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Items: 1 to 50 of 207

1.

Strengthening routine immunization in Papua New Guinea: a cross-sectional provincial assessment of front-line services.

Morgan CJ, Saweri OPM, Larme N, Peach E, Melepia P, Au L, Scoullar MJL, Reza MS, Vallely LM, McPake BI, Beeson JG.

BMC Public Health. 2020 Jan 23;20(1):100. doi: 10.1186/s12889-020-8172-4.

2.

IgM in human immunity to Plasmodium falciparum malaria.

Boyle MJ, Chan JA, Handayuni I, Reiling L, Feng G, Hilton A, Kurtovic L, Oyong D, Piera KA, Barber BE, William T, Eisen DP, Minigo G, Langer C, Drew DR, de Labastida Rivera F, Amante FH, Williams TN, Kinyanjui S, Marsh K, Doolan DL, Engwerda C, Fowkes FJI, Grigg MJ, Mueller I, McCarthy JS, Anstey NM, Beeson JG.

Sci Adv. 2019 Sep 25;5(9):eaax4489. doi: 10.1126/sciadv.aax4489. eCollection 2019 Sep.

3.

Complement in malaria immunity and vaccines.

Kurtovic L, Boyle MJ, Opi DH, Kennedy AT, Tham WH, Reiling L, Chan JA, Beeson JG.

Immunol Rev. 2020 Jan;293(1):38-56. doi: 10.1111/imr.12802. Epub 2019 Sep 26. Review.

PMID:
31556468
4.

Malaria vaccine candidates displayed on novel virus-like particles are immunogenic and induce transmission-blocking activity.

Chan JA, Wetzel D, Reiling L, Miura K, Drew DR, Gilson PR, Anderson DA, Richards JS, Long CA, Suckow M, Jenzelewski V, Tsuboi T, Boyle MJ, Piontek M, Beeson JG.

PLoS One. 2019 Sep 10;14(9):e0221733. doi: 10.1371/journal.pone.0221733. eCollection 2019.

5.

Display of malaria transmission-blocking antigens on chimeric duck hepatitis B virus-derived virus-like particles produced in Hansenula polymorpha.

Wetzel D, Chan JA, Suckow M, Barbian A, Weniger M, Jenzelewski V, Reiling L, Richards JS, Anderson DA, Kouskousis B, Palmer C, Hanssen E, Schembecker G, Merz J, Beeson JG, Piontek M.

PLoS One. 2019 Sep 4;14(9):e0221394. doi: 10.1371/journal.pone.0221394. eCollection 2019.

6.

Induction and Kinetics of Complement-Fixing Antibodies Against Plasmodium vivax Merozoite Surface Protein 3α and Relationship With Immunoglobulin G Subclasses and Immunoglobulin M.

Oyong DA, Wilson DW, Barber BE, William T, Jiang J, Galinski MR, Fowkes FJI, Grigg MJ, Beeson JG, Anstey NM, Boyle MJ.

J Infect Dis. 2019 Nov 6;220(12):1950-1961. doi: 10.1093/infdis/jiz407.

PMID:
31419296
7.

RTS,S/AS01E immunization increases antibody responses to vaccine-unrelated Plasmodium falciparum antigens associated with protection against clinical malaria in African children: a case-control study.

Dobaño C, Ubillos I, Jairoce C, Gyan B, Vidal M, Jiménez A, Santano R, Dosoo D, Nhabomba AJ, Ayestaran A, Aguilar R, Williams NA, Díez-Padrisa N, Lanar D, Chauhan V, Chitnis C, Dutta S, Gaur D, Angov E, Asante KP, Owusu-Agyei S, Valim C, Gamain B, Coppel RL, Cavanagh D, Beeson JG, Campo JJ, Moncunill G.

BMC Med. 2019 Aug 14;17(1):157. doi: 10.1186/s12916-019-1378-6.

8.
9.

