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Items: 1 to 50 of 107

1.

Metabolic engineering of Pseudomonas putida for increased polyhydroxyalkanoate production from lignin.

Salvachúa D, Rydzak T, Auwae R, De Capite A, Black BA, Bouvier JT, Cleveland NS, Elmore JR, Huenemann JD, Katahira R, Michener WE, Peterson DJ, Rohrer H, Vardon DR, Beckham GT, Guss AM.

Microb Biotechnol. 2019 Aug 30. doi: 10.1111/1751-7915.13481. [Epub ahead of print]

2.

Promoting microbial utilization of phenolic substrates from bio-oil.

Davis K, Rover MR, Salvachúa D, Smith RG, Beckham GT, Wen Z, Brown RC, Jarboe LR.

J Ind Microbiol Biotechnol. 2019 Jul 4. doi: 10.1007/s10295-019-02208-z. [Epub ahead of print]

PMID:
31270700
3.

Enabling microbial syringol conversion through structure-guided protein engineering.

Machovina MM, Mallinson SJB, Knott BC, Meyers AW, Garcia-Borràs M, Bu L, Gado JE, Oliver A, Schmidt GP, Hinchen DJ, Crowley MF, Johnson CW, Neidle EL, Payne CM, Houk KN, Beckham GT, McGeehan JE, DuBois JL.

Proc Natl Acad Sci U S A. 2019 Jul 9;116(28):13970-13976. doi: 10.1073/pnas.1820001116. Epub 2019 Jun 24.

4.

Laboratory evolution reveals the metabolic and regulatory basis of ethylene glycol metabolism by Pseudomonas putida KT2440.

Li WJ, Jayakody LN, Franden MA, Wehrmann M, Daun T, Hauer B, Blank LM, Beckham GT, Klebensberger J, Wierckx N.

Environ Microbiol. 2019 Jun 5. doi: 10.1111/1462-2920.14703. [Epub ahead of print]

PMID:
31166064
5.

Radical coupling reactions of piceatannol and monolignols: A density functional theory study.

Elder T, Carlos Del Río J, Ralph J, Rencoret J, Kim H, Beckham GT.

Phytochemistry. 2019 Aug;164:12-23. doi: 10.1016/j.phytochem.2019.04.003. Epub 2019 May 3.

PMID:
31060026
6.

Differences in S/G ratio in natural poplar variants do not predict catalytic depolymerization monomer yields.

Anderson EM, Stone ML, Katahira R, Reed M, Muchero W, Ramirez KJ, Beckham GT, Román-Leshkov Y.

Nat Commun. 2019 May 2;10(1):2033. doi: 10.1038/s41467-019-09986-1.

7.

Nanomechanics of cellulose deformation reveal molecular defects that facilitate natural deconstruction.

Ciesielski PN, Wagner R, Bharadwaj VS, Killgore J, Mittal A, Beckham GT, Decker SR, Himmel ME, Crowley MF.

Proc Natl Acad Sci U S A. 2019 May 14;116(20):9825-9830. doi: 10.1073/pnas.1900161116. Epub 2019 Apr 29.

8.

Sensor-Enabled Alleviation of Product Inhibition in Chorismate Pyruvate-Lyase.

Jha RK, Narayanan N, Pandey N, Bingen JM, Kern TL, Johnson CW, Strauss CEM, Beckham GT, Hennelly SP, Dale T.

ACS Synth Biol. 2019 Apr 19;8(4):775-786. doi: 10.1021/acssynbio.8b00465. Epub 2019 Mar 25.

PMID:
30861344
9.

Activity and Thermostability of GH5 Endoglucanase Chimeras from Mesophilic and Thermophilic Parents.

Zheng F, Vermaas JV, Zheng J, Wang Y, Tu T, Wang X, Xie X, Yao B, Beckham GT, Luo H.

Appl Environ Microbiol. 2019 Feb 20;85(5). pii: e02079-18. doi: 10.1128/AEM.02079-18. Print 2019 Mar 1.

10.

Membrane Permeability of Terpenoids Explored with Molecular Simulation.

