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Items: 23


Dynamic repression by BCL6 controls the genome-wide liver response to fasting and steatosis.

Sommars MA, Ramachandran K, Senagolage MD, Futtner CR, Germain DM, Allred AL, Omura Y, Bederman IR, Barish GD.

Elife. 2019 Apr 15;8. pii: e43922. doi: 10.7554/eLife.43922.


Loss of Transcriptional Repression by BCL6 Confers Insulin Sensitivity in the Setting of Obesity.

Senagolage MD, Sommars MA, Ramachandran K, Futtner CR, Omura Y, Allred AL, Wang J, Yang C, Procissi D, Evans RM, Han X, Bederman IR, Barish GD.

Cell Rep. 2018 Dec 18;25(12):3283-3298.e6. doi: 10.1016/j.celrep.2018.11.074.


Absence of leptin signaling allows fat accretion in cystic fibrosis mice.

Bederman IR, Pora G, O'Reilly M, Poleman J, Spoonhower K, Puchowicz M, Perez A, Erokwu BO, Rodriguez-Palacios A, Flask CA, Drumm ML.

Am J Physiol Gastrointest Liver Physiol. 2018 Nov 1;315(5):G685-G698. doi: 10.1152/ajpgi.00344.2017. Epub 2018 Aug 17.


Retinal Cholesterol Content Is Reduced in Simvastatin-Treated Mice Due to Inhibited Local Biosynthesis Albeit Increased Uptake of Serum Cholesterol.

Mast N, Bederman IR, Pikuleva IA.

Drug Metab Dispos. 2018 Nov;46(11):1528-1537. doi: 10.1124/dmd.118.083345. Epub 2018 Aug 16.


Conjugation of nitrated acetaminophen to Der p1 amplifies peripheral blood monocyte response to Der p1.

Thomas RG, Rivera Reyes BM, Gaston BM, Rivera Acosta NB, Bederman IR, Smith LA, Sutton MT, Wang B, Hunt JF, Bonfield TL.

PLoS One. 2017 Dec 11;12(12):e0188614. doi: 10.1371/journal.pone.0188614. eCollection 2017.


Pharmacokinetic Properties of Memantine after a Single Intraperitoneal Administration and Multiple Oral Doses in Euploid Mice and in the Ts65Dn Mouse Model of Down's Syndrome.

Victorino DB, Bederman IR, Costa ACS.

Basic Clin Pharmacol Toxicol. 2017 Nov;121(5):382-389. doi: 10.1111/bcpt.12816. Epub 2017 Jul 10.


Cholesterol in mouse retina originates primarily from in situ de novo biosynthesis.

Lin JB, Mast N, Bederman IR, Li Y, Brunengraber H, Björkhem I, Pikuleva IA.

J Lipid Res. 2016 Feb;57(2):258-64. doi: 10.1194/jlr.M064469. Epub 2015 Dec 2.


Chronic hindlimb suspension unloading markedly decreases turnover rates of skeletal and cardiac muscle proteins and adipose tissue triglycerides.

Bederman IR, Lai N, Shuster J, Henderson L, Ewart S, Cabrera ME.

J Appl Physiol (1985). 2015 Jul 1;119(1):16-26. doi: 10.1152/japplphysiol.00004.2014. Epub 2015 Apr 30.


Ventilatory pattern and energy expenditure are altered in cystic fibrosis mice.

Darrah RJ, Bederman IR, Mitchell AL, Hodges CA, Campanaro CK, Drumm ML, Jacono FJ.

J Cyst Fibros. 2013 Jul;12(4):345-51. doi: 10.1016/j.jcf.2012.11.008. Epub 2013 Jan 3.


Time course of hepatic gluconeogenesis during hindlimb suspension unloading.

Bederman IR, Chandramouli V, Sandlers Y, Henderson L, Cabrera ME.

Exp Physiol. 2013 Jan;98(1):278-89. doi: 10.1113/expphysiol.2012.067074. Epub 2012 Jun 15.


Triglyceride synthesis in epididymal adipose tissue: contribution of glucose and non-glucose carbon sources.

Bederman IR, Foy S, Chandramouli V, Alexander JC, Previs SF.

