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Items: 1 to 50 of 513

1.

S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma (cSCC) - short version, part 2: epidemiology, surgical and systemic treatment of cSCC, follow-up, prevention and occupational disease.

Leiter U, Heppt MV, Steeb T, Amaral T, Bauer A, Becker JC, Breitbart E, Breuninger H, Diepgen T, Dirschka T, Eigentler T, Flaig M, Follmann M, Fritz K, Greinert R, Gutzmer R, Hillen U, Ihrler S, John SM, Kölbl O, Kraywinkel K, Löser C, Nashan D, Noor S, Nothacker M, Pfannenberg C, Salavastru C, Schmitz L, Stockfleth E, Szeimies RM, Ulrich C, Welzel J, Wermker K, Garbe C, Berking C.

J Dtsch Dermatol Ges. 2020 Apr 4. doi: 10.1111/ddg.14072. [Epub ahead of print]

PMID:
32247292
2.

Expression of Programmed Cell Death Proteins in Kaposi Sarcoma and Cutaneous Angiosarcoma.

Gambichler T, Koim S, Wrobel M, Käfferlein HU, Brüning T, Stockfleth E, Becker JC, Lang K.

J Immunother. 2020 Mar 27. doi: 10.1097/CJI.0000000000000317. [Epub ahead of print]

PMID:
32224717
3.

Survival of patients with advanced metastatic melanoma: The impact of MAP kinase pathway inhibition and immune checkpoint inhibition - Update 2019.

Ugurel S, Röhmel J, Ascierto PA, Becker JC, Flaherty KT, Grob JJ, Hauschild A, Larkin J, Livingstone E, Long GV, Lorigan P, McArthur GA, Ribas A, Robert C, Zimmer L, Schadendorf D, Garbe C.

Eur J Cancer. 2020 Mar 13;130:126-138. doi: 10.1016/j.ejca.2020.02.021. [Epub ahead of print]

PMID:
32179447
4.

S3 guideline for actinic keratosis and cutaneous squamous cell carcinoma - short version, part 1: diagnosis, interventions for actinic keratoses, care structures and quality-of-care indicators.

Heppt MV, Leiter U, Steeb T, Amaral T, Bauer A, Becker JC, Breitbart E, Breuninger H, Diepgen T, Dirschka T, Eigentler T, Flaig M, Follmann M, Fritz K, Greinert R, Gutzmer R, Hillen U, Ihrler S, John SM, Kölbl O, Kraywinkel K, Löser C, Nashan D, Noor S, Nothacker M, Pfannenberg C, Salavastru C, Schmitz L, Stockfleth E, Szeimies RM, Ulrich C, Welzel J, Wermker K, Berking C, Garbe C.

J Dtsch Dermatol Ges. 2020 Mar;18(3):275-294. doi: 10.1111/ddg.14048.

PMID:
32130773
5.

S3-Leitlinie „Aktinische Keratose und Plattenepithelkarzinom der Haut“ - Kurzfassung, Teil 1: Diagnostik, Interventionen bei aktinischen Keratosen, Versorgungsstrukturen und Qualitätsindikatoren.

Heppt MV, Leiter U, Steeb T, Amaral T, Bauer A, Becker JC, Breitbart E, Breuninger H, Diepgen T, Dirschka T, Eigentler T, Flaig M, Follmann M, Fritz K, Greinert R, Gutzmer R, Hillen U, Ihrler S, John SM, Kölbl O, Kraywinkel K, Löser C, Nashan D, Noor S, Nothacker M, Pfannenberg C, Salavastru C, Schmitz L, Stockfleth E, Szeimies RM, Ulrich C, Welzel J, Wermker K, Berking C, Garbe C.

J Dtsch Dermatol Ges. 2020 Mar;18(3):275-294. doi: 10.1111/ddg.14048_g. German.

PMID:
32130769
6.

Molecular Profiling of Keratinocyte Skin Tumors Links Staphylococcus aureus Overabundance and Increased Human β-Defensin-2 Expression to Growth Promotion of Squamous Cell Carcinoma.

Madhusudhan N, Pausan MR, Halwachs B, Durdević M, Windisch M, Kehrmann J, Patra V, Wolf P, Boukamp P, Moissl-Eichinger C, Cerroni L, Becker JC, Gorkiewicz G.

Cancers (Basel). 2020 Feb 26;12(3). pii: E541. doi: 10.3390/cancers12030541.

