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Items: 1 to 50 of 349

1.

Benefit evaluation in multiple sclerosis relapse treatment from the patients' perspective - Development and validation of a new questionnaire.

Beckmann H, Augustin M, Heesen C, Poettgen J, Blome C.

Mult Scler Relat Disord. 2019 Feb;28:256-261. doi: 10.1016/j.msard.2018.12.021. Epub 2018 Dec 17.

PMID:
30639826
2.

A single class of ARF GTPase activated by several pathway-specific ARF-GEFs regulates essential membrane traffic in Arabidopsis.

Singh MK, Richter S, Beckmann H, Kientz M, Stierhof YD, Anders N, Fäßler F, Nielsen M, Knöll C, Thomann A, Franz-Wachtel M, Macek B, Skriver K, Pimpl P, Jürgens G.

PLoS Genet. 2018 Nov 15;14(11):e1007795. doi: 10.1371/journal.pgen.1007795. eCollection 2018 Nov.

3.

Understanding and Predicting Antidepressant Response: Using Animal Models to Move Toward Precision Psychiatry.

Herzog DP, Beckmann H, Lieb K, Ryu S, Müller MB.

Front Psychiatry. 2018 Oct 22;9:512. doi: 10.3389/fpsyt.2018.00512. eCollection 2018. Review.

4.

Objective assessment of gait and posture in premanifest and manifest Huntington disease - A multi-center study.

Beckmann H, Bohlen S, Saft C, Hoffmann R, Gerss J, Muratori L, Ringelstein EB, Landwehrmeyer GB, Reilmann R.

Gait Posture. 2018 May;62:451-457. doi: 10.1016/j.gaitpost.2018.03.039. Epub 2018 Apr 7.

PMID:
29660633
5.

A benzothiadiazine derivative and methylprednisolone are novel and selective activators of transient receptor potential canonical 5 (TRPC5) channels.

Beckmann H, Richter J, Hill K, Urban N, Lemoine H, Schaefer M.

Cell Calcium. 2017 Sep;66:10-18. doi: 10.1016/j.ceca.2017.05.012. Epub 2017 Jun 2.

PMID:
28807145
6.

Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses.

D'Souza WN, Douangpanya J, Mu S, Jaeckel P, Zhang M, Maxwell JR, Rottman JB, Labitzke K, Willee A, Beckmann H, Wang Y, Li Y, Schwandner R, Johnston JA, Towne JE, Hsu H.

PLoS One. 2017 Jul 20;12(7):e0180190. doi: 10.1371/journal.pone.0180190. eCollection 2017.

7.

Efficacy of standard prophylaxis versus on-demand treatment with bayer's sucrose-formulated recombinant FVIII (rFVIII-FS) in Chinese children with severe hemophilia A.

Zhao Y, Xiao J, Yang R, Wu R, Hu Y, Beckmann H, Wu J, Hou Q, Sun J.

Pediatr Hematol Oncol. 2017 Apr;34(3):138-148. doi: 10.1080/08880018.2017.1313921. Epub 2017 Jul 20.

PMID:
28727494
8.

Primidone inhibits TRPM3 and attenuates thermal nociception in vivo.

Krügel U, Straub I, Beckmann H, Schaefer M.

Pain. 2017 May;158(5):856-867. doi: 10.1097/j.pain.0000000000000846.

9.

Efficacy and safety of BAY 81-8973, a full-length recombinant factor VIII: results from the LEOPOLD I trial.

Saxena K, Lalezari S, Oldenburg J, Tseneklidou-Stoeter D, Beckmann H, Yoon M, Maas Enriquez M.

Haemophilia. 2016 Sep;22(5):706-12. doi: 10.1111/hae.12952. Epub 2016 Jun 24.

PMID:
27339736
10.

BAY 81-8973, a full-length recombinant factor VIII: results from an International comparative laboratory field study.

Kitchen S, Beckmann H, Katterle Y, Bruns S, Tseneklidou-Stoeter D, Maas Enriquez M.

Haemophilia. 2016 May;22(3):e192-9. doi: 10.1111/hae.12925. Epub 2016 Mar 31.

PMID:
27030173
11.

Chromogenic assay for BAY 81-8973 potency assignment has no impact on clinical outcome or monitoring in patient samples.

Kitchen S, Katterle Y, Beckmann H, Maas Enriquez M.

J Thromb Haemost. 2016 Jun;14(6):1192-9. doi: 10.1111/jth.13322. Epub 2016 May 3.

12.

