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Items: 1 to 50 of 200

1.

Intra-Vitreal Administration of Microvesicles Derived from Human Adipose-Derived Multipotent Stromal Cells Improves Retinal Functionality in Dogs with Retinal Degeneration.

Cislo-Pakuluk A, Smieszek A, Kucharczyk N, Bedford PGC, Marycz K.

J Clin Med. 2019 Apr 13;8(4). pii: E510. doi: 10.3390/jcm8040510.

2.

Quality control guidelines for clinical-grade human induced pluripotent stem cell lines.

Sullivan S, Stacey GN, Akazawa C, Aoyama N, Baptista R, Bedford P, Bennaceur Griscelli A, Chandra A, Elwood N, Girard M, Kawamata S, Hanatani T, Latsis T, Lin S, Ludwig TE, Malygina T, Mack A, Mountford JC, Noggle S, Pereira LV, Price J, Sheldon M, Srivastava A, Stachelscheid H, Velayudhan SR, Ward NJ, Turner ML, Barry J, Song J.

Regen Med. 2018 Oct;13(7):859-866. doi: 10.2217/rme-2018-0095. Epub 2018 Sep 12.

3.

Considering Cell Therapy Product "Good Manufacturing Practice" Status.

Bedford P, Jy J, Collins L, Keizer S.

Front Med (Lausanne). 2018 Apr 30;5:118. doi: 10.3389/fmed.2018.00118. eCollection 2018. No abstract available.

4.

Research on Human Embryos and Reproductive Materials: Revisiting Canadian Law and Policy.

Ogbogu U, Zarzeczny A, Baltz J, Bedford P, Du J, Hyun I, Jaafar Y, Jurisicova A, Kleiderman E, Koukio Y, Knoppers BM, Leader A, Master Z, Nguyen MT, Noohi F, Ravitsky V, Toews M.

Healthc Policy. 2018 Feb;13(3):10-19. doi: 10.12927/hcpol.2018.25401.

5.

Human gene editing: revisiting Canadian policy.

Knoppers BM, Isasi R, Caulfield T, Kleiderman E, Bedford P, Illes J, Ogbogu U, Ravitsky V, Rudnicki M.

NPJ Regen Med. 2017 Jan 5;2:3. doi: 10.1038/s41536-017-0007-2. eCollection 2017. No abstract available.

6.

CRISPR Gene Editing Should Be Allowed in Canada, But Under What Circumstances?

Master Z, Bedford P.

J Obstet Gynaecol Can. 2018 Feb;40(2):224-226. doi: 10.1016/j.jogc.2017.08.028. Epub 2017 Oct 12. No abstract available.

PMID:
29032068
7.

Workshop to address gaps in regulation of minimally manipulated autologous cell therapies for homologous use in Canada.

Chisholm J, von Tigerstrom B, Bedford P, Fradette J, Viswanathan S.

Cytotherapy. 2017 Dec;19(12):1400-1411. doi: 10.1016/j.jcyt.2017.08.015. Epub 2017 Sep 28.

PMID:
28964743
8.

Achieving Efficient Manufacturing and Quality Assurance through Synthetic Cell Therapy Design.

Lipsitz YY, Bedford P, Davies AH, Timmins NE, Zandstra PW.

Cell Stem Cell. 2017 Jan 5;20(1):13-17. doi: 10.1016/j.stem.2016.12.003.

9.

Open-angle glaucoma in the Petit Basset Griffon Vendeen.

Bedford PG.

Vet Ophthalmol. 2017 Mar;20(2):98-102. doi: 10.1111/vop.12369. Epub 2016 Mar 4.

PMID:
26945802
10.

Mothering a Preterm Infant Receiving NIDCAP Care in a Level III Newborn Intensive Care Unit.

Nelson AM, Bedford PJ.

J Pediatr Nurs. 2016 Jul-Aug;31(4):e271-82. doi: 10.1016/j.pedn.2016.01.001. Epub 2016 Feb 13.

PMID:
26883058
11.

A Novel Genome-Wide Association Study Approach Using Genotyping by Exome Sequencing Leads to the Identification of a Primary Open Angle Glaucoma Associated Inversion Disrupting ADAMTS17.

Forman OP, Pettitt L, Komáromy AM, Bedford P, Mellersh C.

PLoS One. 2015 Dec 18;10(12):e0143546. doi: 10.1371/journal.pone.0143546. eCollection 2015.

12.

From the ophthalmoscope, bacon butties and Sunday shows to DNA technology for the diagnosis of hereditary ocular disease in the pedigree dog.

Bedford PG.

Vet J. 2015 Feb;203(2):138-40. doi: 10.1016/j.tvjl.2015.01.007. Epub 2015 Jan 13. No abstract available.

PMID:
25641550
13.

