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Items: 1 to 50 of 144

1.

Longitudinal Analysis of Ventilation Perfusion Mismatch in Congenital Diaphragmatic Hernia Survivors.

Dao DT, Kamran A, Wilson JM, Sheils CA, Kharasch VS, Mullen MP, Rice-Townsend SE, Zalieckas JM, Morash D, Studley M, Staffa SJ, Zurakowski D, Becker RE, Smithers CJ, Buchmiller TL.

J Pediatr. 2019 Nov 5. pii: S0022-3476(19)31219-3. doi: 10.1016/j.jpeds.2019.09.053. [Epub ahead of print]

PMID:
31704054
2.

(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice.

Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh SC, Hoffer BJ, Becker RE, Pick CG, Lupica CR, Greig NH.

Neurobiol Dis. 2019 Oct;130:104528. doi: 10.1016/j.nbd.2019.104528. Epub 2019 Jul 8.

3.

Quantitative Evaluation of Content and Age Concordance Across Developmental Milestone Checklists.

Wilkinson CL, Wilkinson MJ, Lucarelli J, Fogler JM, Becker RE, Huntington N.

J Dev Behav Pediatr. 2019 Sep;40(7):511-518. doi: 10.1097/DBP.0000000000000695.

PMID:
31169653
4.

Can We Prevent Dementia and Not Prevent Neurons from Dying?

Becker RE, Greig NH.

J Alzheimers Dis. 2019;68(2):489-492. doi: 10.3233/JAD-181300.

PMID:
30814363
5.

Neuronal Enriched Extracellular Vesicle Proteins as Biomarkers for Traumatic Brain Injury.

Karnati HK, Garcia JH, Tweedie D, Becker RE, Kapogiannis D, Greig NH.

J Neurotrauma. 2019 Apr 1;36(7):975-987. doi: 10.1089/neu.2018.5898. Epub 2018 Oct 25.

PMID:
30039737
6.

Anatomy, Shoulder and Upper Limb, Ulnar Nerve.

Becker RE, Manna B.

StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2019 Jan-.
2018 Dec 15.

7.

Patients Are Our Teachers.

Becker RE, Seeman MV.

J Patient Cent Res Rev. 2018 Apr 26;5(2):183-186. doi: 10.17294/2330-0698.1589. eCollection 2018 Spring.

8.

(-)-Phenserine and Inhibiting Pre-Programmed Cell Death: In Pursuit of a Novel Intervention for Alzheimer's Disease.

Becker RE, Greig NH, Lahiri DK, Bledsoe J, Majercik S, Ballard C, Aarsland D, Schneider LS, Flanagan D, Govindarajan R, Sano M, Ferrucci L, Kapogiannis D.

Curr Alzheimer Res. 2018;15(9):883-891. doi: 10.2174/1567205015666180110120026. Review.

9.

Does traumatic brain injury hold the key to the Alzheimer's disease puzzle?

Becker RE, Kapogiannis D, Greig NH.

Alzheimers Dement. 2018 Apr;14(4):431-443. doi: 10.1016/j.jalz.2017.11.007. Epub 2017 Dec 12. Review.

10.

(-)-Phenserine inhibits neuronal apoptosis following ischemia/reperfusion injury.

Chang CF, Lai JH, Wu JC, Greig NH, Becker RE, Luo Y, Chen YH, Kang SJ, Chiang YH, Chen KY.

Brain Res. 2017 Dec 15;1677:118-128. doi: 10.1016/j.brainres.2017.09.015. Epub 2017 Sep 27.

11.

Repositioning drugs for traumatic brain injury - N-acetyl cysteine and Phenserine.

Hoffer BJ, Pick CG, Hoffer ME, Becker RE, Chiang YH, Greig NH.

J Biomed Sci. 2017 Sep 9;24(1):71. doi: 10.1186/s12929-017-0377-1. Review.

12.

Public Psychiatry's Accomplishments: Bound for Nowhere?

Becker RE.

Psychiatr Serv. 2017 Jun 1;68(6):641. doi: 10.1176/appi.ps.68603. No abstract available.

PMID:
28566038
13.

Does the ex utero intrapartum treatment to extracorporeal membrane oxygenation procedure change morbidity outcomes for high-risk congenital diaphragmatic hernia survivors?

Shieh HF, Wilson JM, Sheils CA, Smithers CJ, Kharasch VS, Becker RE, Studley M, Morash D, Buchmiller TL.

J Pediatr Surg. 2017 Jan;52(1):22-25. doi: 10.1016/j.jpedsurg.2016.10.010. Epub 2016 Oct 25.

PMID:
27836357
14.

Cognitive Impairments Induced by Concussive Mild Traumatic Brain Injury in Mouse Are Ameliorated by Treatment with Phenserine via Multiple Non-Cholinergic and Cholinergic Mechanisms.

Tweedie D, Fukui K, Li Y, Yu QS, Barak S, Tamargo IA, Rubovitch V, Holloway HW, Lehrmann E, Wood WH 3rd, Zhang Y, Becker KG, Perez E, Van Praag H, Luo Y, Hoffer BJ, Becker RE, Pick CG, Greig NH.

