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Exploring bacterial resistome and resistance dessemination: an approach of whole genome sequencing.

Beg AZ, Khan AU.

Future Med Chem. 2019 Feb 25. doi: 10.4155/fmc-2018-0201. [Epub ahead of print]


Development and validation of HPLC method for the determination of Candesartan in human plasma.

Hamid S, Beg AE, Muhammad IN, Hassan S, Hassan A, Akram A, Alladin N.

Pak J Pharm Sci. 2018 Nov;31(6):2323-2327.


A new health care professional-based model for medication adherence.

Amir M, Feroz Z, Beg AE.

Patient Prefer Adherence. 2018 Oct 10;12:2085-2091. doi: 10.2147/PPA.S171989. eCollection 2018.


High throughput screening, docking, and molecular dynamics studies to identify potential inhibitors of human calcium/calmodulin-dependent protein kinase IV.

Beg A, Khan FI, Lobb KA, Islam A, Ahmad F, Hassan MI.

J Biomol Struct Dyn. 2019 May;37(8):2179-2192. doi: 10.1080/07391102.2018.1479310. Epub 2018 Nov 1.


Assessment of Frequency and Transience Rate for Ventilator-Associated Pneumonia (VAP) in Geriatric Patients in Tertiary Care Settings of Karachi, Pakistan.

Zubair S, Ali H, Raza SF, Warind JA, Beg AE, Bushra R.

J Coll Physicians Surg Pak. 2018 Jul;28(7):536-540. doi: 10.29271/jcpsp.2018.07.536.


Genome analyses of blaNDM-4 carrying ST 315 Escherichia coli isolate from sewage water of one of the Indian hospitals.

Beg AZ, Khan AU.

Gut Pathog. 2018 May 24;10:17. doi: 10.1186/s13099-018-0247-8. eCollection 2018.


Dual phosphorylation of Ric-8A enhances its ability to mediate G protein α subunit folding and to stimulate guanine nucleotide exchange.

Papasergi-Scott MM, Stoveken HM, MacConnachie L, Chan PY, Gabay M, Wong D, Freeman RS, Beg AA, Tall GG.

Sci Signal. 2018 May 29;11(532). pii: eaap8113. doi: 10.1126/scisignal.aap8113.


A Rapid and Facile Pipeline for Generating Genomic Point Mutants in C. elegans Using CRISPR/Cas9 Ribonucleoproteins.

Prior H, MacConnachie L, Martinez JL, Nicholl GCB, Beg AA.

J Vis Exp. 2018 Apr 30;(134). doi: 10.3791/57518.


Drug utilization and prescribing pattern of antibiotics in a tertiary care setups; trends and practices.

Ali H, Zafar F, Alam S, Beg AE, Bushra R, Manzoor A, Naqvi GR, Yasmeen R, Shafiq Y, Tariq A, Zubair S, Saleem S.

Pak J Pharm Sci. 2018 Mar;31(2(Suppl.)):691-697.


Incidence of drug interactions in intensive care units in tertiary care settings: Classification, facts and measures.

Hasnain H, Ali H, Zafar F, Sial AA, Alam S, Beg AE, Bushra R, Rizvi M, Khan MA, Shareef H, Naqvi GR, Tariq A.

Pak J Pharm Sci. 2018 Mar;31(2(Suppl.)):669-675.


Effects of superdisintegrants in oral dissolving formulation of cinitapride tablets.

Rehman A, Bushra R, Beg AE, Ali H, Zafar F, Ashfaq M, Alam S, Mustapha O, Shafique S.

Pak J Pharm Sci. 2018 Mar;31(2(Suppl.)):643-650.


Draft Genome Sequence of the First NDM-4-Producing Escherichia coli Strain (AK1), Isolated from Sewage Water of a North Indian Hospital.

Khan AU, Beg AZ, Verma PK.

Genome Announc. 2017 Dec 14;5(50). pii: e01366-17. doi: 10.1128/genomeA.01366-17.


Development and validation of stability indicating assay method for cinitapride in bulk & tablets.

Rehman A, Beg AE, Bushra R, Ashfaq M, Zafar F, Ali H, Rizvi M.

Pak J Pharm Sci. 2017 Nov;30(6(Supplementary)):2341-2347.


Highly Efficient, Rapid and Co-CRISPR-Independent Genome Editing in Caenorhabditis elegans.

Prior H, Jawad AK, MacConnachie L, Beg AA.

G3 (Bethesda). 2017 Nov 6;7(11):3693-3698. doi: 10.1534/g3.117.300216.


Ascorbic acid inhibits human insulin aggregation and protects against amyloid induced cytotoxicity.