Antibody Reactivity to Merozoite Antigens in Ghanaian Adults Correlates With Growth Inhibitory Activity Against Plasmodium falciparum in Culture.

Mensah-Brown HE, Aspeling-Jones H, Delimini RK, Asante KP, Amlabu E, Bah SY, Beeson JG, Wright GJ, Conway DJ, Awandare GA.

Open Forum Infect Dis. 2019 May 28;6(7):ofz254. doi: 10.1093/ofid/ofz254. eCollection 2019 Jul.

10.

Contribution of Functional Antimalarial Immunity to Measures of Parasite Clearance in Therapeutic Efficacy Studies of Artemisinin Derivatives.

O'Flaherty K, Ataíde R, Zaloumis SG, Ashley EA, Powell R, Feng G, Reiling L, Dondorp AM, Day NP, Dhorda M, Fairhurst RM, Lim P, Amaratunga C, Pukrittayakamee S, Hien TT, Htut Y, Mayxay M, Faiz MA, Beeson JG, Nosten F, Simpson JA, White NJ, Fowkes FJI.

J Infect Dis. 2019 Aug 30;220(7):1178-1187. doi: 10.1093/infdis/jiz247.

11.

Differential Patterns of IgG Subclass Responses to Plasmodium falciparum Antigens in Relation to Malaria Protection and RTS,S Vaccination.

Dobaño C, Santano R, Vidal M, Jiménez A, Jairoce C, Ubillos I, Dosoo D, Aguilar R, Williams NA, Díez-Padrisa N, Ayestaran A, Valim C, Asante KP, Owusu-Agyei S, Lanar D, Chauhan V, Chitnis C, Dutta S, Angov E, Gamain B, Coppel RL, Beeson JG, Reiling L, Gaur D, Cavanagh D, Gyan B, Nhabomba AJ, Campo JJ, Moncunill G.

Front Immunol. 2019 Mar 15;10:439. doi: 10.3389/fimmu.2019.00439. eCollection 2019.

12.

Dendritic Cell Responses and Function in Malaria.

Yap XZ, Lundie RJ, Beeson JG, O'Keeffe M.

Front Immunol. 2019 Mar 4;10:357. doi: 10.3389/fimmu.2019.00357. eCollection 2019. Review.

13.

Induction and decay of functional complement-fixing antibodies by the RTS,S malaria vaccine in children, and a negative impact of malaria exposure.

Kurtovic L, Agius PA, Feng G, Drew DR, Ubillos I, Sacarlal J, Aponte JJ, Fowkes FJI, Dobaño C, Beeson JG.

BMC Med. 2019 Feb 25;17(1):45. doi: 10.1186/s12916-019-1277-x.

14.

Sulphadoxine-pyrimethamine plus azithromycin may improve birth outcomes through impacts on inflammation and placental angiogenesis independent of malarial infection.

Unger HW, Hansa AP, Buffet C, Hasang W, Teo A, Randall L, Ome-Kaius M, Karl S, Anuan AA, Beeson JG, Mueller I, Stock SJ, Rogerson SJ.

Sci Rep. 2019 Feb 19;9(1):2260. doi: 10.1038/s41598-019-38821-2.

15.

Hepatitis B virus-like particles expressing Plasmodium falciparum epitopes induce complement-fixing antibodies against the circumsporozoite protein.

Kingston NJ, Kurtovic L, Walsh R, Joe C, Lovrecz G, Locarnini S, Beeson JG, Netter HJ.

Vaccine. 2019 Mar 14;37(12):1674-1684. doi: 10.1016/j.vaccine.2019.01.056. Epub 2019 Feb 14.

PMID:
30773400
16.

Different Life Cycle Stages of Plasmodium falciparum Induce Contrasting Responses in Dendritic Cells.

Yap XZ, Lundie RJ, Feng G, Pooley J, Beeson JG, O'Keeffe M.

