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Items: 1 to 50 of 169

1.

Progressive dosage compensation during Drosophila embryogenesis is reflected by gene arrangement.

Prayitno K, Schauer T, Regnard C, Becker PB.

EMBO Rep. 2019 Jul 9:e48138. doi: 10.15252/embr.201948138. [Epub ahead of print]

PMID:
31286660
2.

A Drosophila cell-free system that senses DNA breaks and triggers phosphorylation signalling.

Harpprecht L, Baldi S, Schauer T, Schmidt A, Bange T, Robles MS, Kremmer E, Imhof A, Becker PB.

Nucleic Acids Res. 2019 May 31. pii: gkz473. doi: 10.1093/nar/gkz473. [Epub ahead of print]

PMID:
31147711
3.

Structure, dynamics and roX2-lncRNA binding of tandem double-stranded RNA binding domains dsRBD1,2 of Drosophila helicase Maleless.

Ankush Jagtap PK, Müller M, Masiewicz P, von Bülow S, Hollmann NM, Chen PC, Simon B, Thomae AW, Becker PB, Hennig J.

Nucleic Acids Res. 2019 May 7;47(8):4319-4333. doi: 10.1093/nar/gkz125.

4.

Factor cooperation for chromosome discrimination in Drosophila.

Albig C, Tikhonova E, Krause S, Maksimenko O, Regnard C, Becker PB.

Nucleic Acids Res. 2019 Feb 28;47(4):1706-1724. doi: 10.1093/nar/gky1238.

5.

CHRAC/ACF contribute to the repressive ground state of chromatin.

Scacchetti A, Brueckner L, Jain D, Schauer T, Zhang X, Schnorrer F, van Steensel B, Straub T, Becker PB.

Life Sci Alliance. 2018 Feb 9;1(1):e201800024. doi: 10.26508/lsa.201800024. eCollection 2018 Jan.

6.

Genome-wide Rules of Nucleosome Phasing in Drosophila.

Baldi S, Jain DS, Harpprecht L, Zabel A, Scheibe M, Butter F, Straub T, Becker PB.

Mol Cell. 2018 Nov 15;72(4):661-672.e4. doi: 10.1016/j.molcel.2018.09.032. Epub 2018 Nov 1.

PMID:
30392927
7.

Genome-wide measurement of local nucleosome array regularity and spacing by nanopore sequencing.

Baldi S, Krebs S, Blum H, Becker PB.

Nat Struct Mol Biol. 2018 Sep;25(9):894-901. doi: 10.1038/s41594-018-0110-0. Epub 2018 Aug 20.

PMID:
30127356
8.

Chromosome topology guides the Drosophila Dosage Compensation Complex for target gene activation.

Schauer T, Ghavi-Helm Y, Sexton T, Albig C, Regnard C, Cavalli G, Furlong EE, Becker PB.

EMBO Rep. 2017 Aug 9. pii: e201744292. doi: 10.15252/embr.201744292. [Epub ahead of print]

9.

Ubiquitylation of the acetyltransferase MOF in Drosophila melanogaster.

Schunter S, Villa R, Flynn V, Heidelberger JB, Classen AK, Beli P, Becker PB.

PLoS One. 2017 May 16;12(5):e0177408. doi: 10.1371/journal.pone.0177408. eCollection 2017.

10.

PionX sites mark the X chromosome for dosage compensation.

Villa R, Schauer T, Smialowski P, Straub T, Becker PB.

Nature. 2016 Sep 8;537(7619):244-248. doi: 10.1038/nature19338. Epub 2016 Aug 31.

PMID:
27580037
11.
12.

Combinatorial Histone Acetylation Patterns Are Generated by Motif-Specific Reactions.

Blasi T, Feller C, Feigelman J, Hasenauer J, Imhof A, Theis FJ, Becker PB, Marr C.

Cell Syst. 2016 Jan 27;2(1):49-58. doi: 10.1016/j.cels.2016.01.002. Epub 2016 Jan 27.

13.

