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Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy combined with liver resection for concurrent peritoneal and hepatic metastases of gastrointestinal and gynecological primary tumors.

Horvath P, Beckert S, Königsrainer A, Nadalin S, Königsrainer I.

J Visc Surg. 2019 Jul 16. pii: S1878-7886(19)30086-4. doi: 10.1016/j.jviscsurg.2019.06.007. [Epub ahead of print]


Peritoneal metastasis in gastric cancer: results from the German database.

Rau B, Brandl A, Piso P, Pelz J, Busch P, Demtröder C, Schüle S, Schlitt HJ, Roitman M, Tepel J, Sulkowski U, Uzunoglu F, Hünerbein M, Hörbelt R, Ströhlein M, Beckert S, Königsrainer I, Königsrainer A; Peritoneum Surface Oncology Group and members of the StuDoQ|Peritoneum Registry of the German Society for General and Visceral Surgery (DGAV).

Gastric Cancer. 2019 Jun 21. doi: 10.1007/s10120-019-00978-0. [Epub ahead of print]


Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma.

Löffler MW, Mohr C, Bichmann L, Freudenmann LK, Walzer M, Schroeder CM, Trautwein N, Hilke FJ, Zinser RS, Mühlenbruch L, Kowalewski DJ, Schuster H, Sturm M, Matthes J, Riess O, Czemmel S, Nahnsen S, Königsrainer I, Thiel K, Nadalin S, Beckert S, Bösmüller H, Fend F, Velic A, Maček B, Haen SP, Buonaguro L, Kohlbacher O, Stevanović S, Königsrainer A; HEPAVAC Consortium, Rammensee HG.

Genome Med. 2019 Apr 30;11(1):28. doi: 10.1186/s13073-019-0636-8.


Systematic Review of Variations in Hyperthermic Intraperitoneal Chemotherapy (HIPEC) for Peritoneal Metastasis from Colorectal Cancer.

Yurttas C, Hoffmann G, Tolios A, Haen SP, Schwab M, Königsrainer I, Königsrainer A, Beckert S, Löffler MW.

J Clin Med. 2018 Dec 19;7(12). pii: E567. doi: 10.3390/jcm7120567. Review.


Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: A safe treatment option for intraperitoneal rhabdomyosarcoma in children below 5 years of age.

Gesche J, Beckert S, Neunhoeffer F, Kachanov D, Königsrainer A, Seitz G, Fuchs J.

Pediatr Blood Cancer. 2019 Feb;66(2):e27517. doi: 10.1002/pbc.27517. Epub 2018 Oct 26.


First case report of malignant peritoneal mesothelioma and oral verrucous carcinoma in a patient with a germline PTEN mutation: a combination of extremely rare diseases with probable further implications.

Löffler MW, Steinhilber J, Hilke FJ, Haen SP, Bösmüller H, Montes-Mojarro IA, Bonzheim I, Stäbler A, Faust U, Grasshoff U, Königsrainer I, Rammensee HG, Kanz L, Königsrainer A, Beckert S, Riess O, Schroeder C.

BMC Med Genet. 2018 Aug 15;19(1):144. doi: 10.1186/s12881-018-0651-4.


Pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastases of pancreas and biliary tract cancer.

Horvath P, Beckert S, Struller F, Königsrainer A, Reymond MA.

Clin Exp Metastasis. 2018 Oct;35(7):635-640. doi: 10.1007/s10585-018-9925-7. Epub 2018 Jul 30.


Mapping the HLA Ligandome of Colorectal Cancer Reveals an Imprint of Malignant Cell Transformation.

Löffler MW, Kowalewski DJ, Backert L, Bernhardt J, Adam P, Schuster H, Dengler F, Backes D, Kopp HG, Beckert S, Wagner S, Königsrainer I, Kohlbacher O, Kanz L, Königsrainer A, Rammensee HG, Stevanović S, Haen SP.

Cancer Res. 2018 Aug 15;78(16):4627-4641. doi: 10.1158/0008-5472.CAN-17-1745. Epub 2018 May 22.


