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MRI-derived regional flow-volume loop parameters detect early-stage chronic lung allograft dysfunction.

Moher Alsady T, Voskrebenzev A, Greer M, Becker L, Kaireit TF, Welte T, Wacker F, Gottlieb J, Vogel-Claussen J.

J Magn Reson Imaging. 2019 May 27. doi: 10.1002/jmri.26799. [Epub ahead of print]


A pilot study of respiratory rate derived from a wearable biosensor compared with capnography in emergency department patients.

Li T, Divatia S, McKittrick J, Moss J, Hijnen NM, Becker LB.

Open Access Emerg Med. 2019 May 7;11:103-108. doi: 10.2147/OAEM.S198842. eCollection 2019.


Low catalytic activity is insufficient to induce disease pathology in triosephosphate isomerase deficiency.

Segal J, Mülleder M, Krüger A, Adler T, Scholze-Wittler M, Becker L, Calzada-Wack J, Garrett L, Hölter SM, Rathkolb B, Rozman J, Racz I, Fischer R, Busch DH, Neff F, Klingenspor M, Klopstock T, Grüning NM, Michel S, Lukaszewska-McGreal B, Voigt I, Hartmann L, Timmermann B, Lehrach H, Wolf E, Wurst W, Gailus-Durner V, Fuchs H, H de Angelis M, Schrewe H, Yuneva M, Ralser M.

J Inherit Metab Dis. 2019 May 20. doi: 10.1002/jimd.12105. [Epub ahead of print]


Vagus Nerve Stimulation and the Cardiovascular System.

Capilupi MJ, Kerath SM, Becker LB.

Cold Spring Harb Perspect Med. 2019 May 20. pii: a034173. doi: 10.1101/cshperspect.a034173. [Epub ahead of print]


Altered inhibition and excitation in neocortical circuits in congenital microcephaly.

Zaqout S, Blaesius K, Wu YJ, Ott S, Kraemer N, Becker LL, Rosário M, Rosenmund C, Strauss U, Kaindl AM.

Neurobiol Dis. 2019 May 15;129:130-143. doi: 10.1016/j.nbd.2019.05.008. [Epub ahead of print]


Time course of the physiological stress response to an acute stressor and its associations with the primacy and recency effect of the serial position curve.

Becker L, Rohleder N.

PLoS One. 2019 May 17;14(5):e0213883. doi: 10.1371/journal.pone.0213883. eCollection 2019.


In-depth proteomic characterization of Schistosoma haematobium: Towards the development of new tools for elimination.

Sotillo J, Pearson MS, Becker L, Mekonnen GG, Amoah AS, van Dam G, Corstjens PLAM, Murray J, Mduluza T, Mutapi F, Loukas A.

PLoS Negl Trop Dis. 2019 May 15;13(5):e0007362. doi: 10.1371/journal.pntd.0007362. eCollection 2019 May.


New insights into the kinetics and variability of egg excretion in controlled human hookworm infections.

Hoogerwerf MA, Coffeng LE, Brienen EAT, Janse JJ, Langenberg MCC, Kruize YCM, Gootjes C, Manurung MD, Dekker M, Becker L, Erkens MAA, van der Beek MT, Ganesh MS, Feijt C, Winkel BMF, Westra IM, Meij P, Loukas A, Visser LG, de Vlas SJ, Yazdanbakhsh M, van Lieshout L, Roestenberg M.

J Infect Dis. 2019 May 11. pii: jiz218. doi: 10.1093/infdis/jiz218. [Epub ahead of print]


Mendelian randomization evaluation of causal effects of fibrinogen on incident coronary heart disease.

Ward-Caviness CK, de Vries PS, Wiggins KL, Huffman JE, Yanek LR, Bielak LF, Giulianini F, Guo X, Kleber ME, Kacprowski T, Groß S, Petersman A, Davey Smith G, Hartwig FP, Bowden J, Hemani G, Müller-Nuraysid M, Strauch K, Koenig W, Waldenberger M, Meitinger T, Pankratz N, Boerwinkle E, Tang W, Fu YP, Johnson AD, Song C, de Maat MPM, Uitterlinden AG, Franco OH, Brody JA, McKnight B, Chen YI, Psaty BM, Mathias RA, Becker DM, Peyser PA, Smith JA, Bielinski SJ, Ridker PM, Taylor KD, Yao J, Tracy R, Delgado G, Trompet S, Sattar N, Jukema JW, Becker LC, Kardia SLR, Rotter JI, März W, Dörr M, Chasman DI, Dehghan A, O'Donnell CJ, Smith NL, Peters A, Morrison AC.