Vermaas JV, Bentley GJ, Beckham GT, Crowley MF.

J Phys Chem B. 2018 Nov 15;122(45):10349-10361. doi: 10.1021/acs.jpcb.8b08688. Epub 2018 Nov 1.

PMID:
30352510
11.

A promiscuous cytochrome P450 aromatic O-demethylase for lignin bioconversion.

Mallinson SJB, Machovina MM, Silveira RL, Garcia-Borràs M, Gallup N, Johnson CW, Allen MD, Skaf MS, Crowley MF, Neidle EL, Houk KN, Beckham GT, DuBois JL, McGeehan JE.

Nat Commun. 2018 Jun 27;9(1):2487. doi: 10.1038/s41467-018-04878-2.

12.

Accelerating pathway evolution by increasing the gene dosage of chromosomal segments.

Tumen-Velasquez M, Johnson CW, Ahmed A, Dominick G, Fulk EM, Khanna P, Lee SA, Schmidt AL, Linger JG, Eiteman MA, Beckham GT, Neidle EL.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7105-7110. doi: 10.1073/pnas.1803745115. Epub 2018 Jun 18.

13.

Engineering Pseudomonas putida KT2440 for efficient ethylene glycol utilization.

Franden MA, Jayakody LN, Li WJ, Wagner NJ, Cleveland NS, Michener WE, Hauer B, Blank LM, Wierckx N, Klebensberger J, Beckham GT.

Metab Eng. 2018 Jul;48:197-207. doi: 10.1016/j.ymben.2018.06.003. Epub 2018 Jun 7.

14.

Engineering β-oxidation in Yarrowia lipolytica for methyl ketone production.

Hanko EKR, Denby CM, Sànchez I Nogué V, Lin W, Ramirez KJ, Singer CA, Beckham GT, Keasling JD.

Metab Eng. 2018 Jul;48:52-62. doi: 10.1016/j.ymben.2018.05.018. Epub 2018 May 28.

PMID:
29852272
15.

The impact of O-glycan chemistry on the stability of intrinsically disordered proteins.

Prates ET, Guan X, Li Y, Wang X, Chaffey PK, Skaf MS, Crowley MF, Tan Z, Beckham GT.

Chem Sci. 2018 Mar 20;9(15):3710-3715. doi: 10.1039/c7sc05016j. eCollection 2018 Apr 21.

16.

A protocatechuate biosensor for Pseudomonas putida KT2440 via promoter and protein evolution.

Jha RK, Bingen JM, Johnson CW, Kern TL, Khanna P, Trettel DS, Strauss CEM, Beckham GT, Dale T.

Metab Eng Commun. 2018 Mar 7;6:33-38. doi: 10.1016/j.meteno.2018.03.001. eCollection 2018 Jun.

17.

Catalytic amino acid production from biomass-derived intermediates.

Deng W, Wang Y, Zhang S, Gupta KM, Hülsey MJ, Asakura H, Liu L, Han Y, Karp EM, Beckham GT, Dyson PJ, Jiang J, Tanaka T, Wang Y, Yan N.

Proc Natl Acad Sci U S A. 2018 May 15;115(20):5093-5098. doi: 10.1073/pnas.1800272115. Epub 2018 Apr 30.

18.

Iodine-Catalyzed Isomerization of Dimethyl Muconate.

Settle AE, Berstis L, Zhang S, Rorrer NA, Hu H, Richards RM, Beckham GT, Crowley MF, Vardon DR.

ChemSusChem. 2018 Jun 11;11(11):1768-1780. doi: 10.1002/cssc.201800606. Epub 2018 May 9.

PMID:
29687956
19.

Characterization and engineering of a plastic-degrading aromatic polyesterase.

Austin HP, Allen MD, Donohoe BS, Rorrer NA, Kearns FL, Silveira RL, Pollard BC, Dominick G, Duman R, El Omari K, Mykhaylyk V, Wagner A, Michener WE, Amore A, Skaf MS, Crowley MF, Thorne AW, Johnson CW, Woodcock HL, McGeehan JE, Beckham GT.

