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Items: 9


Bi-directional allelic recognition of the human minor histocompatibility antigen HB-1 by cytotoxic T lymphocytes.

Dolstra H, de Rijke B, Fredrix H, Balas A, Maas F, Scherpen F, Aviles MJ, Vicario JL, Beekman NJ, Ossendorp F, de Witte TM, van de Wiel-van Kemenade E.

Eur J Immunol. 2002 Oct;32(10):2748-58.


The nature of the bond between peptide and carrier molecule determines the immunogenicity of the construct.

Beekman NJ, Schaaper WM, Langeveld JP, Boshuizen RS, Meloen RH.

J Pept Res. 2001 Sep;58(3):237-45.


Efficient identification of novel HLA-A(*)0201-presented cytotoxic T lymphocyte epitopes in the widely expressed tumor antigen PRAME by proteasome-mediated digestion analysis.

Kessler JH, Beekman NJ, Bres-Vloemans SA, Verdijk P, van Veelen PA, Kloosterman-Joosten AM, Vissers DC, ten Bosch GJ, Kester MG, Sijts A, Wouter Drijfhout J, Ossendorp F, Offringa R, Melief CJ.

J Exp Med. 2001 Jan 1;193(1):73-88.


MHC class I antigen processing of an adenovirus CTL epitope is linked to the levels of immunoproteasomes in infected cells.

Sijts AJ, Standera S, Toes RE, Ruppert T, Beekman NJ, van Veelen PA, Ossendorp FA, Melief CJ, Kloetzel PM.

J Immunol. 2000 May 1;164(9):4500-6.


Abrogation of CTL epitope processing by single amino acid substitution flanking the C-terminal proteasome cleavage site.

Beekman NJ, van Veelen PA, van Hall T, Neisig A, Sijts A, Camps M, Kloetzel PM, Neefjes JJ, Melief CJ, Ossendorp F.

J Immunol. 2000 Feb 15;164(4):1898-905.


Highly immunogenic and fully synthetic peptide-carrier constructs targetting GnRH.

Beekman NJ, Schaaper WM, Turkstra JA, Meloen RH.

Vaccine. 1999 Apr 9;17(15-16):2043-50.


Synthetic peptide vaccines: palmitoylation of peptide antigens by a thioester bond increases immunogenicity.

Beekman NJ, Schaaper WM, Tesser GI, Dalsgaard K, Kamstrup S, Langeveld JP, Boshuizen RS, Meloen RH.

J Pept Res. 1997 Nov;50(5):357-64.


Full protection in mink against mink enteritis virus with new generation canine parvovirus vaccines based on synthetic peptide or recombinant protein.

Langeveld JP, Kamstrup S, Uttenthal A, Strandbygaard B, Vela C, Dalsgaard K, Beekman NJ, Meloen RH, Casal JI.

Vaccine. 1995 Aug;13(11):1033-7.


Synthetic peptides based upon a three-dimensional model for the receptor recognition site of follicle-stimulating hormone exhibit antagonistic or agonistic activity at low concentrations.

Hage-van Noort M, Puijk WC, Plasman HH, Kuperus D, Schaaper WM, Beekman NJ, Grootegoed JA, Meloen RH.

Proc Natl Acad Sci U S A. 1992 May 1;89(9):3922-6. Erratum in: Proc Natl Acad Sci U S A 1993 Dec 15;90(24):12056.

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