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Protease-associated import systems are widespread in Gram-negative bacteria.

Grinter R, Leung PM, Wijeyewickrema LC, Littler D, Beckham S, Pike RN, Walker D, Greening C, Lithgow T.

PLoS Genet. 2019 Oct 15;15(10):e1008435. doi: 10.1371/journal.pgen.1008435. eCollection 2019 Oct.


Project Shikamana: Community Empowerment-Based Combination HIV Prevention Significantly Impacts HIV Incidence and Care Continuum Outcomes Among Female Sex Workers in Iringa, Tanzania.

Kerrigan D, Mbwambo J, Likindikoki S, Davis W, Mantsios A, Beckham SW, Leddy A, Shembilu C, Mwampashi A, Aboud S, Galai N.

J Acquir Immune Defic Syndr. 2019 Oct 1;82(2):141-148. doi: 10.1097/QAI.0000000000002123.


Essential elements of a community empowerment approach to HIV prevention among female sex workers engaged in project Shikamana in Iringa, Tanzania.

Leddy AM, Mantsios A, Davis W, Muraleetharan O, Shembilu C, Mwampashi A, Beckham SW, Galai N, Likindikoki S, Mbwambo J, Kerrigan D.

Cult Health Sex. 2019 Sep 9:1-16. doi: 10.1080/13691058.2019.1659999. [Epub ahead of print]


Transgender HIV research: nothing about us without us.

Scheim AI, Appenroth MN, Beckham SW, Goldstein Z, Grinspan MC, Keatley JG, Radix A.

Lancet HIV. 2019 Sep;6(9):e566-e567. doi: 10.1016/S2352-3018(19)30269-3. Epub 2019 Aug 19. No abstract available.


What do we know about community-based health worker programs? A systematic review of existing reviews on community health workers.

Scott K, Beckham SW, Gross M, Pariyo G, Rao KD, Cometto G, Perry HB.

Hum Resour Health. 2018 Aug 16;16(1):39. doi: 10.1186/s12960-018-0304-x.


FusC, a member of the M16 protease family acquired by bacteria for iron piracy against plants.

Grinter R, Hay ID, Song J, Wang J, Teng D, Dhanesakaran V, Wilksch JJ, Davies MR, Littler D, Beckham SA, Henderson IR, Strugnell RA, Dougan G, Lithgow T.

PLoS Biol. 2018 Aug 2;16(8):e2006026. doi: 10.1371/journal.pbio.2006026. eCollection 2018 Aug.


Community Savings Groups, Financial Security, and HIV Risk Among Female Sex Workers in Iringa, Tanzania.

Mantsios A, Galai N, Mbwambo J, Likindikoki S, Shembilu C, Mwampashi A, Beckham SW, Leddy A, Davis W, Sherman S, Kennedy C, Kerrigan D.

AIDS Behav. 2018 Nov;22(11):3742-3750. doi: 10.1007/s10461-018-2065-x.


Combined roles of ATP and small hairpin RNA in the activation of RIG-I revealed by solution-based analysis.

Shah N, Beckham SA, Wilce JA, Wilce MCJ.

Nucleic Acids Res. 2018 Apr 6;46(6):3169-3186. doi: 10.1093/nar/gkx1307.


Experiences with long acting injectable ART: A qualitative study among PLHIV participating in a Phase II study of cabotegravir + rilpivirine (LATTE-2) in the United States and Spain.

Kerrigan D, Mantsios A, Gorgolas M, Montes ML, Pulido F, Brinson C, deVente J, Richmond GJ, Beckham SW, Hammond P, Margolis D, Murray M.

PLoS One. 2018 Jan 5;13(1):e0190487. doi: 10.1371/journal.pone.0190487. eCollection 2018.


Expanding the Menu of HIV Prevention Options: A Qualitative Study of Experiences with Long-Acting Injectable Cabotegravir as PrEP in the Context of a Phase II Trial in the United States.

