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Items: 1 to 50 of 215

1.

18F-FDG PET intensity correlates with a hypoxic gene signature and other oncogenic abnormalities in operable non-small cell lung cancer.

Heiden BT, Chen G, Hermann M, Brown RKJ, Orringer MB, Lin J, Chang AC, Carrott PW, Lynch WR, Zhao L, Beer DG, Reddy RM.

PLoS One. 2018 Jul 2;13(7):e0199970. doi: 10.1371/journal.pone.0199970. eCollection 2018.

2.

Induction of Thioredoxin-Interacting Protein by Histone Deacetylase Inhibitor, Entinostat, Is Associated with DNA Damage and Apoptosis in Esophageal Adenocarcinoma.

Feingold PL, Surman DR, Brown K, Xu Y, McDuffie LA, Shukla V, Reardon ES, Crooks DR, Trepel JB, Lee S, Lee MJ, Gao S, Xi S, McLoughlin KC, Diggs LP, Beer DG, Nancarrow DJ, Neckers LM, Davis JL, Hoang CD, Hernandez JM, Schrump DS, Ripley RT.

Mol Cancer Ther. 2018 Jun 22. pii: molcanther.1240.2017. doi: 10.1158/1535-7163.MCT-17-1240. [Epub ahead of print]

PMID:
29934340
3.

A Predictive 7-Gene Assay and Prognostic Protein Biomarkers for Non-small Cell Lung Cancer.

Guo NL, Dowlati A, Raese RA, Dong C, Chen G, Beer DG, Shaffer J, Singh S, Bokhary U, Liu L, Howington J, Hensing T, Qian Y.

EBioMedicine. 2018 Jun;32:102-110. doi: 10.1016/j.ebiom.2018.05.025. Epub 2018 Jun 1.

4.

Silencing of Long Noncoding RNA MIR22HG Triggers Cell Survival/Death Signaling via Oncogenes YBX1, MET, and p21 in Lung Cancer.

Su W, Feng S, Chen X, Yang X, Mao R, Guo C, Wang Z, Thomas DG, Lin J, Reddy RM, Orringer MB, Chang AC, Yang Z, Beer DG, Chen G.

Cancer Res. 2018 Jun 15;78(12):3207-3219. doi: 10.1158/0008-5472.CAN-18-0222. Epub 2018 Apr 18.

PMID:
29669758
5.

Use of Appropriate Surveillance for Patients With Nondysplastic Barrett's Esophagus.

Tavakkoli A, Appelman HD, Beer DG, Madiyal C, Khodadost M, Nofz K, Metko V, Elta G, Wang T, Rubenstein JH.

Clin Gastroenterol Hepatol. 2018 Jun;16(6):862-869.e3. doi: 10.1016/j.cgh.2018.01.052. Epub 2018 Feb 9.

PMID:
29432922
6.

Epithelial-mesenchymal transition leads to NK cell-mediated metastasis-specific immunosurveillance in lung cancer.

Chockley PJ, Chen J, Chen G, Beer DG, Standiford TJ, Keshamouni VG.

J Clin Invest. 2018 Apr 2;128(4):1384-1396. doi: 10.1172/JCI97611. Epub 2018 Feb 26.

7.

Increased Variance in Oral and Gastric Microbiome Correlates With Esophagectomy Anastomotic Leak.

Reddy RM, Weir WB, Barnett S, Heiden BT, Orringer MB, Lin J, Chang AC, Carrott PW, Lynch WR, Beer DG, Fenno JC, Kapila Y.

Ann Thorac Surg. 2018 Mar;105(3):865-870. doi: 10.1016/j.athoracsur.2017.08.061. Epub 2018 Jan 5.

PMID:
29307454
8.

Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA.

Hosono Y, Niknafs YS, Prensner JR, Iyer MK, Dhanasekaran SM, Mehra R, Pitchiaya S, Tien J, Escara-Wilke J, Poliakov A, Chu SC, Saleh S, Sankar K, Su F, Guo S, Qiao Y, Freier SM, Bui HH, Cao X, Malik R, Johnson TM, Beer DG, Feng FY, Zhou W, Chinnaiyan AM.