7.

Highly Expressed miR-375 is not an Intracellular Oncogene in Merkel Cell Polyomavirus-Associated Merkel Cell Carcinoma.

Fan K, Zebisch A, Horny K, Schrama D, Becker JC.

Cancers (Basel). 2020 Feb 25;12(3). pii: E529. doi: 10.3390/cancers12030529.

8.

A Decade of Experience with the Ovine Model of Myelomeningocele: Risk Factors for Fetal Loss.

Galganski LA, Yamashiro KJ, Pivetti CD, Keller BA, Becker JC, Brown EG, Saadai P, Hirose S, Wang A, Farmer DL.

Fetal Diagn Ther. 2020 Feb 25:1-7. doi: 10.1159/000505400. [Epub ahead of print]

PMID:
32097922
9.

Expression of Lefty predicts Merkel cell carcinoma-specific death.

Gambichler T, Ardabili S, Dreißigacker M, Scheel CH, Brand-Saberi B, Skrygan M, Stockfleth E, Becker JC.

J Eur Acad Dermatol Venereol. 2020 Feb 5. doi: 10.1111/jdv.16271. [Epub ahead of print]

PMID:
32022949
10.

Clamping trials prior to thoracostomy tube removal and the need for subsequent invasive pleural drainage.

Becker JC, Zakaluzny SA, Keller BA, Galante JM, Utter GH.

Am J Surg. 2020 Jan 8. pii: S0002-9610(20)30008-8. doi: 10.1016/j.amjsurg.2020.01.007. [Epub ahead of print]

PMID:
31948700
11.

Predominance of Central Memory T Cells with High T-Cell Receptor Repertoire Diversity is Associated with Response to PD-1/PD-L1 Inhibition in Merkel Cell Carcinoma.

Spassova I, Ugurel S, Terheyden P, Sucker A, Hassel JC, Ritter C, Kubat L, Habermann D, Farahpour F, Saeedghalati M, Peiffer L, Kumar R, Schrama D, Hoffmann D, Schadendorf D, Becker JC.

Clin Cancer Res. 2020 Jan 13. doi: 10.1158/1078-0432.CCR-19-2244. [Epub ahead of print]

PMID:
31932494
12.

Elevated baseline serum PD-1 or PD-L1 predicts poor outcome of PD-1 inhibition therapy in metastatic melanoma.

Ugurel S, Schadendorf D, Horny K, Sucker A, Schramm S, Utikal J, Pföhler C, Herbst R, Schilling B, Blank C, Becker JC, Paschen A, Zimmer L, Livingstone E, Horn PA, Rebmann V.

Ann Oncol. 2020 Jan;31(1):144-152. doi: 10.1016/j.annonc.2019.09.005.

PMID:
31912789
13.

Dicer Sequencing, Whole Genome Methylation Profiling, mRNA and smallRNA Sequencing Analysis in Basal Cell Carcinoma.

Sand M, Bromba A, Sand D, Gambichler T, Hessam S, Becker JC, Stockfleth E, Meyer T, Bechara FG.

Cell Physiol Biochem. 2019;53(5):760-773. doi: 10.33594/000000171.

14.

Staphylococcal alpha-toxin tilts the balance between malignant and non-malignant CD4+ T cells in cutaneous T-cell lymphoma.

Blümel E, Willerslev-Olsen A, Gluud M, Lindahl LM, Fredholm S, Nastasi C, Krejsgaard T, Surewaard BGJ, Koralov SB, Hu T, Persson JL, Bonefeld CM, Geisler C, Iversen L, Becker JC, Andersen MH, Woetmann A, Buus TB, Ødum N.

Oncoimmunology. 2019 Jul 17;8(11):e1641387. doi: 10.1080/2162402X.2019.1641387. eCollection 2019.

15.

Neues zum kutanen Plattenepithelkarzinom.

Gutzmer R, Becker JC.

J Dtsch Dermatol Ges. 2019 Oct;17(10):1097-1098. doi: 10.1111/ddg.13949_g. German. No abstract available.

PMID:
31631551
16.

The Harmful Side of Thanks: Thankful Responses to High-Power Group Help Undermine Low-Power Groups' Protest.

Ksenofontov I, Becker JC.

Pers Soc Psychol Bull. 2019 Oct 9:146167219879125. doi: 10.1177/0146167219879125. [Epub ahead of print]

PMID:
31597516
17.

