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Items: 23


Renal Glomerular Mitochondria Function in Salt-Sensitive Hypertension.

Domondon M, Polina I, Nikiforova AB, Sultanova RF, Kruger C, Vasileva VY, Fomin MV, Beeson GC, Nieminen AL, Smythe N, Maldonado EN, Stadler K, Ilatovskaya DV.

Front Physiol. 2020 Feb 4;10:1588. doi: 10.3389/fphys.2019.01588. eCollection 2019.


Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity.

Chakraborty P, Vaena SG, Thyagarajan K, Chatterjee S, Al-Khami A, Selvam SP, Nguyen H, Kang I, Wyatt MW, Baliga U, Hedley Z, Ngang RN, Guo B, Beeson GC, Husain S, Paulos CM, Beeson CC, Zilliox MJ, Hill EG, Mehrotra M, Yu XZ, Ogretmen B, Mehrotra S.

Cell Rep. 2019 Aug 13;28(7):1879-1893.e7. doi: 10.1016/j.celrep.2019.07.044.


An improved method for isolation of mitochondria from cell lines that enables reconstitution of calcium-dependent processes.

Ishii M, Beeson G, Beeson C, Rohrer B.

Anal Biochem. 2019 Jul 15;577:52-58. doi: 10.1016/j.ab.2019.04.012. Epub 2019 Apr 22.


Statin-dependent modulation of mitochondrial metabolism in cancer cells is independent of cholesterol content.

Christie CF, Fang D, Hunt EG, Morris ME, Rovini A, Heslop KA, Beeson GC, Beeson CC, Maldonado EN.

FASEB J. 2019 Jul;33(7):8186-8201. doi: 10.1096/fj.201802723R. Epub 2019 Apr 5.


Targeting glutamine-addiction and overcoming CDK4/6 inhibitor resistance in human esophageal squamous cell carcinoma.

Qie S, Yoshida A, Parnham S, Oleinik N, Beeson GC, Beeson CC, Ogretmen B, Bass AJ, Wong KK, Rustgi AK, Diehl JA.

Nat Commun. 2019 Mar 21;10(1):1296. doi: 10.1038/s41467-019-09179-w.


A Screen Using iPSC-Derived Hepatocytes Reveals NAD+ as a Potential Treatment for mtDNA Depletion Syndrome.

Jing R, Corbett JL, Cai J, Beeson GC, Beeson CC, Chan SS, Dimmock DP, Lazcares L, Geurts AM, Lemasters JJ, Duncan SA.

Cell Rep. 2018 Nov 6;25(6):1469-1484.e5. doi: 10.1016/j.celrep.2018.10.036.


Getting accountability right.

Cox S, Beeson G.

Nurs Manage. 2018 Sep;49(9):24-30. doi: 10.1097/01.NUMA.0000544458.73828.42. Review. No abstract available.


CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response.

Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt MW, Dhar P, Selvam SP, Fu J, Zhang J, Nguyen H, Kang I, Toth K, Al-Homrani M, Husain M, Beeson G, Ball L, Helke K, Husain S, Garrett-Mayer E, Hardiman G, Mehrotra M, Nishimura MI, Beeson CC, Bupp MG, Wu J, Ogretmen B, Paulos CM, Rathmell J, Yu XZ, Mehrotra S.

Cell Metab. 2018 Jan 9;27(1):85-100.e8. doi: 10.1016/j.cmet.2017.10.006. Epub 2017 Nov 9.


Transforming growth factor β1 (TGFβ1) regulates CD44V6 expression and activity through extracellular signal-regulated kinase (ERK)-induced EGR1 in pulmonary fibrogenic fibroblasts.

Ghatak S, Markwald RR, Hascall VC, Dowling W, Lottes RG, Baatz JE, Beeson G, Beeson CC, Perrella MA, Thannickal VJ, Misra S.

J Biol Chem. 2017 Jun 23;292(25):10465-10489. doi: 10.1074/jbc.M116.752451. Epub 2017 Apr 7.


Increased expression of estrogen-related receptor β during adaptation of adult cardiomyocytes to sustained hypoxia.

Cunningham KF, Beeson GC, Beeson CC, McDermott PJ.

Am J Cardiovasc Dis. 2016 May 18;6(2):46-54. eCollection 2016.


Enhancing NAD+ Salvage Pathway Reverts the Toxicity of Primary Astrocytes Expressing Amyotrophic Lateral Sclerosis-linked Mutant Superoxide Dismutase 1 (SOD1).

Harlan BA, Pehar M, Sharma DR, Beeson G, Beeson CC, Vargas MR.

J Biol Chem. 2016 May 13;291(20):10836-46. doi: 10.1074/jbc.M115.698779. Epub 2016 Mar 21.


