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Items: 1 to 50 of 83

1.

Krt5+ Urothelial Cells are Developmental and Tissue Repair Progenitors in the Kidney.

Jackson AR, Hoff ML, Li B, Ching CB, McHugh KM, Becknell B.

Am J Physiol Renal Physiol. 2019 Jul 19. doi: 10.1152/ajprenal.00171.2019. [Epub ahead of print]

PMID:
31322419
2.

Ribonuclease 7 Shields the Kidney and Bladder from Invasive Uropathogenic Escherichia coli Infection.

Eichler T, Bender K, Murtha MJ, Schwartz L, Metheny J, Solden L, Jaggers RM, Bailey MT, Gupta S, Mosquera C, Ching C, La Perle K, Li B, Becknell B, Spencer JD.

J Am Soc Nephrol. 2019 Jun 25. pii: ASN.2018090929. doi: 10.1681/ASN.2018090929. [Epub ahead of print]

PMID:
31239387
3.

Innate immunity and urinary tract infection.

Ching C, Schwartz L, Spencer JD, Becknell B.

Pediatr Nephrol. 2019 Jun 13. doi: 10.1007/s00467-019-04269-9. [Epub ahead of print]

PMID:
31197473
4.

Analysis of the Ribonuclease A Superfamily of Antimicrobial Peptides in Patients Undergoing Chronic Peritoneal Dialysis.

Pottanat ND, Brook AC, Bartosova M, Cortado H, Gupta S, Li B, Jackson AR, Vonau M, Cohen S, Ferrara M, Ching CB, Spencer JD, Brauner A, Fraser DJ, Schmitt CP, Eberl M, Ayoob R, Becknell B.

Sci Rep. 2019 May 23;9(1):7753. doi: 10.1038/s41598-019-44219-x.

5.

Whole Transcriptome Analysis of Renal Intercalated Cells Predicts Lipopolysaccharide Mediated Inhibition of Retinoid X Receptor alpha Function.

Saxena V, Fitch J, Ketz J, White P, Wetzel A, Chanley MA, Spencer JD, Becknell B, Pierce KR, Arregui SW, Nelson RD, Schwartz GJ, Velazquez V, Walker LA, Chen X, Yan P, Hains DS, Schwaderer AL.

Sci Rep. 2019 Jan 24;9(1):545. doi: 10.1038/s41598-018-36921-z.

6.

Urinary Tract Infections.

Millner R, Becknell B.

Pediatr Clin North Am. 2019 Feb;66(1):1-13. doi: 10.1016/j.pcl.2018.08.002. Review.

PMID:
30454735
7.

Insulin receptor signaling regulates renal collecting duct and intercalated cell antibacterial defenses.

Murtha MJ, Eichler T, Bender K, Metheny J, Li B, Schwaderer AL, Mosquera C, James C, Schwartz L, Becknell B, Spencer JD.

J Clin Invest. 2018 Dec 3;128(12):5634-5646. doi: 10.1172/JCI98595. Epub 2018 Nov 12.

8.

Common clinical markers predict end-stage renal disease in children with obstructive uropathy.

McLeod DJ, Ching CB, Sebastião YV, Greenberg JH, Furth SL, McHugh KM, Becknell B.

Pediatr Nephrol. 2019 Mar;34(3):443-448. doi: 10.1007/s00467-018-4107-z. Epub 2018 Oct 13.

9.

Novel role for androgen signaling in pyelonephritis.

Ching CB, Becknell B.

Kidney Int. 2018 Sep;94(3):455-457. doi: 10.1016/j.kint.2018.05.020.

PMID:
30143065
10.

The uroplakin plaque promotes renal structural integrity during congenital and acquired urinary tract obstruction.

Jackson AR, Li B, Cohen SH, Ching CB, McHugh KM, Becknell B.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F1019-F1031. doi: 10.1152/ajprenal.00173.2018. Epub 2018 Jun 13.

PMID:
29897287
11.