Kerrigan D, Mantsios A, Grant R, Markowitz M, Defechereux P, La Mar M, Beckham SW, Hammond P, Margolis D, Murray M.

AIDS Behav. 2018 Nov;22(11):3540-3549. doi: 10.1007/s10461-017-2017-x.


TIA-1 RRM23 binding and recognition of target oligonucleotides.

Waris S, García-Mauriño SM, Sivakumaran A, Beckham SA, Loughlin FE, Gorospe M, Díaz-Moreno I, Wilce MCJ, Wilce JA.

Nucleic Acids Res. 2017 May 5;45(8):4944-4957. doi: 10.1093/nar/gkx102.


Project Shikamana: Baseline Findings From a Community Empowerment-Based Combination HIV Prevention Trial Among Female Sex Workers in Iringa, Tanzania.

Kerrigan D, Mbwambo J, Likindikoki S, Beckham S, Mwampashi A, Shembilu C, Mantsios A, Leddy A, Davis W, Galai N.

J Acquir Immune Defic Syndr. 2017 Jan 1;74 Suppl 1:S60-S68.


Marked sex differences in all-cause mortality on antiretroviral therapy in low- and middle-income countries: a systematic review and meta-analysis.

Beckham SW, Beyrer C, Luckow P, Doherty M, Negussie EK, Baral SD.

J Int AIDS Soc. 2016 Nov 8;19(1):21106. doi: 10.7448/IAS.19.1.21106. eCollection 2016. Review.


Structural characterization suggests models for monomeric and dimeric forms of full-length ezrin.

Phang JM, Harrop SJ, Duff AP, Sokolova AV, Crossett B, Walsh JC, Beckham SA, Nguyen CD, Davies RB, Glöckner C, Bromley EH, Wilk KE, Curmi PM.

Biochem J. 2016 Sep 15;473(18):2763-82. doi: 10.1042/BCJ20160541. Epub 2016 Jun 30.


The crystal structure of the tandem-PAS sensing domain of Campylobacter jejuni chemoreceptor Tlp1 suggests indirect mechanism of ligand recognition.

Machuca MA, Liu YC, Beckham SA, Gunzburg MJ, Roujeinikova A.

J Struct Biol. 2016 May;194(2):205-13. doi: 10.1016/j.jsb.2016.02.019. Epub 2016 Feb 24.


Structural basis for amino-acid recognition and transmembrane signalling by tandem Per-Arnt-Sim (tandem PAS) chemoreceptor sensory domains.

Liu YC, Machuca MA, Beckham SA, Gunzburg MJ, Roujeinikova A.

Acta Crystallogr D Biol Crystallogr. 2015 Oct;71(Pt 10):2127-36. doi: 10.1107/S139900471501384X. Epub 2015 Sep 30.


Conserved features in TamA enable interaction with TamB to drive the activity of the translocation and assembly module.

Selkrig J, Belousoff MJ, Headey SJ, Heinz E, Shiota T, Shen HH, Beckham SA, Bamert RS, Phan MD, Schembri MA, Wilce MC, Scanlon MJ, Strugnell RA, Lithgow T.

Sci Rep. 2015 Aug 5;5:12905. doi: 10.1038/srep12905.


The structure of the atypical killer cell immunoglobulin-like receptor, KIR2DL4.

Moradi S, Berry R, Pymm P, Hitchen C, Beckham SA, Wilce MC, Walpole NG, Clements CS, Reid HH, Perugini MA, Brooks AG, Rossjohn J, Vivian JP.

J Biol Chem. 2015 Apr 17;290(16):10460-71. doi: 10.1074/jbc.M114.612291. Epub 2015 Mar 10.


Female sex workers' experiences with intended pregnancy and antenatal care services in southern Tanzania.

Beckham SW, Shembilu CR, Brahmbhatt H, Winch PJ, Beyrer C, Kerrigan DL.

Stud Fam Plann. 2015 Mar;46(1):55-71. doi: 10.1111/j.1728-4465.2015.00015.x.