PLoS One. 2019 May 10;14(5):e0216222. doi: 10.1371/journal.pone.0216222. eCollection 2019.


Does training level affect the accuracy of visual assessment of capillary refill time?

Shinozaki K, Jacobson LS, Saeki K, Kobayashi N, Weisner S, Falotico JM, Li T, Kim J, Lampe JW, Becker LB.

Crit Care. 2019 May 6;23(1):157. doi: 10.1186/s13054-019-2444-3. No abstract available.


Metabolically activated adipose tissue macrophages link obesity to triple-negative breast cancer.

Tiwari P, Blank A, Cui C, Schoenfelt KQ, Zhou G, Xu Y, Khramtsova G, Olopade F, Shah AM, Khan SA, Rosner MR, Becker L.

J Exp Med. 2019 Jun 3;216(6):1345-1358. doi: 10.1084/jem.20181616. Epub 2019 May 3.


Comparison of two measurement strategies to obtain the residence time distribution in combustion chambers using tunable diode laser absorption spectroscopy.

Bürkle S, Becker LG, Agizza MA, Dreizler A, Wagner S.

Appl Opt. 2019 Apr 1;58(10):C36-C46. doi: 10.1364/AO.58.000C36.


Phosphodiesterase 5 inhibition improves contractile function and restores transverse tubule loss and catecholamine responsiveness in heart failure.

Lawless M, Caldwell JL, Radcliffe EJ, Smith CER, Madders GWP, Hutchings DC, Woods LS, Church SJ, Unwin RD, Kirkwood GJ, Becker LK, Pearman CM, Taylor RF, Eisner DA, Dibb KM, Trafford AW.

Sci Rep. 2019 May 1;9(1):6801. doi: 10.1038/s41598-019-42592-1.


Effects of Recent Concussion and Injury History on Instantaneous Relative Risk of Lower Extremity Injury in Division I Collegiate Athletes.

Fino PC, Becker LN, Fino NF, Griesemer B, Goforth M, Brolinson PG.

Clin J Sport Med. 2019 May;29(3):218-223. doi: 10.1097/JSM.0000000000000502.


Mutation in the mouse histone gene Hist2h3c1 leads to degeneration of the lens vesicle and severe microphthalmia.

Vetrivel S, Tiso N, Kügler A, Irmler M, Horsch M, Beckers J, Hladik D, Giesert F, Gailus-Durner V, Fuchs H, Sabrautzki S; German Mouse Clinic, Helmholtz Zentrum München, German Research Center for Environmental Health GmbH, Neuherberg, Germany, Adler T, Treise I, Busch DH, Aguilar-Pimentel A, Ollert M, Götz A, Amarie OV, Stoeger T, Schulz H, Becker L, Klopstock T, Schrewe A, Spielmann N, Bekeredjian R, Garrett L, Hölter SM, Zimprich A, Wurst W, Mayer-Kuckuk P, Hans W, Rozman J, Klingenspor M, Neff F, da Silva-Buttkus P, Calzada-Wack J, Rácz I, Zimmer A, Rathkolb B, Wolf E, Prehn C, Adamski J, Östereicher M, Miller G, Steinkamp R, Lengger C, Maier H, Stoeger C, Leuchtenberger S, Gailus-Durner V, Fuchs H, Hrabě de Angelis M, Hrabě de Angelis M, Graw J.

Exp Eye Res. 2019 Apr 13. pii: S0014-4835(18)30702-4. doi: 10.1016/j.exer.2019.03.024. [Epub ahead of print]


Challenges and Inconsistencies in Using Lysophosphatidic Acid as a Biomarker for Ovarian Cancer.

Yagi T, Shoaib M, Kuschner C, Nishikimi M, Becker LB, Lee AT, Kim J.

