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Influence of prediabetes on the effects of intensive systolic blood pressure control on kidney events.

Rathi N, Whelton PK, Chertow GM, Cushman WC, Cheung AK, Wei G, Boucher R, Kimmel PL, Bress A, Kramer HJ, Al-Marji C, Greene T, Beddhu S.

Am J Hypertens. 2019 Jun 29. pii: hpz105. doi: 10.1093/ajh/hpz105. [Epub ahead of print]


KDOQI US Commentary on the 2017 ACC/AHA Hypertension Guideline.

Kramer HJ, Townsend RR, Griffin K, Flynn JT, Weiner DE, Rocco MV, Choi MJ, Weir MR, Chang TI, Agarwal R, Beddhu S.

Am J Kidney Dis. 2019 Apr;73(4):437-458. doi: 10.1053/j.ajkd.2019.01.007.


Baseline living-donor kidney volume and function associate with 1-year post-nephrectomy kidney function.

Hall IE, Shaaban A, Wei G, Sikora MB, Bourija H, Beddhu S, Shihab F.

Clin Transplant. 2019 Mar;33(3):e13485. doi: 10.1111/ctr.13485. Epub 2019 Feb 12.


Use of Measures of Inflammation and Kidney Function for Prediction of Atherosclerotic Vascular Disease Events and Death in Patients With CKD: Findings From the CRIC Study.

Amdur RL, Feldman HI, Dominic EA, Anderson AH, Beddhu S, Rahman M, Wolf M, Reilly M, Ojo A, Townsend RR, Go AS, He J, Xie D, Thompson S, Budoff M, Kasner S, Kimmel PL, Kusek JW, Raj DS; CRIC Study Investigators.

Am J Kidney Dis. 2019 Mar;73(3):344-353. doi: 10.1053/j.ajkd.2018.09.012. Epub 2018 Dec 10.


Effects of Intensive Systolic Blood Pressure Lowering on Cardiovascular Events and Mortality in Patients With Type 2 Diabetes Mellitus on Standard Glycemic Control and in Those Without Diabetes Mellitus: Reconciling Results From ACCORD BP and SPRINT.

Beddhu S, Chertow GM, Greene T, Whelton PK, Ambrosius WT, Cheung AK, Cutler J, Fine L, Boucher R, Wei G, Zhang C, Kramer H, Bress AP, Kimmel PL, Oparil S, Lewis CE, Rahman M, Cushman WC.

J Am Heart Assoc. 2018 Sep 18;7(18):e009326. doi: 10.1161/JAHA.118.009326.


Pulse wave velocity and central aortic pressure in systolic blood pressure intervention trial participants.

Supiano MA, Lovato L, Ambrosius WT, Bates J, Beddhu S, Drawz P, Dwyer JP, Hamburg NM, Kitzman D, Lash J, Lustigova E, Miracle CM, Oparil S, Raj DS, Weiner DE, Taylor A, Vita JA, Yunis R, Chertow GM, Chonchol M.

PLoS One. 2018 Sep 26;13(9):e0203305. doi: 10.1371/journal.pone.0203305. eCollection 2018.


Self-reported Intentional Weight Loss and Risk of Death in Moderate Chronic Kidney Disease in the United States.

Bansal S, Wei G, Boucher RE, Beddhu S.

J Ren Nutr. 2018 Nov;28(6):422-427. doi: 10.1053/j.jrn.2018.04.001. Epub 2018 Aug 1.


Risk-benefit profile of intensive blood pressure treatment - Authors' reply.

Beddhu S, Greene T, Boucher R, Cushman WC, Wei G, Cheung AK, Whelton PK, Chertow GM.

Lancet Diabetes Endocrinol. 2018 Aug;6(8):602. doi: 10.1016/S2213-8587(18)30200-6. No abstract available.