Alam P, Beg AZ, Siddiqi MK, Chaturvedi SK, Rajpoot RK, Ajmal MR, Zaman M, Abdelhameed AS, Khan RH.

Arch Biochem Biophys. 2017 May 1;621:54-62. doi: 10.1016/ Epub 2017 Apr 12.


Pharmacological characterization of the excitatory 'Cys-loop' GABA receptor family in Caenorhabditis elegans.

Nicholl GC, Jawad AK, Weymouth R, Zhang H, Beg AA.

Br J Pharmacol. 2017 May;174(9):781-795. doi: 10.1111/bph.13736. Epub 2017 Mar 10.


Predicting the pathogenicity of aminoacyl-tRNA synthetase mutations.

Oprescu SN, Griffin LB, Beg AA, Antonellis A.

Methods. 2017 Jan 15;113:139-151. doi: 10.1016/j.ymeth.2016.11.013. Epub 2016 Nov 20. Review.


Comparison of effectiveness and cost of patent ductus arteriosus device occlusion versus surgical ligation of patent ductus arteriosus.

Zulqarnain A, Younas M, Waqar T, Beg A, Asma T, Baig MA.

Pak J Med Sci. 2016 Jul-Aug;32(4):974-7. doi: 10.12669/pjms.324.10048.


HDAC inhibitors with PD-1 blockade: a promising strategy for treatment of multiple cancer types?

Beg AA, Gray JE.

Epigenomics. 2016 Aug;8(8):1015-7. doi: 10.2217/epi-2016-0066. Epub 2016 Jul 13. No abstract available.


The Rac-GAP alpha2-chimaerin regulates hippocampal dendrite and spine morphogenesis.

Valdez CM, Murphy GG, Beg AA.

Mol Cell Neurosci. 2016 Sep;75:14-26. doi: 10.1016/j.mcn.2016.06.002. Epub 2016 Jun 11.


Correlation between Umbilical Cord Diameter and Cross Sectional Area with Gestational Age and Foetal Anthropometric Parameters.

Begum K, Ahmed MU, Rahman MM, Hossain MM, Begum M, Sarkar SK, Reza MT, Hoshneara M, Beg A, Sultana F, Begum F, Akter FA.

Mymensingh Med J. 2016 Apr;25(2):190-7.


HDAC Inhibitors Enhance T-Cell Chemokine Expression and Augment Response to PD-1 Immunotherapy in Lung Adenocarcinoma.

Zheng H, Zhao W, Yan C, Watson CC, Massengill M, Xie M, Massengill C, Noyes DR, Martinez GV, Afzal R, Chen Z, Ren X, Antonia SJ, Haura EB, Ruffell B, Beg AA.

Clin Cancer Res. 2016 Aug 15;22(16):4119-32. doi: 10.1158/1078-0432.CCR-15-2584. Epub 2016 Mar 10.


A Sensitive NanoString-Based Assay to Score STK11 (LKB1) Pathway Disruption in Lung Adenocarcinoma.

Chen L, Engel BE, Welsh EA, Yoder SJ, Brantley SG, Chen DT, Beg AA, Cao C, Kaye FJ, Haura EB, Schabath MB, Cress WD.

J Thorac Oncol. 2016 Jun;11(6):838-49. doi: 10.1016/j.jtho.2016.02.009. Epub 2016 Feb 23.


Propelling Immunotherapy Combinations Into the Clinic.

Tchekmedyian N, Gray JE, Creelan BC, Chiappori AA, Beg AA, Soliman H, Perez BA, Antonia SJ.

Oncology (Williston Park). 2015 Dec;29(12):990-1002. Review.


Differential association of STK11 and TP53 with KRAS mutation-associated gene expression, proliferation and immune surveillance in lung adenocarcinoma.

Schabath MB, Welsh EA, Fulp WJ, Chen L, Teer JK, Thompson ZJ, Engel BE, Xie M, Berglund AE, Creelan BC, Antonia SJ, Gray JE, Eschrich SA, Chen DT, Cress WD, Haura EB, Beg AA.

Oncogene. 2016 Jun 16;35(24):3209-16. doi: 10.1038/onc.2015.375. Epub 2015 Oct 19.


Obstetric Outcome in Early and Late Onset Gestational Diabetes Mellitus.

Easmin S, Chowdhury TA, Islam MR, Beg A, Jahan MK, Latif T, Dhar S, Alam MN, Akhter M.

Mymensingh Med J. 2015 Jul;24(3):450-6.


Charting Immune Signaling Proteomes En Route to New Therapeutic Strategies.

