miele C.

Biochim Biophys Acta Mol Basis Dis. 2017 Feb;1863(2):440-449. doi: 10.1016/j.bbadis.2016.11.018. Epub 2016 Nov 15.

34.

Retraction: ER stress is associated with dedifferentiation and an epithelial-to-mesenchymal transition-like phenotype in PC Cl3 thyroid cells.

Ulianich L, Garbi C, Treglia AS, Punzi D, Miele C, Raciti GA, Beguinot F, Consiglio E, Di Jeso B.

J Cell Sci. 2016 Sep 15;129(18):3518. doi: 10.1242/jcs.196584. No abstract available.

35.

Human Peripheral Blood Mononuclear Cell Function and Dendritic Cell Differentiation Are Affected by Bisphenol-A Exposure.

Camarca A, Gianfrani C, Ariemma F, Cimmino I, Bruzzese D, Scerbo R, Picascia S, D'Esposito V, Beguinot F, Formisano P, Valentino R.

PLoS One. 2016 Aug 10;11(8):e0161122. doi: 10.1371/journal.pone.0161122. eCollection 2016.

36.

The GLP-1 receptor agonists exenatide and liraglutide activate Glucose transport by an AMPK-dependent mechanism.

Andreozzi F, Raciti GA, Nigro C, Mannino GC, Procopio T, Davalli AM, Beguinot F, Sesti G, Miele C, Folli F.

J Transl Med. 2016 Jul 30;14(1):229. doi: 10.1186/s12967-016-0985-7.

37.

Parkinson-like phenotype in insulin-resistant PED/PEA-15 transgenic mice.

Perruolo G, Viggiano D, Fiory F, Cassese A, Nigro C, Liotti A, Miele C, Beguinot F, Formisano P.

Sci Rep. 2016 Jul 18;6:29967. doi: 10.1038/srep29967.

38.

Epigenetics: spotlight on type 2 diabetes and obesity.

Desiderio A, Spinelli R, Ciccarelli M, Nigro C, Miele C, Beguinot F, Raciti GA.

J Endocrinol Invest. 2016 Oct;39(10):1095-103. doi: 10.1007/s40618-016-0473-1. Epub 2016 May 14. Review.

PMID:
27180180
39.

Adipose microenvironment promotes triple negative breast cancer cell invasiveness and dissemination by producing CCL5.

D'Esposito V, Liguoro D, Ambrosio MR, Collina F, Cantile M, Spinelli R, Raciti GA, Miele C, Valentino R, Campiglia P, De Laurentiis M, Di Bonito M, Botti G, Franco R, Beguinot F, Formisano P.

Oncotarget. 2016 Apr 26;7(17):24495-509. doi: 10.18632/oncotarget.8336.

40.

Hoxa5 undergoes dynamic DNA methylation and transcriptional repression in the adipose tissue of mice exposed to high-fat diet.

Parrillo L, Costa V, Raciti GA, Longo M, Spinelli R, Esposito R, Nigro C, Vastolo V, Desiderio A, Zatterale F, Ciccodicola A, Formisano P, Miele C, Beguinot F.

Int J Obes (Lond). 2016 Jun;40(6):929-37. doi: 10.1038/ijo.2016.36. Epub 2016 Mar 16.

PMID:
26980478
41.

Low-Dose Bisphenol-A Impairs Adipogenesis and Generates Dysfunctional 3T3-L1 Adipocytes.

Ariemma F, D'Esposito V, Liguoro D, Oriente F, Cabaro S, Liotti A, Cimmino I, Longo M, Beguinot F, Formisano P, Valentino R.

PLoS One. 2016 Mar 4;11(3):e0150762. doi: 10.1371/journal.pone.0150762. eCollection 2016.

42.

Pathologic endoplasmic reticulum stress induced by glucotoxic insults inhibits adipocyte differentiation and induces an inflammatory phenotype.