Proc Natl Acad Sci U S A. 2018 May 8;115(19):E4350-E4357. doi: 10.1073/pnas.1718804115. Epub 2018 Apr 17.

20.

Engineering enhanced cellobiohydrolase activity.

Taylor LE 2nd, Knott BC, Baker JO, Alahuhta PM, Hobdey SE, Linger JG, Lunin VV, Amore A, Subramanian V, Podkaminer K, Xu Q, VanderWall TA, Schuster LA, Chaudhari YB, Adney WS, Crowley MF, Himmel ME, Decker SR, Beckham GT.

Nat Commun. 2018 Mar 22;9(1):1186. doi: 10.1038/s41467-018-03501-8.

21.

Directed combinatorial mutagenesis of Escherichia coli for complex phenotype engineering.

Liu R, Liang L, Garst AD, Choudhury A, Nogué VSI, Beckham GT, Gill RT.

Metab Eng. 2018 May;47:10-20. doi: 10.1016/j.ymben.2018.02.007. Epub 2018 Mar 29.

PMID:
29477855
22.

Conversion and assimilation of furfural and 5-(hydroxymethyl)furfural by Pseudomonas putida KT2440.

Guarnieri MT, Ann Franden M, Johnson CW, Beckham GT.

Metab Eng Commun. 2017 Feb 8;4:22-28. doi: 10.1016/j.meteno.2017.02.001. eCollection 2017 Jun.

23.

Chemicals from lignin: an interplay of lignocellulose fractionation, depolymerisation, and upgrading.

Schutyser W, Renders T, Van den Bosch S, Koelewijn SF, Beckham GT, Sels BF.

Chem Soc Rev. 2018 Feb 5;47(3):852-908. doi: 10.1039/c7cs00566k. Review.

PMID:
29318245
24.

Distinct roles of N- and O-glycans in cellulase activity and stability.

Amore A, Knott BC, Supekar NT, Shajahan A, Azadi P, Zhao P, Wells L, Linger JG, Hobdey SE, Vander Wall TA, Shollenberger T, Yarbrough JM, Tan Z, Crowley MF, Himmel ME, Decker SR, Beckham GT, Taylor LE 2nd.

Proc Natl Acad Sci U S A. 2017 Dec 26;114(52):13667-13672. doi: 10.1073/pnas.1714249114. Epub 2017 Dec 11.

25.

Renewable acrylonitrile production.

Karp EM, Eaton TR, Sànchez I Nogué V, Vorotnikov V, Biddy MJ, Tan ECD, Brandner DG, Cywar RM, Liu R, Manker LP, Michener WE, Gilhespy M, Skoufa Z, Watson MJ, Fruchey OS, Vardon DR, Gill RT, Bratis AD, Beckham GT.

Science. 2017 Dec 8;358(6368):1307-1310. doi: 10.1126/science.aan1059.

PMID:
29217572
26.

Eliminating a global regulator of carbon catabolite repression enhances the conversion of aromatic lignin monomers to muconate in Pseudomonas putida KT2440.

Johnson CW, Abraham PE, Linger JG, Khanna P, Hettich RL, Beckham GT.

Metab Eng Commun. 2017 May 31;5:19-25. doi: 10.1016/j.meteno.2017.05.002. eCollection 2017 Dec.

27.

Membrane Permeability of Fatty Acyl Compounds Studied via Molecular Simulation.

Vermaas JV, Beckham GT, Crowley MF.

J Phys Chem B. 2017 Dec 21;121(50):11311-11324. doi: 10.1021/acs.jpcb.7b08233. Epub 2017 Nov 1.

PMID:
29040809
28.

Propionic acid production from corn stover hydrolysate by Propionibacterium acidipropionici.

Wang X, Salvachúa D, Sànchez I Nogué V, Michener WE, Bratis AD, Dorgan JR, Beckham GT.

Biotechnol Biofuels. 2017 Aug 17;10:200. doi: 10.1186/s13068-017-0884-z. eCollection 2017.

29.

Metabolic Engineering of Actinobacillus succinogenes Provides Insights into Succinic Acid Biosynthesis.

