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21st Century Approaches for Evaluating Exposures, biological activity, and risks of complex substances: Workshop highlights.

Sauer UG, Barter RA, Becker RA, Benfenati E, Berggren E, Hubesch B, Hollnagel HM, Inawaka K, Keene AM, Mayer P, Plotzke K, Skoglund R, Albert O.

Regul Toxicol Pharmacol. 2020 Jan 11:104583. doi: 10.1016/j.yrtph.2020.104583. [Epub ahead of print]


Thank you for 2019.

Karlsson J, Musahl V, Becker R, Hirschmann MT.

Knee Surg Sports Traumatol Arthrosc. 2020 Jan 11. doi: 10.1007/s00167-019-05844-1. [Epub ahead of print] No abstract available.


The noise-resilient brain: Resting-state oscillatory activity predicts words-in-noise recognition.

Houweling T, Becker R, Hervais-Adelman A.

Brain Lang. 2020 Jan 6;202:104727. doi: 10.1016/j.bandl.2019.104727. [Epub ahead of print]


Tissue-level inflammation and ventricular remodeling in hypertrophic cardiomyopathy.

Becker RC, Owens AP 3rd, Sadayappan S.

J Thromb Thrombolysis. 2020 Feb;49(2):177-183. doi: 10.1007/s11239-019-02026-1. Review.


The fate of Baker's cysts at mid-term follow-up after total knee arthroplasty.

Hommel H, Becker R, Fennema P, Kopf S.

Bone Joint J. 2020 Jan;102-B(1):132-136. doi: 10.1302/0301-620X.102B1.BJJ-2019-0273.R2.


Prognostic impact of baseline inflammatory markers in patients with acute coronary syndromes treated with ticagrelor and clopidogrel.

Thomas MR, James SK, Becker RC, Himmelmann A, Katus HA, Cannon CP, Steg PG, Siegbahn A, Lakic T, Storey RF, Wallentin L.

Eur Heart J Acute Cardiovasc Care. 2019 Dec 23:2048872619878075. doi: 10.1177/2048872619878075. [Epub ahead of print]


ALCAM predicts future cardiovascular death in acute coronary syndromes: Insights from the PLATO trial.

Ueland T, Åkerblom A, Ghukasyan T, Michelsen AE, Becker RC, Bertilsson M, Budaj A, Cornel JH, Himmelmann A, James SK, Siegbahn A, Storey RF, Kontny F, Aukrust P, Wallentin L; PLATO Investigators.

Atherosclerosis. 2020 Jan;293:35-41. doi: 10.1016/j.atherosclerosis.2019.11.031. Epub 2019 Nov 29.


(-)-Phenserine tartrate (PhenT) as a treatment for traumatic brain injury.

Greig NH, Lecca D, Hsueh SC, Nogueras-Ortiz C, Kapogiannis D, Tweedie D, Glotfelty EJ, Becker RE, Chiang YH, Hoffer BJ.

CNS Neurosci Ther. 2019 Dec 11. doi: 10.1111/cns.13274. [Epub ahead of print]


Catch-up-ESUS - follow-up in embolic stroke of undetermined source (ESUS) in a prospective, open-label, observational study: study protocol and initial baseline data.

Feil K, Heinrich J, Küpper C, Müller K, Laub C, von Falkenhausen AS, Becker R, Wollenweber FA, Kääb S, Sinner MF, Kellert L.

BMJ Open. 2019 Dec 9;9(12):e031716. doi: 10.1136/bmjopen-2019-031716.


DAISY: A Data Information System for accountability under the General Data Protection Regulation.

Becker R, Alper P, Grouès V, Munoz S, Jarosz Y, Lebioda J, Rege K, Trefois C, Satagopam V, Schneider R.

Gigascience. 2019 Dec 1;8(12). pii: giz140. doi: 10.1093/gigascience/giz140.


Validation of a Novel Device for the Knee Monitoring of Orthopaedic Patients.

Kayaalp ME, Agres AN, Reichmann J, Bashkuev M, Duda GN, Becker R.

Sensors (Basel). 2019 Nov 27;19(23). pii: E5193. doi: 10.3390/s19235193.


The role of fit-for-purpose assays within tiered testing approaches: A case study evaluating prioritized estrogen-active compounds in an in vitro human uterotrophic assay.