Safety and efficacy of BAY 81-8973 for surgery in previously treated patients with haemophilia A: results of the LEOPOLD clinical trial programme.

Oldenburg J, Windyga J, Hampton K, Lalezari S, Tseneklidou-Stoeter D, Beckmann H, Maas Enriquez M.

Haemophilia. 2016 May;22(3):349-53. doi: 10.1111/hae.12839. Epub 2016 Mar 1.

PMID:
26931631
13.

Spectral sensitivity in Onychophora (velvet worms) revealed by electroretinograms, phototactic behaviour and opsin gene expression.

Beckmann H, Hering L, Henze MJ, Kelber A, Stevenson PA, Mayer G.

J Exp Biol. 2015 Mar;218(Pt 6):915-22. doi: 10.1242/jeb.116780. Epub 2015 Jan 23.

14.

Unfolded Protein Response in Cancer: IRE1α Inhibition by Selective Kinase Ligands Does Not Impair Tumor Cell Viability.

Harrington PE, Biswas K, Malwitz D, Tasker AS, Mohr C, Andrews KL, Dellamaggiore K, Kendall R, Beckmann H, Jaeckel P, Materna-Reichelt S, Allen JR, Lipford JR.

ACS Med Chem Lett. 2014 Sep 24;6(1):68-72. doi: 10.1021/ml500315b. eCollection 2015 Jan 8.

15.

Discovery of 1H-pyrazol-3(2H)-ones as potent and selective inhibitors of protein kinase R-like endoplasmic reticulum kinase (PERK).

Smith AL, Andrews KL, Beckmann H, Bellon SF, Beltran PJ, Booker S, Chen H, Chung YA, D'Angelo ND, Dao J, Dellamaggiore KR, Jaeckel P, Kendall R, Labitzke K, Long AM, Materna-Reichelt S, Mitchell P, Norman MH, Powers D, Rose M, Shaffer PL, Wu MM, Lipford JR.

J Med Chem. 2015 Feb 12;58(3):1426-41. doi: 10.1021/jm5017494. Epub 2015 Jan 14.

PMID:
25587754
16.

Prophylaxis vs. on-demand treatment with BAY 81-8973, a full-length plasma protein-free recombinant factor VIII product: results from a randomized trial (LEOPOLD II).

Kavakli K, Yang R, Rusen L, Beckmann H, Tseneklidou-Stoeter D, Maas Enriquez M; LEOPOLD II Study Investigators.

J Thromb Haemost. 2015 Mar;13(3):360-9.

17.

Protein delivery to vacuole requires SAND protein-dependent Rab GTPase conversion for MVB-vacuole fusion.

Singh MK, Krüger F, Beckmann H, Brumm S, Vermeer JEM, Munnik T, Mayer U, Stierhof YD, Grefen C, Schumacher K, Jürgens G.

Curr Biol. 2014 Jun 16;24(12):1383-1389. doi: 10.1016/j.cub.2014.05.005. Epub 2014 May 29.

18.

Delivery of endocytosed proteins to the cell-division plane requires change of pathway from recycling to secretion.

Richter S, Kientz M, Brumm S, Nielsen ME, Park M, Gavidia R, Krause C, Voss U, Beckmann H, Mayer U, Stierhof YD, Jürgens G.

Elife. 2014 Apr 8;3:e02131. doi: 10.7554/eLife.02131.

19.

A strategy for the diversity-oriented synthesis of macrocyclic scaffolds using multidimensional coupling.

Beckmann HS, Nie F, Hagerman CE, Johansson H, Tan YS, Wilcke D, Spring DR.

Nat Chem. 2013 Oct;5(10):861-7. doi: 10.1038/nchem.1729. Epub 2013 Aug 25.

PMID:
24056343
20.

Discovery of INT131: a selective PPARγ modulator that enhances insulin sensitivity.

Taygerly JP, McGee LR, Rubenstein SM, Houze JB, Cushing TD, Li Y, Motani A, Chen JL, Frankmoelle W, Ye G, Learned MR, Jaen J, Miao S, Timmermans PB, Thoolen M, Kearney P, Flygare J, Beckmann H, Weiszmann J, Lindstrom M, Walker N, Liu J, Biermann D, Wang Z, Hagiwara A, Iida T, Aramaki H, Kitao Y, Shinkai H, Furukawa N, Nishiu J, Nakamura M.

Bioorg Med Chem. 2013 Feb 15;21(4):979-92. doi: 10.1016/j.bmc.2012.11.058. Epub 2012 Dec 10.