Response by Beddhu et al to Letters Regarding Article, "Influence of Baseline Diastolic Blood Pressure on Effects of Intensive Compared With Standard Blood Pressure Control".

Beddhu S, Chertow GM, Cheung AK, Cushman WC, Greene T, Wei G, Boucher R, Whelton PK; SPRINT Research Group.

Circulation. 2018 Jun 12;137(24):2668-2669. doi: 10.1161/CIRCULATIONAHA.118.034738. No abstract available.


Adiponectin attenuates kidney injury and fibrosis in deoxycorticosterone acetate-salt and angiotensin II-induced CKD mice.

Tian M, Tang L, Wu Y, Beddhu S, Huang Y.

Am J Physiol Renal Physiol. 2018 Sep 1;315(3):F558-F571. doi: 10.1152/ajprenal.00137.2018. Epub 2018 Jun 6.


Impact of Intensive Versus Standard Blood Pressure Management by Tertiles of Blood Pressure in SPRINT (Systolic Blood Pressure Intervention Trial).

Shapiro BP, Ambrosius WT, Blackshear JL, Cushman WC, Whelton PK, Oparil S, Beddhu S, Dwyer JP, Gren LH, Kostis WJ, Lioudis M, Pisoni R, Rosendorff C, Haley WE; SPRINT Research Group*.

Hypertension. 2018 Jun;71(6):1064-1074. doi: 10.1161/HYPERTENSIONAHA.117.10646. Epub 2018 Apr 30.


Intensive systolic blood pressure control and incident chronic kidney disease in people with and without diabetes mellitus: secondary analyses of two randomised controlled trials.

Beddhu S, Greene T, Boucher R, Cushman WC, Wei G, Stoddard G, Ix JH, Chonchol M, Kramer H, Cheung AK, Kimmel PL, Whelton PK, Chertow GM.

Lancet Diabetes Endocrinol. 2018 Jul;6(7):555-563. doi: 10.1016/S2213-8587(18)30099-8. Epub 2018 Apr 21.


Apabetalone Mediated Epigenetic Modulation is Associated with Favorable Kidney Function and Alkaline Phosphatase Profile in Patients with Chronic Kidney Disease.

Kulikowski E, Halliday C, Johansson J, Sweeney M, Lebioda K, Wong N, Haarhaus M, Brandenburg V, Beddhu S, Tonelli M, Zoccali C, Kalantar-Zadeh K.

Kidney Blood Press Res. 2018;43(2):449-457. doi: 10.1159/000488257. Epub 2018 Mar 16.


Blood Pressure Measurement in SPRINT (Systolic Blood Pressure Intervention Trial).

Johnson KC, Whelton PK, Cushman WC, Cutler JA, Evans GW, Snyder JK, Ambrosius WT, Beddhu S, Cheung AK, Fine LJ, Lewis CE, Rahman M, Reboussin DM, Rocco MV, Oparil S, Wright JT Jr; SPRINT Research Group.

Hypertension. 2018 May;71(5):848-857. doi: 10.1161/HYPERTENSIONAHA.117.10479. Epub 2018 Mar 12.


Increasing Mortality in Adults With Diabetes and Low Estimated Glomerular Filtration Rate in the Absence of Albuminuria.

Kramer H, Boucher RE, Leehey D, Fried L, Wei G, Greene T, Rosas SE, Cooper R, Cao G, Beddhu S.

Diabetes Care. 2018 Apr;41(4):775-781. doi: 10.2337/dc17-1954. Epub 2018 Feb 7.


Associations of Dietary Protein and Energy Intakes With Protein-Energy Wasting Syndrome in Hemodialysis Patients.

Beddhu S, Wei G, Chen X, Boucher R, Kiani R, Raj D, Chonchol M, Greene T, Murtaugh MA.

Kidney Int Rep. 2017 Apr 18;2(5):821-830. doi: 10.1016/j.ekir.2017.04.002. eCollection 2017 Sep.