Cell. 2017 Dec 14;171(7):1559-1572.e20. doi: 10.1016/j.cell.2017.11.040.

PMID:
29245011
9.

Identification and validation of FGFR2 peptide for detection of early Barrett's neoplasia.

Zhou J, He L, Pang Z, Appelman HD, Kuick R, Beer DG, Li M, Wang TD.

Oncotarget. 2017 Aug 1;8(50):87095-87106. doi: 10.18632/oncotarget.19764. eCollection 2017 Oct 20.

10.

Genomic regions associated with susceptibility to Barrett's esophagus and esophageal adenocarcinoma in African Americans: The cross BETRNet admixture study.

Sun X, Chandar AK, Canto MI, Thota PN, Brock M, Shaheen NJ, Beer DG, Wang JS, Falk GW, Iyer PG, Abrams JA, Venkat-Ramani M, Veigl M, Miron A, Willis J, Patil DT, Nalbantoglu I, Guda K, Markowitz SD, Zhu X, Elston R, Chak A.

PLoS One. 2017 Oct 26;12(10):e0184962. doi: 10.1371/journal.pone.0184962. eCollection 2017.

11.

Downregulation of miR-99a/let-7c/miR-125b miRNA cluster predicts clinical outcome in patients with unresected malignant pleural mesothelioma.

Truini A, Coco S, Nadal E, Genova C, Mora M, Dal Bello MG, Vanni I, Alama A, Rijavec E, Biello F, Barletta G, Merlo DF, Valentino A, Ferro P, Ravetti GL, Stigliani S, Vigani A, Fedeli F, Beer DG, Roncella S, Grossi F.

Oncotarget. 2017 Aug 2;8(40):68627-68640. doi: 10.18632/oncotarget.19800. eCollection 2017 Sep 15.

12.

Poor Prognosis Indicated by Venous Circulating Tumor Cell Clusters in Early-Stage Lung Cancers.

Murlidhar V, Reddy RM, Fouladdel S, Zhao L, Ishikawa MK, Grabauskiene S, Zhang Z, Lin J, Chang AC, Carrott P, Lynch WR, Orringer MB, Kumar-Sinha C, Palanisamy N, Beer DG, Wicha MS, Ramnath N, Azizi E, Nagrath S.

Cancer Res. 2017 Sep 15;77(18):5194-5206. doi: 10.1158/0008-5472.CAN-16-2072. Epub 2017 Jul 17.

PMID:
28716896
13.

Squamous cell carcinomas and adenocarcinomas of the esophagus: One treatment does not rule them all.

Lagisetty KH, Beer DG, Chang AC.

J Thorac Cardiovasc Surg. 2017 Oct;154(4):1446-1447. doi: 10.1016/j.jtcvs.2017.04.074. Epub 2017 May 22. No abstract available.

PMID:
28666662
14.

Overexpression of LINC00152 correlates with poor patient survival and knockdown impairs cell proliferation in lung cancer.

Feng S, Zhang J, Su W, Bai S, Xiao L, Chen X, Lin J, Reddy RM, Chang AC, Beer DG, Chen G.

Sci Rep. 2017 Jun 7;7(1):2982. doi: 10.1038/s41598-017-03043-x.

15.

Overexpression of FAM83H-AS1 indicates poor patient survival and knockdown impairs cell proliferation and invasion via MET/EGFR signaling in lung cancer.

Zhang J, Feng S, Su W, Bai S, Xiao L, Wang L, Thomas DG, Lin J, Reddy RM, Carrott PW, Lynch WR, Chang AC, Beer DG, Guo YM, Chen G.

Sci Rep. 2017 Feb 15;7:42819. doi: 10.1038/srep42819.

16.

Development of a RNA-Seq Based Prognostic Signature in Lung Adenocarcinoma.

Shukla S, Evans JR, Malik R, Feng FY, Dhanasekaran SM, Cao X, Chen G, Beer DG, Jiang H, Chinnaiyan AM.