PMID:
23294830
21.

High-affinity multivalent wheat germ agglutinin ligands by one-pot click reaction.

Beckmann HS, Möller HM, Wittmann V.

Beilstein J Org Chem. 2012;8:819-26. Epub 2012 Jun 1.

22.

A two-directional strategy for the diversity-oriented synthesis of macrocyclic scaffolds.

O'Connell KM, Beckmann HS, Laraia L, Horsley HT, Bender A, Venkitaraman AR, Spring DR.

Org Biomol Chem. 2012 Oct 7;10(37):7545-51. doi: 10.1039/c2ob26272j.

PMID:
22890306
23.

Preparation of carbohydrate arrays by using Diels-Alder reactions with inverse electron demand.

Beckmann HS, Niederwieser A, Wiessler M, Wittmann V.

Chemistry. 2012 May 21;18(21):6548-54. doi: 10.1002/chem.201200382. Epub 2012 Apr 18.

PMID:
22511395
24.

Diversity-oriented synthesis: producing chemical tools for dissecting biology.

O' Connor CJ, Beckmann HS, Spring DR.

Chem Soc Rev. 2012 Jun 21;41(12):4444-56. doi: 10.1039/c2cs35023h. Epub 2012 Apr 10. Review.

PMID:
22491328
25.

Late spontaneous recanalization of a symptomatically occluded internal carotid artery two years after extra-intracranial bypass. Case report and review of the literature.

Kniemeyer HW, Voshege M, Soliman A, Abu Al Nasr TM, Beckmann H, Edelmann M.

J Cardiovasc Surg (Torino). 2012 Apr;53(2):241-6.

PMID:
22456648
26.

Huntington's disease: objective assessment of posture--a link between motor and functional deficits.

Reilmann R, Rumpf S, Beckmann H, Koch R, Ringelstein EB, Lange HW.

Mov Disord. 2012 Apr;27(4):555-9. doi: 10.1002/mds.24908. Epub 2012 Jan 12.

PMID:
22241673
27.

Novel pyrrolidine melanin-concentrating hormone receptor 1 antagonists with reduced hERG inhibition.

Fox BM, Natero R, Richard K, Connors R, Roveto PM, Beckmann H, Haller K, Golde J, Xiao SH, Kayser F.

Bioorg Med Chem Lett. 2011 Apr 15;21(8):2460-7. doi: 10.1016/j.bmcl.2011.02.046. Epub 2011 Mar 15.

PMID:
21414780
28.
29.

Identification of piperazine-bisamide GHSR antagonists for the treatment of obesity.

Yu M, Lizarzaburu M, Beckmann H, Connors R, Dai K, Haller K, Li C, Liang L, Lindstrom M, Ma J, Motani A, Wanska M, Zhang A, Li L, Medina JC.

Bioorg Med Chem Lett. 2010 Mar 1;20(5):1758-62. doi: 10.1016/j.bmcl.2010.01.043. Epub 2010 Jan 20.

PMID:
20137933
30.

Role of the GNOM gene in Arabidopsis apical-basal patterning--From mutant phenotype to cellular mechanism of protein action.

Richter S, Anders N, Wolters H, Beckmann H, Thomann A, Heinrich R, Schrader J, Singh MK, Geldner N, Mayer U, Jürgens G.

Eur J Cell Biol. 2010 Feb-Mar;89(2-3):138-44. doi: 10.1016/j.ejcb.2009.11.020. Epub 2009 Dec 29. Review.

PMID:
20036441
31.

Rivaroxaban versus enoxaparin for thromboprophylaxis after hip arthroplasty.

Eriksson BI, Borris LC, Friedman RJ, Haas S, Huisman MV, Kakkar AK, Bandel TJ, Beckmann H, Muehlhofer E, Misselwitz F, Geerts W; RECORD1 Study Group.

N Engl J Med. 2008 Jun 26;358(26):2765-75. doi: 10.1056/NEJMoa0800374.

32.

Efficient N-terminal glycoconjugation of proteins by the N-end rule.

Merkel L, Beckmann HS, Wittmann V, Budisa N.

Chembiochem. 2008 May 23;9(8):1220-4. doi: 10.1002/cbic.200800050. No abstract available.

PMID:
18386277
33.

High throughput screening for orphan and liganded GPCRs.

Xiao SH, Reagan JD, Lee PH, Fu A, Schwandner R, Zhao X, Knop J, Beckmann H, Young SW.

Comb Chem High Throughput Screen. 2008 Mar;11(3):195-215. Review.