Effects of Intensive Blood Pressure Treatment on Acute Kidney Injury Events in the Systolic Blood Pressure Intervention Trial (SPRINT).

Rocco MV, Sink KM, Lovato LC, Wolfgram DF, Wiegmann TB, Wall BM, Umanath K, Rahbari-Oskoui F, Porter AC, Pisoni R, Lewis CE, Lewis JB, Lash JP, Katz LA, Hawfield AT, Haley WE, Freedman BI, Dwyer JP, Drawz PE, Dobre M, Cheung AK, Campbell RC, Bhatt U, Beddhu S, Kimmel PL, Reboussin DM, Chertow GM; SPRINT Research Group.

Am J Kidney Dis. 2018 Mar;71(3):352-361. doi: 10.1053/j.ajkd.2017.08.021. Epub 2017 Nov 20.


Association between Urine Ammonium and Urine TGF-β1 in CKD.

Raphael KL, Gilligan S, Hostetter TH, Greene T, Beddhu S.

Clin J Am Soc Nephrol. 2018 Feb 7;13(2):223-230. doi: 10.2215/CJN.07510717. Epub 2017 Nov 16.


Influence of Baseline Diastolic Blood Pressure on Effects of Intensive Compared With Standard Blood Pressure Control.

Beddhu S, Chertow GM, Cheung AK, Cushman WC, Rahman M, Greene T, Wei G, Campbell RC, Conroy M, Freedman BI, Haley W, Horwitz E, Kitzman D, Lash J, Papademetriou V, Pisoni R, Riessen E, Rosendorff C, Watnick SG, Whittle J, Whelton PK; SPRINT Research Group.

Circulation. 2018 Jan 9;137(2):134-143. doi: 10.1161/CIRCULATIONAHA.117.030848. Epub 2017 Oct 11.


Effects of Intensive Systolic Blood Pressure Control on Kidney and Cardiovascular Outcomes in Persons Without Kidney Disease: A Secondary Analysis of a Randomized Trial.

Beddhu S, Rocco MV, Toto R, Craven TE, Greene T, Bhatt U, Cheung AK, Cohen D, Freedman BI, Hawfield AT, Killeen AA, Kimmel PL, Lash J, Papademetriou V, Rahman M, Rastogi A, Servilla K, Townsend RR, Wall B, Whelton PK; SPRINT Research Group.

Ann Intern Med. 2017 Sep 19;167(6):375-383. doi: 10.7326/M16-2966. Epub 2017 Sep 5.


The association between insulin resistance and atrial fibrillation: A cross-sectional analysis from SPRINT (Systolic Blood Pressure Intervention Trial).

Cho ME, Craven TE, Cheung AK, Glasser SP, Rahman M, Soliman EZ, Stafford RS, Johnson KC, Bates JT, Burgner A, Taylor AA, Tamariz L, Tang R, Beddhu S; SPRINT Study Research Group.

J Clin Hypertens (Greenwich). 2017 Nov;19(11):1152-1161. doi: 10.1111/jch.13062. Epub 2017 Sep 3.


Associations of Protein-Energy Wasting Syndrome Criteria With Body Composition and Mortality in the General and Moderate Chronic Kidney Disease Populations in the United States.

Beddhu S, Chen X, Wei G, Raj D, Raphael KL, Boucher R, Chonchol MB, Murtaugh MA, Greene T.

Kidney Int Rep. 2017 May;2(3):390-399. doi: 10.1016/j.ekir.2017.01.002. Epub 2017 Jan 10.


Cost-Effectiveness of Intensive versus Standard Blood-Pressure Control.

Bress AP, Bellows BK, King JB, Hess R, Beddhu S, Zhang Z, Berlowitz DR, Conroy MB, Fine L, Oparil S, Morisky DE, Kazis LE, Ruiz-Negrón N, Powell J, Tamariz L, Whittle J, Wright JT Jr, Supiano MA, Cheung AK, Weintraub WS, Moran AE; SPRINT Research Group.