PLoS One. 2016 Jun 2;11(6):e0156493. doi: 10.1371/journal.pone.0156493. eCollection 2016.

15.

Perhaps I Touched the Minaret, or How Patient-Centered Care Remains a Dream.

Becker RE.

Psychiatr Serv. 2016 Apr 1;67(4):375-7. doi: 10.1176/appi.ps.670303. No abstract available.

PMID:
27032797
16.

Prophylactic Bilateral Gonadectomy for Ovotesticular Disorder of Sex Development in a Patient With Mosaic 45,X/46,X,idic(Y)q11.222 Karyotype.

Becker RE, Akhavan A.

Urol Case Rep. 2016 Jan 8;5:13-6. doi: 10.1016/j.eucr.2015.12.003. eCollection 2016 Mar.

17.
18.

What can triumphs and tribulations from drug research in Alzheimer's disease tell us about the development of psychotropic drugs in general?

Becker RE, Seeman MV, Greig NH, Lahiri DK.

Lancet Psychiatry. 2015 Aug;2(8):756-764. doi: 10.1016/S2215-0366(15)00214-X. Review.

19.

Staphylococcus aureus and the skin: a longstanding and complex interaction.

Becker RE, Bubeck Wardenburg J.

Skinmed. 2015 Mar-Apr;13(2):111-9; quiz 120. Review.

PMID:
26137737
20.

Policies and Consequences: How America and Psychiatry Took the Detour to Erewhon.

Becker RE.

Psychiatr Serv. 2015 Oct;66(10):1097-100. doi: 10.1176/appi.ps.201400485. Epub 2015 Jun 15.

PMID:
26073412
21.

Synergistic Action of Staphylococcus aureus α-Toxin on Platelets and Myeloid Lineage Cells Contributes to Lethal Sepsis.

Powers ME, Becker RE, Sailer A, Turner JR, Bubeck Wardenburg J.

Cell Host Microbe. 2015 Jun 10;17(6):775-87. doi: 10.1016/j.chom.2015.05.011.

22.

Remembering Sir William Osler 100 years after his death: what can we learn from his legacy?

Becker RE.

Lancet. 2014 Dec 20;384(9961):2260-3. doi: 10.1016/S0140-6736(14)61887-0. Epub 2014 Dec 19. No abstract available.

PMID:
25625399
23.

Amyloid-β precursor protein synthesis inhibitors for Alzheimer's disease treatment.

Greig NH, Sambamurti K, Lahiri DK, Becker RE.

Ann Neurol. 2014 Oct;76(4):629-30. doi: 10.1002/ana.24254. Epub 2014 Sep 5. No abstract available.

24.

Tissue-specific patterning of host innate immune responses by Staphylococcus aureus α-toxin.

Becker RE, Berube BJ, Sampedro GR, DeDent AC, Bubeck Wardenburg J.

J Innate Immun. 2014;6(5):619-31. doi: 10.1159/000360006. Epub 2014 May 10.

25.

Targeting Staphylococcus aureus α-toxin as a novel approach to reduce severity of recurrent skin and soft-tissue infections.

Sampedro GR, DeDent AC, Becker RE, Berube BJ, Gebhardt MJ, Cao H, Bubeck Wardenburg J.

J Infect Dis. 2014 Oct 1;210(7):1012-8. doi: 10.1093/infdis/jiu223. Epub 2014 Apr 16.

26.

A new regulatory road-map for Alzheimer's disease drug development.

Becker RE, Greig NH.

Curr Alzheimer Res. 2014 Mar;11(3):215-20. Review.

27.

Incretin mimetics as pharmacologic tools to elucidate and as a new drug strategy to treat traumatic brain injury.

Greig NH, Tweedie D, Rachmany L, Li Y, Rubovitch V, Schreiber S, Chiang YH, Hoffer BJ, Miller J, Lahiri DK, Sambamurti K, Becker RE, Pick CG.

Alzheimers Dement. 2014 Feb;10(1 Suppl):S62-75. doi: 10.1016/j.jalz.2013.12.011.

28.

A new roadmap for drug development for Alzheimer's disease.

Becker RE, Greig NH, Giacobini E, Schneider LS, Ferrucci L.

Nat Rev Drug Discov. 2014 Feb;13(2):156. doi: 10.1038/nrd3842-c2. Epub 2013 Dec 20. No abstract available.

29.

Was phenserine a failure or were investigators mislead by methods?

Becker RE, Greig NH.

Curr Alzheimer Res. 2012 Dec;9(10):1174-81.

30.

Managing behavior for a child with autism in a body cast.

Chambers H, Becker RE, Hoffman MT, Hartley-McAndrew M, Stein MT.

J Dev Behav Pediatr. 2012 Jul;33(6):506-8. doi: 10.1097/DBP.0b013e31825ceab0.

PMID:
22635134
31.

Fire in the ashes: can failed Alzheimer's disease drugs succeed with second chances?

Becker RE, Greig NH.