Urinary antimicrobial peptides: Potential novel biomarkers of obstructive uropathy.

Gupta S, Jackson AR, DaJusta DG, McLeod DJ, Alpert SA, Jayanthi VR, McHugh K, Schwaderer AR, Becknell B, Ching CB.

J Pediatr Urol. 2018 Jun;14(3):238.e1-238.e6. doi: 10.1016/j.jpurol.2018.03.006. Epub 2018 Mar 29.

PMID:
29706289
12.

Interleukin-6/Stat3 signaling has an essential role in the host antimicrobial response to urinary tract infection.

Ching CB, Gupta S, Li B, Cortado H, Mayne N, Jackson AR, McHugh KM, Becknell B.

Kidney Int. 2018 Jun;93(6):1320-1329. doi: 10.1016/j.kint.2017.12.006. Epub 2018 Feb 21.

13.

X-Linked Glomerulopathy Due to COL4A5 Founder Variant.

Barua M, John R, Stella L, Li W, Roslin NM, Sharif B, Hack S, Lajoie-Starkell G, Schwaderer AL, Becknell B, Wuttke M, Köttgen A, Cattran D, Paterson AD, Pei Y.

Am J Kidney Dis. 2018 Mar;71(3):441-445. doi: 10.1053/j.ajkd.2017.09.005. Epub 2017 Dec 1.

PMID:
29198386
14.

Cell-specific qRT-PCR of renal epithelial cells reveals a novel innate immune signature in murine collecting duct.

Saxena V, Hains DS, Ketz J, Chanley M, Spencer JD, Becknell B, Pierce KR, Nelson RD, Purkerson JM, Schwartz GJ, Schwaderer AL.

Am J Physiol Renal Physiol. 2018 Oct 1;315(4):F812-F823. doi: 10.1152/ajprenal.00512.2016. Epub 2017 May 3.

PMID:
28468965
15.

Inflammation drives renal scarring in experimental pyelonephritis.

Li B, Haridas B, Jackson AR, Cortado H, Mayne N, Kohnken R, Bolon B, McHugh KM, Schwaderer AL, Spencer JD, Ching CB, Hains DS, Justice SS, Partida-Sanchez S, Becknell B.

Am J Physiol Renal Physiol. 2017 Jan 1;312(1):F43-F53. doi: 10.1152/ajprenal.00471.2016. Epub 2016 Oct 19.

16.

Insulin and the phosphatidylinositol 3-kinase signaling pathway regulate Ribonuclease 7 expression in the human urinary tract.

Eichler TE, Becknell B, Easterling RS, Ingraham SE, Cohen DM, Schwaderer AL, Hains DS, Li B, Cohen A, Metheny J, Tridandapani S, Spencer JD.

Kidney Int. 2016 Sep;90(3):568-79. doi: 10.1016/j.kint.2016.04.025. Epub 2016 Jul 9.

17.

Renal epithelial miR-205 expression correlates with disease severity in a mouse model of congenital obstructive nephropathy.

Wilhide ME, Feller JD, Li B, Mohamed AZ, Becknell B, Jackson AR, McHugh KM, Ingraham SE.

Pediatr Res. 2016 Oct;80(4):602-9. doi: 10.1038/pr.2016.121. Epub 2016 Jun 7.

18.

Uroepithelial thickening improves detection of vesicoureteral reflux in infants with prenatal hydronephrosis.

Gordon ZN, McLeod DJ, Ching CB, Herz DB, Bates DG, Becknell B, Alpert SA.

J Pediatr Urol. 2016 Aug;12(4):257.e1-7. doi: 10.1016/j.jpurol.2016.04.018. Epub 2016 May 27.

19.

A Review of Ribonuclease 7's Structure, Regulation, and Contributions to Host Defense.

Becknell B, Spencer JD.

Int J Mol Sci. 2016 Mar 22;17(3):423. doi: 10.3390/ijms17030423. Review.

20.