N Engl J Med. 2017 Aug 24;377(8):745-755. doi: 10.1056/NEJMsa1616035.


Effect of Intensive Versus Standard Blood Pressure Treatment According to Baseline Prediabetes Status: A Post Hoc Analysis of a Randomized Trial.

Bress AP, King JB, Kreider KE, Beddhu S, Simmons DL, Cheung AK, Zhang Y, Doumas M, Nord J, Sweeney ME, Taylor AA, Herring C, Kostis WJ, Powell J, Rastogi A, Roumie CL, Wiggers A, Williams JS, Yunis R, Zias A, Evans GW, Greene T, Rocco MV, Cushman WC, Reboussin DM, Feinglos MN, Papademetriou V; SPRINT Research Group.

Diabetes Care. 2017 Aug 9. pii: dc170885. doi: 10.2337/dc17-0885. [Epub ahead of print]


Effects of Intensive BP Control in CKD.

Cheung AK, Rahman M, Reboussin DM, Craven TE, Greene T, Kimmel PL, Cushman WC, Hawfield AT, Johnson KC, Lewis CE, Oparil S, Rocco MV, Sink KM, Whelton PK, Wright JT Jr, Basile J, Beddhu S, Bhatt U, Chang TI, Chertow GM, Chonchol M, Freedman BI, Haley W, Ix JH, Katz LA, Killeen AA, Papademetriou V, Ricardo AC, Servilla K, Wall B, Wolfgram D, Yee J; SPRINT Research Group.

J Am Soc Nephrol. 2017 Sep;28(9):2812-2823. doi: 10.1681/ASN.2017020148. Epub 2017 Jun 22.


Renal Replacement Therapy and Incremental Hemodialysis for Veterans with Advanced Chronic Kidney Disease.

Kalantar-Zadeh K, Crowley ST, Beddhu S, Chen JLT, Daugirdas JT, Goldfarb DS, Jin A, Kovesdy CP, Leehey DJ, Moradi H, Navaneethan SD, Norris KC, Obi Y, O'Hare A, Shafi T, Streja E, Unruh ML, Vachharajani TJ, Weisbord S, Rhee CM.

Semin Dial. 2017 May;30(3):251-261. doi: 10.1111/sdi.12601. Epub 2017 Apr 18. Review.


Urine Ammonium Predicts Clinical Outcomes in Hypertensive Kidney Disease.

Raphael KL, Carroll DJ, Murray J, Greene T, Beddhu S.

J Am Soc Nephrol. 2017 Aug;28(8):2483-2490. doi: 10.1681/ASN.2016101151. Epub 2017 Apr 6.


A Randomized Controlled Trial of the Effects of Febuxostat Therapy on Adipokines and Markers of Kidney Fibrosis in Asymptomatic Hyperuricemic Patients With Diabetic Nephropathy.

Beddhu S, Filipowicz R, Wang B, Wei G, Chen X, Roy AC, DuVall SL, Farrukh H, Habib AN, Bjordahl T, Simmons DL, Munger M, Stoddard G, Kohan DE, Greene T, Huang Y.

Can J Kidney Health Dis. 2016 Dec 5;3:2054358116675343. doi: 10.1177/2054358116675343. eCollection 2016.


Evaluation of the Effectiveness of a Patient-Centered Educational Mailer Designed to Improve Statin Adherence: A Pragmatic Trial.

Nord JW Jr, Berry A, Stults B, Burningham Z, Beddhu S.

EGEMS (Wash DC). 2017 Jan 23;4(1):1256. doi: 10.13063/2327-9214.1256. eCollection 2016.


Potential Deaths Averted and Serious Adverse Events Incurred From Adoption of the SPRINT (Systolic Blood Pressure Intervention Trial) Intensive Blood Pressure Regimen in the United States: Projections From NHANES (National Health and Nutrition Examination Survey).

