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Recruitment of Older Veterans with Diabetes Risk for Alzheimer's Disease for a Randomized Clinical Trial of Computerized Cognitive Training.

Karran M, Guerrero-Berroa E, Schmeidler J, Lee PG, Alexander N, Nabozny M, West RK, Beeri MS, Sano M, Silverman JM.

J Alzheimers Dis. 2019;69(2):401-411. doi: 10.3233/JAD-180952.


Short-term computerized cognitive training does not improve cognition compared to an active control in non-demented adults aged 80 years and above.

West RK, Rabin LA, Silverman JM, Moshier E, Sano M, Beeri MS.

Int Psychogeriatr. 2019 Apr 10:1-9. doi: 10.1017/S1041610219000267. [Epub ahead of print]


Computerized cognitive training for older adults at higher dementia risk due to diabetes: findings from a randomized controlled trial.

Bahar-Fuchs A, Barendse MEA, Bloom R, Ravona-Springer R, Heymann A, Dabush H, Bar L, Slater S, Rassovsky Y, Beeri MS.

J Gerontol A Biol Sci Med Sci. 2019 Mar 14. pii: glz073. doi: 10.1093/gerona/glz073. [Epub ahead of print]


Association of metformin, sulfonylurea and insulin use with brain structure and function and risk of dementia and Alzheimer's disease: Pooled analysis from 5 cohorts.

Weinstein G, Davis-Plourde KL, Conner S, Himali JJ, Beiser AS, Lee A, Rawlings AM, Sedaghat S, Ding J, Moshier E, van Duijn CM, Beeri MS, Selvin E, Ikram MA, Launer LJ, Haan MN, Seshadri S.

PLoS One. 2019 Feb 15;14(2):e0212293. doi: 10.1371/journal.pone.0212293. eCollection 2019.


Distinct age-related associations for body mass index and cognition in cognitively healthy very old veterans.

Schmeidler J, Mastrogiacomo CN, Beeri MS, Rosendorff C, Silverman JM.

Int Psychogeriatr. 2019 Jun;31(6):895-899. doi: 10.1017/S1041610218001412. Epub 2019 Feb 5.


The associations between objective and subjective health among older adults with type 2 diabetes: The moderating role of personality.

Elran-Barak R, Weinstein G, Beeri MS, Ravona-Springer R.

J Psychosom Res. 2019 Feb;117:41-47. doi: 10.1016/j.jpsychores.2018.12.011. Epub 2018 Dec 26.


Association of the Haptoglobin Gene Polymorphism With Cognitive Function and Decline in Elderly African American Adults With Type 2 Diabetes: Findings From the Action to Control Cardiovascular Risk in Diabetes-Memory in Diabetes (ACCORD-MIND) Study.

Beeri MS, Lin HM, Sano M, Ravona-Springer R, Liu X, Bendlin BB, Gleason CE, Guerrero-Berroa E, Soleimani L, Launer LJ, Ehrenberg S, Lache O, Seligman YK, Levy AP.

JAMA Netw Open. 2018 Nov 2;1(7):e184458. doi: 10.1001/jamanetworkopen.2018.4458.


Combination of Insulin with a GLP1 Agonist Is Associated with Better Memory and Normal Expression of Insulin Receptor Pathway Genes in a Mouse Model of Alzheimer's Disease.

Robinson A, Lubitz I, Atrakchi-Baranes D, Licht-Murava A, Katsel P, Leroith D, Liraz-Zaltsman S, Haroutunian V, Beeri MS.

J Mol Neurosci. 2019 Apr;67(4):504-510. doi: 10.1007/s12031-019-1257-9. Epub 2019 Jan 11.


Depression is more strongly associated with cognition in elderly women than men with type 2 diabetes.

Soleimani L, Ravona-Springer R, Heymann A, Guerrero-Berroa E, Schmeidler J, Zukran R, Preiss R, Silverman JM, Sano M, Beeri MS.