Alzheimers Dement. 2013 Jan;9(1):50-7. doi: 10.1016/j.jalz.2012.01.007. Epub 2012 Mar 30.

32.

Increasing the success rate for Alzheimer's disease drug discovery and development.

Becker RE, Greig NH.

Expert Opin Drug Discov. 2012 Apr;7(4):367-70. doi: 10.1517/17460441.2012.672409. Epub 2012 Mar 23.

33.

Tasquinimod prevents the angiogenic rebound induced by fractionated radiation resulting in an enhanced therapeutic response of prostate cancer xenografts.

Dalrymple SL, Becker RE, Zhou H, DeWeese TL, Isaacs JT.

Prostate. 2012 May 1;72(6):638-48. doi: 10.1002/pros.21467. Epub 2011 Aug 11.

34.

Lost in translation: neuropsychiatric drug development.

Becker RE, Greig NH.

Sci Transl Med. 2010 Dec 8;2(61):61rv6. doi: 10.1126/scitranslmed.3000446. Review.

35.

Phenserine efficacy in Alzheimer's disease.

Winblad B, Giacobini E, Frölich L, Friedhoff LT, Bruinsma G, Becker RE, Greig NH.

J Alzheimers Dis. 2010;22(4):1201-8. doi: 10.3233/JAD-2010-101311.

36.

Why so few drugs for Alzheimer's disease? Are methods failing drugs?

Becker RE, Greig NH.

Curr Alzheimer Res. 2010 Nov;7(7):642-51. Review.

37.

Deletions of NRXN1 (neurexin-1) predispose to a wide spectrum of developmental disorders.

Ching MS, Shen Y, Tan WH, Jeste SS, Morrow EM, Chen X, Mukaddes NM, Yoo SY, Hanson E, Hundley R, Austin C, Becker RE, Berry GT, Driscoll K, Engle EC, Friedman S, Gusella JF, Hisama FM, Irons MB, Lafiosca T, LeClair E, Miller DT, Neessen M, Picker JD, Rappaport L, Rooney CM, Sarco DP, Stoler JM, Walsh CA, Wolff RR, Zhang T, Nasir RH, Wu BL; Children's Hospital Boston Genotype Phenotype Study Group.

Am J Med Genet B Neuropsychiatr Genet. 2010 Jun 5;153B(4):937-47. doi: 10.1002/ajmg.b.31063.

38.

Resurrecting clinical pharmacology as a context for Alzheimer disease drug development.

Becker RE, Unni LK, Greig NH.

Curr Alzheimer Res. 2009 Feb;6(1):79-81. Review.

39.

Neuropsychiatric clinical trials: should they accommodate real-world practices or set standards for clinical practices?

Becker RE, Greig NH.

J Clin Psychopharmacol. 2009 Feb;29(1):56-64. doi: 10.1097/JCP.0b013e318192e2fa.

40.

Alzheimer's disease drug development: old problems require new priorities.

Becker RE, Greig NH.

CNS Neurol Disord Drug Targets. 2008 Dec;7(6):499-511. Review.

41.

Insomnia of childhood.

Lipton J, Becker RE, Kothare SV.

Curr Opin Pediatr. 2008 Dec;20(6):641-9. doi: 10.1097/MOP.0b013e32831897cb. Review.

PMID:
19005332
42.

Why do so many drugs for Alzheimer's disease fail in development? Time for new methods and new practices?

Becker RE, Greig NH, Giacobini E.

J Alzheimers Dis. 2008 Oct;15(2):303-25. Review.

43.

Alzheimer's disease drug development in 2008 and beyond: problems and opportunities.

Becker RE, Greig NH.

Curr Alzheimer Res. 2008 Aug;5(4):346-57. Review.

44.

Lessons from Darwin: 21st century designs for clinical trials.

Becker RE.

Curr Alzheimer Res. 2007 Sep;4(4):458-67. Review.

PMID:
17908050
45.

One hundred years after the discovery of Alzheimer's disease. A turning point for therapy?

Giacobini E, Becker RE.

J Alzheimers Dis. 2007 Aug;12(1):37-52. Review.

PMID:
17851193
47.

Pharmacologic basis for the enhanced efficacy of dutasteride against prostatic cancers.

Xu Y, Dalrymple SL, Becker RE, Denmeade SR, Isaacs JT.

Clin Cancer Res. 2006 Jul 1;12(13):4072-9.

48.

Treating Alzheimer's disease: do clinical trial methods produce unnecessary practitioner dilemmas?

Becker RE.

Am J Alzheimers Dis Other Demen. 2006 Mar-Apr;21(2):81-4.

PMID:
16634462
49.

Age-related changes in phosphorylation of endothelial nitric oxide synthase in the rat penis.

Musicki B, Kramer MF, Becker RE, Burnett AL.

J Sex Med. 2005 May;2(3):347-55; discussion 355-7.

PMID:
16422866
50.

The bedside Osler.

Becker RE.

Osler Libr Newsl. 2006;105:6-7. No abstract available.

PMID:
19226720

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