Can forensic pathologists diagnose pulmonary thromboembolism on postmortem computed tomography pulmonary angiography?

Burke MP, Bedford P, Baber Y.

Am J Forensic Med Pathol. 2014 Jun;35(2):124-31. doi: 10.1097/PAF.0000000000000086.

PMID:
24781394
14.

Post mortem sampling of the bladder for the identification of victims of fire related deaths.

Owen R, Bedford P, Leditschke J, Schlenker A, Hartman D.

Forensic Sci Int. 2013 Dec 10;233(1-3):14-20. doi: 10.1016/j.forsciint.2013.07.018. Epub 2013 Aug 2.

PMID:
24314496
15.

Pseudosubarachnoid hemorrhage on clinical computed tomography: the forensic implications of incorrect diagnosis.

Bedford P, O'Donnell C.

Am J Forensic Med Pathol. 2013 Jun;34(2):e4-6. doi: 10.1097/PAF.0b013e3182887565. No abstract available.

PMID:
23574873
16.

Different conditions and strategies to utilize forensic radiology in the cities of Melbourne, Australia and Berlin, Germany.

Bedford PJ, Oesterhelweg L.

Forensic Sci Med Pathol. 2013 Sep;9(3):321-6. doi: 10.1007/s12024-013-9424-8. Epub 2013 Mar 30.

PMID:
23543464
17.

The occurrence of cadaveric spasm is a myth.

Bedford PJ, Tsokos M.

Forensic Sci Med Pathol. 2013 Jun;9(2):244-8. doi: 10.1007/s12024-012-9391-5. Epub 2012 Nov 22. No abstract available.

PMID:
23179991
18.

Lot-to-lot consistency study of the fully liquid pentavalent DTwP-HepB-Hib vaccine Quinvaxem (®) demonstrating clinical equivalence, suitability of the vaccine as a booster and concomitant administration with measles vaccine.

Aspinall S, Traynor D, Bedford P, Hartmann K.

Hum Vaccin Immunother. 2012 Aug;8(8):1109-18. doi: 10.4161/hv.21095. Epub 2012 Aug 1. Erratum in: Hum Vaccin Immunother. 2013 Apr;9(4):937.

19.

Oral vitamin E absorption in English Cocker Spaniels with familial vitamin E deficiency and retinal pigment epithelial dystrophy.

McLellan GJ, Bedford PG.

Vet Ophthalmol. 2012 Sep;15 Suppl 2:48-56. doi: 10.1111/j.1463-5224.2012.01049.x. Epub 2012 Jul 25.

PMID:
22831287
20.

Routine CT scan combined with preliminary examination as a new method in determining the need for autopsy.

Bedford PJ.

Forensic Sci Med Pathol. 2012 Dec;8(4):390-4. doi: 10.1007/s12024-012-9349-7. Epub 2012 May 22.

PMID:
22615069
21.

Massive hemoperitoneum due to ruptured ectopic gestation: postmortem CT findings in a deeply frozen deceased person.

O'Donnell C, Bedford P, Burke M.

Leg Med (Tokyo). 2011 Sep;13(5):245-9. doi: 10.1016/j.legalmed.2011.05.006. Epub 2011 Aug 6.

PMID:
21821458
22.

Pattern of activin A and follistatin release in a sheep model of cardiopulmonary bypass.

Chen Y, Phillips DJ, McMillan J, Bedford P, Goldstein J, Wu H, Hedger MP, Smith JA.

Cytokine. 2011 May;54(2):154-60. doi: 10.1016/j.cyto.2011.01.001. Epub 2011 Feb 12.

PMID:
21320787
23.

2010 white paper on recent issues in regulated bioanalysis & global harmonization of bioanalytical guidance.

Savoie N, Garofolo F, van Amsterdam P, Bansal S, Beaver C, Bedford P, Booth BP, Evans C, Jemal M, Lefebvre M, Lopes de Silva AL, Lowes S, Marini JC, Massé R, Mawer L, Ormsby E, Rocci ML Jr, Viswanathan C, Wakelin-Smith J, Welink J, White JT, Woolf E.

Bioanalysis. 2010 Dec;2(12):1945-60. doi: 10.4155/bio.10.164.

24.

Retinal pigment epithelial dystrophy in the Briard.

Bedford PG.

Vet Rec. 2009 Mar 21;164(12):377. No abstract available.

PMID:
19305014
25.

Dendritic cells from control but not atopic donors respond to contact and respiratory sensitizer treatment in vitro with differential cytokine production and altered stimulatory capacity.

Holden NJ, Bedford PA, McCarthy NE, Marks NA, Ind PW, Jowsey IR, Basketter DA, Knight SC.

Clin Exp Allergy. 2008 Jul;38(7):1148-59. doi: 10.1111/j.1365-2222.2008.02997.x. Epub 2008 May 21.