Int Psychogeriatr. 2018 Dec 11:1-5. doi: 10.1017/S104161021800114X. [Epub ahead of print]


Blood-Brain Barrier Cellular Responses Toward Organophosphates: Natural Compensatory Processes and Exogenous Interventions to Rescue Barrier Properties.

Ravid O, Elhaik Goldman S, Macheto D, Bresler Y, De Oliveira RI, Liraz-Zaltsman S, Gosselet F, Dehouck L, Beeri MS, Cooper I.

Front Cell Neurosci. 2018 Oct 16;12:359. doi: 10.3389/fncel.2018.00359. eCollection 2018.


Parahippocampal gyrus expression of endothelial and insulin receptor signaling pathway genes is modulated by Alzheimer's disease and normalized by treatment with anti-diabetic agents.

Katsel P, Roussos P, Beeri MS, Gama-Sosa MA, Gandy S, Khan S, Haroutunian V.

PLoS One. 2018 Nov 1;13(11):e0206547. doi: 10.1371/journal.pone.0206547. eCollection 2018.


Traumatic brain injury associated with dementia risk among people with type 1 diabetes.

Gilsanz P, Albers K, Beeri MS, Karter AJ, Quesenberry CP Jr, Whitmer RA.

Neurology. 2018 Oct 23;91(17):e1611-e1618. doi: 10.1212/WNL.0000000000006391. Epub 2018 Sep 26.


Depressive Symptoms Are Associated with Cognitive Function in the Elderly with Type 2 Diabetes.

Guerrero-Berroa E, Ravona-Springer R, Schmeidler J, Heymann A, Soleimani L, Sano M, Leroith D, Preiss R, Zukran R, Silverman JM, Beeri MS.

J Alzheimers Dis. 2018;65(2):683-692. doi: 10.3233/JAD-170778.


The chicken or the egg? Does glycaemic control predict cognitive function or the other way around?

Ganmore I, Beeri MS.

Diabetologia. 2018 Sep;61(9):1913-1917. doi: 10.1007/s00125-018-4689-9. Epub 2018 Jul 12.


Virtual reality-based cognitive-motor training for middle-aged adults at high Alzheimer's disease risk: A randomized controlled trial.

Doniger GM, Beeri MS, Bahar-Fuchs A, Gottlieb A, Tkachov A, Kenan H, Livny A, Bahat Y, Sharon H, Ben-Gal O, Cohen M, Zeilig G, Plotnik M.

Alzheimers Dement (N Y). 2018 Mar 27;4:118-129. doi: 10.1016/j.trci.2018.02.005. eCollection 2018.


The association of total cholesterol with processing speed is moderated by age in mid- to late-age healthy adults.

Elkana O, Dayman V, Franko M, Israel A, Springer RR, Segev S, Beeri MS.

Exp Aging Res. 2018 Mar-Apr;44(2):179-186. doi: 10.1080/0361073X.2017.1422585. Epub 2018 Jan 5.


The Bidirectional Association Between Depression and Severe Hypoglycemic and Hyperglycemic Events in Type 1 Diabetes.

Gilsanz P, Karter AJ, Beeri MS, Quesenberry CP Jr, Whitmer RA.

Diabetes Care. 2018 Mar;41(3):446-452. doi: 10.2337/dc17-1566. Epub 2017 Dec 18.


Hemoglobin A1c Variability Predicts Symptoms of Depression in Elderly Individuals With Type 2 Diabetes.

Ravona-Springer R, Heymann A, Schmeidler J, Moshier E, Guerrero-Berroa E, Soleimani L, Sano M, Leroith D, Preiss R, Tzukran R, Silverman JM, Beeri MS.

Diabetes Care. 2017 Sep;40(9):1187-1193. doi: 10.2337/dc16-2754. Epub 2017 Jun 20.


Insulin resistance is associated with lower arterial blood flow and reduced cortical perfusion in cognitively asymptomatic middle-aged adults.