Cloning, refolding, purification and preliminary crystallographic analysis of the sensory domain of the Campylobacter chemoreceptor for multiple ligands (CcmL).

Machuca MA, Liu YC, Beckham SA, Roujeinikova A.

Acta Crystallogr F Struct Biol Commun. 2015 Feb;71(Pt 2):211-6. doi: 10.1107/S2053230X1500045X. Epub 2015 Jan 28.


'If you have children, you have responsibilities': motherhood, sex work and HIV in southern Tanzania.

Beckham SW, Shembilu CR, Winch PJ, Beyrer C, Kerrigan DL.

Cult Health Sex. 2015;17(2):165-79. doi: 10.1080/13691058.2014.961034. Epub 2014 Oct 1.


Purification and biochemical characterization of DnaK and its transcriptional activator RpoH from Neisseria gonorrhoeae.

Narayanan S, Beckham SA, Davies JK, Roujeinikova A.

Mol Biol Rep. 2014 Dec;41(12):7945-53. doi: 10.1007/s11033-014-3689-1. Epub 2014 Aug 26.


Multi-level factors affecting entry into and engagement in the HIV continuum of care in Iringa, Tanzania.

Layer EH, Kennedy CE, Beckham SW, Mbwambo JK, Likindikoki S, Davis WW, Kerrigan DL, Brahmbhatt H; LTC Tanzania Collaborative Study Team.

PLoS One. 2014 Aug 13;9(8):e104961. doi: 10.1371/journal.pone.0104961. eCollection 2014.


"I pray that they accept me without scolding:" experiences with disengagement and re-engagement in HIV care and treatment services in Tanzania.

Layer EH, Brahmbhatt H, Beckham SW, Ntogwisangu J, Mwampashi A, Davis WW, Kerrigan DL, Kennedy CE.

AIDS Patient Care STDS. 2014 Sep;28(9):483-8. doi: 10.1089/apc.2014.0077. Epub 2014 Aug 5.


Maximizing the benefits of antiretroviral therapy for key affected populations.

Grubb IR, Beckham SW, Kazatchkine M, Thomas RM, Albers ER, Cabral M, Lange J, Vella S, Kurian M, Beyrer C; IAS Treatment for Key Affected Populations Working Group.

J Int AIDS Soc. 2014 Jul 18;17:19320. doi: 10.7448/IAS.17.1.19320. eCollection 2014.


Sensitivity of emergency bedside ultrasound to detect hydronephrosis in patients with computed tomography-proven stones.

Riddell J, Case A, Wopat R, Beckham S, Lucas M, McClung CD, Swadron S.

West J Emerg Med. 2014 Feb;15(1):96-100. doi: 10.5811/westjem.2013.9.15874.


'He is proud of my courage to ask him to be circumcised': experiences of female partners of male circumcision clients in Iringa region, Tanzania.

Layer EH, Beckham SW, Momburi RB, Peter M, Laizer E, Kennedy CE.

Cult Health Sex. 2014 Jan 9. [Epub ahead of print]


Inosine-mediated modulation of RNA sensing by Toll-like receptor 7 (TLR7) and TLR8.

Sarvestani ST, Tate MD, Moffat JM, Jacobi AM, Behlke MA, Miller AR, Beckham SA, McCoy CE, Chen W, Mintern JD, O'Keeffe M, John M, Williams BR, Gantier MP.

J Virol. 2014 Jan;88(2):799-810. doi: 10.1128/JVI.01571-13. Epub 2013 Nov 13.


Quinine binding by the cocaine-binding aptamer. Thermodynamic and hydrodynamic analysis of high-affinity binding of an off-target ligand.

Reinstein O, Yoo M, Han C, Palmo T, Beckham SA, Wilce MC, Johnson PE.

Biochemistry. 2013 Dec 3;52(48):8652-62. doi: 10.1021/bi4010039. Epub 2013 Nov 14.


