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Items: 1 to 50 of 174

1.

Ancient Rome: A genetic crossroads of Europe and the Mediterranean.

Antonio ML, Gao Z, Moots HM, Lucci M, Candilio F, Sawyer S, Oberreiter V, Calderon D, Devitofranceschi K, Aikens RC, Aneli S, Bartoli F, Bedini A, Cheronet O, Cotter DJ, Fernandes DM, Gasperetti G, Grifoni R, Guidi A, La Pastina F, Loreti E, Manacorda D, Matullo G, Morretta S, Nava A, Fiocchi Nicolai V, Nomi F, Pavolini C, Pentiricci M, Pergola P, Piranomonte M, Schmidt R, Spinola G, Sperduti A, Rubini M, Bondioli L, Coppa A, Pinhasi R, Pritchard JK.

Science. 2019 Nov 8;366(6466):708-714. doi: 10.1126/science.aay6826.

PMID:
31699931
2.

Reactive oxygen species (ROS) generation is stimulated by κ opioid receptor activation through phosphorylated c-Jun N-terminal kinase and inhibited by p38 mitogen-activated protein kinase (MAPK) activation.

Schattauer SS, Bedini A, Summers F, Reilly-Treat A, Andrews MM, Land BB, Chavkin C.

J Biol Chem. 2019 Nov 8;294(45):16884-16896. doi: 10.1074/jbc.RA119.009592. Epub 2019 Oct 1.

PMID:
31575661
3.

Ultrasound delivery of Surface Enhanced InfraRed Absorption active gold-nanoprobes into fibroblast cells: a biological study via Synchrotron-based InfraRed microanalysis at single cell level.

Domenici F, Capocefalo A, Brasili F, Bedini A, Giliberti C, Palomba R, Silvestri I, Scarpa S, Morrone S, Paradossi G, Frogley MD, Cinque G.

Sci Rep. 2019 Aug 14;9(1):11845. doi: 10.1038/s41598-019-48292-0.

4.

Granulicatella adiacens and Abiotrophia defectiva Native Vertebral Osteomyelitis: Three Cases and Literature Review of Clinical Characteristics and Treatment Approach.

Puzzolante C, Cuomo G, Meschiari M, Bedini A, Bonazza A, Venturelli C, Sarti M, Mussini C.

Case Rep Infect Dis. 2019 May 6;2019:5038563. doi: 10.1155/2019/5038563. eCollection 2019.

5.

Melatonin MT1 and MT2 Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle.

López-Canul M, Min SH, Posa L, De Gregorio D, Bedini A, Spadoni G, Gobbi G, Comai S.

Int J Mol Sci. 2019 May 17;20(10). pii: E2452. doi: 10.3390/ijms20102452.

6.

In vitro effects of 1-MHz ultrasound on the mitotic spindle.

Udroiu I, Coluzzi E, Bedini A, Giliberti C, Palomba R, Sgura A.

Environ Mol Mutagen. 2019 Aug;60(7):568-575. doi: 10.1002/em.22287. Epub 2019 Apr 3.

PMID:
30942920
7.

Long-term physical evolution of an elastomeric ultrasound contrast microbubble.

Domenici F, Brasili F, Oddo L, Cerroni B, Bedini A, Bordi F, Paradossi G.

J Colloid Interface Sci. 2019 Mar 22;540:185-196. doi: 10.1016/j.jcis.2018.12.110. Epub 2019 Jan 2.

PMID:
30640066
8.

Unraveling the Initial Plant Hormone Signaling, Metabolic Mechanisms and Plant Defense Triggering the Endomycorrhizal Symbiosis Behavior.

Bedini A, Mercy L, Schneider C, Franken P, Lucic-Mercy E.

Front Plant Sci. 2018 Dec 17;9:1800. doi: 10.3389/fpls.2018.01800. eCollection 2018. Review.

9.

Very low intensity ultrasounds as a new strategy to improve selective delivery of nanoparticles-complexes in cancer cells.

Loria R, Giliberti C, Bedini A, Palomba R, Caracciolo G, Ceci P, Falvo E, Marconi R, Falcioni R, Bossi G, Strigari L.

J Exp Clin Cancer Res. 2019 Jan 3;38(1):1. doi: 10.1186/s13046-018-1018-6.

10.

Design, Synthesis, and Biological Activity of Hydrogen Peroxide Responsive Arylboronate Melatonin Hybrids.