Haura EB, Beg AA, Rix U, Antonia S.

Cancer Immunol Res. 2015 Jul;3(7):714-20. doi: 10.1158/2326-6066.CIR-15-0094. Epub 2015 Jun 16. Review.


Loss of function mutations in HARS cause a spectrum of inherited peripheral neuropathies.

Safka Brozkova D, Deconinck T, Griffin LB, Ferbert A, Haberlova J, Mazanec R, Lassuthova P, Roth C, Pilunthanakul T, Rautenstrauss B, Janecke AR, Zavadakova P, Chrast R, Rivolta C, Zuchner S, Antonellis A, Beg AA, De Jonghe P, Senderek J, Seeman P, Baets J.

Brain. 2015 Aug;138(Pt 8):2161-72. doi: 10.1093/brain/awv158. Epub 2015 Jun 13.


Comorbidities with Posttraumatic Stress Disorder (PTSD) among combat veterans: 15 years postwar analysis.

Britvić D, Antičević V, Kaliterna M, Lušić L, Beg A, Brajević-Gizdić I, Kudrić M, Stupalo Ž, Krolo V, Pivac N.

Int J Clin Health Psychol. 2015 May-Aug;15(2):81-92. doi: 10.1016/j.ijchp.2014.11.002. Epub 2014 Dec 25.


Spillover transmission is mediated by the excitatory GABA receptor LGC-35 in C. elegans.

Jobson MA, Valdez CM, Gardner J, Garcia LR, Jorgensen EM, Beg AA.

J Neurosci. 2015 Feb 11;35(6):2803-16. doi: 10.1523/JNEUROSCI.4557-14.2015.


α2-chimaerin is required for Eph receptor-class-specific spinal motor axon guidance and coordinate activation of antagonistic muscles.

Kao TJ, Nicholl GC, Johansen JA, Kania A, Beg AA.

J Neurosci. 2015 Feb 11;35(6):2344-57. doi: 10.1523/JNEUROSCI.4151-14.2015.


Interleukin polymorphisms associated with overall survival, disease-free survival, and recurrence in non-small cell lung cancer patients.

Woods NT, Monteiro AN, Thompson ZJ, Amankwah EK, Naas N, Haura EB, Beg AA, Schabath MB.

Mol Carcinog. 2015 Jun;54 Suppl 1:E172-84. doi: 10.1002/mc.22275. Epub 2015 Jan 18.


NF-κB is crucial in proximal T-cell signaling for calcium influx and NFAT activation.

Bronk CC, Yoder S, Hopewell EL, Yang S, Celis E, Yu XZ, Beg AA.

Eur J Immunol. 2014 Dec;44(12):3741-6. doi: 10.1002/eji.201444904. Epub 2014 Oct 22.


Differential requirement for the IKKβ/NF-κB signaling module in regulating TLR- versus RLR-induced type 1 IFN expression in dendritic cells.

Wang X, Wang J, Zheng H, Xie M, Hopewell EL, Albrecht RA, Nogusa S, García-Sastre A, Balachandran S, Beg AA.

J Immunol. 2014 Sep 1;193(5):2538-45. doi: 10.4049/jimmunol.1400675. Epub 2014 Jul 23.


An N-terminal threonine mutation produces an efflux-favorable, sodium-primed conformation of the human dopamine transporter.

Fraser R, Chen Y, Guptaroy B, Luderman KD, Stokes SL, Beg A, DeFelice LJ, Gnegy ME.

Mol Pharmacol. 2014 Jul;86(1):76-85. doi: 10.1124/mol.114.091926. Epub 2014 Apr 21.


A new role for NFκB in immunosurveillance and its implications for cancer immunotherapy.

Beg AA, Khan T, Antonia SJ.

Oncoimmunology. 2013 Oct 1;2(10):e25963. Epub 2013 Aug 2.


Association of air pollution on birth outcomes in New Delhi - a pilot study on the potential of HMIS data for environmental public health tracking.

Magsumbol MS, Singh A, Ghosh A, Kler N, Garg P, Thakur A, Beg A, Srivastava A, Hajat S.

Indian J Med Inform. 2014;8(2):52-56.


Non-canonical IKKs, IKKϵ and TBK1, as novel therapeutic targets in the treatment of non-small cell lung cancer.

Kim JY, Beg AA, Haura EB.

Expert Opin Ther Targets. 2013 Oct;17(10):1109-12. doi: 10.1517/14728222.2013.833188. Epub 2013 Aug 28.


Pharmacologic inhibition of PKCα and PKCθ prevents GVHD while preserving GVL activity in mice.