High levels of histone H3 acetylation at the CMV promoter are predictive of stable expression in Chinese hamster ovary cells.

Moritz B, Woltering L, Becker PB, Göpfert U.

Biotechnol Prog. 2016 May;32(3):776-86. doi: 10.1002/btpr.2271. Epub 2016 Apr 28.

PMID:
27073121
14.

A role for tuned levels of nucleosome remodeler subunit ACF1 during Drosophila oogenesis.

Börner K, Jain D, Vazquez-Pianzola P, Vengadasalam S, Steffen N, Fyodorov DV, Tomancak P, Konev A, Suter B, Becker PB.

Dev Biol. 2016 Mar 15;411(2):217-230. doi: 10.1016/j.ydbio.2016.01.039. Epub 2016 Feb 2.

15.

Life span extension by targeting a link between metabolism and histone acetylation in Drosophila.

Peleg S, Feller C, Forne I, Schiller E, Sévin DC, Schauer T, Regnard C, Straub T, Prestel M, Klima C, Schmitt Nogueira M, Becker L, Klopstock T, Sauer U, Becker PB, Imhof A, Ladurner AG.

EMBO Rep. 2016 Mar;17(3):455-69. doi: 10.15252/embr.201541132. Epub 2016 Jan 18.

16.

CMV promoter mutants with a reduced propensity to productivity loss in CHO cells.

Moritz B, Becker PB, Göpfert U.

Sci Rep. 2015 Nov 19;5:16952. doi: 10.1038/srep16952.

17.

Structure of the RNA Helicase MLE Reveals the Molecular Mechanisms for Uridine Specificity and RNA-ATP Coupling.

Prabu JR, Müller M, Thomae AW, Schüssler S, Bonneau F, Becker PB, Conti E.

Mol Cell. 2015 Nov 5;60(3):487-99. doi: 10.1016/j.molcel.2015.10.011.

18.

Computational study of remodeling in a nucleosomal array.

Schram RD, Klinker H, Becker PB, Schiessel H.

Eur Phys J E Soft Matter. 2015 Aug;38(8):85. doi: 10.1140/epje/i2015-15085-4. Epub 2015 Aug 10.

PMID:
26248702
19.

Active promoters give rise to false positive 'Phantom Peaks' in ChIP-seq experiments.

Jain D, Baldi S, Zabel A, Straub T, Becker PB.

Nucleic Acids Res. 2015 Aug 18;43(14):6959-68. doi: 10.1093/nar/gkv637. Epub 2015 Jun 27.

20.

Beads-on-a-string on a bead: reconstitution and analysis of chromatin on a solid support.

Sandaltzopoulos R, Becker PB.

Methods Mol Biol. 2015;1288:1-14. doi: 10.1007/978-1-4939-2474-5_1.

PMID:
25827871
21.

Global and specific responses of the histone acetylome to systematic perturbation.

Feller C, Forné I, Imhof A, Becker PB.

Mol Cell. 2015 Feb 5;57(3):559-71. doi: 10.1016/j.molcel.2014.12.008. Epub 2015 Jan 8.

22.

Structural basis of X chromosome DNA recognition by the MSL2 CXC domain during Drosophila dosage compensation.

Zheng S, Villa R, Wang J, Feng Y, Wang J, Becker PB, Ye K.

Genes Dev. 2014 Dec 1;28(23):2652-62. doi: 10.1101/gad.250936.114.

23.

UNR facilitates the interaction of MLE with the lncRNA roX2 during Drosophila dosage compensation.

Militti C, Maenner S, Becker PB, Gebauer F.

Nat Commun. 2014 Aug 27;5:4762. doi: 10.1038/ncomms5762.

PMID:
25158899
24.

Rapid purification of recombinant histones.

Klinker H, Haas C, Harrer N, Becker PB, Mueller-Planitz F.

PLoS One. 2014 Aug 4;9(8):e104029. doi: 10.1371/journal.pone.0104029. eCollection 2014.

25.