PMID:
18336213
34.
35.

A quantitative dynamical systems approach to differential learning: self-organization principle and order parameter equations.

Frank TD, Michelbrink M, Beckmann H, Schöllhorn WI.

Biol Cybern. 2008 Jan;98(1):19-31. Epub 2007 Nov 17. Review.

PMID:
18026746
36.

[Surgical practice in an integrated physician network].

Beckmann HJ.

Chirurg. 2006 Aug;Suppl:237-40. German. No abstract available.

PMID:
17855903
37.

[Will carotid thromboendarterectomy remain competitive? Influence of intraoperative duplex ultrasound quality control].

Kniemeyer HW, Sporkmann C, Beckmann H, Martinez R, Sabin-Luzius U, Salem A, Soliman A, Pühler A.

Chirurg. 2007 Mar;78(3):236-45. German.

PMID:
17318463
38.
39.

[Surgical treatment of carotid artery stenosis: still indicated today? Current indications and future requirements--a review].

Kniemeyer HW, Rudofsky G, Bongers V, Beckmann H, Soliman A.

Dtsch Med Wochenschr. 2006 Aug 18;131(33):1819-24. Review. German. No abstract available.

PMID:
16902907
40.

The development concept of "endogenous psychoses".

Beckmann H, Jakob H, Senitz D.

Dialogues Clin Neurosci. 2006;8(1):101-8. Review.

41.

[Cycloid psychoses as atypical manic-depressive disorders. Results of a family study].

Jabs B, Althaus G, Bartsch A, Schmidtke A, Stöber G, Beckmann H, Pfuhlmann B.

Nervenarzt. 2006 Sep;77(9):1096-100, 1102-4. German.

PMID:
16502008
42.

Cycloid psychoses are not part of a bipolar affective spectrum: results of a controlled family study.

Pfuhlmann B, Jabs B, Althaus G, Schmidtke A, Bartsch A, Stöber G, Beckmann H, Franzek E.

J Affect Disord. 2004 Nov 15;83(1):11-9.

PMID:
15546641
43.

(r)-, but not (s)-alpha lipoic acid stimulates deficient brain pyruvate dehydrogenase complex in vascular dementia, but not in Alzheimer dementia.

Frölich L, Götz ME, Weinmüller M, Youdim MB, Barth N, Dirr A, Gsell W, Jellinger K, Beckmann H, Riederer P.

J Neural Transm (Vienna). 2004 Mar;111(3):295-310. Epub 2003 Oct 24.

PMID:
14991456
44.

Pulmonary deposition of monodisperse aerosols in patients with chronic obstructive pulmonary disease.

Meyer T, Müllinger B, Sommerer K, Scheuch G, Brand P, Beckmann H, Häussinger K, Weber N, Siekmeier R.

Exp Lung Res. 2003 Oct-Nov;29(7):475-84.

PMID:
14710439
45.

Peripheral deposition of alpha1-protease inhibitor using commercial inhalation devices.

Brand P, Beckmann H, Maas Enriquez M, Meyer T, Müllinger B, Sommerer K, Weber N, Weuthen T, Scheuch G.

Eur Respir J. 2003 Aug;22(2):263-7.

46.

Increased frequency of dentate granule cells with basal dendrites in the hippocampal formation of schizophrenics.

Lauer M, Beckmann H, Senitz D.

Psychiatry Res. 2003 Feb 15;122(2):89-97.

PMID:
12714173
47.
48.

The genetic heterogeneity of "schizophrenia".

Beckmann H, Franzek E.

World J Biol Psychiatry. 2000 Jan;1(1):35-41.

PMID:
12607231
49.

Polymorphic MAO-A and 5-HT-transporter genes: analysis of interactions in panic disorder.

Sand P, Lesch KP, Catalano M, Bosi M, Syagailo YV, Okladnova O, Di Bella D, Maffei P, Heils A, Friess F, Politi E, Nöthen MM, Franke P, Stöber G, Fritze J, Maier W, Propping P, Beckmann H, Bellodi L, Riederer P, Deckert J.

World J Biol Psychiatry. 2000 Jul;1(3):147-50.

PMID:
12607224
50.

The concept of hebephrenia over the course of time with particular reference to the Wernicke-Kleist-Leonhard School.

Jabs BE, Verdaguer MF, Pfuhlmann B, Bartsch AJ, Beckmann H.

World J Biol Psychiatry. 2002 Oct;3(4):200-6. Review.

PMID:
12516311

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