Hoscheidt SM, Kellawan JM, Berman SE, Rivera-Rivera LA, Krause RA, Oh JM, Beeri MS, Rowley HA, Wieben O, Carlsson CM, Asthana S, Johnson SC, Schrage WG, Bendlin BB.

J Cereb Blood Flow Metab. 2017 Jun;37(6):2249-2261. doi: 10.1177/0271678X16663214. Epub 2016 Jan 1.


Potential contribution of the Alzheimer's disease risk locus BIN1 to episodic memory performance in cognitively normal Type 2 diabetes elderly.

Greenbaum L, Ravona-Springer R, Lubitz I, Schmeidler J, Cooper I, Sano M, Silverman JM, Heymann A, Beeri MS.

Eur Neuropsychopharmacol. 2016 Apr;26(4):787-95. doi: 10.1016/j.euroneuro.2015.11.004. Epub 2015 Nov 14.


Neuropsychological Test Performance in Cognitively Normal Spanish-speaking Nonagenarians with Little Education.

Guerrero-Berroa E, Schmeidler J, Raventos H, Valerio D, Beeri MS, Carrión-Baralt JR, Mora-Villalobos L, Bolaños P, Sano M, Silverman JM.

J Cross Cult Gerontol. 2016 Jun;31(2):129-41. doi: 10.1007/s10823-016-9285-1.


Brain BDNF expression as a biomarker for cognitive reserve against Alzheimer disease progression.

Beeri MS, Sonnen J.

Neurology. 2016 Feb 23;86(8):702-3. doi: 10.1212/WNL.0000000000002389. Epub 2016 Jan 27. No abstract available.


Higher Fasting Plasma Glucose Levels, within the Normal Range, are Associated with Decreased Processing Speed in High Functioning Young Elderly.

Raizes M, Elkana O, Franko M, Ravona Springer R, Segev S, Beeri MS.

J Alzheimers Dis. 2016;49(3):589-92. doi: 10.3233/JAD-150433.


Statin Use is Associated with Better Cognitive Function in Elderly with Type 2 Diabetes.

Heymann AD, Ravona-Springer R, Moshier EL, Godbold J, Beeri MS.

J Alzheimers Dis. 2015;47(1):55-9. doi: 10.3233/JAD-142571.


Impaired Cerebral Hemodynamics and Cognitive Performance in Patients with Atherothrombotic Disease.

Haratz S, Weinstein G, Molshazki N, Beeri MS, Ravona-Springer R, Marzeliak O, Goldbourt U, Tanne D.

J Alzheimers Dis. 2015;46(1):137-44. doi: 10.3233/JAD-150052.


Haptoglobin genotype modulates the relationships of glycaemic control with cognitive function in elderly individuals with type 2 diabetes.

Guerrero-Berroa E, Ravona-Springer R, Heymann A, Schmeidler J, Levy A, Leroith D, Beeri MS.

Diabetologia. 2015 Apr;58(4):736-44. doi: 10.1007/s00125-014-3487-2. Epub 2015 Jan 28.


Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus.

Lunnon K, Smith RG, Cooper I, Greenbaum L, Mill J, Beeri MS.

Neurobiol Aging. 2015 Mar;36(3):1600.e1-4. doi: 10.1016/j.neurobiolaging.2014.12.023. Epub 2014 Dec 24.


Improvement of memory impairments in poststroke patients by hyperbaric oxygen therapy.

Boussi-Gross R, Golan H, Volkov O, Bechor Y, Hoofien D, Beeri MS, Ben-Jacob E, Efrati S.

Neuropsychology. 2015 Jul;29(4):610-21. doi: 10.1037/neu0000149. Epub 2014 Nov 10.


Shorter adult height is associated with poorer cognitive performance in elderly men with type II diabetes.

West RK, Ravona-Springer R, Heymann A, Schmeidler J, Leroith D, Koifman K, Guerrero-Berroa E, Preiss R, Hoffman H, Silverman JM, Beeri MS.