[Oligometastases in gastric and esophageal cancer : Current clinical trials and surgical concepts].

Beckert S, Königsrainer A.

Chirurg. 2018 Jul;89(7):505-509. doi: 10.1007/s00104-018-0645-y. Review. German.


Peritoneal innervation: embryology and functional anatomy.

Struller F, Weinreich FJ, Horvath P, Kokkalis MK, Beckert S, Königsrainer A, Reymond MA.

Pleura Peritoneum. 2017 Dec 1;2(4):153-161. doi: 10.1515/pp-2017-0024.


Therapy Decision Support Based on Recommender System Methods.

Gräßer F, Beckert S, Küster D, Schmitt J, Abraham S, Malberg H, Zaunseder S.

J Healthc Eng. 2017;2017:8659460. doi: 10.1155/2017/8659460. Epub 2017 Mar 28.


Abdominal Wall Morbidity Following Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy.

Struller F, Koenigsrainer I, Horvath P, Koenigsrainer A, Beckert S.

Scand J Surg. 2017 Dec;106(4):294-298. doi: 10.1177/1457496917690989. Epub 2017 Mar 1.


Pharmacodynamics of Oxaliplatin-Derived Platinum Compounds During Hyperthermic Intraperitoneal Chemotherapy (HIPEC): An Emerging Aspect Supporting the Rational Design of Treatment Protocols.

Löffler MW, Schuster H, Zeck A, Quilitz N, Weinreich J, Tolios A, Haen SP, Horvath P, Löb S, Rammensee HG, Königsrainer I, Königsrainer A, Beckert S.

Ann Surg Oncol. 2017 Jun;24(6):1650-1657. doi: 10.1245/s10434-017-5790-x. Epub 2017 Feb 3.


Incidence of leukopenia after intraperitoneal vs combined intravenous/intraperitoneal chemotherapy in pseudomyxoma peritonei.

Horvath P, Beckert S, Struller F, Königsrainer A, Königsrainer I.

World J Gastrointest Pharmacol Ther. 2016 Aug 6;7(3):434-9. doi: 10.4292/wjgpt.v7.i3.434.


Functional vascular anatomy of the peritoneum in health and disease.

Solass W, Horvath P, Struller F, Königsrainer I, Beckert S, Königsrainer A, Weinreich FJ, Schenk M.

Pleura Peritoneum. 2016 Sep 1;1(3):145-158. doi: 10.1515/pp-2016-0015. Epub 2016 Oct 4. Review.


Growth hormone abolishes the negative effects of everolimus on intestinal wound healing.

Küper MA, Trütschel S, Weinreich J, Königsrainer A, Beckert S.

World J Gastroenterol. 2016 May 7;22(17):4321-9. doi: 10.3748/wjg.v22.i17.4321.


Pancreas-preserving surgical management of grade-C pancreatic fistulas after pancreatic head resection by external wirsungostomy.

Horvath P, Beckert S, Nadalin S, Königsrainer A, Königsrainer I.

Langenbecks Arch Surg. 2016 Jun;401(4):457-62. doi: 10.1007/s00423-016-1423-2. Epub 2016 Apr 7.


Overall morbidity but not mortality is increased in elderly patients following cytoreductive surgery and HIPEC.

Beckert S, Struller F, Horvath P, Falcke A, Königsrainer A, Königsrainer I.

Langenbecks Arch Surg. 2015 Aug;400(6):693-8. doi: 10.1007/s00423-015-1325-8. Epub 2015 Aug 6.


Extract from Rumex acetosa L. for prophylaxis of periodontitis: inhibition of bacterial in vitro adhesion and of gingipains of Porphyromonas gingivalis by epicatechin-3-O-(4β→8)-epicatechin-3-O-gallate (procyanidin-B2-Di-gallate).

Schmuch J, Beckert S, Brandt S, Löhr G, Hermann F, Schmidt TJ, Beikler T, Hensel A.