J Natl Cancer Inst. 2016 Oct 5;109(1). doi: 10.1093/jnci/djw200. Print 2017 Jan.

17.

Genomic similarity between gastroesophageal junction and esophageal Barrett's adenocarcinomas.

Ferrer-Torres D, Nancarrow DJ, Kuick R, Thomas DG, Nadal E, Lin J, Chang AC, Reddy RM, Orringer MB, Taylor JM, Wang TD, Beer DG.

Oncotarget. 2016 Aug 23;7(34):54867-54882. doi: 10.18632/oncotarget.10253.

18.

Non-coding RNA LINC00857 is predictive of poor patient survival and promotes tumor progression via cell cycle regulation in lung cancer.

Wang L, He Y, Liu W, Bai S, Xiao L, Zhang J, Dhanasekaran SM, Wang Z, Kalyana-Sundaram S, Balbin OA, Shukla S, Lu Y, Lin J, Reddy RM, Carrott PW Jr, Lynch WR, Chang AC, Chinnaiyan AM, Beer DG, Zhang J, Chen G.

Oncotarget. 2016 Mar 8;7(10):11487-99. doi: 10.18632/oncotarget.7203.

19.

Pulmonary venous blood sampling significantly increases the yield of circulating tumor cells in early-stage lung cancer.

Reddy RM, Murlidhar V, Zhao L, Grabauskiene S, Zhang Z, Ramnath N, Lin J, Chang AC, Carrott P, Lynch W, Orringer MB, Beer DG, Nagrath S.

J Thorac Cardiovasc Surg. 2016 Mar;151(3):852-858. doi: 10.1016/j.jtcvs.2015.09.126. Epub 2015 Oct 22.

20.

Using second harmonic generation to predict patient outcome in solid tumors.

Burke K, Smid M, Dawes RP, Timmermans MA, Salzman P, van Deurzen CH, Beer DG, Foekens JA, Brown E.

BMC Cancer. 2015 Nov 24;15:929. doi: 10.1186/s12885-015-1911-8.

21.

Multimodal endoscope can quantify wide-field fluorescence detection of Barrett's neoplasia.

Joshi BP, Duan X, Kwon RS, Piraka C, Elmunzer BJ, Lu S, Rabinsky EF, Beer DG, Appelman HD, Owens SR, Kuick R, Doguchi N, Turgeon DK, Wang TD.

Endoscopy. 2016 Feb;48(2):A1-A13. doi: 10.1055/s-0034-1392803. Epub 2015 Oct 1.

22.

IGFBP2 modulates the chemoresistant phenotype in esophageal adenocarcinoma.

Myers AL, Lin L, Nancarrow DJ, Wang Z, Ferrer-Torres D, Thomas DG, Orringer MB, Lin J, Reddy RM, Beer DG, Chang AC.

Oncotarget. 2015 Sep 22;6(28):25897-916. doi: 10.18632/oncotarget.4532.

23.

A Novel Serum 4-microRNA Signature for Lung Cancer Detection.

Nadal E, Truini A, Nakata A, Lin J, Reddy RM, Chang AC, Ramnath N, Gotoh N, Beer DG, Chen G.

Sci Rep. 2015 Jul 23;5:12464. doi: 10.1038/srep12464.

24.

Paired exome analysis of Barrett's esophagus and adenocarcinoma.

Stachler MD, Taylor-Weiner A, Peng S, McKenna A, Agoston AT, Odze RD, Davison JM, Nason KS, Loda M, Leshchiner I, Stewart C, Stojanov P, Seepo S, Lawrence MS, Ferrer-Torres D, Lin J, Chang AC, Gabriel SB, Lander ES, Beer DG, Getz G, Carter SL, Bass AJ.

Nat Genet. 2015 Sep;47(9):1047-55. doi: 10.1038/ng.3343. Epub 2015 Jul 20.

25.

Role and regulation of coordinately expressed de novo purine biosynthetic enzymes PPAT and PAICS in lung cancer.

Goswami MT, Chen G, Chakravarthi BV, Pathi SS, Anand SK, Carskadon SL, Giordano TJ, Chinnaiyan AM, Thomas DG, Palanisamy N, Beer DG, Varambally S.