Beames T, Moreau M, Roberts LA, Mansouri K, Haider S, Smeltz M, Nicolas CI, Doheny D, Phillips MB, Yoon M, Becker RA, McMullen PD, Andersen ME, Clewell RA, Hartman JK.

Toxicol Appl Pharmacol. 2019 Nov 27;387:114774. doi: 10.1016/j.taap.2019.114774. [Epub ahead of print]


Vibrio cholerae at the Intersection of Immunity and the Microbiome.

Weil AA, Becker RL, Harris JB.

mSphere. 2019 Nov 27;4(6). pii: e00597-19. doi: 10.1128/mSphere.00597-19. Review.


Identification of Candidates for Salvage Therapy: The Past, Present, and Future of Defining Bacillus Calmette-Guérin Failure.

Becker REN, Kates MR, Bivalacqua TJ.

Urol Clin North Am. 2020 Feb;47(1):15-21. doi: 10.1016/j.ucl.2019.09.004. Review.


Geriatric pharmacotherapy: Appraising new drugs for neurologic disorders in older patients.

Seeman MV, Becker RE, Greig NH.

Handb Clin Neurol. 2019;167:3-18. doi: 10.1016/B978-0-12-804766-8.00001-7.


Isolated gracilis tendon harvesting is not associated with loss of strength and maintains good functional outcome.

Flies A, Scheibel M, Kraus N, Kruppa P, Provencher MT, Becker R, Kopf S.

Knee Surg Sports Traumatol Arthrosc. 2019 Nov 16. doi: 10.1007/s00167-019-05790-y. [Epub ahead of print]


Longitudinal Analysis of Pulmonary Function in Survivors of Congenital Diaphragmatic Hernia.

Dao DT, Hayden LP, Buchmiller TL, Kharasch VS, Kamran A, Smithers CJ, Rice-Townsend SE, Zalieckas JM, Becker R, Morash D, Studley M, Wilson JM, Sheils CA.

J Pediatr. 2020 Jan;216:158-164.e2. doi: 10.1016/j.jpeds.2019.09.072. Epub 2019 Nov 6.


Longitudinal Analysis of Ventilation Perfusion Mismatch in Congenital Diaphragmatic Hernia Survivors.

Dao DT, Kamran A, Wilson JM, Sheils CA, Kharasch VS, Mullen MP, Rice-Townsend SE, Zalieckas JM, Morash D, Studley M, Staffa SJ, Zurakowski D, Becker RE, Smithers CJ, Buchmiller TL.

J Pediatr. 2019 Nov 5. pii: S0022-3476(19)31219-3. doi: 10.1016/j.jpeds.2019.09.053. [Epub ahead of print]


Neurocristopathies: Enigmatic Appearances of Neural Crest Cell-derived Abnormalities.

Sato TS, Handa A, Priya S, Watal P, Becker RM, Sato Y.

Radiographics. 2019 Nov-Dec;39(7):2085-2102. doi: 10.1148/rg.2019190086.


Developing context appropriate toxicity testing approaches using new alternative methods (NAMs).

Andersen ME, McMullen PD, Phillips MB, Yoon M, Pendse SN, Clewell HJ, Hartman JK, Moreau M, Becker RA, Clewell RA.

ALTEX. 2019;36(4):523-534. doi: 10.14573/altex.1906261.


Various Patterns of Composition and Accumulation of Steroids and Triterpenoids in Cuticular Waxes from Screened Ericaceae and Caprifoliaceae Berries during Fruit Development.

Dashbaldan S, Becker R, Pączkowski C, Szakiel A.

Molecules. 2019 Oct 23;24(21). pii: E3826. doi: 10.3390/molecules24213826.


A Trans-amplifying RNA Vaccine Strategy for Induction of Potent Protective Immunity.

Beissert T, Perkovic M, Vogel A, Erbar S, Walzer KC, Hempel T, Brill S, Haefner E, Becker R, Türeci Ö, Sahin U.

Mol Ther. 2020 Jan 8;28(1):119-128. doi: 10.1016/j.ymthe.2019.09.009. Epub 2019 Sep 12.


Interleukin-18 in patients with acute coronary syndromes.