Bress AP, Kramer H, Khatib R, Beddhu S, Cheung AK, Hess R, Bansal VK, Cao G, Yee J, Moran AE, Durazo-Arvizu R, Muntner P, Cooper RS.

Circulation. 2017 Apr 25;135(17):1617-1628. doi: 10.1161/CIRCULATIONAHA.116.025322. Epub 2017 Feb 13.


Effect of Intensive Blood Pressure Control on Gait Speed and Mobility Limitation in Adults 75 Years or Older: A Randomized Clinical Trial.

Odden MC, Peralta CA, Berlowitz DR, Johnson KC, Whittle J, Kitzman DW, Beddhu S, Nord JW, Papademetriou V, Williamson JD, Pajewski NM; Systolic Blood Pressure Intervention Trial (SPRINT) Research Group.

JAMA Intern Med. 2017 Apr 1;177(4):500-507. doi: 10.1001/jamainternmed.2016.9104.


Ambulatory Blood Pressure in Chronic Kidney Disease: Ready for Prime Time?

Velasquez MT, Beddhu S, Nobakht E, Rahman M, Raj DS.

Kidney Int Rep. 2016 Jul;1(2):94-104. doi: 10.1016/j.ekir.2016.05.001. Epub 2016 Jun 4.


Extracellular microRNA signature in chronic kidney disease.

Muralidharan J, Ramezani A, Hubal M, Knoblach S, Shrivastav S, Karandish S, Scott R, Maxwell N, Ozturk S, Beddhu S, Kopp JB, Raj DS.

Am J Physiol Renal Physiol. 2017 Jun 1;312(6):F982-F991. doi: 10.1152/ajprenal.00569.2016. Epub 2017 Jan 11.


Psoas Muscle Cross-sectional Area as a Measure of Whole-body Lean Muscle Mass in Maintenance Hemodialysis Patients.

Morrell GR, Ikizler TA, Chen X, Heilbrun ME, Wei G, Boucher R, Beddhu S.

J Ren Nutr. 2016 Jul;26(4):258-64. doi: 10.1053/j.jrn.2016.02.002. Epub 2016 Mar 16.


Chronic kidney disease, cerebral blood flow, and white matter volume in hypertensive adults.

Tamura MK, Pajewski NM, Bryan RN, Weiner DE, Diamond M, Van Buren P, Taylor A, Beddhu S, Rosendorff C, Jahanian H, Zaharchuk G; SPRINT Study Research Group.

Neurology. 2016 Mar 29;86(13):1208-16. doi: 10.1212/WNL.0000000000002527. Epub 2016 Feb 26.


Food for Thought: Diet as a Risk Factor for CKD.

Chen X, Beddhu S.

Am J Nephrol. 2015;42(6):425-6. doi: 10.1159/000443753. Epub 2016 Jan 21. No abstract available.


The Associations of Plant Protein Intake With All-Cause Mortality in CKD.

Chen X, Wei G, Jalili T, Metos J, Giri A, Cho ME, Boucher R, Greene T, Beddhu S.

Am J Kidney Dis. 2016 Mar;67(3):423-30. doi: 10.1053/j.ajkd.2015.10.018. Epub 2015 Dec 10.


Managing Hypertension in Patients with CKD: A Marathon, Not a SPRINT.

Chertow GM, Beddhu S, Lewis JB, Toto RD, Cheung AK.

J Am Soc Nephrol. 2016 Jan;27(1):40-3. doi: 10.1681/ASN.2015101125. Epub 2015 Nov 9.


Hypertension and Polypharmacy in Elderly Nursing Home Residents: When Less is More.

Raphael KL, Beddhu S.

Am J Kidney Dis. 2015 Oct;66(4):561-3. doi: 10.1053/j.ajkd.2015.06.012. Epub 2015 Jul 26. No abstract available.