Oncotarget. 2015 Sep 15;6(27):23445-61.

26.

The role of Dickkopf-3 overexpression in esophageal adenocarcinoma.

Wang Z, Lin L, Thomas DG, Nadal E, Chang AC, Beer DG, Lin J.

J Thorac Cardiovasc Surg. 2015 Aug;150(2):377-385.e2. doi: 10.1016/j.jtcvs.2015.05.006. Epub 2015 May 8.

27.

MAP3K3 expression in tumor cells and tumor-infiltrating lymphocytes is correlated with favorable patient survival in lung cancer.

He Y, Wang L, Liu W, Zhong J, Bai S, Wang Z, Thomas DG, Lin J, Reddy RM, Ramnath N, Carrott PW, Lynch WR, Orringer MB, Chang AC, Beer DG, Chen G.

Sci Rep. 2015 Jun 19;5:11471. doi: 10.1038/srep11471.

28.

Osteopontin (OPN/SPP1) isoforms collectively enhance tumor cell invasion and dissemination in esophageal adenocarcinoma.

Lin J, Myers AL, Wang Z, Nancarrow DJ, Ferrer-Torres D, Handlogten A, Leverenz K, Bao J, Thomas DG, Wang TD, Orringer MB, Reddy RM, Chang AC, Beer DG, Lin L.

Oncotarget. 2015 Sep 8;6(26):22239-57.

29.

The landscape of antisense gene expression in human cancers.

Balbin OA, Malik R, Dhanasekaran SM, Prensner JR, Cao X, Wu YM, Robinson D, Wang R, Chen G, Beer DG, Nesvizhskii AI, Chinnaiyan AM.

Genome Res. 2015 Jul;25(7):1068-79. doi: 10.1101/gr.180596.114. Epub 2015 Jun 10.

30.

Sensitive, quantitative, and high-throughput detection of angiogenic markers using shape-coded hydrogel microparticles.

Al-Ameen MA, Li J, Beer DG, Ghosh G.

Analyst. 2015 Jul 7;140(13):4530-9. doi: 10.1039/c5an00358j.

PMID:
25988567
31.

Development and validation of a scalable next-generation sequencing system for assessing relevant somatic variants in solid tumors.

Hovelson DH, McDaniel AS, Cani AK, Johnson B, Rhodes K, Williams PD, Bandla S, Bien G, Choppa P, Hyland F, Gottimukkala R, Liu G, Manivannan M, Schageman J, Ballesteros-Villagrana E, Grasso CS, Quist MJ, Yadati V, Amin A, Siddiqui J, Betz BL, Knudsen KE, Cooney KA, Feng FY, Roh MH, Nelson PS, Liu CJ, Beer DG, Wyngaard P, Chinnaiyan AM, Sadis S, Rhodes DR, Tomlins SA.

Neoplasia. 2015 Apr;17(4):385-99. doi: 10.1016/j.neo.2015.03.004.

32.

Monoclonal antibodies specific for oncofetal antigen--immature laminin receptor protein: Effects on tumor growth and spread in two murine models.

McClintock SD, Warner RL, Ali S, Chekuri A, Dame MK, Attili D, Knibbs RK, Aslam MN, Sinkule J, Morgan AC, Barsoum A, Smith LB, Beer DG, Johnson KJ, Varani J.

Cancer Biol Ther. 2015;16(5):724-32. doi: 10.1080/15384047.2015.1026484.

33.

Cigarette smoke mediates epigenetic repression of miR-217 during esophageal adenocarcinogenesis.

Xi S, Inchauste S, Guo H, Shan J, Xiao Z, Xu H, Miettenen M, Zhang MR, Hong JA, Raiji MT, Altorki NK, Casson AG, Beer DG, Robles AI, Bowman ED, Harris CC, Steinberg SM, Schrump DS.

Oncogene. 2015 Oct 29;34(44):5548-59. doi: 10.1038/onc.2015.10. Epub 2015 Feb 23.

PMID:
25703328
34.