Åkerblom A, James SK, Lakic TG, Becker RC, Cannon CP, Steg PG, Himmelmann A, Katus HA, Storey RF, Wallentin L, Weaver WD, Siegbahn A; PLATO Investigators.

Clin Cardiol. 2019 Dec;42(12):1202-1209. doi: 10.1002/clc.23274. Epub 2019 Oct 9.


Reply to the Letter to the Editor: Translation and Validation of the German New Knee Society Scoring System.

Kayaalp ME, Becker R.

Clin Orthop Relat Res. 2019 Nov;477(11):2613-2614. doi: 10.1097/CORR.0000000000000988. No abstract available.


Computed tomography angiography accuracy in brain death diagnosis.

Brasil S, Bor-Seng-Shu E, de-Lima-Oliveira M, Taccone FS, Gattás G, Nunes DM, Gomes de Oliveira RA, Martins Tomazini B, Tierno PF, Becker RA, Bassi E, Sá Malbouisson LM, da Silva Paiva W, Teixeira MJ, de Carvalho Nogueira R.

J Neurosurg. 2019 Sep 27:1-9. doi: 10.3171/2019.6.JNS191107. [Epub ahead of print]


C-X-C Ligand 16 Is an Independent Predictor of Cardiovascular Death and Morbidity in Acute Coronary Syndromes.

Andersen T, Ueland T, Ghukasyan Lakic T, Åkerblom A, Bertilsson M, Aukrust P, Michelsen AE, James SK, Becker RC, Storey RF, Wallentin L, Siegbahn A, Kontny F.

Arterioscler Thromb Vasc Biol. 2019 Nov;39(11):2402-2410. doi: 10.1161/ATVBAHA.119.312633. Epub 2019 Sep 26.


Author Correction: Leveraging European infrastructures to access 1 million human genomes by 2022.

Saunders G, Baudis M, Becker R, Beltran S, Béroud C, Birney E, Brooksbank C, Brunak S, Van den Bulcke M, Drysdale R, Capella-Gutierrez S, Flicek P, Florindi F, Goodhand P, Gut I, Heringa J, Holub P, Hooyberghs J, Juty N, Keane TM, Korbel JO, Lappalainen I, Leskosek B, Matthijs G, Mayrhofer MT, Metspalu A, Navarro A, Newhouse S, Nyrönen T, Page A, Persson B, Palotie A, Parkinson H, Rambla J, Salgado D, Steinfelder E, Swertz MA, Valencia A, Varma S, Blomberg N, Scollen S.

Nat Rev Genet. 2019 Nov;20(11):702. doi: 10.1038/s41576-019-0178-3.


Prevalence and relevance of abnormal glucose metabolism in acute coronary syndromes: insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.

Åkerblom A, Wojdyla D, Steg PG, Wallentin L, James SK, Budaj A, Katus HA, Himmelmann A, Huber K, Siegbahn A, Storey RF, Becker RC; PLATO Investigators.

J Thromb Thrombolysis. 2019 Nov;48(4):563-569. doi: 10.1007/s11239-019-01938-2.


Antithrombotic Therapy in Atrial Fibrillation and Coronary Artery Disease.

Becker RC.

N Engl J Med. 2019 Sep 19;381(12):1169-1170. doi: 10.1056/NEJMe1910560. Epub 2019 Sep 2. No abstract available.


Leveraging European infrastructures to access 1 million human genomes by 2022.

Saunders G, Baudis M, Becker R, Beltran S, Béroud C, Birney E, Brooksbank C, Brunak S, Van den Bulcke M, Drysdale R, Capella-Gutierrez S, Flicek P, Florindi F, Goodhand P, Gut I, Heringa J, Holub P, Hooyberghs J, Juty N, Keane TM, Korbel JO, Lappalainen I, Leskosek B, Matthijs G, Mayrhofer MT, Metspalu A, Navarro A, Newhouse S, Nyrönen T, Page A, Persson B, Palotie A, Parkinson H, Rambla J, Salgado D, Steinfelder E, Swertz MA, Valencia A, Varma S, Blomberg N, Scollen S.

Nat Rev Genet. 2019 Nov;20(11):693-701. doi: 10.1038/s41576-019-0156-9. Epub 2019 Aug 27. Review. Erratum in: Nat Rev Genet. 2019 Sep 13;:.