Conversion of Sox2-dependent Merkel cell carcinoma to a differentiated neuron-like phenotype by T antigen inhibition.

Harold A, Amako Y, Hachisuka J, Bai Y, Li MY, Kubat L, Gravemeyer J, Franks J, Gibbs JR, Park HJ, Ezhkova E, Becker JC, Shuda M.

Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):20104-20114. doi: 10.1073/pnas.1907154116. Epub 2019 Sep 16.

18.

A phase II study of the L19IL2 immunocytokine in combination with dacarbazine in advanced metastatic melanoma patients.

Weide B, Eigentler T, Catania C, Ascierto PA, Cascinu S, Becker JC, Hauschild A, Romanini A, Danielli R, Dummer R, Trefzer U, Elia G, Neri D, Garbe C.

Cancer Immunol Immunother. 2019 Sep;68(9):1547-1559. doi: 10.1007/s00262-019-02383-z. Epub 2019 Sep 3.

PMID:
31482307
19.

Decline of programmed death-1-positive circulating T regulatory cells predicts more favourable clinical outcome of patients with melanoma under immune checkpoint blockade.

Gambichler T, Schröter U, Höxtermann S, Susok L, Stockfleth E, Becker JC.

Br J Dermatol. 2019 Jul 30. doi: 10.1111/bjd.18379. [Epub ahead of print]

PMID:
31361026
20.

Antibiotics inhibit tumor and disease activity in cutaneous T-cell lymphoma.

Lindahl LM, Willerslev-Olsen A, Gjerdrum LMR, Nielsen PR, Blümel E, Rittig AH, Celis P, Herpers B, Becker JC, Stausbøl-Grøn B, Wasik MA, Gluud M, Fredholm S, Buus TB, Johansen C, Nastasi C, Peiffer L, Kubat L, Bzorek M, Eriksen JO, Krejsgaard T, Bonefeld CM, Geisler C, Mustelin T, Langhoff E, Givskov M, Woetmann A, Kilian M, Litman T, Iversen L, Odum N.

Blood. 2019 Sep 26;134(13):1072-1083. doi: 10.1182/blood.2018888107. Epub 2019 Jul 22.

PMID:
31331920
21.

Successful integration of radiation oncology in preclinical medical education : Experiences with an interdisciplinary training project.

Oertel M, Schmitz M, Becker JC, Eich HT, Schober A.

Strahlenther Onkol. 2019 Dec;195(12):1104-1109. doi: 10.1007/s00066-019-01492-z. Epub 2019 Jul 15.

PMID:
31309265
22.

MCPyV Large T Antigen-Induced Atonal Homolog 1 Is a Lineage-Dependency Oncogene in Merkel Cell Carcinoma.

Fan K, Gravemeyer J, Ritter C, Rasheed K, Gambichler T, Moens U, Shuda M, Schrama D, Becker JC.

J Invest Dermatol. 2020 Jan;140(1):56-65.e3. doi: 10.1016/j.jid.2019.06.135. Epub 2019 Jul 5.

PMID:
31283928
23.

MERTK Acts as a Costimulatory Receptor on Human CD8+ T Cells.

Peeters MJW, Dulkeviciute D, Draghi A, Ritter C, Rahbech A, Skadborg SK, Seremet T, Carnaz Simões AM, Martinenaite E, Halldórsdóttir HR, Andersen MH, Olofsson GH, Svane IM, Rasmussen LJ, Met Ö, Becker JC, Donia M, Desler C, Thor Straten P.

Cancer Immunol Res. 2019 Sep;7(9):1472-1484. doi: 10.1158/2326-6066.CIR-18-0841. Epub 2019 Jul 2.

PMID:
31266785
24.

Uveal Melanoma: A European Network to Face the Many Challenges of a Rare Cancer.

Piperno-Neumann S, Piulats JM, Goebeler M, Galloway I, Lugowska I, Becker JC, Vihinen P, Van Calster J, Hadjistilianou T, Proença R, Caminal JM, Rogasik M, Blay JY, Kapiteijn E.

Cancers (Basel). 2019 Jun 13;11(6). pii: E817. doi: 10.3390/cancers11060817.

25.

Combination of denosumab and immune checkpoint inhibition: experience in 29 patients with metastatic melanoma and bone metastases.