Front Immunol. 2019 Jan 31;10:32. doi: 10.3389/fimmu.2019.00032. eCollection 2019.

17.

Targeting malaria parasite invasion of red blood cells as an antimalarial strategy.

Burns AL, Dans MG, Balbin JM, de Koning-Ward TF, Gilson PR, Beeson JG, Boyle MJ, Wilson DW.

FEMS Microbiol Rev. 2019 May 1;43(3):223-238. doi: 10.1093/femsre/fuz005. Review.

18.

Targets of complement-fixing antibodies in protective immunity against malaria in children.

Reiling L, Boyle MJ, White MT, Wilson DW, Feng G, Weaver R, Opi DH, Persson KEM, Richards JS, Siba PM, Fowkes FJI, Takashima E, Tsuboi T, Mueller I, Beeson JG.

Nat Commun. 2019 Feb 5;10(1):610. doi: 10.1038/s41467-019-08528-z.

19.

Antibody Responses to Antigenic Targets of Recent Exposure Are Associated With Low-Density Parasitemia in Controlled Human Plasmodium falciparum Infections.

van den Hoogen LL, Walk J, Oulton T, Reuling IJ, Reiling L, Beeson JG, Coppel RL, Singh SK, Draper SJ, Bousema T, Drakeley C, Sauerwein R, Tetteh KKA.

Front Microbiol. 2019 Jan 16;9:3300. doi: 10.3389/fmicb.2018.03300. eCollection 2018.

20.

Low Levels of Human Antibodies to Gametocyte-Infected Erythrocytes Contrasts the PfEMP1-Dominant Response to Asexual Stages in P. falciparum Malaria.

Chan JA, Drew DR, Reiling L, Lisboa-Pinto A, Dinko B, Sutherland CJ, Dent AE, Chelimo K, Kazura JW, Boyle MJ, Beeson JG.

Front Immunol. 2019 Jan 14;9:3126. doi: 10.3389/fimmu.2018.03126. eCollection 2018.

21.

The impact of early life exposure to Plasmodium falciparum on the development of naturally acquired immunity to malaria in young Malawian children.

Barua P, Beeson JG, Maleta K, Ashorn P, Rogerson SJ.

Malar J. 2019 Jan 18;18(1):11. doi: 10.1186/s12936-019-2647-8.

22.

Challenges and strategies for developing efficacious and long-lasting malaria vaccines.

Beeson JG, Kurtovic L, Dobaño C, Opi DH, Chan JA, Feng G, Good MF, Reiling L, Boyle MJ.

Sci Transl Med. 2019 Jan 9;11(474). pii: eaau1458. doi: 10.1126/scitranslmed.aau1458. Review.

PMID:
30626712
23.

KILchip v1.0: A Novel Plasmodium falciparum Merozoite Protein Microarray to Facilitate Malaria Vaccine Candidate Prioritization.

Kamuyu G, Tuju J, Kimathi R, Mwai K, Mburu J, Kibinge N, Chong Kwan M, Hawkings S, Yaa R, Chepsat E, Njunge JM, Chege T, Guleid F, Rosenkranz M, Kariuki CK, Frank R, Kinyanjui SM, Murungi LM, Bejon P, Färnert A, Tetteh KKA, Beeson JG, Conway DJ, Marsh K, Rayner JC, Osier FHA.

Front Immunol. 2018 Dec 11;9:2866. doi: 10.3389/fimmu.2018.02866. eCollection 2018.

24.

Effectiveness of repellent delivered through village health volunteers on malaria incidence in villages in South-East Myanmar: a stepped-wedge cluster-randomised controlled trial protocol.

Win Han Oo, Cutts JC, Agius PA, Kyaw Zayar Aung, Poe Poe Aung, Aung Thi, Nyi Nyi Zaw, Htin Kyaw Thu, Wai Yan Min Htay, Ataide R, O'Flaherty K, Ai Pao Yawn, Aung Paing Soe, Beeson JG, Crabb B, Pasricha N, Fowkes FJI.

