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Items: 32


Contextual role of E2F1 in suppression of melanoma cell motility and invasiveness.

Meng P, Bedolla RG, Yun H, Fitzpatrick JE, Kumar AP, Ghosh R.

Mol Carcinog. 2019 Sep;58(9):1701-1710. doi: 10.1002/mc.23043. Epub 2019 May 23.


Receptor tyrosine kinase recepteur d'origine nantais as predictive marker for aggressive prostate cancer in African Americans.

Bedolla RG, Shah DP, Huang SB, Reddick RL, Ghosh R, Kumar AP.

Mol Carcinog. 2019 Jun;58(6):854-861. doi: 10.1002/mc.23002. Epub 2019 Mar 11.


BRCA1 Interacting Protein COBRA1 Facilitates Adaptation to Castrate-Resistant Growth Conditions.

Yun H, Bedolla R, Horning A, Li R, Chiang HC, Huang TH, Reddick R, Olumi AF, Ghosh R, Kumar AP.

Int J Mol Sci. 2018 Jul 20;19(7). pii: E2104. doi: 10.3390/ijms19072104.


Suppression of ribosomal protein RPS6KB1 by Nexrutine increases sensitivity of prostate tumors to radiation.

Hussain SS, Huang SB, Bedolla RG, Rivas P, Basler JW, Swanson GP, Hui-Ming Huang T, Narayanasamy G, Papanikolaou N, Miyamoto H, Yeh IT, Reddick RL, Pollock BH, Ghosh R, Kumar AP.

Cancer Lett. 2018 Oct 1;433:232-241. doi: 10.1016/j.canlet.2018.07.009. Epub 2018 Jul 9.


SETD6 regulates NF-κB signaling in urothelial cell survival: Implications for bladder cancer.

Mukherjee N, Cardenas E, Bedolla R, Ghosh R.

Oncotarget. 2017 Feb 28;8(9):15114-15125. doi: 10.18632/oncotarget.14750.


Crosstalk between RON and androgen receptor signaling in the development of castration resistant prostate cancer.

Batth I, Yun H, Hussain S, Meng P, Osmulski P, Huang TH, Bedolla R, Profit A, Reddick R, Kumar A.

Oncotarget. 2016 Mar 22;7(12):14048-63. doi: 10.18632/oncotarget.7287.


NQO1 suppresses NF-κB-p300 interaction to regulate inflammatory mediators associated with prostate tumorigenesis.

Thapa D, Meng P, Bedolla RG, Reddick RL, Kumar AP, Ghosh R.

Cancer Res. 2014 Oct 1;74(19):5644-55. doi: 10.1158/0008-5472.CAN-14-0562. Epub 2014 Aug 14.


Combined targeting of STAT3/NF-κB/COX-2/EP4 for effective management of pancreatic cancer.

Gong J, Xie J, Bedolla R, Rivas P, Chakravarthy D, Freeman JW, Reddick R, Kopetz S, Peterson A, Wang H, Fischer SM, Kumar AP.

Clin Cancer Res. 2014 Mar 1;20(5):1259-73. doi: 10.1158/1078-0432.CCR-13-1664. Epub 2014 Feb 11.


Viral cyclin promotes KSHV-induced cellular transformation and tumorigenesis by overriding contact inhibition.

Jones T, Ramos da Silva S, Bedolla R, Ye F, Zhou F, Gao SJ.

Cell Cycle. 2014;13(5):845-58. doi: 10.4161/cc.27758. Epub 2014 Jan 13.


KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways.

Moody R, Zhu Y, Huang Y, Cui X, Jones T, Bedolla R, Lei X, Bai Z, Gao SJ.

PLoS Pathog. 2013;9(12):e1003857. doi: 10.1371/journal.ppat.1003857. Epub 2013 Dec 26. Erratum in: PLoS Pathog. 2014 Jan;10(1). doi:10.1371/annotation/582f0298-9999-46ea-be7e-6718608b11c5.