PMID:
18498417
26.

Dendritic cells derived from bone marrow cells fail to acquire and present major histocompatibility complex antigens from other dendritic cells.

Bedford PA, Burke F, Stagg AJ, Knight SC.

Immunology. 2008 Aug;124(4):542-52. doi: 10.1111/j.1365-2567.2008.02808.x. Epub 2008 Feb 7.

27.

The fraction 1 and V protein antigens of Yersinia pestis activate dendritic cells to induce primary T cell responses.

Kingston R, Burke F, Robinson JH, Bedford PA, Jones SM, Knight SC, Williamson ED.

Clin Exp Immunol. 2007 Sep;149(3):561-9. Epub 2007 Jul 23.

28.

Exercise-induced serum enzyme elevations confounding the evaluation of investigational drug toxicity. Report of two cases in a vaccine trial.

Johnson C, Monath TP, Kanesa-Thasan N, Mathis D, Miller C, Shapiro S, Nichols R, McCarthy K, Deary A, Bedford P.

Hum Vaccin. 2005 Jan-Feb;1(1):24-9. Epub 2005 Jan 25.

PMID:
17038829
29.

Live attenuated chimeric yellow fever dengue type 2 (ChimeriVax-DEN2) vaccine: Phase I clinical trial for safety and immunogenicity: effect of yellow fever pre-immunity in induction of cross neutralizing antibody responses to all 4 dengue serotypes.

Guirakhoo F, Kitchener S, Morrison D, Forrat R, McCarthy K, Nichols R, Yoksan S, Duan X, Ermak TH, Kanesa-Thasan N, Bedford P, Lang J, Quentin-Millet MJ, Monath TP.

Hum Vaccin. 2006 Mar-Apr;2(2):60-7. Epub 2006 Mar 15.

PMID:
17012873
30.

Yellow fever 17D vaccine safety and immunogenicity in the elderly.

Monath TP, Cetron MS, McCarthy K, Nichols R, Archambault WT, Weld L, Bedford P.

Hum Vaccin. 2005 Sep-Oct;1(5):207-14. Epub 2005 Sep 2.

PMID:
17012867
31.

Adipose tissue of human omentum is a major source of dendritic cells, which lose MHC Class II and stimulatory function in Crohn's disease.

Bedford PA, Todorovic V, Westcott ED, Windsor AC, English NR, Al-Hassi HO, Raju KS, Mills S, Knight SC.

J Leukoc Biol. 2006 Sep;80(3):546-54. Epub 2006 Jul 5.

PMID:
16822853
32.

A live, attenuated recombinant West Nile virus vaccine.

Monath TP, Liu J, Kanesa-Thasan N, Myers GA, Nichols R, Deary A, McCarthy K, Johnson C, Ermak T, Shin S, Arroyo J, Guirakhoo F, Kennedy JS, Ennis FA, Green S, Bedford P.

Proc Natl Acad Sci U S A. 2006 Apr 25;103(17):6694-9. Epub 2006 Apr 14. Erratum in: Proc Natl Acad Sci U S A. 2006 Jul 11;103(28):10823.

33.

Three cases of activation of cutaneous squamous-cell carcinoma during treatment with prolonged administration of rituximab.

Fogarty GB, Bayne M, Bedford P, Bond R, Kannourakis G.

Clin Oncol (R Coll Radiol). 2006 Mar;18(2):155-6. No abstract available.

PMID:
16523821
34.

Comparative safety and immunogenicity of two attenuated enterotoxigenic Escherichia coli vaccine strains in healthy adults.

McKenzie R, Bourgeois AL, Engstrom F, Hall E, Chang HS, Gomes JG, Kyle JL, Cassels F, Turner AK, Randall R, Darsley M, Lee C, Bedford P, Shimko J, Sack DA.

Infect Immun. 2006 Feb;74(2):994-1000.

35.

Interleukin-4 can induce interleukin-4 production in dendritic cells.

Maroof A, Penny M, Kingston R, Murray C, Islam S, Bedford PA, Knight SC.

Immunology. 2006 Feb;117(2):271-9.

36.

Comparison of the antibody in lymphocyte supernatant (ALS) and ELISPOT assays for detection of mucosal immune responses to antigens of enterotoxigenic Escherichia coli in challenged and vaccinated volunteers.

Carpenter CM, Hall ER, Randall R, McKenzie R, Cassels F, Diaz N, Thomas N, Bedford P, Darsley M, Gewert C, Howard C, Sack RB, Sack DA, Chang HS, Gomes G, Bourgeois AL.

Vaccine. 2006 May 1;24(18):3709-18. Epub 2005 Jul 26.

PMID:
16153753
37.