Phosphorylation of FADD by the kinase CK1α promotes KRASG12D-induced lung cancer.

Bowman BM, Sebolt KA, Hoff BA, Boes JL, Daniels DL, Heist KA, Galbán CJ, Patel RM, Zhang J, Beer DG, Ross BD, Rehemtulla A, Galbán S.

Sci Signal. 2015 Jan 27;8(361):ra9. doi: 10.1126/scisignal.2005607. Erratum in: Sci Signal. 2015 Mar 17;8(368):er3.

35.

KRAS-G12C mutation is associated with poor outcome in surgically resected lung adenocarcinoma.

Nadal E, Beer DG, Ramnath N.

J Thorac Oncol. 2015 Feb;10(2):e9-10. doi: 10.1097/JTO.0000000000000438. No abstract available.

36.

The landscape of long noncoding RNAs in the human transcriptome.

Iyer MK, Niknafs YS, Malik R, Singhal U, Sahu A, Hosono Y, Barrette TR, Prensner JR, Evans JR, Zhao S, Poliakov A, Cao X, Dhanasekaran SM, Wu YM, Robinson DR, Beer DG, Feng FY, Iyer HK, Chinnaiyan AM.

Nat Genet. 2015 Mar;47(3):199-208. doi: 10.1038/ng.3192. Epub 2015 Jan 19.

37.

Transcriptome meta-analysis of lung cancer reveals recurrent aberrations in NRG1 and Hippo pathway genes.

Dhanasekaran SM, Balbin OA, Chen G, Nadal E, Kalyana-Sundaram S, Pan J, Veeneman B, Cao X, Malik R, Vats P, Wang R, Huang S, Zhong J, Jing X, Iyer M, Wu YM, Harms PW, Lin J, Reddy R, Brennan C, Palanisamy N, Chang AC, Truini A, Truini M, Robinson DR, Beer DG, Chinnaiyan AM.

Nat Commun. 2014 Dec 22;5:5893. doi: 10.1038/ncomms6893.

38.

Expansion of CTCs from early stage lung cancer patients using a microfluidic co-culture model.

Zhang Z, Shiratsuchi H, Lin J, Chen G, Reddy RM, Azizi E, Fouladdel S, Chang AC, Lin L, Jiang H, Waghray M, Luker G, Simeone DM, Wicha MS, Beer DG, Ramnath N, Nagrath S.

Oncotarget. 2014 Dec 15;5(23):12383-97.

39.

KRAS-G12C mutation is associated with poor outcome in surgically resected lung adenocarcinoma.

Nadal E, Chen G, Prensner JR, Shiratsuchi H, Sam C, Zhao L, Kalemkerian GP, Brenner D, Lin J, Reddy RM, Chang AC, Capellà G, Cardenal F, Beer DG, Ramnath N.

J Thorac Oncol. 2014 Oct;9(10):1513-22. doi: 10.1097/JTO.0000000000000305.

40.

Telomerase variant A279T induces telomere dysfunction and inhibits non-canonical telomerase activity in esophageal carcinomas.

Zhang Y, Calado R, Rao M, Hong JA, Meeker AK, Dumitriu B, Atay S, McCormick PJ, Garfield SH, Wangsa D, Padilla-Nash HM, Burkett S, Zhang M, Kunst TF, Peterson NR, Xi S, Inchauste S, Altorki NK, Casson AG, Beer DG, Harris CC, Ried T, Young NS, Schrump DS.

PLoS One. 2014 Jul 1;9(7):e101010. doi: 10.1371/journal.pone.0101010. eCollection 2014.

41.

A MicroRNA cluster at 14q32 drives aggressive lung adenocarcinoma.

Nadal E, Zhong J, Lin J, Reddy RM, Ramnath N, Orringer MB, Chang AC, Beer DG, Chen G.

Clin Cancer Res. 2014 Jun 15;20(12):3107-17. doi: 10.1158/1078-0432.CCR-13-3348. Epub 2014 May 15.

42.

TGM2: a cell surface marker in esophageal adenocarcinomas.