Longo M, Spinelli R, D'Esposito V, Zatterale F, Fiory F, Nigro C, Raciti GA, Miele C, Formisano P, Beguinot F, Di Jeso B.

Biochim Biophys Acta. 2016 Jun;1863(6 Pt A):1146-56. doi: 10.1016/j.bbamcr.2016.02.019. Epub 2016 Mar 2.

43.

Glucose-induced expression of the homeotic transcription factor Prep1 is associated with histone post-translational modifications in skeletal muscle.

Ciccarelli M, Vastolo V, Albano L, Lecce M, Cabaro S, Liotti A, Longo M, Oriente F, Russo GL, Macchia PE, Formisano P, Beguinot F, Ungaro P.

Diabetologia. 2016 Jan;59(1):176-186. doi: 10.1007/s00125-015-3774-6. Epub 2015 Oct 9.

PMID:
26453063
44.

Dissecting metabolic syndrome components: data from an epidemiologic survey in a genetic isolate.

Biino G, Concas MP, Cena H, Parracciani D, Vaccargiu S, Cosso M, Marras F, D'Esposito V, Beguinot F, Pirastu M.

Springerplus. 2015 Jul 7;4:324. doi: 10.1186/s40064-015-1049-9. eCollection 2015.

45.

Circulating miRNAs as intercellular messengers, potential biomarkers and therapeutic targets for Type 2 diabetes.

Mirra P, Raciti GA, Nigro C, Fiory F, D'Esposito V, Formisano P, Beguinot F, Miele C.

Epigenomics. 2015;7(4):653-67. doi: 10.2217/epi.15.18. Review.

PMID:
26111035
46.

Bisphenol A environmental exposure and the detrimental effects on human metabolic health: is it necessary to revise the risk assessment in vulnerable population?

Valentino R, D'Esposito V, Ariemma F, Cimmino I, Beguinot F, Formisano P.

J Endocrinol Invest. 2016 Mar;39(3):259-63. doi: 10.1007/s40618-015-0336-1. Epub 2015 Jun 24. Review.

47.

Bisphenol-A plasma levels are related to inflammatory markers, visceral obesity and insulin-resistance: a cross-sectional study on adult male population.

Savastano S, Tarantino G, D'Esposito V, Passaretti F, Cabaro S, Liotti A, Liguoro D, Perruolo G, Ariemma F, Finelli C, Beguinot F, Formisano P, Valentino R.

J Transl Med. 2015 May 29;13:169. doi: 10.1186/s12967-015-0532-y.

48.

Platelet-Rich Plasma Increases Growth and Motility of Adipose Tissue-Derived Mesenchymal Stem Cells and Controls Adipocyte Secretory Function.

D'Esposito V, Passaretti F, Perruolo G, Ambrosio MR, Valentino R, Oriente F, Raciti GA, Nigro C, Miele C, Sammartino G, Beguinot F, Formisano P.

J Cell Biochem. 2015 Oct;116(10):2408-18. doi: 10.1002/jcb.25235.

49.

Regulatory T cells, inflammation, and endoplasmic reticulum stress in women with defective endometrial receptivity.

Galgani M, Insabato L, Calì G, Della Gatta AN, Mirra P, Papaccio F, Santopaolo M, Alviggi C, Mollo A, Strina I, Matarese G, Beguinot F, De Placido G, Ulianich L.

Fertil Steril. 2015 Jun;103(6):1579-86.e1. doi: 10.1016/j.fertnstert.2015.03.014. Epub 2015 Apr 29.

PMID:
25935494
50.

Understanding type 2 diabetes: from genetics to epigenetics.

Raciti GA, Longo M, Parrillo L, Ciccarelli M, Mirra P, Ungaro P, Formisano P, Miele C, Béguinot F.

Acta Diabetol. 2015 Oct;52(5):821-7. doi: 10.1007/s00592-015-0741-0. Epub 2015 Apr 5. Review.

PMID:
25841587

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