Guarnieri MT, Chou YC, Salvachúa D, Mohagheghi A, St John PC, Peterson DJ, Bomble YJ, Beckham GT.

Appl Environ Microbiol. 2017 Aug 17;83(17). pii: e00996-17. doi: 10.1128/AEM.00996-17. Print 2017 Sep 1.

30.

CRISPR EnAbled Trackable genome Engineering for isopropanol production in Escherichia coli.

Liang L, Liu R, Garst AD, Lee T, Nogué VSI, Beckham GT, Gill RT.

Metab Eng. 2017 May;41:1-10. doi: 10.1016/j.ymben.2017.02.009. Epub 2017 Feb 16.

PMID:
28216108
31.

Thinking big: towards ideal strains and processes for large-scale aerobic biofuels production.

McMillan JD, Beckham GT.

Microb Biotechnol. 2017 Jan;10(1):40-42. doi: 10.1111/1751-7915.12471. Epub 2016 Dec 22. No abstract available.

32.

Who's on base? Revealing the catalytic mechanism of inverting family 6 glycoside hydrolases.

Mayes HB, Knott BC, Crowley MF, Broadbelt LJ, Ståhlberg J, Beckham GT.

Chem Sci. 2016 Sep 1;7(9):5955-5968. doi: 10.1039/c6sc00571c. Epub 2016 Jun 1.

33.

Coupling and Reactions of 5-Hydroxyconiferyl Alcohol in Lignin Formation.

Elder T, Berstis L, Beckham GT, Crowley MF.

J Agric Food Chem. 2016 Jun 15;64(23):4742-50. doi: 10.1021/acs.jafc.6b02234. Epub 2016 Jun 3.

PMID:
27236926
34.

Succinic acid production from lignocellulosic hydrolysate by Basfia succiniciproducens.

Salvachúa D, Smith H, St John PC, Mohagheghi A, Peterson DJ, Black BA, Dowe N, Beckham GT.

Bioresour Technol. 2016 Aug;214:558-566. doi: 10.1016/j.biortech.2016.05.018. Epub 2016 May 9.

PMID:
27179951
35.

Simulations of cellulose translocation in the bacterial cellulose synthase suggest a regulatory mechanism for the dimeric structure of cellulose.

Knott BC, Crowley MF, Himmel ME, Zimmer J, Beckham GT.

Chem Sci. 2016 May 1;7(5):3108-3116. Epub 2016 Jan 29.

36.

Enhancing muconic acid production from glucose and lignin-derived aromatic compounds via increased protocatechuate decarboxylase activity.

Johnson CW, Salvachúa D, Khanna P, Smith H, Peterson DJ, Beckham GT.

Metab Eng Commun. 2016 Apr 22;3:111-119. doi: 10.1016/j.meteno.2016.04.002. eCollection 2016 Dec.

37.

Biochemical and Structural Characterizations of Two Dictyostelium Cellobiohydrolases from the Amoebozoa Kingdom Reveal a High Level of Conservation between Distant Phylogenetic Trees of Life.

Hobdey SE, Knott BC, Haddad Momeni M, Taylor LE 2nd, Borisova AS, Podkaminer KK, VanderWall TA, Himmel ME, Decker SR, Beckham GT, Ståhlberg J.

Appl Environ Microbiol. 2016 May 16;82(11):3395-409. doi: 10.1128/AEM.00163-16. Print 2016 Jun 1.

38.

Opportunities and challenges in biological lignin valorization.

Beckham GT, Johnson CW, Karp EM, Salvachúa D, Vardon DR.

Curr Opin Biotechnol. 2016 Dec;42:40-53. doi: 10.1016/j.copbio.2016.02.030. Epub 2016 Mar 11. Review.

PMID:
26974563
39.

Succinic acid production on xylose-enriched biorefinery streams by Actinobacillus succinogenes in batch fermentation.

Salvachúa D, Mohagheghi A, Smith H, Bradfield MFA, Nicol W, Black BA, Biddy MJ, Dowe N, Beckham GT.

Biotechnol Biofuels. 2016 Feb 2;9:28. doi: 10.1186/s13068-016-0425-1. eCollection 2016.

40.

