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Items: 1 to 50 of 66

1.

Induction and migration of the anterior visceral endoderm is regulated by the extra-embryonic ectoderm.

Rodriguez TA, Srinivas S, Clements MP, Smith JC, Beddington RS.

Development. 2005 Jun;132(11):2513-20. Epub 2005 Apr 27.

2.

Targeted deletion of the novel cytoplasmic dynein mD2LIC disrupts the embryonic organiser, formation of the body axes and specification of ventral cell fates.

Rana AA, Barbera JP, Rodriguez TA, Lynch D, Hirst E, Smith JC, Beddington RS.

Development. 2004 Oct;131(20):4999-5007. Epub 2004 Sep 15.

3.

Dll3 pudgy mutation differentially disrupts dynamic expression of somite genes.

Kusumi K, Mimoto MS, Covello KL, Beddington RS, Krumlauf R, Dunwoodie SL.

Genesis. 2004 Jun;39(2):115-21.

PMID:
15170697
4.

Active cell migration drives the unilateral movements of the anterior visceral endoderm.

Srinivas S, Rodriguez T, Clements M, Smith JC, Beddington RS.

Development. 2004 Mar;131(5):1157-64.

5.

Hex homeobox gene-dependent tissue positioning is required for organogenesis of the ventral pancreas.

Bort R, Martinez-Barbera JP, Beddington RS, Zaret KS.

Development. 2004 Feb;131(4):797-806. Epub 2004 Jan 21.

6.

Cited1 is required in trophoblasts for placental development and for embryo growth and survival.

Rodriguez TA, Sparrow DB, Scott AN, Withington SL, Preis JI, Michalicek J, Clements M, Tsang TE, Shioda T, Beddington RS, Dunwoodie SL.

Mol Cell Biol. 2004 Jan;24(1):228-44.

7.

Characterizing embryonic gene expression patterns in the mouse using nonredundant sequence-based selection.

Sousa-Nunes R, Rana AA, Kettleborough R, Brickman JM, Clements M, Forrest A, Grimmond S, Avner P, Smith JC, Dunwoodie SL, Beddington RS.

Genome Res. 2003 Dec;13(12):2609-20. Epub 2003 Nov 12.

9.

Diverse requirements for Notch signalling in mammals.

Sparrow DB, Clements M, Withington SL, Scott AN, Novotny J, Sillence D, Kusumi K, Beddington RS, Dunwoodie SL.

Int J Dev Biol. 2002;46(4):365-74.

10.

Growth and early postimplantation defects in mice deficient for the bromodomain-containing protein Brd4.

Houzelstein D, Bullock SL, Lynch DE, Grigorieva EF, Wilson VA, Beddington RS.

Mol Cell Biol. 2002 Jun;22(11):3794-802.

11.
12.

Folic acid prevents exencephaly in Cited2 deficient mice.

Barbera JP, Rodriguez TA, Greene ND, Weninger WJ, Simeone A, Copp AJ, Beddington RS, Dunwoodie S.

Hum Mol Genet. 2002 Feb 1;11(3):283-93.

PMID:
11823447
13.

Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders.

Brickman JM, Clements M, Tyrell R, McNay D, Woods K, Warner J, Stewart A, Beddington RS, Dattani M.

Development. 2001 Dec;128(24):5189-99.

14.

The molecular phenotype of heparan sulfate in the Hs2st-/- mutant mouse.

Merry CL, Bullock SL, Swan DC, Backen AC, Lyon M, Beddington RS, Wilson VA, Gallagher JT.

J Biol Chem. 2001 Sep 21;276(38):35429-34. Epub 2001 Jul 16.

15.

Nodal signalling in the epiblast patterns the early mouse embryo.

Brennan J, Lu CC, Norris DP, Rodriguez TA, Beddington RS, Robertson EJ.

Nature. 2001 Jun 21;411(6840):965-9.

PMID:
11418863
16.

Distinct enhancer elements control Hex expression during gastrulation and early organogenesis.

Rodriguez TA, Casey ES, Harland RM, Smith JC, Beddington RS.

Dev Biol. 2001 Jun 15;234(2):304-16.

17.

Getting your head around Hex and Hesx1: forebrain formation in mouse.

Martinez-Barbera JP, Beddington RS.

Int J Dev Biol. 2001;45(1):327-36.

18.

Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia.

Thomas PQ, Dattani MT, Brickman JM, McNay D, Warne G, Zacharin M, Cameron F, Hurst J, Woods K, Dunger D, Stanhope R, Forrest S, Robinson IC, Beddington RS.

Hum Mol Genet. 2001 Jan 1;10(1):39-45.

PMID:
11136712
19.

Sp5, a new member of the Sp1 family, is dynamically expressed during development and genetically interacts with Brachyury.

Harrison SM, Houzelstein D, Dunwoodie SL, Beddington RS.

Dev Biol. 2000 Nov 15;227(2):358-72.

20.

Molecular genetics of septo-optic dysplasia.

Dattani ML, Martinez-Barbera J, Thomas PQ, Brickman JM, Gupta R, Wales JK, Hindmarsh PC, Beddington RS, Robinson IC.

Horm Res. 2000;53 Suppl 1:26-33. Review.

PMID:
10895039
21.

The homeobox gene Hesx1 is required in the anterior neural ectoderm for normal forebrain formation.

Martinez-Barbera JP, Rodriguez TA, Beddington RS.

Dev Biol. 2000 Jul 15;223(2):422-30.

22.

The homeobox gene Hex is required in definitive endodermal tissues for normal forebrain, liver and thyroid formation.

Martinez Barbera JP, Clements M, Thomas P, Rodriguez T, Meloy D, Kioussis D, Beddington RS.