BMC Infect Dis. 2018 Dec 14;18(1):663. doi: 10.1186/s12879-018-3566-y.

25.

Loss of complement regulatory proteins on uninfected erythrocytes in vivax and falciparum malaria anemia.

Oyong DA, Kenangalem E, Poespoprodjo JR, Beeson JG, Anstey NM, Price RN, Boyle MJ.

JCI Insight. 2018 Nov 15;3(22). pii: 124854. doi: 10.1172/jci.insight.124854.

26.

Antibody Targets on the Surface of Plasmodium falciparum-Infected Erythrocytes That Are Associated With Immunity to Severe Malaria in Young Children.

Chan JA, Boyle MJ, Moore KA, Reiling L, Lin Z, Hasang W, Avril M, Manning L, Mueller I, Laman M, Davis T, Smith JD, Rogerson SJ, Simpson JA, Fowkes FJI, Beeson JG.

J Infect Dis. 2019 Feb 15;219(5):819-828. doi: 10.1093/infdis/jiy580.

PMID:
30365004
27.

Acquisition of Antibodies Against Endothelial Protein C Receptor-Binding Domains of Plasmodium falciparum Erythrocyte Membrane Protein 1 in Children with Severe Malaria.

Rambhatla JS, Turner L, Manning L, Laman M, Davis TME, Beeson JG, Mueller I, Warrel J, Theander TG, Lavstsen T, Rogerson SJ.

J Infect Dis. 2019 Feb 15;219(5):808-818. doi: 10.1093/infdis/jiy564.

PMID:
30365003
28.

Multiple morbidities in pregnancy: Time for research, innovation, and action.

Beeson JG, Homer CSE, Morgan C, Menendez C.

PLoS Med. 2018 Sep 25;15(9):e1002665. doi: 10.1371/journal.pmed.1002665. eCollection 2018 Sep.

29.

Iron deficiency during pregnancy is associated with a reduced risk of adverse birth outcomes in a malaria-endemic area in a longitudinal cohort study.

Fowkes FJI, Moore KA, Opi DH, Simpson JA, Langham F, Stanisic DI, Ura A, King CL, Siba PM, Mueller I, Rogerson SJ, Beeson JG.

BMC Med. 2018 Sep 20;16(1):156. doi: 10.1186/s12916-018-1146-z.

30.

Cellular dissection of malaria parasite invasion of human erythrocytes using viable Plasmodium knowlesi merozoites.

Lyth O, Vizcay-Barrena G, Wright KE, Haase S, Mohring F, Najer A, Henshall IG, Ashdown GW, Bannister LH, Drew DR, Beeson JG, Fleck RA, Moon RW, Wilson DW, Baum J.

Sci Rep. 2018 Jul 5;8(1):10165. doi: 10.1038/s41598-018-28457-z.

31.

Factors influencing the induction of high affinity antibodies to Plasmodium falciparum merozoite antigens and how affinity changes over time.

Tijani MK, Reddy SB, Langer C, Beeson JG, Wahlgren M, Nwuba RI, Persson KEM.

Sci Rep. 2018 Jun 13;8(1):9026. doi: 10.1038/s41598-018-27361-w.

32.

The Complement System Contributes to Functional Antibody-Mediated Responses Induced by Immunization with Plasmodium falciparum Malaria Sporozoites.

Behet MC, Kurtovic L, van Gemert GJ, Haukes CM, Siebelink-Stoter R, Graumans W, van de Vegte-Bolmer MG, Scholzen A, Langereis JD, Diavatopoulos DA, Beeson JG, Sauerwein RW.

Infect Immun. 2018 Jun 21;86(7). pii: e00920-17. doi: 10.1128/IAI.00920-17. Print 2018 Jul.

33.