Angela Y, Haferkamp S, Weishaupt C, Ugurel S, Becker JC, Oberndörfer F, Alar V, Satzger I, Gutzmer R.

Cancer Immunol Immunother. 2019 Jul;68(7):1187-1194. doi: 10.1007/s00262-019-02353-5. Epub 2019 Jun 11.

PMID:
31187176
26.

A Brief Communication on Circulating PD-1-positive T-Regulatory Lymphocytes in Melanoma Patients Undergoing Adjuvant Immunotherapy With Nivolumab.

Gambichler T, Schröter U, Höxtermann S, Susok L, Stockfleth E, Becker JC.

J Immunother. 2019 Sep;42(7):265-268. doi: 10.1097/CJI.0000000000000277.

PMID:
31145230
27.

Merkel Cell Carcinoma of the Head in a Young African Albino Woman with HIV/HTLV-1 Coinfection Associated with Multiple Squamous Cell Carcinomas.

Tenea D, Dinkel J, Becker JC, van der Walt E.

Case Rep Dermatol. 2019 Apr 30;11(1):113-122. doi: 10.1159/000499898. eCollection 2019 Jan-Apr.

28.

Metastatic Merkel cell carcinoma and myasthenia gravis: contraindication for therapy with immune checkpoint inhibitors?

Zaremba A, Chorti E, Jockenhöfer F, Bolz S, Sirin S, Glas M, Becker JC, Ugurel S, Roesch A, Schadendorf D, Livingstone E, Hagenacker T, Zimmer L.

J Immunother Cancer. 2019 May 29;7(1):141. doi: 10.1186/s40425-019-0626-9.

29.

Thin Media Images Decrease Women's Body Satisfaction: Comparisons Between Veiled Muslim Women, Christian Women and Atheist Women Regarding Trait and State Body Image.

Wilhelm L, Hartmann AS, Becker JC, Kisi M, Waldorf M, Vocks S.

Front Psychol. 2019 May 10;10:1074. doi: 10.3389/fpsyg.2019.01074. eCollection 2019.

30.

S2k-Leitlinie Merkelzellkarzinom (MZK, MCC, neuroendokrines Karzinom der Haut) - Update 2018.

Becker JC, Eigentler T, Frerich B, Gambichler T, Grabbe S, Höller U, Klumpp B, Loquai C, Krause-Bergmann A, Müller-Richter U, Pföhler C, Schneider-Burrus S, Stang A, Terheyden P, Ugurel S, Veith J, Mauch C.

J Dtsch Dermatol Ges. 2019 May;17(5):562-577. doi: 10.1111/ddg.13841_g.

PMID:
31115985
31.

S2k guidelines for Merkel cell carcinoma (MCC, neuroendocrine carcinoma of the skin) - update 2018.

Becker JC, Eigentler T, Frerich B, Gambichler T, Grabbe S, Höller U, Klumpp B, Loquai C, Krause-Bergmann A, Müller-Richter U, Pföhler C, Schneider-Burrus S, Stang A, Terheyden P, Ugurel S, Veith J, Mauch C.

J Dtsch Dermatol Ges. 2019 May;17(5):562-576. doi: 10.1111/ddg.13841. Epub 2019 May 6.

PMID:
31056838
32.

Identification of genes under dynamic post-transcriptional regulation from time-series epigenomic data.

Becker JC, Gérard D, Ginolhac A, Sauter T, Sinkkonen L.

Epigenomics. 2019 May;11(6):619-638. doi: 10.2217/epi-2018-0084. Epub 2019 May 2.

33.

MHC class-I downregulation in PD-1/PD-L1 inhibitor refractory Merkel cell carcinoma and its potential reversal by histone deacetylase inhibition: a case series.

Ugurel S, Spassova I, Wohlfarth J, Drusio C, Cherouny A, Melior A, Sucker A, Zimmer L, Ritter C, Schadendorf D, Becker JC.

Cancer Immunol Immunother. 2019 Jun;68(6):983-990. doi: 10.1007/s00262-019-02341-9. Epub 2019 Apr 16.

PMID:
30993371
34.

HDAC8 Regulates a Stress Response Pathway in Melanoma to Mediate Escape from BRAF Inhibitor Therapy.

Emmons MF, Faião-Flores F, Sharma R, Thapa R, Messina JL, Becker JC, Schadendorf D, Seto E, Sondak VK, Koomen JM, Chen YA, Lau EK, Wan L, Licht JD, Smalley KSM.