"After my husband's circumcision, I know that I am safe from diseases": women's attitudes and risk perceptions towards male circumcision in Iringa, Tanzania.

Layer EH, Beckham SW, Mgeni L, Shembilu C, Momburi RB, Kennedy CE.

PLoS One. 2013 Aug 29;8(8):e74391. doi: 10.1371/journal.pone.0074391. eCollection 2013.


The changing cultural and economic dynamics of polygyny and concurrent sexual partnerships in Iringa, Tanzania.

Tomori C, Francisco LV, Kennedy CE, Kajula-Maonga L, Likindikoki S, Babalola SO, Beckham SW, Mbwambo JK, Kerrigan DL.

Glob Public Health. 2013;8(7):857-70. doi: 10.1080/17441692.2013.815249. Epub 2013 Aug 14.


Exploring the potential of a conditional cash transfer intervention to reduce HIV risk among young women in Iringa, Tanzania.

Kennedy CE, Brahmbhatt H, Likindikoki S, Beckham SW, Mbwambo JK, Kerrigan D.

AIDS Care. 2014;26(3):275-81. doi: 10.1080/09540121.2013.824539. Epub 2013 Aug 8.


Structure of the N-terminal domain of human thioredoxin-interacting protein.

Polekhina G, Ascher DB, Kok SF, Beckham S, Wilce M, Waltham M.

Acta Crystallogr D Biol Crystallogr. 2013 Mar;69(Pt 3):333-44. doi: 10.1107/S0907444912047099. Epub 2013 Feb 16.


A framework for understanding grocery purchasing in a low-income urban environment.

Zachary DA, Palmer AM, Beckham SW, Surkan PJ.

Qual Health Res. 2013 May;23(5):665-78. doi: 10.1177/1049732313479451. Epub 2013 Feb 26.


Conformational rearrangements of RIG-I receptor on formation of a multiprotein:dsRNA assembly.

Beckham SA, Brouwer J, Roth A, Wang D, Sadler AJ, John M, Jahn-Hofmann K, Williams BR, Wilce JA, Wilce MC.

Nucleic Acids Res. 2013 Mar 1;41(5):3436-45. doi: 10.1093/nar/gks1477. Epub 2013 Jan 15.


Understanding the partial protection of male circumcision for HIV prevention among women in Iringa Region, Tanzania: an ethnomedical model.

Layer EH, Beckham SW, Momburi RB, Kennedy CE.

AIDS Care. 2013 Aug;25(8):1045-50. doi: 10.1080/09540121.2012.748874. Epub 2012 Dec 7.


Mutations in Hedgehog acyltransferase (Hhat) perturb Hedgehog signaling, resulting in severe acrania-holoprosencephaly-agnathia craniofacial defects.

Dennis JF, Kurosaka H, Iulianella A, Pace J, Thomas N, Beckham S, Williams T, Trainor PA.

PLoS Genet. 2012;8(10):e1002927. doi: 10.1371/journal.pgen.1002927. Epub 2012 Oct 4.


Painful ophthalmoplegia of the right eye in a 20-year-old man.

Beckham S, Kim H, Truong A.

J Emerg Med. 2013 Feb;44(2):e231-4. doi: 10.1016/j.jemermed.2012.07.049. Epub 2012 Sep 13.


The tissue-type plasminogen activator-plasminogen activator inhibitor 1 complex promotes neurovascular injury in brain trauma: evidence from mice and humans.

Sashindranath M, Sales E, Daglas M, Freeman R, Samson AL, Cops EJ, Beckham S, Galle A, McLean C, Morganti-Kossmann C, Rosenfeld JV, Madani R, Vassalli JD, Su EJ, Lawrence DA, Medcalf RL.

Brain. 2012 Nov;135(Pt 11):3251-64. doi: 10.1093/brain/aws178. Epub 2012 Jul 20.


Data bits. Put more pep in your step.

Beckham S, Cox M, Wetterer D.