Human antibodies activate complement against Plasmodium falciparum sporozoites, and are associated with protection against malaria in children.

Kurtovic L, Behet MC, Feng G, Reiling L, Chelimo K, Dent AE, Mueller I, Kazura JW, Sauerwein RW, Fowkes FJI, Beeson JG.

BMC Med. 2018 Apr 30;16(1):61. doi: 10.1186/s12916-018-1054-2.

34.

Human Immunization With a Polymorphic Malaria Vaccine Candidate Induced Antibodies to Conserved Epitopes That Promote Functional Antibodies to Multiple Parasite Strains.

Feng G, Boyle MJ, Cross N, Chan JA, Reiling L, Osier F, Stanisic DI, Mueller I, Anders RF, McCarthy JS, Richards JS, Beeson JG.

J Infect Dis. 2018 Jun 5;218(1):35-43. doi: 10.1093/infdis/jiy170.

35.

Proteome-wide mapping of immune features onto Plasmodium protein three-dimensional structures.

Guy AJ, Irani V, Beeson JG, Webb B, Sali A, Richards JS, Ramsland PA.

Sci Rep. 2018 Mar 12;8(1):4355. doi: 10.1038/s41598-018-22592-3.

36.

Combating low birth weight due to malaria infection in pregnancy.

Beeson JG, Scoullar MJL, Boeuf P.

Sci Transl Med. 2018 Mar 7;10(431). pii: eaat1506. doi: 10.1126/scitranslmed.aat1506. Review.

PMID:
29514997
37.

Effect of nutrient supplementation on the acquisition of humoral immunity to Plasmodium falciparum in young Malawian children.

Barua P, Chandrasiri UP, Beeson JG, Dewey KG, Maleta K, Ashorn P, Rogerson SJ.

Malar J. 2018 Feb 7;17(1):74. doi: 10.1186/s12936-018-2224-6.

38.

Establishment of a yeast-based VLP platform for antigen presentation.

Wetzel D, Rolf T, Suckow M, Kranz A, Barbian A, Chan JA, Leitsch J, Weniger M, Jenzelewski V, Kouskousis B, Palmer C, Beeson JG, Schembecker G, Merz J, Piontek M.

Microb Cell Fact. 2018 Feb 5;17(1):17. doi: 10.1186/s12934-018-0868-0.

39.

Identifying Immune Correlates of Protection Against Plasmodium falciparum Through a Novel Approach to Account for Heterogeneity in Malaria Exposure.

Valmaseda A, Macete E, Nhabomba A, Guinovart C, Aide P, Bardají A, Bassat Q, Nhampossa T, Maculuve S, Casellas A, Quintó L, Sanz S, Jiménez A, Feng G, Langer C, Reiling L, Reddy KS, Pandey A, Chitnis CE, Chauhan VS, Aguilar R, Aponte JJ, Dobaño C, Beeson JG, Gaur D, Menéndez C, Alonso PL, Mayor A.

Clin Infect Dis. 2018 Feb 1;66(4):586-593. doi: 10.1093/cid/cix837.

PMID:
29401272
40.

Evaluating antibody functional activity and strain-specificity of vaccine candidates for malaria in pregnancy using in vitro phagocytosis assays.

Hommel M, Chan JA, Umbers AJ, Langer C, Rogerson SJ, Smith JD, Beeson JG.

Parasit Vectors. 2018 Jan 29;11(1):69. doi: 10.1186/s13071-018-2653-7.

41.

The potential of task shifting selected maternal interventions to auxiliary midwives in Myanmar: a mixed-method study.

Than KK, Tin KN, La T, Thant KS, Myint T, Beeson JG, Luchters S, Morgan A.

BMC Public Health. 2018 Jan 3;18(1):99. doi: 10.1186/s12889-017-5020-2.

42.

Functional Conservation of the AMA1 Host-Cell Invasion Ligand Between P. falciparum and P. vivax: A Novel Platform to Accelerate Vaccine and Drug Development.