Bedini A, Fraternale A, Crinelli R, Mari M, Bartolucci S, Chiarantini L, Spadoni G.

Chem Res Toxicol. 2019 Jan 22;32(1):100-112. doi: 10.1021/acs.chemrestox.8b00216. Epub 2019 Jan 3.

PMID:
30560658
11.

Migration and health: A retrospective study about the prevalence of HBV, HIV, HCV, tuberculosis and syphilis infections amongst newly arrived migrants screened at the Infectious Diseases Unit of Modena, Italy.

Cuomo G, Franconi I, Riva N, Bianchi A, Digaetano M, Santoro A, Codeluppi M, Bedini A, Guaraldi G, Mussini C.

J Infect Public Health. 2019 Mar - Apr;12(2):200-204. doi: 10.1016/j.jiph.2018.10.004. Epub 2018 Oct 28.

12.

Identification of Bivalent Ligands with Melatonin Receptor Agonist and Fatty Acid Amide Hydrolase (FAAH) Inhibitory Activity That Exhibit Ocular Hypotensive Effect in the Rabbit.

Spadoni G, Bedini A, Furiassi L, Mari M, Mor M, Scalvini L, Lodola A, Ghidini A, Lucini V, Dugnani S, Scaglione F, Piomelli D, Jung KM, Supuran CT, Lucarini L, Durante M, Sgambellone S, Masini E, Rivara S.

J Med Chem. 2018 Sep 13;61(17):7902-7916. doi: 10.1021/acs.jmedchem.8b00893. Epub 2018 Sep 4.

PMID:
30126274
13.

DS-70, a novel and potent α4 integrin antagonist, is an effective treatment for experimental allergic conjunctivitis in guinea pigs.

Dattoli SD, Baiula M, De Marco R, Bedini A, Anselmi M, Gentilucci L, Spampinato S.

Br J Pharmacol. 2018 Oct;175(20):3891-3910. doi: 10.1111/bph.14458. Epub 2018 Sep 17.

14.

Constraining Endomorphin-1 by β,α-Hybrid Dipeptide/Heterocycle Scaffolds: Identification of a Novel κ-Opioid Receptor Selective Partial Agonist.

De Marco R, Bedini A, Spampinato S, Comellini L, Zhao J, Artali R, Gentilucci L.

J Med Chem. 2018 Jul 12;61(13):5751-5757. doi: 10.1021/acs.jmedchem.8b00296. Epub 2018 Jul 2.

PMID:
29901392
15.

Applications of low-cost sensing technologies for air quality monitoring and exposure assessment: How far have they gone?

Morawska L, Thai PK, Liu X, Asumadu-Sakyi A, Ayoko G, Bartonova A, Bedini A, Chai F, Christensen B, Dunbabin M, Gao J, Hagler GSW, Jayaratne R, Kumar P, Lau AKH, Louie PKK, Mazaheri M, Ning Z, Motta N, Mullins B, Rahman MM, Ristovski Z, Shafiei M, Tjondronegoro D, Westerdahl D, Williams R.

Environ Int. 2018 Jul;116:286-299. doi: 10.1016/j.envint.2018.04.018. Epub 2018 Apr 26. Review.

16.

Tetrahydroquinoline Ring as a Versatile Bioisostere of Tetralin for Melatonin Receptor Ligands.

Rivara S, Scalvini L, Lodola A, Mor M, Caignard DH, Delagrange P, Collina S, Lucini V, Scaglione F, Furiassi L, Mari M, Lucarini S, Bedini A, Spadoni G.

J Med Chem. 2018 Apr 26;61(8):3726-3737. doi: 10.1021/acs.jmedchem.8b00359. Epub 2018 Apr 4.

PMID:
29595267
17.

Differential effects on membrane permeability and viability of human keratinocyte cells undergoing very low intensity megasonic fields.

Domenici F, Brasili F, Giantulli S, Cerroni B, Bedini A, Giliberti C, Palomba R, Silvestri I, Morrone S, Paradossi G, Mattei M, Bordi F.

Sci Rep. 2017 Nov 28;7(1):16536. doi: 10.1038/s41598-017-16708-4.

18.

Antiproliferative and pro-apoptotic activity of melatonin analogues on melanoma and breast cancer cells.

Gatti G, Lucini V, Dugnani S, Calastretti A, Spadoni G, Bedini A, Rivara S, Mor M, Canti G, Scaglione F, Bevilacqua A.