J Alzheimers Dis. 2015;44(3):927-35. doi: 10.3233/JAD-142049.


Arterial wall function is associated with cognitive performance primarily in elderly with type 2 diabetes.

Ravona-Springer R, Haratz S, Tanne D, Schmeidler J, Efrati S, Rosendorff C, Beeri MS, Silverman JM.

J Alzheimers Dis. 2015;44(2):687-93. doi: 10.3233/JAD-141197.


The Israel Diabetes and Cognitive Decline (IDCD) study: Design and baseline characteristics.

Beeri MS, Ravona-Springer R, Moshier E, Schmeidler J, Godbold J, Karpati T, Leroith D, Koifman K, Kravitz E, Price R, Hoffman H, Silverman JM, Heymann A.

Alzheimers Dement. 2014 Nov;10(6):769-78. doi: 10.1016/j.jalz.2014.06.002. Epub 2014 Aug 20.


The TOMM40 poly-T rs10524523 variant is associated with cognitive performance among non-demented elderly with type 2 diabetes.

Greenbaum L, Springer RR, Lutz MW, Heymann A, Lubitz I, Cooper I, Kravitz E, Sano M, Roses AD, Silverman JM, Saunders AM, Beeri MS.

Eur Neuropsychopharmacol. 2014 Sep;24(9):1492-9. doi: 10.1016/j.euroneuro.2014.06.002. Epub 2014 Jun 13.


Dietary advanced glycation end products are associated with decline in memory in young elderly.

West RK, Moshier E, Lubitz I, Schmeidler J, Godbold J, Cai W, Uribarri J, Vlassara H, Silverman JM, Beeri MS.

Mech Ageing Dev. 2014 Sep;140:10-2. doi: 10.1016/j.mad.2014.07.001. Epub 2014 Jul 15.


Trajectories in glycemic control over time are associated with cognitive performance in elderly subjects with type 2 diabetes.

Ravona-Springer R, Heymann A, Schmeidler J, Moshier E, Godbold J, Sano M, Leroith D, Johnson S, Preiss R, Koifman K, Hoffman H, Silverman JM, Beeri MS.

PLoS One. 2014 Jun 2;9(6):e97384. doi: 10.1371/journal.pone.0097384. eCollection 2014.


The ApoE4 genotype modifies the relationship of long-term glycemic control with cognitive functioning in elderly with type 2 diabetes.

Ravona-Springer R, Heymann A, Schmeidler J, Sano M, Preiss R, Koifman K, Hoffman H, Silverman JM, Beeri MS.

Eur Neuropsychopharmacol. 2014 Aug;24(8):1303-8. doi: 10.1016/j.euroneuro.2014.05.001. Epub 2014 May 14.


Association of apolipoprotein E-e4 and dementia declines with age.

Valerio D, Raventos H, Schmeidler J, Beeri MS, Villalobos LM, Bolaños-Palmieri P, Carrión-Baralt JR, Fornaguera J, Silverman JM.

Am J Geriatr Psychiatry. 2014 Oct;22(10):957-60. doi: 10.1016/j.jagp.2014.03.008. Epub 2014 Mar 21.


Neuropathology of type 2 diabetes: a short review on insulin-related mechanisms.

Guerrero-Berroa E, Schmeidler J, Beeri MS.

Eur Neuropsychopharmacol. 2014 Dec;24(12):1961-6. doi: 10.1016/j.euroneuro.2014.01.019. Epub 2014 Jan 30. Review.


Cognitive decline and dementia in the oldest-old.

Kravitz E, Schmeidler J, Beeri MS.

Rambam Maimonides Med J. 2012 Oct 31;3(4):e0026. doi: 10.5041/RMMJ.10092. Print 2012 Oct.


Epigenetic determinants of healthy and diseased brain aging and cognition.