Conversion of levoglucosan and cellobiosan by Pseudomonas putida KT2440.

Linger JG, Hobdey SE, Franden MA, Fulk EM, Beckham GT.

Metab Eng Commun. 2016 Feb 2;3:24-29. doi: 10.1016/j.meteno.2016.01.005. eCollection 2016 Dec.

41.

Aromatic-Mediated Carbohydrate Recognition in Processive Serratia marcescens Chitinases.

Jana S, Hamre AG, Wildberger P, Holen MM, Eijsink VG, Beckham GT, Sørlie M, Payne CM.

J Phys Chem B. 2016 Feb 25;120(7):1236-49. doi: 10.1021/acs.jpcb.5b12610. Epub 2016 Feb 15.

PMID:
26824449
42.

Electronic coupling through natural amino acids.

Berstis L, Beckham GT, Crowley MF.

J Chem Phys. 2015 Dec 14;143(22):225102. doi: 10.1063/1.4936588.

PMID:
26671404
43.

Molecular-scale features that govern the effects of O-glycosylation on a carbohydrate-binding module.

Guan X, Chaffey PK, Zeng C, Greene ER, Chen L, Drake MR, Chen C, Groobman A, Resch MG, Himmel ME, Beckham GT, Tan Z.

Chem Sci. 2015 Dec 1;6(12):7185-7189. doi: 10.1039/c5sc02636a. Epub 2015 Sep 21.

44.

Glycosylation of Cellulases: Engineering Better Enzymes for Biofuels.

Greene ER, Himmel ME, Beckham GT, Tan Z.

Adv Carbohydr Chem Biochem. 2015;72:63-112. doi: 10.1016/bs.accb.2015.08.001. Epub 2015 Oct 24. Review.

PMID:
26613815
45.

Lignocellulose degradation mechanisms across the Tree of Life.

Cragg SM, Beckham GT, Bruce NC, Bugg TD, Distel DL, Dupree P, Etxabe AG, Goodell BS, Jellison J, McGeehan JE, McQueen-Mason SJ, Schnorr K, Walton PH, Watts JE, Zimmer M.

Curr Opin Chem Biol. 2015 Dec;29:108-19. doi: 10.1016/j.cbpa.2015.10.018. Epub 2015 Nov 14. Review.

46.

Continuous succinic acid production by Actinobacillus succinogenes on xylose-enriched hydrolysate.

Bradfield MF, Mohagheghi A, Salvachúa D, Smith H, Black BA, Dowe N, Beckham GT, Nicol W.

Biotechnol Biofuels. 2015 Nov 14;8:181. doi: 10.1186/s13068-015-0363-3. eCollection 2015.

47.

Carbocation Stability in H-ZSM5 at High Temperature.

Ferguson GA, Cheng L, Bu L, Kim S, Robichaud DJ, Nimlos MR, Curtiss LA, Beckham GT.

J Phys Chem A. 2015 Nov 19;119(46):11397-405. doi: 10.1021/acs.jpca.5b07025. Epub 2015 Nov 4.

PMID:
26501585
48.

O-glycosylation effects on family 1 carbohydrate-binding module solution structures.

Happs RM, Guan X, Resch MG, Davis MF, Beckham GT, Tan Z, Crowley MF.

FEBS J. 2015 Nov;282(22):4341-56. doi: 10.1111/febs.13500. Epub 2015 Sep 21.

49.

Nucleation rate analysis of methane hydrate from molecular dynamics simulations.

Yuhara D, Barnes BC, Suh D, Knott BC, Beckham GT, Yasuoka K, Wu DT, Sum AK.

Faraday Discuss. 2015;179:463-74. doi: 10.1039/c4fd00219a. Epub 2015 Apr 16.

PMID:
25876773
50.

Ethanol dehydration in HZSM-5 studied by density functional theory: evidence for a concerted process.

Kim S, Robichaud DJ, Beckham GT, Paton RS, Nimlos MR.

J Phys Chem A. 2015 Apr 16;119(15):3604-14. doi: 10.1021/jp513024z. Epub 2015 Apr 6.

PMID:
25802969

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