Polymorphisms in α-Defensin-Encoding DEFA1A3 Associate with Urinary Tract Infection Risk in Children with Vesicoureteral Reflux.

Schwaderer AL, Wang H, Kim S, Kline JM, Liang D, Brophy PD, McHugh KM, Tseng GC, Saxena V, Barr-Beare E, Pierce KR, Shaikh N, Manak JR, Cohen DM, Becknell B, Spencer JD, Baker PB, Yu CY, Hains DS.

J Am Soc Nephrol. 2016 Oct;27(10):3175-3186. Epub 2016 Mar 3.

21.

Baclofen Toxicity Responsive to Hemodialysis in a Pediatric Patient with Acute Kidney Injury.

Gee SW, Outsen S, Becknell B, Schwaderer AL.

J Pediatr Intensive Care. 2016 Mar;5(1):37-40. doi: 10.1055/s-0035-1568151. Epub 2015 Nov 21.

22.

Expression and Significance of the HIP/PAP and RegIIIγ Antimicrobial Peptides during Mammalian Urinary Tract Infection.

Spencer JD, Jackson AR, Li B, Ching CB, Vonau M, Easterling RS, Schwaderer AL, McHugh KM, Becknell B.

PLoS One. 2015 Dec 10;10(12):e0144024. doi: 10.1371/journal.pone.0144024. eCollection 2015.

23.

The Interaction between Enterobacteriaceae and Calcium Oxalate Deposits.

Barr-Beare E, Saxena V, Hilt EE, Thomas-White K, Schober M, Li B, Becknell B, Hains DS, Wolfe AJ, Schwaderer AL.

PLoS One. 2015 Oct 8;10(10):e0139575. doi: 10.1371/journal.pone.0139575. eCollection 2015.

24.

Urine Stasis Predisposes to Urinary Tract Infection by an Opportunistic Uropathogen in the Megabladder (Mgb) Mouse.

Becknell B, Mohamed AZ, Li B, Wilhide ME, Ingraham SE.

PLoS One. 2015 Sep 24;10(9):e0139077. doi: 10.1371/journal.pone.0139077. eCollection 2015.

25.

Amplifying renal immunity: the role of antimicrobial peptides in pyelonephritis.

Becknell B, Schwaderer A, Hains DS, Spencer JD.

Nat Rev Nephrol. 2015 Nov;11(11):642-55. doi: 10.1038/nrneph.2015.105. Epub 2015 Jul 7. Review.

PMID:
26149835
26.

Uroepithelial Thickening on Sonography Improves Detection of Vesicoureteral Reflux in Children with First Febrile Urinary Tract Infection.

Gordon ZN, McLeod DJ, Becknell B, Bates DG, Alpert SA.

J Urol. 2015 Oct;194(4):1074-9. doi: 10.1016/j.juro.2015.05.001. Epub 2015 May 9.

PMID:
25963184
27.

Trends in pediatric urolithiasis: patient characteristics, associated diagnoses, and financial burden.

Kusumi K, Becknell B, Schwaderer A.

Pediatr Nephrol. 2015 May;30(5):805-10. doi: 10.1007/s00467-014-3012-3. Epub 2014 Dec 7.

PMID:
25481020
28.

The diagnosis, evaluation and treatment of acute and recurrent pediatric urinary tract infections.

Becknell B, Schober M, Korbel L, Spencer JD.

Expert Rev Anti Infect Ther. 2015 Jan;13(1):81-90. doi: 10.1586/14787210.2015.986097. Epub 2014 Nov 25. Review.

29.

Hemodialysis for near-fatal sodium phosphate toxicity in a child receiving sodium phosphate enemas.

Becknell B, Smoyer WE, O'Brien NF.

Pediatr Emerg Care. 2014 Nov;30(11):814-7. doi: 10.1097/PEC.0000000000000267.

PMID:
25373567
30.

Bacterial differentiation, development, and disease: mechanisms for survival.

Justice SS, Harrison A, Becknell B, Mason KM.