Akbarian S, Beeri MS, Haroutunian V.

JAMA Neurol. 2013 Jun;70(6):711-8. doi: 10.1001/jamaneurol.2013.1459. Review.


C-reactive protein and familial risk for dementia: a phenotype for successful cognitive aging.

Silverman JM, Schmeidler J, Beeri MS, Rosendorff C, Sano M, Grossman HT, Carrión-Baralt JR, Bespalova IN, West R, Haroutunian V.

Neurology. 2012 Sep 11;79(11):1116-23. doi: 10.1212/WNL.0b013e3182698c89. Epub 2012 Aug 15.


Being physically active may protect the brain from Alzheimer disease.

Beeri MS, Middleton L.

Neurology. 2012 Apr 24;78(17):1290-1. doi: 10.1212/WNL.0b013e3182535f0e. Epub 2012 Apr 18. No abstract available.


Changes in glycemic control are associated with changes in cognition in non-diabetic elderly.

Ravona-Springer R, Moshier E, Schmeidler J, Godbold J, Akrivos J, Rapp M, Grossman HT, Wysocki M, Silverman JM, Haroutunian V, Beeri MS.

J Alzheimers Dis. 2012;30(2):299-309. doi: 10.3233/JAD-2012-120106.


Correlation of arterial blood pressure and compliance with left ventricular structure and function in the very elderly.

Rosendorff C, Go O, Schmeidler J, Silverman JM, Beeri MS.

J Am Soc Hypertens. 2012 Jan-Feb;6(1):48-55. doi: 10.1016/j.jash.2011.10.004.


Synaptic protein deficits are associated with dementia irrespective of extreme old age.

Beeri MS, Haroutunian V, Schmeidler J, Sano M, Fam P, Kavanaugh A, Barr AM, Honer WG, Katsel P.

Neurobiol Aging. 2012 Jun;33(6):1125.e1-8. doi: 10.1016/j.neurobiolaging.2011.08.017. Epub 2011 Dec 27.


Serum concentration of an inflammatory glycotoxin, methylglyoxal, is associated with increased cognitive decline in elderly individuals.

Beeri MS, Moshier E, Schmeidler J, Godbold J, Uribarri J, Reddy S, Sano M, Grossman HT, Cai W, Vlassara H, Silverman JM.

Mech Ageing Dev. 2011 Nov-Dec;132(11-12):583-7. doi: 10.1016/j.mad.2011.10.007. Epub 2011 Nov 3.


Haemoglobin A(1c) and cognitive function in very old, cognitively intact men.

Huang J, Schmeidler J, Beeri MS, Rosendorff C, Bhatia S, West RK, Bespalova IN, Mavris R, Silverman JM.

Age Ageing. 2012 Jan;41(1):125-8. doi: 10.1093/ageing/afr124. Epub 2011 Sep 18. No abstract available.


Heritability of cognitive functions in families of successful cognitive aging probands from the Central Valley of Costa Rica.

Greenwood TA, Beeri MS, Schmeidler J, Valerio D, Raventós H, Mora-Villalobos L, Camacho K, Carrión-Baralt JR, Angelo G, Almasy L, Sano M, Silverman JM.

J Alzheimers Dis. 2011;27(4):897-907. doi: 10.3233/JAD-2011-110782.


Fibrinogen and cognitive function in very old non-demented men.

Huang J, Schmeidler J, Beeri MS, West RK, Rosendorff C, Silverman JM.

Int J Geriatr Psychiatry. 2011 Oct;26(10):1099-100. doi: 10.1002/gps.2659. No abstract available.


Hypertension is associated with cognitive decline in elderly people at high risk for dementia.

Wysocki M, Luo X, Schmeidler J, Dahlman K, Lesser GT, Grossman H, Haroutunian V, Beeri MS.

Am J Geriatr Psychiatry. 2012 Feb;20(2):179-87. doi: 10.1097/JGP.0b013e31820ee833.

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