The histone-fold protein CHRAC14 influences chromatin composition in response to DNA damage.

Mathew V, Pauleau AL, Steffen N, Bergner A, Becker PB, Erhardt S.

Cell Rep. 2014 Apr 24;7(2):321-330. doi: 10.1016/j.celrep.2014.03.008. Epub 2014 Apr 3.

26.

ISWI remodelling of physiological chromatin fibres acetylated at lysine 16 of histone H4.

Klinker H, Mueller-Planitz F, Yang R, Forné I, Liu CF, Nordenskiöld L, Becker PB.

PLoS One. 2014 Feb 6;9(2):e88411. doi: 10.1371/journal.pone.0088411. eCollection 2014.

27.

Nucleosome sliding mechanisms: new twists in a looped history.

Mueller-Planitz F, Klinker H, Becker PB.

Nat Struct Mol Biol. 2013 Sep;20(9):1026-32. doi: 10.1038/nsmb.2648. Review.

PMID:
24008565
28.

Nucleosome remodeling and epigenetics.

Becker PB, Workman JL.

Cold Spring Harb Perspect Biol. 2013 Sep 1;5(9). pii: a017905. doi: 10.1101/cshperspect.a017905. Review.

29.

ATP-dependent roX RNA remodeling by the helicase maleless enables specific association of MSL proteins.

Maenner S, Müller M, Fröhlich J, Langer D, Becker PB.

Mol Cell. 2013 Jul 25;51(2):174-84. doi: 10.1016/j.molcel.2013.06.011.

30.

Comment on "Drosophila dosage compensation involves enhanced Pol II recruitment to male X-linked promoters".

Straub T, Becker PB.

Science. 2013 Apr 19;340(6130):273. doi: 10.1126/science.1231895.

31.

The variant histone H2A.V of Drosophila--three roles, two guises.

Baldi S, Becker PB.

Chromosoma. 2013 Aug;122(4):245-58. doi: 10.1007/s00412-013-0409-x. Epub 2013 Apr 4. Review.

PMID:
23553272
32.

Different chromatin interfaces of the Drosophila dosage compensation complex revealed by high-shear ChIP-seq.

Straub T, Zabel A, Gilfillan GD, Feller C, Becker PB.

Genome Res. 2013 Mar;23(3):473-85. doi: 10.1101/gr.146407.112. Epub 2012 Dec 11.

33.

The ATPase domain of ISWI is an autonomous nucleosome remodeling machine.

Mueller-Planitz F, Klinker H, Ludwigsen J, Becker PB.

Nat Struct Mol Biol. 2013 Jan;20(1):82-9. doi: 10.1038/nsmb.2457. Epub 2012 Dec 2.

PMID:
23202585
34.

MSL2 combines sensor and effector functions in homeostatic control of the Drosophila dosage compensation machinery.

Villa R, Forné I, Müller M, Imhof A, Straub T, Becker PB.

Mol Cell. 2012 Nov 30;48(4):647-54. doi: 10.1016/j.molcel.2012.09.012. Epub 2012 Oct 18.

35.

Nucleosome remodeler SNF2L suppresses cell proliferation and migration and attenuates Wnt signaling.

Eckey M, Kuphal S, Straub T, Rümmele P, Kremmer E, Bosserhoff AK, Becker PB.

Mol Cell Biol. 2012 Jul;32(13):2359-71. doi: 10.1128/MCB.06619-11. Epub 2012 Apr 16.

36.

Roles of long, non-coding RNA in chromosome-wide transcription regulation: lessons from two dosage compensation systems.

Maenner S, Müller M, Becker PB.

Biochimie. 2012 Jul;94(7):1490-8. doi: 10.1016/j.biochi.2011.12.026. Epub 2012 Jan 8. Review.

PMID:
22239950
37.

A defined in vitro system to study ATP-dependent remodeling of short chromatin fibers.

Maier VK, Becker PB.

Methods Mol Biol. 2012;833:255-70. doi: 10.1007/978-1-61779-477-3_16.