PLoS One. 2015 Mar 24;10(3):e0120130. doi: 10.1371/journal.pone.0120130. eCollection 2015.


The Prognostic Role of Optimal Cytoreduction in Advanced, Bowel Infiltrating Ovarian Cancer.

Bachmann R, Rothmund R, Krämer B, Brucker SY, Königsrainer A, Königsrainer I, Beckert S, Staebler A, NguyenHuu P, Grischke E, Wallwiener D, Bachmann C.

J Invest Surg. 2015 Jun;28(3):160-6. doi: 10.3109/08941939.2014.994794. Epub 2015 Jan 7.


[Cytoreductive surgery and HIPEC for peritoneal malignancies in children].

Seitz G, Fuchs J, Königsrainer I, Warmann SW, Königsrainer A, Beckert S.

Zentralbl Chir. 2014 Dec;139(6):607-12. doi: 10.1055/s-0034-1383240. Epub 2014 Dec 22. Review. German.


Initial clinical experience with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in signet-ring cell gastric cancer with peritoneal metastases.

Königsrainer I, Horvath P, Struller F, Königsrainer A, Beckert S.

J Gastric Cancer. 2014 Jun;14(2):117-22. doi: 10.5230/jgc.2014.14.2.117. Epub 2014 Jun 30.


Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy in recurrent epithelial ovarian cancer with peritoneal metastases: a single centre experience.

Königsrainer I, Horvath P, Struller F, Grischke EM, Wallwiener D, Königsrainer A, Beckert S.

Langenbecks Arch Surg. 2014 Jun;399(5):589-94. doi: 10.1007/s00423-014-1207-5. Epub 2014 May 11.


Assessment of relapse in patients with peritoneal carcinomatosis after cytoreductive surgery and hyperthermic intraperitoneal chemotherapy using F-18-FDG-PET/CT.

Klumpp B, Schwenzer NF, Gatidis S, Koenigsrainer I, Koenigsrainer A, Beckert S, Mueller M, Claussen CD, Pfannenberg C.

Rofo. 2014 Apr;186(4):359-66. doi: 10.1055/s-0034-1366041. Epub 2014 Mar 28.


Correlation of preoperative magnetic resonance imaging of peritoneal carcinomatosis and clinical outcome after peritonectomy and HIPEC after 3 years of follow-up: preliminary results.

Klumpp B, Aschoff P, Schwenzer N, Koenigsrainer I, Beckert S, Claussen CD, Miller S, Koenigsrainer A, Pfannenberg C.

Cancer Imaging. 2013 Dec 30;13(4):540-7. doi: 10.1102/1470-7330.2013.0044.


[Surgical Management of Peritoneal Surface Malignancy with Respect to Tumour Type, Tumour Stage and Individual Tumour Biology].

Beckert S, Struller F, Grischke EM, Glatzle J, Zieker D, Königsrainer A, Königsrainer I.

Zentralbl Chir. 2016 Aug;141(4):415-20. doi: 10.1055/s-0033-1350857. Epub 2013 Nov 15. Review. German.


[Recurrent Peritoneal Metastases after Cytoreductive Surgery and Hyperthermic Intraperitoneal Chemotherapy (HIPEC) in Colorectal Cancer].

Königsrainer I, Struller F, Zieker D, Königsrainer A, Beckert S.

Zentralbl Chir. 2015 Dec;140(6):607-9. doi: 10.1055/s-0032-1328737. Epub 2013 Jul 11. Review. German.


Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy for peritoneal carcinomatosis in a liver graft recipient: a case report.

Horvath P, Königsrainer I, Nadalin S, Beckert S, Löffler M, Königsrainer A.

Ann Transplant. 2013 Apr 22;18:182-6. doi: 10.12659/AOT.883893.


Wound fluid in diabetic foot ulceration: more than just an undefined soup?

Löffler MW, Schuster H, Bühler S, Beckert S.

Int J Low Extrem Wounds. 2013 Jun;12(2):113-29. doi: 10.1177/1534734613489989.