FEMS Microbiol Lett. 2014 Nov;360(1):1-8. doi: 10.1111/1574-6968.12602. Epub 2014 Oct 1. Review.

31.

Carbonic anhydrase 2 deficiency leads to increased pyelonephritis susceptibility.

Hains DS, Chen X, Saxena V, Barr-Beare E, Flemming W, Easterling R, Becknell B, Schwartz GJ, Schwaderer AL.

Am J Physiol Renal Physiol. 2014 Oct 1;307(7):F869-80. doi: 10.1152/ajprenal.00344.2014. Epub 2014 Aug 20.

32.

Ribonucleases 6 and 7 have antimicrobial function in the human and murine urinary tract.

Becknell B, Eichler TE, Beceiro S, Li B, Easterling RS, Carpenter AR, James CL, McHugh KM, Hains DS, Partida-Sanchez S, Spencer JD.

Kidney Int. 2015 Jan;87(1):151-61. doi: 10.1038/ki.2014.268. Epub 2014 Jul 30.

33.

Expression and antimicrobial function of beta-defensin 1 in the lower urinary tract.

Becknell B, Spencer JD, Carpenter AR, Chen X, Singh A, Ploeger S, Kline J, Ellsworth P, Li B, Proksch E, Schwaderer AL, Hains DS, Justice SS, McHugh KM.

PLoS One. 2013 Oct 21;8(10):e77714. doi: 10.1371/journal.pone.0077714. eCollection 2013.

34.

Molecular basis of renal adaptation in a murine model of congenital obstructive nephropathy.

Becknell B, Carpenter AR, Allen JL, Wilhide ME, Ingraham SE, Hains DS, McHugh KM.

PLoS One. 2013 Sep 4;8(9):e72762. doi: 10.1371/journal.pone.0072762. eCollection 2013.

35.

The innate immune response during urinary tract infection and pyelonephritis.

Spencer JD, Schwaderer AL, Becknell B, Watson J, Hains DS.

Pediatr Nephrol. 2014 Jul;29(7):1139-49. doi: 10.1007/s00467-013-2513-9. Epub 2013 Jun 5. Review.

36.

Struvite urolithiasis and chronic urinary tract infection in a murine model of urinary diversion.

Becknell B, Carpenter AR, Bolon B, Asplin JR, Ingraham SE, Hains DS, Schwaderer AL, McHugh KM.

Urology. 2013 May;81(5):943-8. doi: 10.1016/j.urology.2013.02.003. Epub 2013 Mar 20.

37.

Crucial roles of the protein kinases MK2 and MK3 in a mouse model of glomerulonephritis.

Guess AJ, Ayoob R, Chanley M, Manley J, Cajaiba MM, Agrawal S, Pengal R, Pyle AL, Becknell B, Kopp JB, Ronkina N, Gaestel M, Benndorf R, Smoyer WE.

PLoS One. 2013;8(1):e54239. doi: 10.1371/journal.pone.0054239. Epub 2013 Jan 23.

38.

A new 'tac' for childhood nephrotic syndrome.

Becknell B, Greenbaum LA, Smoyer WE.

Kidney Int. 2012 Nov;82(10):1049-51. doi: 10.1038/ki.2012.272.

39.

Ultrasound imaging of the murine kidney.

Carpenter AR, Becknell B, Ingraham SE, McHugh KM.

Methods Mol Biol. 2012;886:403-10. doi: 10.1007/978-1-61779-851-1_35.

PMID:
22639280
40.

Urinary diversion via cutaneous vesicostomy in the megabladder mouse.

Carpenter AR, Becknell B, Hirselj DA, McHugh KM.

Methods Mol Biol. 2012;886:393-402. doi: 10.1007/978-1-61779-851-1_34.

PMID:
22639279
41.

Human alpha defensin 5 expression in the human kidney and urinary tract.

Spencer JD, Hains DS, Porter E, Bevins CL, DiRosario J, Becknell B, Wang H, Schwaderer AL.