Oncotarget. 2017 Aug 10;8(40):68338-68353. doi: 10.18632/oncotarget.20124. eCollection 2017 Sep 15.

19.

Genomic damage induced by 1-MHz ultrasound in vitro.

Udroiu I, Marinaccio J, Bedini A, Giliberti C, Palomba R, Sgura A.

Environ Mol Mutagen. 2018 Jan;59(1):60-68. doi: 10.1002/em.22124. Epub 2017 Aug 19.

PMID:
28833460
20.

Nociceptin/orphanin FQ antagonizes lipopolysaccharide-stimulated proliferation, migration and inflammatory signaling in human glioblastoma U87 cells.

Bedini A, Baiula M, Vincelli G, Formaggio F, Lombardi S, Caprini M, Spampinato S.

Biochem Pharmacol. 2017 Sep 15;140:89-104. doi: 10.1016/j.bcp.2017.05.021. Epub 2017 Jun 2.

PMID:
28583844
21.

Innovative Opioid Peptides and Biased Agonism: Novel Avenues for More Effective and Safer Analgesics to Treat Chronic Pain.

Bedini A, Spampinato S.

Curr Med Chem. 2018;25(32):3895-3916. doi: 10.2174/0929867324666170216095233. Review.

PMID:
28215164
22.

Next generation ultrasound platforms for theranostics.

Oddo L, Cerroni B, Domenici F, Bedini A, Bordi F, Chiessi E, Gerbes S, Paradossi G.

J Colloid Interface Sci. 2017 Apr 1;491:151-160. doi: 10.1016/j.jcis.2016.12.030. Epub 2016 Dec 18.

PMID:
28024192
23.

Clinical and Microbiological Characteristics of Visceral Leishmaniasis Outbreak in a Northern Italian Nonendemic Area: A Retrospective Observational Study.

Franceschini E, Puzzolante C, Menozzi M, Rossi L, Bedini A, Orlando G, Gennari W, Meacci M, Rugna G, Carra E, Codeluppi M, Mussini C.

Biomed Res Int. 2016;2016:6481028. doi: 10.1155/2016/6481028. Epub 2016 Nov 23.

24.

Versatile Picklocks To Access All Opioid Receptors: Tuning the Selectivity and Functional Profile of the Cyclotetrapeptide c[Phe-d-Pro-Phe-Trp] (CJ-15,208).

De Marco R, Bedini A, Spampinato S, Cavina L, Pirazzoli E, Gentilucci L.

J Med Chem. 2016 Oct 13;59(19):9255-9261. Epub 2016 Sep 22.

PMID:
27607020
25.

A Blocking Group Scan Using a Spherical Organometallic Complex Identifies an Unprecedented Binding Mode with Potent Activity In Vitro and In Vivo for the Opioid Peptide Dermorphin.

Strack M, Bedini A, Yip KT, Lombardi S, Siegmund D, Stoll R, Spampinato SM, Metzler-Nolte N.

Chemistry. 2016 Oct 4;22(41):14605-10. doi: 10.1002/chem.201602432. Epub 2016 Aug 24.

PMID:
27553294
26.

Antimicrobial stewardship in a Gastroenterology Department: Impact on antimicrobial consumption, antimicrobial resistance and clinical outcome.

Bedini A, De Maria N, Del Buono M, Bianchini M, Mancini M, Binda C, Brasacchio A, Orlando G, Franceschini E, Meschiari M, Sartini A, Zona S, Paioli S, Villa E, Gyssens IC, Mussini C.

Dig Liver Dis. 2016 Oct;48(10):1142-7. doi: 10.1016/j.dld.2016.06.023. Epub 2016 Jun 30.

PMID:
27453168
27.

Multidrug-resistant tuberculosis outbreak in an Italian prison: tolerance of pyrazinamide plus levofloxacin prophylaxis and serial interferon gamma release assays.

Bedini A, Garlassi E, Stentarelli C, Petrella S, Meacci M, Meccugni B, Meschiari M, Franceschini E, Cerri S, Brasacchio A, Rumpianesi F, Richeldi L, Mussini C.

New Microbes New Infect. 2016 Apr 7;12:45-51. doi: 10.1016/j.nmni.2016.03.010. eCollection 2016 Jul.

28.

Complex interfaces in "phase-change" contrast agents.

Capece S, Domenici F, Brasili F, Oddo L, Cerroni B, Bedini A, Bordi F, Chiessi E, Paradossi G.

