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Items: 32

1.

Development of mucoadhesive vaginal films based on HPMC and zein as novel formulations to prevent sexual transmission of HIV.

Notario-Pérez F, Martín-Illana A, Cazorla-Luna R, Ruiz-Caro R, Bedoya LM, Peña J, Veiga MD.

Int J Pharm. 2019 Oct 30;570:118643. doi: 10.1016/j.ijpharm.2019.118643. Epub 2019 Aug 22.

PMID:
31446023
2.

Dapivirine Bioadhesive Vaginal Tablets Based on Natural Polymers for the Prevention of Sexual Transmission of HIV.

Cazorla-Luna R, Martín-Illana A, Notario-Pérez F, Bedoya LM, Bermejo P, Ruiz-Caro R, Veiga MD.

Polymers (Basel). 2019 Mar 13;11(3). pii: E483. doi: 10.3390/polym11030483.

3.

Freeze-dried bioadhesive vaginal bigels for controlled release of Tenofovir.

Martín-Illana A, Cazorla-Luna R, Notario-Pérez F, Bedoya LM, Ruiz-Caro R, Veiga MD.

Eur J Pharm Sci. 2019 Jan 15;127:38-51. doi: 10.1016/j.ejps.2018.10.013. Epub 2018 Oct 19.

PMID:
30343152
4.

A small-molecule inhibitor of HIV-1 Rev function detected by a diversity screen based on RRE-Rev interference.

Prado S, Beltrán M, Moreno Á, Bedoya LM, Alcamí J, Gallego J.

Biochem Pharmacol. 2018 Oct;156:68-77. doi: 10.1016/j.bcp.2018.07.040. Epub 2018 Jul 31.

PMID:
30071201
5.

Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets.

Bedoya LM, Beltrán M, García-Pérez J, Obregón-Calderón P, Callies O, Jímenez IA, Bazzocchi IL, Alcamí J.

Front Pharmacol. 2018 Apr 18;9:358. doi: 10.3389/fphar.2018.00358. eCollection 2018.

6.

Environmentally Friendly Procedure Based on Supercritical Fluid Chromatography and Tandem Mass Spectrometry Molecular Networking for the Discovery of Potent Antiviral Compounds from Euphorbia semiperfoliata.

Nothias LF, Boutet-Mercey S, Cachet X, De La Torre E, Laboureur L, Gallard JF, Retailleau P, Brunelle A, Dorrestein PC, Costa J, Bedoya LM, Roussi F, Leyssen P, Alcami J, Paolini J, Litaudon M, Touboul D.

J Nat Prod. 2017 Oct 27;80(10):2620-2629. doi: 10.1021/acs.jnatprod.7b00113. Epub 2017 Sep 19.

PMID:
28925702
7.

Influence of Chitosan Swelling Behaviour on Controlled Release of Tenofovir from Mucoadhesive Vaginal Systems for Prevention of Sexual Transmission of HIV.

Notario-Pérez F, Martín-Illana A, Cazorla-Luna R, Ruiz-Caro R, Bedoya LM, Tamayo A, Rubio J, Veiga MD.

Mar Drugs. 2017 Feb 21;15(2). pii: E50. doi: 10.3390/md15020050.

8.

Neoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways.

Olmedo DA, López-Pérez JL, Del Olmo E, Bedoya LM, Sancho R, Alcamí J, Muñoz E, Feliciano AS, Gupta MP.

Molecules. 2017 Feb 19;22(2). pii: E321. doi: 10.3390/molecules22020321.

9.

Hydroxytyrosol: a new class of microbicide displaying broad anti-HIV-1 activity.

Bedoya LM, Beltrán M, Obregón-Calderón P, García-Pérez J, de la Torre HE, González N, Pérez-Olmeda M, Auñón D, Capa L, Gómez-Acebo E, Alcamí J.

AIDS. 2016 Nov 28;30(18):2767-2776.

10.

Bioavailable inhibitors of HIV-1 RNA biogenesis identified through a Rev-based screen.

Prado S, Beltrán M, Coiras M, Bedoya LM, Alcamí J, Gallego J.

Biochem Pharmacol. 2016 May 1;107:14-28. doi: 10.1016/j.bcp.2016.02.007. Epub 2016 Feb 17.