Dietary resveratrol prevents development of high-grade prostatic intraepithelial neoplastic lesions: involvement of SIRT1/S6K axis.

Li G, Rivas P, Bedolla R, Thapa D, Reddick RL, Ghosh R, Kumar AP.

Cancer Prev Res (Phila). 2013 Jan;6(1):27-39. doi: 10.1158/1940-6207.CAPR-12-0349. Epub 2012 Dec 17.


Predictive value of Sp1/Sp3/FLIP signature for prostate cancer recurrence.

Bedolla RG, Gong J, Prihoda TJ, Yeh IT, Thompson IM, Ghosh R, Kumar AP.

PLoS One. 2012;7(9):e44917. doi: 10.1371/journal.pone.0044917. Epub 2012 Sep 13.


Enhancing the effectiveness of androgen deprivation in prostate cancer by inducing Filamin A nuclear localization.

Mooso BA, Vinall RL, Tepper CG, Savoy RM, Cheung JP, Singh S, Siddiqui S, Wang Y, Bedolla RG, Martinez A, Mudryj M, Kung HJ, Devere White RW, Ghosh PM.

Endocr Relat Cancer. 2012 Nov 9;19(6):759-77. doi: 10.1530/ERC-12-0171. Print 2012 Dec.


Direct and efficient cellular transformation of primary rat mesenchymal precursor cells by KSHV.

Jones T, Ye F, Bedolla R, Huang Y, Meng J, Qian L, Pan H, Zhou F, Moody R, Wagner B, Arar M, Gao SJ.

J Clin Invest. 2012 Mar;122(3):1076-81. doi: 10.1172/JCI58530. Epub 2012 Feb 1.


Reactive oxygen species hydrogen peroxide mediates Kaposi's sarcoma-associated herpesvirus reactivation from latency.

Ye F, Zhou F, Bedolla RG, Jones T, Lei X, Kang T, Guadalupe M, Gao SJ.

PLoS Pathog. 2011 May;7(5):e1002054. doi: 10.1371/journal.ppat.1002054. Epub 2011 May 19.


Nrdp1-mediated regulation of ErbB3 expression by the androgen receptor in androgen-dependent but not castrate-resistant prostate cancer cells.

Chen L, Siddiqui S, Bose S, Mooso B, Asuncion A, Bedolla RG, Vinall R, Tepper CG, Gandour-Edwards R, Shi X, Lu XH, Siddiqui J, Chinnaiyan AM, Mehra R, Devere White RW, Carraway KL 3rd, Ghosh PM.

Cancer Res. 2010 Jul 15;70(14):5994-6003. doi: 10.1158/0008-5472.CAN-09-4440. Epub 2010 Jun 29.


The chemokine CXCL16 and its receptor, CXCR6, as markers and promoters of inflammation-associated cancers.

Darash-Yahana M, Gillespie JW, Hewitt SM, Chen YY, Maeda S, Stein I, Singh SP, Bedolla RB, Peled A, Troyer DA, Pikarsky E, Karin M, Farber JM.

PLoS One. 2009 Aug 19;4(8):e6695. doi: 10.1371/journal.pone.0006695.


Involvement of FLIP in 2-methoxyestradiol-induced tumor regression in transgenic adenocarcinoma of mouse prostate model.

Ganapathy M, Ghosh R, Jianping X, Zhang X, Bedolla R, Schoolfield J, Yeh IT, Troyer DA, Olumi AF, Kumar AP.

Clin Cancer Res. 2009 Mar 1;15(5):1601-11. doi: 10.1158/1078-0432.CCR-08-1389. Epub 2009 Feb 17.


Nuclear versus cytoplasmic localization of filamin A in prostate cancer: immunohistochemical correlation with metastases.

Bedolla RG, Wang Y, Asuncion A, Chamie K, Siddiqui S, Mudryj MM, Prihoda TJ, Siddiqui J, Chinnaiyan AM, Mehra R, de Vere White RW, Ghosh PM.