Phys Chem Chem Phys. 2016 Mar 28;18(12):8378-88. doi: 10.1039/c5cp07538f.

PMID:
26931337
29.

Cardioprotective effects of fatty acid amide hydrolase inhibitor URB694, in a rodent model of trait anxiety.

Carnevali L, Vacondio F, Rossi S, Macchi E, Spadoni G, Bedini A, Neumann ID, Rivara S, Mor M, Sgoifo A.

Sci Rep. 2015 Dec 14;5:18218. doi: 10.1038/srep18218.

30.

Antidepressant-like activity and cardioprotective effects of fatty acid amide hydrolase inhibitor URB694 in socially stressed Wistar Kyoto rats.

Carnevali L, Vacondio F, Rossi S, Callegari S, Macchi E, Spadoni G, Bedini A, Rivara S, Mor M, Sgoifo A.

Eur Neuropsychopharmacol. 2015 Nov;25(11):2157-69. doi: 10.1016/j.euroneuro.2015.07.015. Epub 2015 Jul 29.

PMID:
26391492
31.

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines.

Spadoni G, Bedini A, Lucarini S, Mari M, Caignard DH, Boutin JA, Delagrange P, Lucini V, Scaglione F, Lodola A, Zanardi F, Pala D, Mor M, Rivara S.

J Med Chem. 2015 Sep 24;58(18):7512-25. doi: 10.1021/acs.jmedchem.5b01066.

PMID:
26334942
32.

Mu opioid receptor stimulation activates c-Jun N-terminal kinase 2 by distinct arrestin-dependent and independent mechanisms.

Kuhar JR, Bedini A, Melief EJ, Chiu YC, Striegel HN, Chavkin C.

Cell Signal. 2015 Sep;27(9):1799-806. doi: 10.1016/j.cellsig.2015.05.019. Epub 2015 Jun 5.

33.

Pharmacokinetic and pharmacodynamic evaluation of ramelteon : an insomnia therapy.

Spadoni G, Bedini A, Lucarini S, Mor M, Rivara S.

Expert Opin Drug Metab Toxicol. 2015 Jul;11(7):1145-56. doi: 10.1517/17425255.2015.1045487. Epub 2015 May 8. Review.

PMID:
25956235
34.

Global mapping of DNA conformational flexibility on Saccharomyces cerevisiae.

Menconi G, Bedini A, Barale R, Sbrana I.

PLoS Comput Biol. 2015 Apr 10;11(4):e1004136. doi: 10.1371/journal.pcbi.1004136. eCollection 2015 Apr.

35.

Role of nociceptin/orphanin FQ in thermoregulation.

Baiula M, Bedini A, Spampinato SM.

Neuropeptides. 2015 Apr;50:51-6. doi: 10.1016/j.npep.2015.03.005. Epub 2015 Mar 16. Review.

PMID:
25812480
36.

Iridium-catalyzed direct synthesis of tryptamine derivatives from indoles: exploiting n-protected β-amino alcohols as alkylating agents.

Bartolucci S, Mari M, Bedini A, Piersanti G, Spadoni G.

J Org Chem. 2015 Mar 20;80(6):3217-22. doi: 10.1021/acs.joc.5b00195. Epub 2015 Feb 26.

PMID:
25699684
37.

Selective melatonin MT2 receptor ligands relieve neuropathic pain through modulation of brainstem descending antinociceptive pathways.

Lopez-Canul M, Palazzo E, Dominguez-Lopez S, Luongo L, Lacoste B, Comai S, Angeloni D, Fraschini F, Boccella S, Spadoni G, Bedini A, Tarzia G, Maione S, Granados-Soto V, Gobbi G.

Pain. 2015 Feb;156(2):305-17. doi: 10.1097/01.j.pain.0000460311.71572.5f.

PMID:
25599452
38.

Therapeutic uses of melatonin and melatonin derivatives: a patent review (2012 - 2014).

Rivara S, Pala D, Bedini A, Spadoni G.

Expert Opin Ther Pat. 2015 Apr;25(4):425-41. doi: 10.1517/13543776.2014.1001739. Epub 2015 Jan 12. Review.

PMID:
25579320
39.

Potential genotoxic effects of low-intensity ultrasound on fibroblasts, evaluated with the cytokinesis-block micronucleus assay.

Udroiu I, Domenici F, Giliberti C, Bedini A, Palomba R, Luongo F, Pozzi D, Bordi F, Castellano AC.