PMID:
26896646
11.

Chitosan and Kappa-Carrageenan Vaginal Acyclovir Formulations for Prevention of Genital Herpes. In Vitro and Ex Vivo Evaluation.

Sánchez-Sánchez MP, Martín-Illana A, Ruiz-Caro R, Bermejo P, Abad MJ, Carro R, Bedoya LM, Tamayo A, Rubio J, Fernández-Ferreiro A, Otero-Espinar F, Veiga MD.

Mar Drugs. 2015 Sep 18;13(9):5976-92. doi: 10.3390/md13095976.

12.

Isolation, Structural Modification, and HIV Inhibition of Pentacyclic Lupane-Type Triterpenoids from Cassine xylocarpa and Maytenus cuzcoina.

Callies O, Bedoya LM, Beltrán M, Muñoz A, Calderón PO, Osorio AA, Jiménez IA, Alcamí J, Bazzocchi IL.

J Nat Prod. 2015 May 22;78(5):1045-55. doi: 10.1021/np501025r. Epub 2015 Apr 30.

PMID:
25927586
13.

Negatively charged glyconanoparticles modulate and stabilize the secondary structures of a gp120 V3 loop peptide: toward fully synthetic HIV vaccine candidates.

Gianvincenzo PD, Calvo J, Perez S, Álvarez A, Bedoya LM, Alcamí J, Penadés S.

Bioconjug Chem. 2015 Apr 15;26(4):755-65. doi: 10.1021/acs.bioconjchem.5b00077. Epub 2015 Mar 11.

PMID:
25734507
14.

Structure-based design of an RNA-binding p-terphenylene scaffold that inhibits HIV-1 Rev protein function.

González-Bulnes L, Ibáñez I, Bedoya LM, Beltrán M, Catalán S, Alcamí J, Fustero S, Gallego J.

Angew Chem Int Ed Engl. 2013 Dec 9;52(50):13405-9. doi: 10.1002/anie.201306665. Epub 2013 Nov 8. No abstract available.

PMID:
24214163
15.

3-Phenylcoumarins as inhibitors of HIV-1 replication.

Olmedo D, Sancho R, Bedoya LM, López-Pérez JL, Del Olmo E, Muñoz E, Alcamí J, Gupta MP, San Feliciano A.

Molecules. 2012 Aug 2;17(8):9245-57. doi: 10.3390/molecules17089245.

16.

Olean-18-ene triterpenoids from Celastraceae species inhibit HIV replication targeting NF-kB and Sp1 dependent transcription.

Osorio AA, Muñóz A, Torres-Romero D, Bedoya LM, Perestelo NR, Jiménez IA, Alcamí J, Bazzocchi IL.

Eur J Med Chem. 2012 Jun;52:295-303. doi: 10.1016/j.ejmech.2012.03.035. Epub 2012 Mar 28.

PMID:
22487595
17.

The artemisia L. Genus: a review of bioactive essential oils.

Abad MJ, Bedoya LM, Apaza L, Bermejo P.

Molecules. 2012 Mar 2;17(3):2542-66. doi: 10.3390/molecules17032542. Review.

18.

Quinoline-based compounds as modulators of HIV transcription through NF-kappaB and Sp1 inhibition.

Bedoya LM, Abad MJ, Calonge E, Saavedra LA, Gutierrez C M, Kouznetsov VV, Alcami J, Bermejo P.

Antiviral Res. 2010 Sep;87(3):338-44. doi: 10.1016/j.antiviral.2010.06.006. Epub 2010 Jun 23.

PMID:
20600334
19.

Gold nanoparticles capped with sulfate-ended ligands as anti-HIV agents.

Di Gianvincenzo P, Marradi M, Martínez-Avila OM, Bedoya LM, Alcamí J, Penadés S.

Bioorg Med Chem Lett. 2010 May 1;20(9):2718-21. doi: 10.1016/j.bmcl.2010.03.079. Epub 2010 Mar 25.

PMID:
20382017
20.

An update on drug interactions with the herbal medicine Ginkgo biloba.

Abad MJ, Bedoya LM, Bermejo P.

Curr Drug Metab. 2010 Feb;11(2):171-81. Review.