J Biol Chem. 2009 Mar 6;284(10):6101-8. doi: 10.1074/jbc.M808668200. Epub 2008 Dec 29.


Hormonal regulation of intracellular lipolysis in C57BL/6J mice: effect of diet-induced adiposity and data normalization.

Bederman IR, Previs SF.

Metabolism. 2008 Oct;57(10):1405-13. doi: 10.1016/j.metabol.2008.05.010.


Chronic ethanol and triglyceride turnover in white adipose tissue in rats: inhibition of the anti-lipolytic action of insulin after chronic ethanol contributes to increased triglyceride degradation.

Kang L, Chen X, Sebastian BM, Pratt BT, Bederman IR, Alexander JC, Previs SF, Nagy LE.

J Biol Chem. 2007 Sep 28;282(39):28465-73. Epub 2007 Aug 7.


Mice with a deletion in the gene for CCAAT/enhancer-binding protein beta are protected against diet-induced obesity.

Millward CA, Heaney JD, Sinasac DS, Chu EC, Bederman IR, Gilge DA, Previs SF, Croniger CM.

Diabetes. 2007 Jan;56(1):161-7.


Exposure to azide markedly decreases the abundance of mRNAs encoding cholesterol synthetic enzymes and inhibits cholesterol synthesis.

Kasturi S, Bederman IR, Christopher B, Previs SF, Ismail-Beigi F.

J Cell Biochem. 2007 Mar 1;100(4):1034-44.


Altered cholesterol homeostasis in cultured and in vivo models of cystic fibrosis.

White NM, Jiang D, Burgess JD, Bederman IR, Previs SF, Kelley TJ.

Am J Physiol Lung Cell Mol Physiol. 2007 Feb;292(2):L476-86. Epub 2006 Nov 3.


Reproducibility of gas chromatography-mass spectrometry measurements of 2H labeling of water: application for measuring body composition in mice.

McCabe BJ, Bederman IR, Croniger C, Millward C, Norment C, Previs SF.

Anal Biochem. 2006 Mar 15;350(2):171-6. Epub 2006 Jan 31.


Novel application of the "doubly labeled" water method: measuring CO2 production and the tissue-specific dynamics of lipid and protein in vivo.

Bederman IR, Dufner DA, Alexander JC, Previs SF.

Am J Physiol Endocrinol Metab. 2006 May;290(5):E1048-56. Epub 2005 Dec 20.


Using 2H2O to study the influence of feeding on protein synthesis: effect of isotope equilibration in vivo vs. in cell culture.

Dufner DA, Bederman IR, Brunengraber DZ, Rachdaoui N, Ismail-Beigi F, Siegfried BA, Kimball SR, Previs SF.

Am J Physiol Endocrinol Metab. 2005 Jun;288(6):E1277-83. Epub 2005 Jan 25.


In vitro modeling of fatty acid synthesis under conditions simulating the zonation of lipogenic [13C]acetyl-CoA enrichment in the liver.

Bederman IR, Kasumov T, Reszko AE, David F, Brunengraber H, Kelleher JK.

J Biol Chem. 2004 Oct 8;279(41):43217-26. Epub 2004 Jul 28.


Zonation of labeling of lipogenic acetyl-CoA across the liver: implications for studies of lipogenesis by mass isotopomer analysis.

Bederman IR, Reszko AE, Kasumov T, David F, Wasserman DH, Kelleher JK, Brunengraber H.

J Biol Chem. 2004 Oct 8;279(41):43207-16. Epub 2004 Jul 28.


Assay of the concentration and 13C-isotopic enrichment of malonyl-coenzyme A by gas chromatography-mass spectrometry.

Reszko AE, Kasumov T, Comte B, Pierce BA, David F, Bederman IR, Deutsch J, Des Rosiers C, Brunengraber H.

Anal Biochem. 2001 Nov 1;298(1):69-75.


Zonation of acetate labeling across the liver: implications for studies of lipogenesis by MIDA.

Puchowicz MA, Bederman IR, Comte B, Yang D, David F, Stone E, Jabbour K, Wasserman DH, Brunengraber H.

Am J Physiol. 1999 Dec;277(6):E1022-7. doi: 10.1152/ajpendo.1999.277.6.E1022.


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