Ky Nurse. 2012 Jan-Mar;60(1):3. No abstract available.


Analysis of Fasciola cathepsin L5 by S2 subsite substitutions and determination of the P1-P4 specificity reveals an unusual preference.

Norbury LJ, Hung A, Beckham S, Pike RN, Spithill TW, Craik CS, Choe Y, Fecondo JV, Smooker PM.

Biochimie. 2012 May;94(5):1119-27. doi: 10.1016/j.biochi.2012.01.011. Epub 2012 Jan 20.


Engineering a structure switching mechanism into a steroid-binding aptamer and hydrodynamic analysis of the ligand binding mechanism.

Reinstein O, Neves MA, Saad M, Boodram SN, Lombardo S, Beckham SA, Brouwer J, Audette GF, Groves P, Wilce MC, Johnson PE.

Biochemistry. 2011 Nov 1;50(43):9368-76. doi: 10.1021/bi201361v. Epub 2011 Oct 10.


Adult and juvenile Fasciola cathepsin L proteases: different enzymes for different roles.

Norbury LJ, Beckham S, Pike RN, Grams R, Spithill TW, Fecondo JV, Smooker PM.

Biochimie. 2011 Mar;93(3):604-11. doi: 10.1016/j.biochi.2010.12.004. Epub 2010 Dec 16.


Characterization of a serine protease homologous to house dust mite group 3 allergens from the scabies mite Sarcoptes scabiei.

Beckham SA, Boyd SE, Reynolds S, Willis C, Johnstone M, Mika A, Simerská P, Wijeyewickrema LC, Smith AI, Kemp DJ, Pike RN, Fischer K.

J Biol Chem. 2009 Dec 4;284(49):34413-22. doi: 10.1074/jbc.M109.061911. Epub 2009 Oct 7.


The Hawai'i Community Resource Obesity Project: results from the Lifestyle Enhancement Program.

Bradley S, Beckham S, Washburn A.

Hawaii Med J. 2009 May;68(4):80-4.


The potential role of private pharmacies in maternal iron supplementation in rural Tanzania.

Young S, Ali SM, Beckham S.

Food Nutr Bull. 2009 Mar;30(1):16-23.


Structural mechanisms of inactivation in scabies mite serine protease paralogues.

Fischer K, Langendorf CG, Irving JA, Reynolds S, Willis C, Beckham S, Law RH, Yang S, Bashtannyk-Puhalovich TA, McGowan S, Whisstock JC, Pike RN, Kemp DJ, Buckle AM.

J Mol Biol. 2009 Jul 24;390(4):635-45. doi: 10.1016/j.jmb.2009.04.082. Epub 2009 May 7.


A major cathepsin B protease from the liver fluke Fasciola hepatica has atypical active site features and a potential role in the digestive tract of newly excysted juvenile parasites.

Beckham SA, Piedrafita D, Phillips CI, Samarawickrema N, Law RH, Smooker PM, Quinsey NS, Irving JA, Greenwood D, Verhelst SH, Bogyo M, Turk B, Coetzer TH, Wijeyewickrema LC, Spithill TW, Pike RN.

Int J Biochem Cell Biol. 2009 Jul;41(7):1601-12. doi: 10.1016/j.biocel.2009.02.003. Epub 2009 Feb 20.


The effect of insecticide synergists on the response of scabies mites to pyrethroid acaricides.

Pasay C, Arlian L, Morgan M, Gunning R, Rossiter L, Holt D, Walton S, Beckham S, McCarthy J.

PLoS Negl Trop Dis. 2009;3(1):e354. doi: 10.1371/journal.pntd.0000354. Epub 2009 Jan 6.


Diabetes management: utilizing community health workers in a Hawaiian/Samoan population.

Beckham S, Bradley S, Washburn A, Taumua T.

J Health Care Poor Underserved. 2008 May;19(2):416-27. doi: 10.1353/hpu.0.0012.


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