Assessment of ToxCast Phase II for Mitochondrial Liabilities Using a High-Throughput Respirometric Assay.

Wills LP, Beeson GC, Hoover DB, Schnellmann RG, Beeson CC.

Toxicol Sci. 2015 Aug;146(2):226-34. doi: 10.1093/toxsci/kfv085. Epub 2015 Apr 28.


Estrogen-Related Receptor α (ERRα) is required for adaptive increases in PGC-1 isoform expression during electrically stimulated contraction of adult cardiomyocytes in sustained hypoxic conditions.

Cunningham KF, Beeson GC, Beeson CC, Baicu CF, Zile MR, McDermott PJ.

Int J Cardiol. 2015;187:393-400. doi: 10.1016/j.ijcard.2015.03.353. Epub 2015 Mar 25.


Promoting thiol expression increases the durability of antitumor T-cell functions.

Kesarwani P, Al-Khami AA, Scurti G, Thyagarajan K, Kaur N, Husain S, Fang Q, Naga OS, Simms P, Beeson G, Voelkel-Johnson C, Garrett-Mayer E, Beeson CC, Nishimura MI, Mehrotra S.

Cancer Res. 2014 Nov 1;74(21):6036-6047. doi: 10.1158/0008-5472.CAN-14-1084. Epub 2014 Aug 27.


Mitochondria-targeted catalase reverts the neurotoxicity of hSOD1G⁹³A astrocytes without extending the survival of ALS-linked mutant hSOD1 mice.

Pehar M, Beeson G, Beeson CC, Johnson JA, Vargas MR.

PLoS One. 2014 Jul 23;9(7):e103438. doi: 10.1371/journal.pone.0103438. eCollection 2014.


Systematic study of mitochondrial toxicity of environmental chemicals using quantitative high throughput screening.

Attene-Ramos MS, Huang R, Sakamuru S, Witt KL, Beeson GC, Shou L, Schnellmann RG, Beeson CC, Tice RR, Austin CP, Xia M.

Chem Res Toxicol. 2013 Sep 16;26(9):1323-32. doi: 10.1021/tx4001754. Epub 2013 Aug 15.


High-throughput respirometric assay identifies predictive toxicophore of mitochondrial injury.

Wills LP, Beeson GC, Trager RE, Lindsey CC, Beeson CC, Peterson YK, Schnellmann RG.

Toxicol Appl Pharmacol. 2013 Oct 15;272(2):490-502. doi: 10.1016/j.taap.2013.06.014. Epub 2013 Jun 26.


LCL124, a cationic analog of ceramide, selectively induces pancreatic cancer cell death by accumulating in mitochondria.

Beckham TH, Lu P, Jones EE, Marrison T, Lewis CS, Cheng JC, Ramshesh VK, Beeson G, Beeson CC, Drake RR, Bielawska A, Bielawski J, Szulc ZM, Ogretmen B, Norris JS, Liu X.

J Pharmacol Exp Ther. 2013 Jan;344(1):167-78. doi: 10.1124/jpet.112.199216. Epub 2012 Oct 18.


Assessment of drug-induced mitochondrial dysfunction via altered cellular respiration and acidification measured in a 96-well platform.

Nadanaciva S, Rana P, Beeson GC, Chen D, Ferrick DA, Beeson CC, Will Y.

J Bioenerg Biomembr. 2012 Aug;44(4):421-37. doi: 10.1007/s10863-012-9446-z. Epub 2012 Jun 12.


The β2-adrenoceptor agonist formoterol stimulates mitochondrial biogenesis.

Wills LP, Trager RE, Beeson GC, Lindsey CC, Peterson YK, Beeson CC, Schnellmann RG.

J Pharmacol Exp Ther. 2012 Jul;342(1):106-18. doi: 10.1124/jpet.112.191528. Epub 2012 Apr 6.


Integrin-dependent Akt1 activation regulates PGC-1 expression and fatty acid oxidation.

Beeson CC, Beeson GC, Buff H, Eldridge J, Zhang A, Seth A, Demcheva M, Vournakis JN, Muise-Helmericks RC.

J Vasc Res. 2012;49(2):89-100. doi: 10.1159/000332326. Epub 2012 Jan 13.


A high-throughput respirometric assay for mitochondrial biogenesis and toxicity.

Beeson CC, Beeson GC, Schnellmann RG.

Anal Biochem. 2010 Sep 1;404(1):75-81. doi: 10.1016/j.ab.2010.04.040. Epub 2010 May 11.


Chromosome numbers of slugs.


Nature. 1960 Apr 16;186:257-8. No abstract available.


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