Drew DR, Sanders PR, Weiss G, Gilson PR, Crabb BS, Beeson JG.

J Infect Dis. 2018 Jan 17;217(3):498-507. doi: 10.1093/infdis/jix583.

PMID:
29165651
43.

Impaired placental autophagy in placental malaria.

Dimasuay KG, Gong L, Rosario F, McBryde E, Spelman T, Glazier J, Rogerson SJ, Beeson JG, Jansson T, Devenish RJ, Boeuf P.

PLoS One. 2017 Nov 10;12(11):e0187291. doi: 10.1371/journal.pone.0187291. eCollection 2017.

44.

P. falciparum infection and maternofetal antibody transfer in malaria-endemic settings of varying transmission.

McLean ARD, Stanisic D, McGready R, Chotivanich K, Clapham C, Baiwog F, Pimanpanarak M, Siba P, Mueller I, King CL, Nosten F, Beeson JG, Rogerson S, Simpson JA, Fowkes FJI.

PLoS One. 2017 Oct 13;12(10):e0186577. doi: 10.1371/journal.pone.0186577. eCollection 2017.

45.

Declining Malaria Transmission Differentially Impacts the Maintenance of Humoral Immunity to Plasmodium falciparum in Children.

Mugyenyi CK, Elliott SR, Yap XZ, Feng G, Boeuf P, Fegan G, Osier FFH, Fowkes FJI, Avril M, Williams TN, Marsh K, Beeson JG.

J Infect Dis. 2017 Oct 17;216(7):887-898. doi: 10.1093/infdis/jix370.

46.

Declining Transmission and Immunity to Malaria and Emerging Artemisinin Resistance in Thailand: A Longitudinal Study.

Ataíde R, Powell R, Moore K, McLean A, Phyo AP, Nair S, White M, Anderson TJ, Beeson JG, Simpson JA, Nosten F, Fowkes FJI.

J Infect Dis. 2017 Sep 15;216(6):723-731. doi: 10.1093/infdis/jix371.

47.

Identification of Heparin Modifications and Polysaccharide Inhibitors of Plasmodium falciparum Merozoite Invasion That Have Potential for Novel Drug Development.

Boyle MJ, Skidmore M, Dickerman B, Cooper L, Devlin A, Yates E, Horrocks P, Freeman C, Chai W, Beeson JG.

Antimicrob Agents Chemother. 2017 Oct 24;61(11). pii: e00709-17. doi: 10.1128/AAC.00709-17. Print 2017 Nov.

48.

Patterns of protective associations differ for antibodies to P. falciparum-infected erythrocytes and merozoites in immunity against malaria in children.

Chan JA, Stanisic DI, Duffy MF, Robinson LJ, Lin E, Kazura JW, King CL, Siba PM, Fowkes FJ, Mueller I, Beeson JG.

Eur J Immunol. 2017 Dec;47(12):2124-2136. doi: 10.1002/eji.201747032. Epub 2017 Sep 13.

49.

Acquisition, maintenance and adaptation of invasion inhibitory antibodies against Plasmodium falciparum invasion ligands involved in immune evasion.

Tijani MK, Babalola OA, Odaibo AB, Anumudu CI, Asinobi AO, Morenikeji OA, Asuzu MC, Langer C, Reiling L, Beeson JG, Wahlgren M, Nwuba RI, Persson KEM.

PLoS One. 2017 Aug 7;12(8):e0182187. doi: 10.1371/journal.pone.0182187. eCollection 2017.

50.

Dichotomous miR expression and immune responses following primary blood-stage malaria.

Burel JG, Apte SH, Groves PL, Boyle MJ, Langer C, Beeson JG, McCarthy JS, Doolan DL.

JCI Insight. 2017 Aug 3;2(15). pii: 93434. doi: 10.1172/jci.insight.93434. eCollection 2017 Aug 3.

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