Haarberg KM, Li J, Heinrichs J, Wang D, Liu C, Bronk CC, Kaosaard K, Owyang AM, Holland S, Masuda E, Tso K, Blazar BR, Anasetti C, Beg AA, Yu XZ.

Blood. 2013 Oct 3;122(14):2500-11. doi: 10.1182/blood-2012-12-471938. Epub 2013 Aug 1.


TNFRSF10B polymorphisms and haplotypes associated with increased risk of death in non-small cell lung cancer.

Schabath MB, Giuliano AR, Thompson ZJ, Amankwah EK, Gray JE, Fenstermacher DA, Jonathan KA, Beg AA, Haura EB.

Carcinogenesis. 2013 Nov;34(11):2525-30. doi: 10.1093/carcin/bgt244. Epub 2013 Jul 9.


Dissection of TBK1 signaling via phosphoproteomics in lung cancer cells.

Kim JY, Welsh EA, Oguz U, Fang B, Bai Y, Kinose F, Bronk C, Remsing Rix LL, Beg AA, Rix U, Eschrich SA, Koomen JM, Haura EB.

Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12414-9. doi: 10.1073/pnas.1220674110. Epub 2013 Jul 8.


c-Rel is an essential transcription factor for the development of acute graft-versus-host disease in mice.

Yu Y, Wang D, Kaosaard K, Liu C, Fu J, Haarberg K, Anasetti C, Beg AA, Yu XZ.

Eur J Immunol. 2013 Sep;43(9):2327-37. doi: 10.1002/eji.201243282. Epub 2013 Jul 4.


Lung tumor NF-κB signaling promotes T cell-mediated immune surveillance.

Hopewell EL, Zhao W, Fulp WJ, Bronk CC, Lopez AS, Massengill M, Antonia S, Celis E, Haura EB, Enkemann SA, Chen DT, Beg AA.

J Clin Invest. 2013 Jun;123(6):2509-22. doi: 10.1172/JCI67250. Epub 2013 May 1.


Efficacy of microwaves and chlorhexidine for disinfection of pacifiers and toothbrushes: an in vitro study.

Chamele J, Bhat C, Saraf T, Jadhav A, Beg A, Jagtap C, Ubeja R, Patil P.

J Contemp Dent Pract. 2012 Sep 1;13(5):690-4.


Analysis of ochratoxin A blood levels in bladder cancer cases and healthy persons from Pakistan.

Aslam M, Rivzi SA, Beg AE, Blaszkewicz M, Golka K, Degen GH.

J Toxicol Environ Health A. 2012;75(19-20):1176-84.


A loss-of-function variant in the human histidyl-tRNA synthetase (HARS) gene is neurotoxic in vivo.

Vester A, Velez-Ruiz G, McLaughlin HM; NISC Comparative Sequencing Program, Lupski JR, Talbot K, Vance JM, Züchner S, Roda RH, Fischbeck KH, Biesecker LG, Nicholson G, Beg AA, Antonellis A.

Hum Mutat. 2013 Jan;34(1):191-9. doi: 10.1002/humu.22210. Epub 2012 Oct 11.


Upregulation and inhibition of the nuclear translocation of Oct4 during multistep gastric carcinogenesis.

Al-Marzoqee FY, Khoder G, Al-Awadhi H, John R, Beg A, Vincze A, Branicki F, Karam SM.

Int J Oncol. 2012 Nov;41(5):1733-43. doi: 10.3892/ijo.2012.1608. Epub 2012 Aug 24.


Targeting PKCθ in alloreactivity and graft-versus-host-disease: unanswered questions and therapeutic potential.

Bronk CC, Yu XZ, Beg AA.

Front Immunol. 2012 Aug 14;3:259. doi: 10.3389/fimmu.2012.00259. eCollection 2012.


Phosphoregulation of STIM1 leads to exclusion of the endoplasmic reticulum from the mitotic spindle.

Smyth JT, Beg AM, Wu S, Putney JW Jr, Rusan NM.

Curr Biol. 2012 Aug 21;22(16):1487-93. doi: 10.1016/j.cub.2012.05.057. Epub 2012 Jun 28.


IKBKE is induced by STAT3 and tobacco carcinogen and determines chemosensitivity in non-small cell lung cancer.

Guo J, Kim D, Gao J, Kurtyka C, Chen H, Yu C, Wu D, Mittal A, Beg AA, Chellappan SP, Haura EB, Cheng JQ.

Oncogene. 2013 Jan 10;32(2):151-9. doi: 10.1038/onc.2012.39. Epub 2012 Feb 13.

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