Cancers (Basel). 2019 Apr 11;11(4). pii: E520. doi: 10.3390/cancers11040520.


Genes Whose Gain or Loss-of-Function Increases Endurance Performance in Mice: A Systematic Literature Review.

Yaghoob Nezhad F, Verbrugge SAJ, Schönfelder M, Becker L, Hrabě de Angelis M, Wackerhage H.

Front Physiol. 2019 Mar 22;10:262. doi: 10.3389/fphys.2019.00262. eCollection 2019. Review.


Unilateral Swelling and Functional Impairment of Unknown Origin in the Right Arm.

Reinecke FC, Becker L, Jäger M.

Dtsch Arztebl Int. 2019 Mar 1;116(9):143. doi: 10.3238/arztebl.2019.0143. No abstract available.


Evolution of Hominin Polyunsaturated Fatty Acid Metabolism: From Africa to the New World.

Harris DN, Ruczinski I, Yanek LR, Becker LC, Becker DM, Guio H, Cui T, Chilton FH, Mathias RA, O'Connor TD.

Genome Biol Evol. 2019 May 1;11(5):1417-1430. doi: 10.1093/gbe/evz071.


Trapped! A Critical Evaluation of Methods for Measuring Total Cellular Uptake versus Cytosolic Localization.

Deprey K, Becker L, Kritzer J, Plückthun A.

Bioconjug Chem. 2019 Apr 17;30(4):1006-1027. doi: 10.1021/acs.bioconjchem.9b00112. Epub 2019 Apr 5.


Influenza A (H3) Outbreak at a Hurricane Harvey Megashelter in Harris County, Texas: Successes and Challenges in Disease Identification and Control Measure Implementation.

Liu L, Haynie A, Jin S, Zangeneh A, Bakota E, Hornstein BD, Beckham D, Reed BC, Kiger J, McClendon M, Perez E, Schaffer M, Becker L, Shah UA.

Disaster Med Public Health Prep. 2019 Feb;13(1):97-101. doi: 10.1017/dmp.2018.159.


ATP signaling and NTPDase in Systemic Lupus Erythematosus (SLE).

Becker LV, Passos DF, Leal DBR, Morsch VM, Schetinger MRC.

Immunobiology. 2019 Feb 8. pii: S0171-2985(18)30216-X. doi: 10.1016/j.imbio.2019.02.005. [Epub ahead of print] Review.


Leveraging linkage evidence to identify low-frequency and rare variants on 16p13 associated with blood pressure using TOPMed whole genome sequencing data.

He KY, Li X, Kelly TN, Liang J, Cade BE, Assimes TL, Becker LC, Beitelshees AL, Bress AP, Chang YC, Chen YI, de Vries PS, Fox ER, Franceschini N, Furniss A, Gao Y, Guo X, Haessler J, Hwang SJ, Irvin MR, Kalyani RR, Liu CT, Liu C, Martin LW, Montasser ME, Muntner PM, Mwasongwe S, Palmas W, Reiner AP, Shimbo D, Smith JA, Snively BM, Yanek LR, Boerwinkle E, Correa A, Cupples LA, He J, Kardia SLR, Kooperberg C, Mathias RA, Mitchell BD, Psaty BM, Vasan RS, Rao DC, Rich SS, Rotter JI, Wilson JG; NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium, TOPMed Blood Pressure Working Group, Chakravarti A, Morrison AC, Levy D, Arnett DK, Redline S, Zhu X.

Hum Genet. 2019 Feb;138(2):199-210. doi: 10.1007/s00439-019-01975-0. Epub 2019 Jan 22.


Hookworm-Derived Metabolites Suppress Pathology in a Mouse Model of Colitis and Inhibit Secretion of Key Inflammatory Cytokines in Primary Human Leukocytes.

Wangchuk P, Shepherd C, Constantinoiu C, Ryan RYM, Kouremenos KA, Becker L, Jones L, Buitrago G, Giacomin P, Wilson D, Daly N, McConville MJ, Miles JJ, Loukas A.

Infect Immun. 2019 Mar 25;87(4). pii: e00851-18. doi: 10.1128/IAI.00851-18. Print 2019 Apr.