Mutat Res Genet Toxicol Environ Mutagen. 2014 Sep 15;772:20-4. doi: 10.1016/j.mrgentox.2014.07.004. Epub 2014 Jul 25.

PMID:
25308543
40.

Cavitand-based solid-phase microextraction coating for the selective detection of nitroaromatic explosives in air and soil.

Bianchi F, Bedini A, Riboni N, Pinalli R, Gregori A, Sidisky L, Dalcanale E, Careri M.

Anal Chem. 2014 Nov 4;86(21):10646-52. doi: 10.1021/ac5025045. Epub 2014 Oct 24.

PMID:
25303228
41.
42.

Renilla luciferase reporter assay to study 3'UTR-driven posttranscriptional regulations of OPRM1.

Vincelli G, Bedini A.

Methods Mol Biol. 2015;1230:53-63. doi: 10.1007/978-1-4939-1708-2_4.

PMID:
25293315
43.

Synthesis and characterization of new bivalent agents as melatonin- and histamine H3-ligands.

Pala D, Scalvini L, Lodola A, Mor M, Flammini L, Barocelli E, Lucini V, Scaglione F, Bartolucci S, Bedini A, Rivara S, Spadoni G.

Int J Mol Sci. 2014 Sep 12;15(9):16114-33. doi: 10.3390/ijms150916114.

44.

In vitro activities of amphotericin B deoxycholate and liposomal amphotericin B against 604 clinical yeast isolates.

Montagna MT, Lovero G, Coretti C, De Giglio O, Martinelli D, Bedini A, Delia M, Rosato A, Codeluppi M, Caggiano G.

J Med Microbiol. 2014 Dec;63(Pt 12):1638-43. doi: 10.1099/jmm.0.075507-0. Epub 2014 Sep 10.

45.

Synthesis of tripeptides containing D-Trp substituted at the indole ring, assessment of opioid receptor binding and in vivo central antinociception.

De Marco R, Bedini A, Spampinato S, Gentilucci L.

J Med Chem. 2014 Aug 14;57(15):6861-6. doi: 10.1021/jm5002925. Epub 2014 Jul 30.

PMID:
25051243
46.

Mapracorat, a selective glucocorticoid receptor agonist, causes apoptosis of eosinophils infiltrating the conjunctiva in late-phase experimental ocular allergy.

Baiula M, Bedini A, Baldi J, Cavet ME, Govoni P, Spampinato S.

Drug Des Devel Ther. 2014 Jun 10;8:745-57. doi: 10.2147/DDDT.S62659. eCollection 2014.

47.

Towards the development of 5-HT₇ ligands combining serotonin-like and arylpiperazine moieties.

Spadoni G, Bedini A, Bartolucci S, Pala D, Mor M, Riccioni T, Borsini F, Cabri W, Celona D, Marzi M, Tarzia G, Rivara S, Minetti P.

Eur J Med Chem. 2014 Jun 10;80:8-35. doi: 10.1016/j.ejmech.2014.04.034. Epub 2014 Apr 13.

PMID:
24763360
48.

Does surgery improve survival of patients with malignant pleural mesothelioma?: a multicenter retrospective analysis of 1365 consecutive patients.

Bovolato P, Casadio C, Billè A, Ardissone F, Santambrogio L, Ratto GB, Garofalo G, Bedini AV, Garassino M, Porcu L, Torri V, Pastorino U.

J Thorac Oncol. 2014 Mar;9(3):390-6. doi: 10.1097/JTO.0000000000000064.

49.

Melatonin, selective and non-selective MT1/MT2 receptors agonists: differential effects on the 24-h vigilance states.

Ochoa-Sanchez R, Comai S, Spadoni G, Bedini A, Tarzia G, Gobbi G.

Neurosci Lett. 2014 Feb 21;561:156-61. doi: 10.1016/j.neulet.2013.12.069. Epub 2014 Jan 7.

PMID:
24406151
50.

Structural and permeability sensitivity of cells to low intensity ultrasound: Infrared and fluorescence evidence in vitro.

Domenici F, Giliberti C, Bedini A, Palomba R, Udroiu I, Di Giambattista L, Pozzi D, Morrone S, Bordi F, Congiu Castellano A.

Ultrasonics. 2014 Apr;54(4):1020-8. doi: 10.1016/j.ultras.2013.12.003. Epub 2013 Dec 14.

PMID:
24370376

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