Developing dendritic cells become 'lacy' cells packed with fat and glycogen.

Maroof A, English NR, Bedford PA, Gabrilovich DI, Knight SC.

Immunology. 2005 Aug;115(4):473-83.

38.

Randomized, double-blind, phase III, pivotal field trial of the comparative immunogenicity, safety, and tolerability of two yellow fever 17D vaccines (Arilvax and YF-VAX) in healthy infants and children in Peru.

Belmusto-Worn VE, Sanchez JL, McCarthy K, Nichols R, Bautista CT, Magill AJ, Pastor-Cauna G, Echevarria C, Laguna-Torres VA, Samame BK, Baldeon ME, Burans JP, Olson JG, Bedford P, Kitchener S, Monath TP.

Am J Trop Med Hyg. 2005 Feb;72(2):189-97.

PMID:
15741556
39.

Progressive retinal atrophy in dogs.

Bedford PG.

Vet Rec. 2005 Jan 22;156(4):124. No abstract available.

PMID:
15704559
40.

Thermoregulation during mild exercise at different circadian times.

Waterhouse J, Edwards B, Bedford P, Hughes A, Robinson K, Nevill A, Weinert D, Reilly T.

Chronobiol Int. 2004 Mar;21(2):253-75.

PMID:
15332346
41.

IL-10-producing B220+CD11c- APC in mouse spleen.

Burke F, Stagg AJ, Bedford PA, English N, Knight SC.

J Immunol. 2004 Aug 15;173(4):2362-72.

42.

Chimeric live, attenuated vaccine against Japanese encephalitis (ChimeriVax-JE): phase 2 clinical trials for safety and immunogenicity, effect of vaccine dose and schedule, and memory response to challenge with inactivated Japanese encephalitis antigen.

Monath TP, Guirakhoo F, Nichols R, Yoksan S, Schrader R, Murphy C, Blum P, Woodward S, McCarthy K, Mathis D, Johnson C, Bedford P.

J Infect Dis. 2003 Oct 15;188(8):1213-30. Epub 2003 Oct 3.

PMID:
14551893
43.

Clinical and pathological observations in English cocker spaniels with primary metabolic vitamin E deficiency and retinal pigment epithelial dystrophy.

McLellan GJ, Cappello R, Mayhew IG, Elks R, Lybaert P, Watté C, Bedford PG.

Vet Rec. 2003 Sep 6;153(10):287-92.

PMID:
14509574
44.

Vitamin E deficiency in dogs with retinal pigment epithelial dystrophy.

McLellan GJ, Elks R, Lybaert P, Watté C, Moore DL, Bedford PG.

Vet Rec. 2002 Nov 30;151(22):663-7.

PMID:
12498409
45.

Safety and efficacy of E coli enterotoxin adjuvant for urease-based rectal immunization against Helicobacter pylori.

Sougioultzis S, Lee CK, Alsahli M, Banerjee S, Cadoz M, Schrader R, Guy B, Bedford P, Monath TP, Kelly CP, Michetti P.

Vaccine. 2002 Dec 13;21(3-4):194-201.

PMID:
12450694
46.

Comparative safety and immunogenicity of two yellow fever 17D vaccines (ARILVAX and YF-VAX) in a phase III multicenter, double-blind clinical trial.

Monath TP, Nichols R, Archambault WT, Moore L, Marchesani R, Tian J, Shope RE, Thomas N, Schrader R, Furby D, Bedford P.

Am J Trop Med Hyg. 2002 May;66(5):533-41.

PMID:
12201587
47.

Dendritic cells, antigen distribution and the initiation of primary immune responses to self and non-self antigens.

Knight SC, Burke F, Bedford PA.

Semin Cancer Biol. 2002 Aug;12(4):301-8. Review.

PMID:
12147204
48.

Clinical proof of principle for ChimeriVax: recombinant live, attenuated vaccines against flavivirus infections.

Monath TP, McCarthy K, Bedford P, Johnson CT, Nichols R, Yoksan S, Marchesani R, Knauber M, Wells KH, Arroyo J, Guirakhoo F.

Vaccine. 2002 Jan 15;20(7-8):1004-18.

PMID:
11803060
49.

Interactions between dendritic cells.

Knight SC, Burke F, Bedford PA.

Adv Exp Med Biol. 2001;495:103-9. No abstract available.

PMID:
11774553
50.

Phase 2 clinical trial of attenuated Salmonella enterica serovar typhi oral live vector vaccine CVD 908-htrA in U.S. volunteers.

Tacket CO, Sztein MB, Wasserman SS, Losonsky G, Kotloff KL, Wyant TL, Nataro JP, Edelman R, Perry J, Bedford P, Brown D, Chatfield S, Dougan G, Levine MM.

Infect Immun. 2000 Mar;68(3):1196-201.

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