Leicht DT, Kausar T, Wang Z, Ferrer-Torres D, Wang TD, Thomas DG, Lin J, Chang AC, Lin L, Beer DG.

J Thorac Oncol. 2014 Jun;9(6):872-81. doi: 10.1097/JTO.0000000000000229.

43.

Barrett's Esophagus Translational Research Network (BETRNet): the pivotal role of multi-institutional collaboration in esophageal adenocarcinoma research.

Abrams JA, Appelman HD, Beer DG, Berry LD, Chak A, Falk GW, Fitzgerald RC, Ginsberg GG, Grady WM, Joshi BP, Lynch JP, Markowitz S, Richmond ES, Rustgi AK, Seibel EJ, Shaheen NJ, Shyr Y, Umar A, Wang KK, Wang TC, Wang TD, Yassin R.

Gastroenterology. 2014 Jun;146(7):1586-90. doi: 10.1053/j.gastro.2014.04.014. Epub 2014 Apr 21. No abstract available.

44.

Epigenetic regulation of vitamin D metabolism in human lung adenocarcinoma.

Ramnath N, Nadal E, Jeon CK, Sandoval J, Colacino J, Rozek LS, Christensen PJ, Esteller M, Beer DG, Kim SH.

J Thorac Oncol. 2014 Apr;9(4):473-82. doi: 10.1097/JTO.0000000000000114.

45.

KRAS protein stability is regulated through SMURF2: UBCH5 complex-mediated β-TrCP1 degradation.

Shukla S, Allam US, Ahsan A, Chen G, Krishnamurthy PM, Marsh K, Rumschlag M, Shankar S, Whitehead C, Schipper M, Basrur V, Southworth DR, Chinnaiyan AM, Rehemtulla A, Beer DG, Lawrence TS, Nyati MK, Ray D.

Neoplasia. 2014 Feb;16(2):115-28. doi: 10.1593/neo.14184.

46.

Epithelial-mesenchymal transition-associated secretory phenotype predicts survival in lung cancer patients.

Reka AK, Chen G, Jones RC, Amunugama R, Kim S, Karnovsky A, Standiford TJ, Beer DG, Omenn GS, Keshamouni VG.

Carcinogenesis. 2014 Jun;35(6):1292-300. doi: 10.1093/carcin/bgu041. Epub 2014 Feb 7.

47.

Comparison of cancer-associated genetic abnormalities in columnar-lined esophagus tissues with and without goblet cells.

Bandla S, Peters JH, Ruff D, Chen SM, Li CY, Song K, Thoms K, Litle VR, Watson T, Chapurin N, Lada M, Pennathur A, Luketich JD, Peterson D, Dulak A, Lin L, Bass A, Beer DG, Godfrey TE, Zhou Z.

Ann Surg. 2014 Jul;260(1):72-80. doi: 10.1097/SLA.0000000000000424.

48.

Inactivation of SAG/RBX2 E3 ubiquitin ligase suppresses KrasG12D-driven lung tumorigenesis.

Li H, Tan M, Jia L, Wei D, Zhao Y, Chen G, Xu J, Zhao L, Thomas D, Beer DG, Sun Y.

J Clin Invest. 2014 Feb;124(2):835-46. doi: 10.1172/JCI70297. Epub 2014 Jan 16.

49.

Checkpoint kinase 1 protein expression indicates sensitization to therapy by checkpoint kinase 1 inhibition in non-small cell lung cancer.

Grabauskiene S, Bergeron EJ, Chen G, Thomas DG, Giordano TJ, Beer DG, Morgan MA, Reddy RM.

J Surg Res. 2014 Mar;187(1):6-13. doi: 10.1016/j.jss.2013.12.016. Epub 2013 Dec 18.

50.

Reconstructing targetable pathways in lung cancer by integrating diverse omics data.

Balbin OA, Prensner JR, Sahu A, Yocum A, Shankar S, Malik R, Fermin D, Dhanasekaran SM, Chandler B, Thomas D, Beer DG, Cao X, Nesvizhskii AI, Chinnaiyan AM.

Nat Commun. 2013;4:2617. doi: 10.1038/ncomms3617.

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