Development of the Mitochondrial Intermembrane Space Disulfide Relay Represents a Critical Step in Eukaryotic Evolution.

Backes S, Garg SG, Becker L, Peleh V, Glockshuber R, Gould SB, Herrmann JM.

Mol Biol Evol. 2019 Apr 1;36(4):742-756. doi: 10.1093/molbev/msz011.


Measuring and Interpreting Oxygen Consumption Rates in Whole Fly Head Segments.

Dietz LJ, Venkatasubramani AV, Müller-Eigner A, Hrabe de Angelis M, Imhof A, Becker L, Peleg S.

J Vis Exp. 2019 Jan 7;(143). doi: 10.3791/58601.


Enhanced Macrophage Pannexin 1 Expression and Hemichannel Activation Exacerbates Lethal Experimental Sepsis.

Chen W, Zhu S, Wang Y, Li J, Qiang X, Zhao X, Yang H, D'Angelo J, Becker L, Wang P, Tracey KJ, Wang H.

Sci Rep. 2019 Jan 17;9(1):160. doi: 10.1038/s41598-018-37232-z.


Iron for the treatment of restless legs syndrome.

Trotti LM, Becker LA.

Cochrane Database Syst Rev. 2019 Jan 4;1:CD007834. doi: 10.1002/14651858.CD007834.pub3.


Genome-Wide Association Transethnic Meta-Analyses Identifies Novel Associations Regulating Coagulation Factor VIII and von Willebrand Factor Plasma Levels.

Sabater-Lleal M, Huffman JE, de Vries PS, Marten J, Mastrangelo MA, Song C, Pankratz N, Ward-Caviness CK, Yanek LR, Trompet S, Delgado GE, Guo X, Bartz TM, Martinez-Perez A, Germain M, de Haan HG, Ozel AB, Polasek O, Smith AV, Eicher JD, Reiner AP, Tang W, Davies NM, Stott DJ, Rotter JI, Tofler GH, Boerwinkle E, de Maat MPM, Kleber ME, Welsh P, Brody JA, Chen MH, Vaidya D, Soria JM, Suchon P, van Hylckama Vlieg A, Desch KC, Kolcic I, Joshi PK, Launer LJ, Harris TB, Campbell H, Rudan I, Becker DM, Li JZ, Rivadeneira F, Uitterlinden AG, Hofman A, Franco OH, Cushman M, Psaty BM, Morange PE, McKnight B, Chong MR, Fernandez-Cadenas I, Rosand J, Lindgren A; INVENT Consortium; MEGASTROKE Consortium of the International Stroke Genetics Consortium (ISGC), Gudnason V, Wilson JF, Hayward C, Ginsburg D, Fornage M, Rosendaal FR, Souto JC, Becker LC, Jenny NS, März W, Jukema JW, Dehghan A, Trégouët DA, Morrison AC, Johnson AD, O'Donnell CJ, Strachan DP, Lowenstein CJ, Smith NL.

Circulation. 2019 Jan 29;139(5):620-635. doi: 10.1161/CIRCULATIONAHA.118.034532.


Age-Related Changes in Gut Microbiota Alter Phenotype of Muscularis Macrophages and Disrupt Gastrointestinal Motility.

Becker L, Spear ET, Sinha SR, Haileselassie Y, Habtezion A.

Cell Mol Gastroenterol Hepatol. 2019;7(1):243-245.e2. doi: 10.1016/j.jcmgh.2018.09.001. Epub 2018 Sep 17. No abstract available.


Identification of Embryonic Neural Plate Border Stem Cells and Their Generation by Direct Reprogramming from Adult Human Blood Cells.

Thier MC, Hommerding O, Panten J, Pinna R, García-González D, Berger T, Wörsdörfer P, Assenov Y, Scognamiglio R, Przybylla A, Kaschutnig P, Becker L, Milsom MD, Jauch A, Utikal J, Herrmann C, Monyer H, Edenhofer F, Trumpp A.

Cell Stem Cell. 2019 Jan 3;24(1):166-182.e13. doi: 10.1016/j.stem.2018.11.015. Epub 2018 Dec 20.


A mouse model for intellectual disability caused by mutations in the X-linked 2'‑O‑methyltransferase Ftsj1 gene.