Tissue Specific Differentiation of Human Chondrocytes Depends on Cell Microenvironment and Serum Selection.

Ecke A, Lutter AH, Scholka J, Hansch A, Becker R, Anderer U.

Cells. 2019 Aug 19;8(8). pii: E934. doi: 10.3390/cells8080934.


Pollen report: quantitative review of pollen crude protein concentrations offered by bee pollinated flowers in agricultural and non-agricultural landscapes.

Pamminger T, Becker R, Himmelreich S, Schneider CW, Bergtold M.

PeerJ. 2019 Aug 12;7:e7394. doi: 10.7717/peerj.7394. eCollection 2019.


Photocatalytic Hydrogen Generation by Vesicle-Embedded [FeFe]Hydrogenase Mimics: A Mechanistic Study.

Becker R, Bouwens T, Schippers ECF, van Gelderen T, Hilbers M, Woutersen S, Reek JNH.

Chemistry. 2019 Nov 4;25(61):13921-13929. doi: 10.1002/chem.201902514. Epub 2019 Sep 26.


Patient-Reported Satisfaction and Study Drug Discontinuation: Post-Hoc Analysis of Findings from ROCKET AF.

Ungar L, Rodriguez F, Hellkamp AS, Becker RC, Berkowitz SD, Breithardt G, Fox KAA, Hacke W, Halperin JL, Hankey GJ, Nessel CC, Singer DE, Patel MR, Piccini JP, Mahaffey KW.

Cardiol Ther. 2019 Dec;8(2):283-295. doi: 10.1007/s40119-019-00146-6. Epub 2019 Aug 2.


Association of Blood Pressure Level With Left Ventricular Mass in Adolescents.

Urbina EM, Mendizábal B, Becker RC, Daniels SR, Falkner BE, Hamdani G, Hanevold C, Hooper SR, Ingelfinger JR, Lanade M, Martin LJ, Meyers K, Mitsnefes M, Rosner B, Samuels J, Flynn JT.

Hypertension. 2019 Sep;74(3):590-596. doi: 10.1161/HYPERTENSIONAHA.119.13027. Epub 2019 Jul 22.


(-)-Phenserine and the prevention of pre-programmed cell death and neuroinflammation in mild traumatic brain injury and Alzheimer's disease challenged mice.

Lecca D, Bader M, Tweedie D, Hoffman AF, Jung YJ, Hsueh SC, Hoffer BJ, Becker RE, Pick CG, Lupica CR, Greig NH.

Neurobiol Dis. 2019 Oct;130:104528. doi: 10.1016/j.nbd.2019.104528. Epub 2019 Jul 8.


NMDA receptor antagonists traxoprodil and lanicemine improve hippocampal-prefrontal coupling and reward-related networks in rats.

Becker R, Gass N, Kußmaul L, Schmid B, Scheuerer S, Schnell D, Dorner-Ciossek C, Weber-Fahr W, Sartorius A.

Psychopharmacology (Berl). 2019 Dec;236(12):3451-3463. doi: 10.1007/s00213-019-05310-3. Epub 2019 Jul 2.


Differences between ketamine's short-term and long-term effects on brain circuitry in depression.

Gass N, Becker R, Reinwald J, Cosa-Linan A, Sack M, Weber-Fahr W, Vollmayr B, Sartorius A.

Transl Psychiatry. 2019 Jun 28;9(1):172. doi: 10.1038/s41398-019-0506-6.


Toward the Development and Application of an Environmental Risk Assessment Framework for Microplastic.

Gouin T, Becker RA, Collot AG, Davis JW, Howard B, Inawaka K, Lampi M, Ramon BS, Shi J, Hopp PW.

Environ Toxicol Chem. 2019 Oct;38(10):2087-2100. doi: 10.1002/etc.4529. Epub 2019 Aug 27. Review.


Alignment in TKA: what has been clear is not anymore!

Hirschmann MT, Becker R, Tandogan R, Vendittoli PA, Howell S.

Knee Surg Sports Traumatol Arthrosc. 2019 Jul;27(7):2037-2039. doi: 10.1007/s00167-019-05558-4. Epub 2019 Jun 12. No abstract available.


Quantitative Evaluation of Content and Age Concordance Across Developmental Milestone Checklists.