Clin Cancer Res. 2009 Feb 1;15(3):788-96. doi: 10.1158/1078-0432.CCR-08-1402.


AKT regulates androgen receptor-dependent growth and PSA expression in prostate cancer.

Mikhailova M, Wang Y, Bedolla R, Lu XH, Kreisberg JI, Ghosh PM.

Adv Exp Med Biol. 2008;617:397-405. doi: 10.1007/978-0-387-69080-3_38.


Characterization of PacMetUT1, a recently isolated human prostate cancer cell line.

Troyer DA, Tang Y, Bedolla R, Adhvaryu SG, Thompson IM, Abboud-Werner S, Sun LZ, Friedrichs WE, deGraffenried LA.

Prostate. 2008 Jun 1;68(8):883-92. doi: 10.1002/pros.20758.


Determining risk of biochemical recurrence in prostate cancer by immunohistochemical detection of PTEN expression and Akt activation.

Bedolla R, Prihoda TJ, Kreisberg JI, Malik SN, Krishnegowda NK, Troyer DA, Ghosh PM.

Clin Cancer Res. 2007 Jul 1;13(13):3860-7.


A 90 kDa fragment of filamin A promotes Casodex-induced growth inhibition in Casodex-resistant androgen receptor positive C4-2 prostate cancer cells.

Wang Y, Kreisberg JI, Bedolla RG, Mikhailova M, deVere White RW, Ghosh PM.

Oncogene. 2007 Sep 6;26(41):6061-70. Epub 2007 Apr 9.


Signal transduction pathways in androgen-dependent and -independent prostate cancer cell proliferation.

Ghosh PM, Malik SN, Bedolla RG, Wang Y, Mikhailova M, Prihoda TJ, Troyer DA, Kreisberg JI.

Endocr Relat Cancer. 2005 Mar;12(1):119-34.


Phosphorylation of Akt (Ser473) is an excellent predictor of poor clinical outcome in prostate cancer.

Kreisberg JI, Malik SN, Prihoda TJ, Bedolla RG, Troyer DA, Kreisberg S, Ghosh PM.

Cancer Res. 2004 Aug 1;64(15):5232-6.


Role of protein kinase C in arginine vasopressin-stimulated ERK and p70S6 kinase phosphorylation.

Ghosh PM, Bedolla R, Thomas CA, Kreisberg JI.

J Cell Biochem. 2004 Apr 15;91(6):1109-29.


Akt in prostate cancer: possible role in androgen-independence.

Ghosh PM, Malik S, Bedolla R, Kreisberg JI.

Curr Drug Metab. 2003 Dec;4(6):487-96. Review.


Immunohistochemical determination of EGFR-tyrosine kinase inhibition in clinical samples.

Malik SN, Bedolla RG, Hidalgo M, Brattain MG, Kreisberg JI.

Methods Mol Med. 2003;85:135-40. Review. No abstract available.


RhoA-dependent murine prostate cancer cell proliferation and apoptosis: role of protein kinase Czeta.

Ghosh PM, Bedolla R, Mikhailova M, Kreisberg JI.

Cancer Res. 2002 May 1;62(9):2630-6.


Immunohistochemical demonstration of phospho-Akt in high Gleason grade prostate cancer.

Malik SN, Brattain M, Ghosh PM, Troyer DA, Prihoda T, Bedolla R, Kreisberg JI.

Clin Cancer Res. 2002 Apr;8(4):1168-71.


Arginine vasopressin stimulates mesangial cell proliferation by activating the epidermal growth factor receptor.

Ghosh PM, Mikhailova M, Bedolla R, Kreisberg JI.

Am J Physiol Renal Physiol. 2001 Jun;280(6):F972-9.


Tyrosine phosphorylation of focal adhesion kinase (p125FAK): regulation by cAMP and thrombin in mesangial cells.

Troyer DA, Bouton A, Bedolla R, Padilla R.

J Am Soc Nephrol. 1996 Mar;7(3):415-23.

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