PMID:
20359286
21.

Ellagitannins from Tuberaria lignosa as entry inhibitors of HIV.

Bedoya LM, Abad MJ, Sánchez-Palomino S, Alcami J, Bermejo P.

Phytomedicine. 2010 Jan;17(1):69-74. doi: 10.1016/j.phymed.2009.08.008. Epub 2009 Sep 11.

PMID:
19748255
22.

Multivalent manno-glyconanoparticles inhibit DC-SIGN-mediated HIV-1 trans-infection of human T cells.

Martínez-Avila O, Bedoya LM, Marradi M, Clavel C, Alcamí J, Penadés S.

Chembiochem. 2009 Jul 20;10(11):1806-9. doi: 10.1002/cbic.200900294. No abstract available.

PMID:
19565596
23.

Anti-infectious activity in the Cistaceae family in the Iberian Peninsula.

Bedoya LM, Bermejo P, Abad MJ.

Mini Rev Med Chem. 2009 May;9(5):519-25. Review.

PMID:
19456283
24.

SJ23B, a jatrophane diterpene activates classical PKCs and displays strong activity against HIV in vitro.

Bedoya LM, Márquez N, Martínez N, Gutiérrez-Eisman S, Alvarez A, Calzado MA, Rojas JM, Appendino G, Muñoz E, Alcamí J.

Biochem Pharmacol. 2009 Mar 15;77(6):965-78. doi: 10.1016/j.bcp.2008.11.025. Epub 2008 Dec 3.

PMID:
19100719
25.

Natural marine anti-inflammatory products.

Abad MJ, Bedoya LM, Bermejo P.

Mini Rev Med Chem. 2008 Jul;8(8):740-54. Review.

PMID:
18673130
26.

Guatemalan plants extracts as virucides against HIV-1 infection.

Bedoya LM, Alvarez A, Bermejo M, González N, Beltrán M, Sánchez-Palomino S, Cruz SM, Gaitán I, del Olmo E, Escarcena R, García PA, Cáceres A, San Feliciano A, Alcamí J.

Phytomedicine. 2008 Jun;15(6-7):520-4. Epub 2008 Feb 20.

PMID:
18068962
27.

Anti-HIV activity of stilbene-related heterocyclic compounds.

Bedoya LM, del Olmo E, Sancho R, Barboza B, Beltrán M, García-Cadenas AE, Sánchez-Palomino S, López-Pérez JL, Muñoz E, San Feliciano A, Alcamí J.

Bioorg Med Chem Lett. 2006 Aug 1;16(15):4075-9. Epub 2006 May 18.

PMID:
16713260
28.

4-Phenylcoumarins as HIV transcription inhibitors.

Bedoya LM, Beltrán M, Sancho R, Olmedo DA, Sánchez-Palomino S, del Olmo E, López-Pérez JL, Muñoz E, San Feliciano A, Alcamí J.

Bioorg Med Chem Lett. 2005 Oct 15;15(20):4447-50.

PMID:
16137881
29.

Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-kappaB pathway.

Márquez N, Sancho R, Bedoya LM, Alcamí J, López-Pérez JL, Feliciano AS, Fiebich BL, Muñoz E.

Antiviral Res. 2005 Jun;66(2-3):137-45. Epub 2005 Apr 20.

PMID:
15911030
30.

Screening of selected plant extracts for in vitro inhibitory activity on human immunodeficiency virus.

Bedoya LM, Palomino SS, Abad MJ, Bermejo P, Alcami J.

Phytother Res. 2002 Sep;16(6):550-4.

PMID:
12237813
31.

Screening of South American plants against human immunodeficiency virus: preliminary fractionation of aqueous extract from Baccharis trinervis.

Sanchez Palomino S, Abad MJ, Bedoya LM, García J, Gonzales E, Chiriboga X, Bermejo P, Alcami J.

Biol Pharm Bull. 2002 Sep;25(9):1147-50.

32.

Anti-HIV activity of medicinal plant extracts.

Bedoya LM, Sanchez-Palomino S, Abad MJ, Bermejo P, Alcami J.

J Ethnopharmacol. 2001 Sep;77(1):113-6.

PMID:
11483387

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