Do patient- and tumor-related factors predict the peritoneal spread of pancreatic adenocarcinoma?

Königsrainer I, Zieker D, Symons S, Horlacher K, Königsrainer A, Beckert S.

Surg Today. 2014 Feb;44(2):260-3. doi: 10.1007/s00595-013-0546-0. Epub 2013 Mar 15.


Risk factors for recurrence following complete cytoreductive surgery and HIPEC in colorectal cancer-derived peritoneal surface malignancies.

Königsrainer I, Horvath P, Struller F, Forkl V, Königsrainer A, Beckert S.

Langenbecks Arch Surg. 2013 Jun;398(5):745-9. doi: 10.1007/s00423-013-1065-6. Epub 2013 Mar 1.


Cytoreductive surgery and hyperthermic intraperitoneal chemotherapy: where are we?

Königsrainer I, Beckert S.

World J Gastroenterol. 2012 Oct 14;18(38):5317-20. doi: 10.3748/wjg.v18.i38.5317. Review.


Impact of endotoxin exposure after exhausting exercise on the immune system in solid organ transplant recipients.

Königsrainer I, Löffler M, Bühler S, Walter M, Schafbuch L, Beckert S, Glatzle J, Horvath P, Northoff H, Nadalin S, Königsrainer A, Zieker D.

Exerc Immunol Rev. 2012;18:177-83.


Superficial wound swabbing: a novel method of sampling and processing wound fluid for subsequent immunoassay analysis in diabetic foot ulcerations.

Schmohl M, Beckert S, Joos TO, Königsrainer A, Schneiderhan-Marra N, Löffler MW.

Diabetes Care. 2012 Nov;35(11):2113-20. doi: 10.2337/dc11-2547. Epub 2012 Jul 26.


Factor XIII Val34Leu polymorphism is associated with increased factor XIII activation and decreased transcutaneous oxygen readings in patients with diabetic foot ulcers.

Küper MA, Schüle R, Mayer P, Königsrainer A, Beckert S.

Diabet Med. 2012 Dec;29(12):1596-9. doi: 10.1111/j.1464-5491.2012.03707.x.


Experience after 100 patients treated with cytoreductive surgery and hyperthermic intraperitoneal chemotherapy.

Königsrainer I, Zieker D, Glatzle J, Lauk O, Klimek J, Symons S, Brücher B, Beckert S, Königsrainer A.

World J Gastroenterol. 2012 May 7;18(17):2061-6. doi: 10.3748/wjg.v18.i17.2061.


X-Nuclei NMR Self-Diffusion Studies in Mesoporous Silica Foam and Microporous MOF CuBTC.

Schlayer S, Pusch AK, Pielenz F, Beckert S, Peksa M, Horch C, Moschkowitz L, Einicke WD, Stallmach F.

Materials (Basel). 2012 Apr 12;5(4):617-633. doi: 10.3390/ma5040617.


[Peritoneal carcinomatosis of colorectal cancer: cytoreductive surgery and hyperthermic intraperitoneal chemotherapy].

Königsrainer I, Beckert S, Brücher B, Zieker D, Königsrainer A.

Dtsch Med Wochenschr. 2011 Sep;136(36):1811-4. doi: 10.1055/s-0031-1286108. Epub 2011 Aug 31. German.


Cytoreductive surgery and HIPEC in peritoneal recurrent ovarian cancer: experience and lessons learned.

Königsrainer I, Beckert S, Becker S, Zieker D, Fehm T, Grischke EM, Lauk O, Glatzle J, Brücher B, Wallwiener D, Königsrainer A.

Langenbecks Arch Surg. 2011 Oct;396(7):1077-81. doi: 10.1007/s00423-011-0835-2. Epub 2011 Aug 13.


Rapamycin-induced impaired wound healing is associated with compromised tissue lactate accumulation and extracellular matrix remodeling.

Weinreich J, Löb S, Löffler M, Königsrainer I, Zieker D, Königsrainer A, Coerper S, Beckert S.