Wilkinson CL, Wilkinson MJ, Lucarelli J, Fogler JM, Becker RE, Huntington N.

J Dev Behav Pediatr. 2019 Sep;40(7):511-518. doi: 10.1097/DBP.0000000000000695.


Cash vs. vouchers vs. gifts in web surveys of a mature panel study--Main effects in a long-term incentives experiment across three panel waves.

Becker R, Möser S, Glauser D.

Soc Sci Res. 2019 Jul;81:221-234. doi: 10.1016/j.ssresearch.2019.02.008. Epub 2019 Feb 23.


Possible detrimental effects of beta-2-microglobulin knockout in pigs.

Sake HJ, Frenzel A, Lucas-Hahn A, Nowak-Imialek M, Hassel P, Hadeler KG, Hermann D, Becker R, Eylers H, Hein R, Baars W, Brinkmann A, Schwinzer R, Niemann H, Petersen B.

Xenotransplantation. 2019 Nov;26(6):e12525. doi: 10.1111/xen.12525. Epub 2019 May 22.


Ticagrelor in patients with heart failure after acute coronary syndromes-Insights from the PLATelet inhibition and patient Outcomes (PLATO) trial.

Åkerblom A, Wojdyla DM, Wallentin L, James SK, de Souza Brito F, Steg PG, Cannon CP, Katus HA, Himmelmann A, Storey RF, Becker RC, Lopes RD; PLATO Investigators.

Am Heart J. 2019 Jul;213:57-65. doi: 10.1016/j.ahj.2019.04.006. Epub 2019 Apr 18.


Expression of neurotrophins and their receptors in primary osteosarcoma.

Antunes BP, Becker RG, Brunetto AT, Pavei BS, de-Farias CB, Rivero LFDR, Santos JFC, de-Oliveira BM, Gregianin LJ, Roesler R, Brunetto AL, Pagnussato F, Galia CR.

Rev Col Bras Cir. 2019 May 9;46(2):e2094. doi: 10.1590/0100-6991e-20192094. Portuguese, English.


Association of intronic DNA methylation and hydroxymethylation alterations in the epigenetic etiology of dilated cardiomyopathy.

Tabish AM, Arif M, Song T, Elbeck Z, Becker RC, Knöll R, Sadayappan S.

Am J Physiol Heart Circ Physiol. 2019 Jul 1;317(1):H168-H180. doi: 10.1152/ajpheart.00758.2018. Epub 2019 Apr 26.


Microplastics Can Change Soil Properties and Affect Plant Performance.

de Souza Machado AA, Lau CW, Kloas W, Bergmann J, Bachelier JB, Faltin E, Becker R, Görlich AS, Rillig MC.

Environ Sci Technol. 2019 May 21;53(10):6044-6052. doi: 10.1021/acs.est.9b01339. Epub 2019 May 7.


Pentraxin-3 vs C-reactive protein and other prognostic biomarkers in acute coronary syndrome: A substudy of the Platelet Inhibition and Patients Outcomes (PLATO) trial.

Kontny F, Andersen T, Ueland T, Åkerblom A, Lakic TG, Michelsen AE, Aukrust P, Bertilsson M, Becker RC, Himmelmann A, James SK, Siegbahn A, Storey RF, Wallentin L; PLATO Investigators.

Eur Heart J Acute Cardiovasc Care. 2019 Apr 24:2048872619846334. doi: 10.1177/2048872619846334. [Epub ahead of print]


Acquired Von Willebrand Syndrome (AVWS) in cardiovascular disease: a state of the art review for clinicians.

Mehta R, Athar M, Girgis S, Hassan A, Becker RC.

J Thromb Thrombolysis. 2019 Jul;48(1):14-26. doi: 10.1007/s11239-019-01849-2. Review.


Vibriocidal Titer and Protection From Cholera in Children.

Ritter AS, Chowdhury F, Franke MF, Becker RL, Bhuiyan TR, Khan AI, Saha NC, Ryan ET, Calderwood SB, LaRocque RC, Harris JB, Qadri F, Weil AA.

Open Forum Infect Dis. 2019 Feb 11;6(4):ofz057. doi: 10.1093/ofid/ofz057. eCollection 2019 Apr.

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