PLoS One. 2012;7(2):e31712. doi: 10.1371/journal.pone.0031712. Epub 2012 Feb 16.

42.

Impact of urinary tract infection on inpatient healthcare for congenital obstructive uropathy.

Becknell B, Hains DS, Schwaderer AL, Vanderbrink BA, Spencer JD, Reagan PB, McHugh KM.

J Pediatr Urol. 2012 Oct;8(5):470-6. doi: 10.1016/j.jpurol.2011.10.021. Epub 2011 Nov 25.

PMID:
22119410
43.

Hepatoblastoma and prune belly syndrome: a potential association.

Becknell B, Pais P, Onimoe G, Rangarajan H, Schwaderer AL, McHugh K, Ranalli MA, Hains DS.

Pediatr Nephrol. 2011 Aug;26(8):1269-73. doi: 10.1007/s00467-011-1874-1. Epub 2011 May 20.

PMID:
21597971
44.

The demographics and costs of inpatient vesicoureteral reflux management in the USA.

Spencer JD, Schwaderer A, McHugh K, Vanderbrink B, Becknell B, Hains DS.

Pediatr Nephrol. 2011 Nov;26(11):1995-2001. doi: 10.1007/s00467-011-1900-3. Epub 2011 May 10.

PMID:
21556713
45.

PRDM1/Blimp-1 controls effector cytokine production in human NK cells.

Smith MA, Maurin M, Cho HI, Becknell B, Freud AG, Yu J, Wei S, Djeu J, Celis E, Caligiuri MA, Wright KL.

J Immunol. 2010 Nov 15;185(10):6058-67. doi: 10.4049/jimmunol.1001682. Epub 2010 Oct 13.

46.

Novel X-linked glomerulopathy is associated with a COL4A5 missense mutation in a non-collagenous interruption.

Becknell B, Zender GA, Houston R, Baker PB, McBride KL, Luo W, Hains DS, Borza DB, Schwaderer AL.

Kidney Int. 2011 Jan;79(1):120-7. doi: 10.1038/ki.2010.354. Epub 2010 Sep 29.

47.

Interleukin-1beta selectively expands and sustains interleukin-22+ immature human natural killer cells in secondary lymphoid tissue.

Hughes T, Becknell B, Freud AG, McClory S, Briercheck E, Yu J, Mao C, Giovenzana C, Nuovo G, Wei L, Zhang X, Gavrilin MA, Wewers MD, Caligiuri MA.

Immunity. 2010 Jun 25;32(6):803-14. doi: 10.1016/j.immuni.2010.06.007.

48.

The PD-1/PD-L1 axis modulates the natural killer cell versus multiple myeloma effect: a therapeutic target for CT-011, a novel monoclonal anti-PD-1 antibody.

Benson DM Jr, Bakan CE, Mishra A, Hofmeister CC, Efebera Y, Becknell B, Baiocchi RA, Zhang J, Yu J, Smith MK, Greenfield CN, Porcu P, Devine SM, Rotem-Yehudar R, Lozanski G, Byrd JC, Caligiuri MA.

Blood. 2010 Sep 30;116(13):2286-94. doi: 10.1182/blood-2010-02-271874. Epub 2010 May 11.

49.

Modulation of SOCS protein expression influences the interferon responsiveness of human melanoma cells.

Lesinski GB, Zimmerer JM, Kreiner M, Trefry J, Bill MA, Young GS, Becknell B, Carson WE 3rd.

BMC Cancer. 2010 Apr 14;10:142. doi: 10.1186/1471-2407-10-142.

50.

Deletion of Frs2alpha from the ureteric epithelium causes renal hypoplasia.

Sims-Lucas S, Cullen-McEwen L, Eswarakumar VP, Hains D, Kish K, Becknell B, Zhang J, Bertram JF, Wang F, Bates CM.

Am J Physiol Renal Physiol. 2009 Nov;297(5):F1208-19. doi: 10.1152/ajprenal.00262.2009. Epub 2009 Sep 9.

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