Eur Surg Res. 2011;47(1):39-44. doi: 10.1159/000327972. Epub 2011 May 20.


[Peritoneal carcinomatosis].

Königsrainer I, Beckert S, Lehmann T, Ladurner R, Brücher B, Königsrainer A.

Chirurg. 2011 Apr;82(4):375-80; quiz 381. doi: 10.1007/s00104-010-2049-5. Review. German.


Wound fluid lactate concentration: a helpful marker for diagnosing soft-tissue infection in diabetic foot ulcers? Preliminary findings.

Löffler M, Zieker D, Weinreich J, Löb S, Königsrainer I, Symons S, Bühler S, Königsrainer A, Northoff H, Beckert S.

Diabet Med. 2011 Feb;28(2):175-8. doi: 10.1111/j.1464-5491.2010.03123.x.


Influence of exhaustive exercise on the immune system in solid organ transplant recipients.

Königsrainer I, Zieker D, Löffler M, Bühler S, Walter M, Beckert S, Glatzle J, Northoff H, Nadalin S, Königsrainer A.

Exerc Immunol Rev. 2010;16:184-93.


Circadian expression of clock- and tumor suppressor genes in human oral mucosa.

Zieker D, Jenne I, Koenigsrainer I, Zdichavsky M, Nieselt K, Buck K, Zieker J, Beckert S, Glatzle J, Spanagel R, Koenigsrainer A, Northoff H, Loeffler M.

Cell Physiol Biochem. 2010;26(2):155-66. doi: 10.1159/000320547. Epub 2010 Aug 24.


Phosphoglycerate kinase 1 promoting tumor progression and metastasis in gastric cancer - detected in a tumor mouse model using positron emission tomography/magnetic resonance imaging.

Zieker D, Königsrainer I, Weinreich J, Beckert S, Glatzle J, Nieselt K, Bühler S, Löffler M, Gaedcke J, Northoff H, Mannheim JG, Wiehr S, Pichler BJ, von Weyhern C, Brücher BL, Königsrainer A.

Cell Physiol Biochem. 2010;26(2):147-54. doi: 10.1159/000320545. Epub 2010 Aug 24.


Predictive value of routine transcutaneous tissue oxygen tension (tcpO2) measurement for the risk of non-healing and amputation in diabetic foot ulcer patients with non-palpable pedal pulses.

Ladurner R, Küper M, Königsrainer I, Löb S, Wichmann D, Königsrainer A, Coerper S, Beckert S.

Med Sci Monit. 2010 Jun;16(6):CR273-7.


Mechanical ileus induces surgical intervention due to gastric balloon: a case report and review of the literature.

Zdichavsky M, Beckert S, Kueper M, Kramer M, Königsrainer A.

Obes Surg. 2010 Dec;20(12):1743-6. doi: 10.1007/s11695-010-0114-2.


Effects of isoniazid and niacin on experimental wound-healing.

Weinreich J, Agren MS, Bilali E, Kleinman HK, Coerper S, Königsrainer A, Beckert S.

Surgery. 2010 Jun;147(6):780-8. doi: 10.1016/j.surg.2009.11.003. Epub 2010 Jan 4.


Everolimus interferes with the inflammatory phase of healing in experimental colonic anastomoses.

Küper MA, Schölzl N, Traub F, Mayer P, Weinreich J, Coerper S, Steurer W, Königsrainer A, Beckert S.

J Surg Res. 2011 May 1;167(1):158-65. doi: 10.1016/j.jss.2009.07.013. Epub 2009 Aug 11.


Somatostatin receptor expression in an epitheloid hemangioma causing oncogenic osteomalacia.

Müssig K, Oksüz MO, Pfannenberg C, Adam P, Zustin J, Beckert S, Petersenn S.

J Clin Endocrinol Metab. 2009 Nov;94(11):4123-4. doi: 10.1210/jc.2009-0927. Epub 2009 Sep 29. No abstract available.


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