Supervised oral protein supplementation during dialysis in patients with elevated C-reactive protein levels: a two phase, longitudinal, single center, open labeled study.

Beddhu S, Filipowicz R, Chen X, Neilson JL, Wei G, Huang Y, Greene T.

BMC Nephrol. 2015 Jun 23;16:87. doi: 10.1186/s12882-015-0070-0.


Light-intensity physical activities and mortality in the United States general population and CKD subpopulation.

Beddhu S, Wei G, Marcus RL, Chonchol M, Greene T.

Clin J Am Soc Nephrol. 2015 Jul 7;10(7):1145-53. doi: 10.2215/CJN.08410814. Epub 2015 Apr 30.


Low Physical Function in Maintenance Hemodialysis Patients Is Independent of Muscle Mass and Comorbidity.

Marcus RL, LaStayo PC, Ikizler TA, Wei G, Giri A, Chen X, Morrell G, Painter P, Beddhu S.

J Ren Nutr. 2015 Jul;25(4):371-5. doi: 10.1053/j.jrn.2015.01.020. Epub 2015 Mar 30.


Sedentary Behavior in Individuals With Diabetic Chronic Kidney Disease and Maintenance Hemodialysis.

Anderton N, Giri A, Wei G, Marcus RL, Chen X, Bjordahl T, Habib A, Herrera J, Beddhu S.

J Ren Nutr. 2015 Jul;25(4):364-70. doi: 10.1053/j.jrn.2015.01.018. Epub 2015 Mar 5.


Associations of body size and body composition with functional ability and quality of life in hemodialysis patients.

Martinson M, Ikizler TA, Morrell G, Wei G, Almeida N, Marcus RL, Filipowicz R, Greene TH, Beddhu S.

Clin J Am Soc Nephrol. 2014 Jun 6;9(6):1082-90. doi: 10.2215/CJN.09200913. Epub 2014 Apr 24.


Adiponectin retards the progression of diabetic nephropathy in db/db mice by counteracting angiotensin II.

Guo X, Zhou G, Guo M, Cheung AK, Huang Y, Beddhu S.

Physiol Rep. 2014 Feb 10;2(2):e00230. doi: 10.1002/phy2.230. eCollection 2014 Feb 1.


Improving CKD therapies and care: a National Dialogue.

Kaskel F, Batlle D, Beddhu S, Daugirdas J, Feldman H, Ferris M, Fine L, Freedman BI, Kimmel PL, Flessner MF, Star RA; Kidney Research National Dialogue (KRND).

Clin J Am Soc Nephrol. 2014 Apr;9(4):815-7. doi: 10.2215/CJN.12631213. Epub 2014 Feb 7.


Changes in anthropometry and mortality in maintenance hemodialysis patients in the HEMO Study.

Su CT, Yabes J, Pike F, Weiner DE, Beddhu S, Burrowes JD, Rocco MV, Unruh ML.

Am J Kidney Dis. 2013 Dec;62(6):1141-50. doi: 10.1053/j.ajkd.2013.05.015. Epub 2013 Jul 13.


Implications and importance of skeletal muscle mass in estimating glomerular filtration rate at dialysis initiation.

Zaman T, Filipowicz R, Beddhu S.

J Ren Nutr. 2013 May;23(3):233-6. doi: 10.1053/j.jrn.2013.01.028. Review.


Risk factor paradox in CKD and ESRD: does a healthy lifestyle matter?

Beddhu S, Abraham J.

Clin J Am Soc Nephrol. 2013 Apr;8(4):515-7. doi: 10.2215/CJN.02030213. Epub 2013 Mar 21. No abstract available.


Optimal nutrition for predialysis chronic kidney disease.

Filipowicz R, Beddhu S.

Adv Chronic Kidney Dis. 2013 Mar;20(2):175-80. doi: 10.1053/j.ackd.2012.12.007. Review.


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