Jensen LR, Garrett L, Hölter SM, Rathkolb B, Rácz I, Adler T, Prehn C, Hans W, Rozman J, Becker L, Aguilar-Pimentel JA, Puk O, Moreth K, Dopatka M, Walther DJ, von Bohlen Und Halbach V, Rath M, Delatycki M, Bert B, Fink H, Blümlein K, Ralser M, Van Dijck A, Kooy F, Stark Z, Müller S, Scherthan H, Gecz J, Wurst W, Wolf E, Zimmer A, Klingenspor M, Graw J, Klopstock T, Busch D, Adamski J, Fuchs H, Gailus-Durner V, de Angelis MH, von Bohlen Und Halbach O, Ropers HH, Kuss AW.

Biochim Biophys Acta Mol Basis Dis. 2018 Dec 14. pii: S0925-4439(18)30497-6. doi: 10.1016/j.bbadis.2018.12.011. [Epub ahead of print]


A DNA-based fluorescent reporter maps HOCl production in the maturing phagosome.

Thekkan S, Jani MS, Cui C, Dan K, Zhou G, Becker L, Krishnan Y.

Nat Chem Biol. 2018 Dec 10. doi: 10.1038/s41589-018-0176-3. [Epub ahead of print]


Evidence-based decision making and promotion of physical activity among directors of local health departments.

Becker LA, Rech CR, Hino AAF, Reis RS.

Rev Saude Publica. 2018 Nov 23;52:90. doi: 10.11606/S1518-8787.2018052000379. English, Portuguese.


Increased access to urgent care centers decreases low acuity diagnoses in a nearby hospital emergency department.

Llovera I, Loscalzo K, Gao J, Li T, Brave M, Becker L, Barata I.

Am J Emerg Med. 2019 Mar;37(3):486-488. doi: 10.1016/j.ajem.2018.11.023. Epub 2018 Nov 17.


Molecular insights into genome-wide association studies of chronic kidney disease-defining traits.

Xu X, Eales JM, Akbarov A, Guo H, Becker L, Talavera D, Ashraf F, Nawaz J, Pramanik S, Bowes J, Jiang X, Dormer J, Denniff M, Antczak A, Szulinska M, Wise I, Prestes PR, Glyda M, Bogdanski P, Zukowska-Szczechowska E, Berzuini C, Woolf AS, Samani NJ, Charchar FJ, Tomaszewski M.

Nat Commun. 2018 Nov 22;9(1):4800. doi: 10.1038/s41467-018-07260-4.


Thyroid hormone levels and temperature during development alter thermal tolerance and energetics of Xenopus laevis larvae.

Ruthsatz K, Dausmann KH, Peck MA, Drees C, Sabatino NM, Becker LI, Reese J, Hartmann L, Glos J.

Conserv Physiol. 2018 Nov 17;6(1):coy059. doi: 10.1093/conphys/coy059. eCollection 2018.


A neurodegenerative-disease protein forms beneficial aggregates in healthy muscle.

Becker LA, Gitler AD.

Nature. 2018 Nov;563(7732):477-478. doi: 10.1038/d41586-018-07141-2. No abstract available.


Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.

Schnerwitzki D, Perry S, Ivanova A, Caixeta FV, Cramer P, Günther S, Weber K, Tafreshiha A, Becker L, Vargas Panesso IL, Klopstock T, Hrabe de Angelis M, Schmidt M, Kullander K, Englert C.

Life Sci Alliance. 2018 Aug 16;1(4):e201800106. doi: 10.26508/lsa.201800106. eCollection 2018 Aug.


Hypertension Is Associated with White Matter Disruption in Apparently Healthy Middle-Aged Individuals.

Hannawi Y, Yanek LR, Kral BG, Vaidya D, Becker LC, Becker DM, Nyquist PA.

AJNR Am J Neuroradiol. 2018 Dec;39(12):2243-2248. doi: 10.3174/ajnr.A5871. Epub 2018 Nov 15.


Activity and expression of E-NTPDase is altered in peripheral lymphocytes of systemic lupus erythematosus patients.