PMID:
22183599
38.

Probing the conformation of the ISWI ATPase domain with genetically encoded photoreactive crosslinkers and mass spectrometry.

Forné I, Ludwigsen J, Imhof A, Becker PB, Mueller-Planitz F.

Mol Cell Proteomics. 2012 Apr;11(4):M111.012088. doi: 10.1074/mcp.M111.012088. Epub 2011 Dec 13.

39.

The MOF-containing NSL complex associates globally with housekeeping genes, but activates only a defined subset.

Feller C, Prestel M, Hartmann H, Straub T, Söding J, Becker PB.

Nucleic Acids Res. 2012 Feb;40(4):1509-22. doi: 10.1093/nar/gkr869. Epub 2011 Oct 27.

40.

Role for hACF1 in the G2/M damage checkpoint.

Sánchez-Molina S, Mortusewicz O, Bieber B, Auer S, Eckey M, Leonhardt H, Friedl AA, Becker PB.

Nucleic Acids Res. 2011 Oct;39(19):8445-56. doi: 10.1093/nar/gkr435. Epub 2011 Jul 11.

41.

Global analysis of the relationship between JIL-1 kinase and transcription.

Regnard C, Straub T, Mitterweger A, Dahlsveen IK, Fabian V, Becker PB.

PLoS Genet. 2011 Mar;7(3):e1001327. doi: 10.1371/journal.pgen.1001327. Epub 2011 Mar 10.

42.

Transcription modulation chromosome-wide: universal features and principles of dosage compensation in worms and flies.

Straub T, Becker PB.

Curr Opin Genet Dev. 2011 Apr;21(2):147-53. doi: 10.1016/j.gde.2011.01.012. Review.

PMID:
21316939
43.

Developmental role for ACF1-containing nucleosome remodellers in chromatin organisation.

Chioda M, Vengadasalam S, Kremmer E, Eberharter A, Becker PB.

Development. 2010 Oct;137(20):3513-22. doi: 10.1242/dev.048405. Epub 2010 Sep 15.

44.

Nucleosome dynamics and epigenetic stability.

Korber P, Becker PB.

Essays Biochem. 2010 Sep 20;48(1):63-74. doi: 10.1042/bse0480063. Review.

PMID:
20822486
45.

Dosage compensation and the global re-balancing of aneuploid genomes.

Prestel M, Feller C, Becker PB.

Genome Biol. 2010;11(8):216. doi: 10.1186/gb-2010-11-8-216. Epub 2010 Aug 26. Review.

46.

Form and function of dosage-compensated chromosomes--a chicken-and-egg relationship.

Grimaud C, Becker PB.

Bioessays. 2010 Aug;32(8):709-17. doi: 10.1002/bies.201000029. Review.

PMID:
20658709
47.

The activation potential of MOF is constrained for dosage compensation.

Prestel M, Feller C, Straub T, Mitlöhner H, Becker PB.

Mol Cell. 2010 Jun 25;38(6):815-26. doi: 10.1016/j.molcel.2010.05.022.

48.

Phosphorylation of SU(VAR)3-9 by the chromosomal kinase JIL-1.

Boeke J, Regnard C, Cai W, Johansen J, Johansen KM, Becker PB, Imhof A.

PLoS One. 2010 Apr 6;5(4):e10042. doi: 10.1371/journal.pone.0010042.

49.

Soft skills turned into hard facts: nucleosome remodelling at developmental switches.

Chioda M, Becker PB.

Heredity (Edinb). 2010 Jul;105(1):71-9. doi: 10.1038/hdy.2010.34. Epub 2010 Apr 7. Review.

50.

The DNA binding CXC domain of MSL2 is required for faithful targeting the Dosage Compensation Complex to the X chromosome.

Fauth T, Müller-Planitz F, König C, Straub T, Becker PB.

Nucleic Acids Res. 2010 Jun;38(10):3209-21. doi: 10.1093/nar/gkq026. Epub 2010 Feb 5.

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