Development. 2000 Jun;127(11):2433-45.

23.

Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function.

Brickman JM, Jones CM, Clements M, Smith JC, Beddington RS.

Development. 2000 Jun;127(11):2303-15.

24.

HESX1: a novel gene implicated in a familial form of septo-optic dysplasia.

Dattani MT, Martinez-Barbera JP, Thomas PQ, Brickman JM, Gupta R, Wales JK, Hindmarsh PC, Beddington RS, Robinson IC.

Acta Paediatr Suppl. 1999 Dec;88(433):49-54. Review.

PMID:
10626545
25.

Wnt signaling in Xenopus embryos inhibits bmp4 expression and activates neural development.

Baker JC, Beddington RS, Harland RM.

Genes Dev. 1999 Dec 1;13(23):3149-59.

26.

An anterior signalling centre in Xenopus revealed by the homeobox gene XHex.

Jones CM, Broadbent J, Thomas PQ, Smith JC, Beddington RS.

Curr Biol. 1999 Sep 9;9(17):946-54.

27.
28.

Axis development and early asymmetry in mammals.

Beddington RS, Robertson EJ.

Cell. 1999 Jan 22;96(2):195-209. Review. No abstract available.

29.

Isolation of developmentally regulated genes by differential display screening of cDNA libraries.

Gupta R, Thomas P, Beddington RS, Rigby PW.

Nucleic Acids Res. 1998 Oct 1;26(19):4538-9.

30.

Anterior patterning in mouse.

Beddington RS, Robertson EJ.

Trends Genet. 1998 Jul;14(7):277-84. Review.

PMID:
9676530
31.

Renal agenesis in mice homozygous for a gene trap mutation in the gene encoding heparan sulfate 2-sulfotransferase.

Bullock SL, Fletcher JM, Beddington RS, Wilson VA.

Genes Dev. 1998 Jun 15;12(12):1894-906.

32.

Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse.

Dattani MT, Martinez-Barbera JP, Thomas PQ, Brickman JM, Gupta R, Mårtensson IL, Toresson H, Fox M, Wales JK, Hindmarsh PC, Krauss S, Beddington RS, Robinson IC.

Nat Genet. 1998 Jun;19(2):125-33.

PMID:
9620767
33.
35.

T promoter activity in the absence of functional T protein during axis formation and elongation in the mouse.

Schmidt C, Wilson V, Stott D, Beddington RS.

Dev Biol. 1997 Sep 15;189(2):161-73.

36.
37.

Misexpression of Cwnt8C in the mouse induces an ectopic embryonic axis and causes a truncation of the anterior neuroectoderm.

Pöpperl H, Schmidt C, Wilson V, Hume CR, Dodd J, Krumlauf R, Beddington RS.

Development. 1997 Aug;124(15):2997-3005.

38.

Cbfa1, a candidate gene for cleidocranial dysplasia syndrome, is essential for osteoblast differentiation and bone development.

Otto F, Thornell AP, Crompton T, Denzel A, Gilmour KC, Rosewell IR, Stamp GW, Beddington RS, Mundlos S, Olsen BR, Selby PB, Owen MJ.

Cell. 1997 May 30;89(5):765-71.

39.

Axis duplication and anterior identity in the mouse embryo.

Thomas P, Brickman JM, Pöpperl H, Krumlauf R, Beddington RS.

Cold Spring Harb Symp Quant Biol. 1997;62:115-25. No abstract available.

PMID:
9598343
40.

BMP-7 influences pattern and growth of the developing hindbrain of mouse embryos.

Arkell R, Beddington RS.

Development. 1997 Jan;124(1):1-12.

41.

Genetic mapping and embryonic expression of a novel, maternally transcribed gene Mem3.

Hwang S, Benjamin LE, Oh B, Rothstein JL, Ackerman SL, Beddington RS, Solter D, Knowles BB.

Mamm Genome. 1996 Aug;7(8):586-90.

PMID:
8678978
42.

Cell fate and morphogenetic movement in the late mouse primitive streak.

Wilson V, Beddington RS.

Mech Dev. 1996 Mar;55(1):79-89.

43.

Isolation of novel tissue-specific genes from cDNA libraries representing the individual tissue constituents of the gastrulating mouse embryo.

Harrison SM, Dunwoodie SL, Arkell RM, Lehrach H, Beddington RS.

Development. 1995 Aug;121(8):2479-89.

44.

Capturing genes encoding membrane and secreted proteins important for mouse development.

Skarnes WC, Moss JE, Hurtley SM, Beddington RS.

Proc Natl Acad Sci U S A. 1995 Jul 3;92(14):6592-6.

45.

The T gene is necessary for normal mesodermal morphogenetic cell movements during gastrulation.

Wilson V, Manson L, Skarnes WC, Beddington RS.

Development. 1995 Mar;121(3):877-86.

47.

Induction of a second neural axis by the mouse node.

Beddington RS.

Development. 1994 Mar;120(3):613-20.

48.

Alterations in gene expression during mesoderm formation and axial patterning in Brachyury (T) embryos.

Rashbass P, Wilson V, Rosen B, Beddington RS.

Int J Dev Biol. 1994 Mar;38(1):35-44.

49.

Control of vertebrate gastrulation: inducing signals and responding genes.

Beddington RS, Smith JC.

Curr Opin Genet Dev. 1993 Aug;3(4):655-61. Review.

PMID:
8241775
50.

Quantitative analysis of protein synthesis in mouse embryos. II: Differentiation of endoderm, mesoderm, and ectoderm.

Latham KE, Beddington RS, Solter D, Garrels JI.

Mol Reprod Dev. 1993 Jun;35(2):140-50.

PMID:
8318219

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