Becker LV, da Silva Pereira Saccol R, Morsch VM, Leal DBR, Casali EA, Lopes NGM, Cardoso VV, Schetinger MRC.

Clin Chim Acta. 2019 Jan;488:90-97. doi: 10.1016/j.cca.2018.10.032. Epub 2018 Oct 25.


Evidence for a Role of ACTN3 R577X Polymorphism in Football Player's Career Progression.

Coelho DB, Pimenta EM, Rosse IC, de Castro BM, Becker LK, de Oliveira EC, Carvalho MRS, Garcia ES.

Int J Sports Med. 2018 Dec;39(14):1088-1093. doi: 10.1055/a-0753-4973. Epub 2018 Nov 6.


Advances in Enteric Neurobiology: The "Brain" in the Gut in Health and Disease.

Kulkarni S, Ganz J, Bayrer J, Becker L, Bogunovic M, Rao M.

J Neurosci. 2018 Oct 31;38(44):9346-9354. doi: 10.1523/JNEUROSCI.1663-18.2018.


Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation.

Moskowitz A, Andersen LW, Huang DT, Berg KM, Grossestreuer AV, Marik PE, Sherwin RL, Hou PC, Becker LB, Cocchi MN, Doshi P, Gong J, Sen A, Donnino MW.

Crit Care. 2018 Oct 29;22(1):283. doi: 10.1186/s13054-018-2217-4. Review.


Sustained prognostic impact of circulating tumor cell status and kinetics upon further progression of metastatic breast cancer.

Jauch SF, Riethdorf S, Sprick MR, Schütz F, Schönfisch B, Brucker SY, Deutsch TM, Nees J, Saini M, Becker LM, Burwinkel B, Sinn P, Marmé F, Pantel K, Jäger D, Sohn C, Trumpp A, Wallwiener M, Schneeweiss A.

Breast Cancer Res Treat. 2019 Jan;173(1):155-165. doi: 10.1007/s10549-018-4972-y. Epub 2018 Oct 1.


Lymphatic Filariasis Increases Tissue Compressibility and Extracellular Fluid in Lower Limbs of Asymptomatic Young People in Central Myanmar.

Douglass J, Graves P, Lindsay D, Becker L, Roineau M, Masson J, Aye NN, Win SS, Wai T, Win YY, Gordon S.

Trop Med Infect Dis. 2017 Sep 27;2(4). pii: E50. doi: 10.3390/tropicalmed2040050.


Diabetes and Platelet Response to Low-Dose Aspirin.

Al-Sofiani ME, Yanek LR, Faraday N, Kral BG, Mathias R, Becker LC, Becker DM, Vaidya D, Kalyani RR.

J Clin Endocrinol Metab. 2018 Dec 1;103(12):4599-4608. doi: 10.1210/jc.2018-01254.


Gallium disrupts bacterial iron metabolism and has therapeutic effects in mice and humans with lung infections.

Goss CH, Kaneko Y, Khuu L, Anderson GD, Ravishankar S, Aitken ML, Lechtzin N, Zhou G, Czyz DM, McLean K, Olakanmi O, Shuman HA, Teresi M, Wilhelm E, Caldwell E, Salipante SJ, Hornick DB, Siehnel RJ, Becker L, Britigan BE, Singh PK.

Sci Transl Med. 2018 Sep 26;10(460). pii: eaat7520. doi: 10.1126/scitranslmed.aat7520.


An effort toward molecular biology of food deprivation induced food hoarding in gonadectomized NMRI mouse model: focus on neural oxidative status.

Nikray N, Karimi I, Siavashhaghighi Z, Becker LA, Mofatteh MM.

BMC Neurosci. 2018 Sep 24;19(1):59. doi: 10.1186/s12868-018-0461-9.


[Optimization of criteria for activation of trauma teams : Avoidance of overtriage and undertriage].

Bieler D, Trentzsch H, Baacke M, Becker L, Düsing H, Heindl B, Jensen KO, Lefering R, Mand C, Özkurtul O, Paffrath T, Schweigkofler U, Sprengel K, Wohlrath B, Waydhas C.

Unfallchirurg. 2018 Oct;121(10):788-793. doi: 10.1007/s00113-018-0553-0. Review. German.


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