Cancer Res. 2019 Jun 1;79(11):2947-2961. doi: 10.1158/0008-5472.CAN-19-0040. Epub 2019 Apr 15.

PMID:
30987999
35.

Characterization of six Merkel cell polyomavirus-positive Merkel cell carcinoma cell lines: Integration pattern suggest that large T antigen truncating events occur before or during integration.

Schrama D, Sarosi EM, Adam C, Ritter C, Kaemmerer U, Klopocki E, König EM, Utikal J, Becker JC, Houben R.

Int J Cancer. 2019 Aug 15;145(4):1020-1032. doi: 10.1002/ijc.32280. Epub 2019 Apr 4.

PMID:
30873613
36.

A medium-throughput screen for inhibitors of human metapneumovirus.

Becker JC, Tollefson SJ, Weaver D, Williams JV.

Antivir Chem Chemother. 2019 Jan-Dec;27:2040206619830197. doi: 10.1177/2040206619830197.

37.

Neuroprotective effect of placenta-derived mesenchymal stromal cells: role of exosomes.

Kumar P, Becker JC, Gao K, Carney RP, Lankford L, Keller BA, Herout K, Lam KS, Farmer DL, Wang A.

FASEB J. 2019 May;33(5):5836-5849. doi: 10.1096/fj.201800972R. Epub 2019 Feb 12.

38.

Decreased 5-hydroxymethylcytosine immunoreactivity in primary Merkel cell carcinoma is a strong predictor for disease-specific death.

Gambichler T, Schmitt K, Rüddel I, Dreibigacker M, Stockfleth E, Becker JC.

Br J Dermatol. 2019 Aug;181(2):389-390. doi: 10.1111/bjd.17705. Epub 2019 Apr 23. No abstract available.

PMID:
30703276
39.

[Merkel cell carcinoma].

Drusio C, Becker JC, Schadendorf D, Ugurel S.

Hautarzt. 2019 Mar;70(3):215-227. doi: 10.1007/s00105-019-4360-5. German.

PMID:
30701288
40.

[Implementation and evaluation of a revised curriculum for psychiatry and psychotherapy].

Koelkebeck K, Brouwer B, Ahrens H, Becker JC, Weih M, Marschall B, Arolt V, Ohrmann P.

Nervenarzt. 2019 Nov;90(11):1170-1176. doi: 10.1007/s00115-019-0677-7. German.

PMID:
30694367
41.

Genomic Landscape of Spitzoid Neoplasms Impacting Patient Management.

Hillen LM, Van den Oord J, Geybels MS, Becker JC, Zur Hausen A, Winnepenninckx V.

Front Med (Lausanne). 2018 Dec 13;5:344. doi: 10.3389/fmed.2018.00344. eCollection 2018. Review.

42.

T cell receptor fingerprinting enables in-depth characterization of the interactions governing recognition of peptide-MHC complexes.

Bentzen AK, Such L, Jensen KK, Marquard AM, Jessen LE, Miller NJ, Church CD, Lyngaa R, Koelle DM, Becker JC, Linnemann C, Schumacher TNM, Marcatili P, Nghiem P, Nielsen M, Hadrup SR.

Nat Biotechnol. 2018 Nov 19. doi: 10.1038/nbt.4303. [Epub ahead of print]

PMID:
30451992
43.

A single-arm, open-label study to assess the immunogenicity, safety, and efficacy of etanercept manufactured using the serum-free, high-capacity manufacturing process administered to patients with rheumatoid arthritis.

Polák P, Peric P, Louw I, Gaylord SM, Williams T, Becker JC, Pedersen R, Korth-Bradley J, Vlahos B.

Eur J Rheumatol. 2019 Jan;6(1):23-28. doi: 10.5152/eurjrheum.2018.18078.

44.

Pharmacological Inhibition of Serine Palmitoyl Transferase and Sphingosine Kinase-1/-2 Inhibits Merkel Cell Carcinoma Cell Proliferation.

Bhat VK, Bernhart E, Plastira I, Fan K, Ghaffari-Tabrizi-Wizsy N, Wadsack C, Rechberger G, Eichmann T, Asslaber M, Spassova I, Verhaegen ME, Malle E, Becker JC, Sattler W.

J Invest Dermatol. 2019 Apr;139(4):807-817. doi: 10.1016/j.jid.2018.10.024. Epub 2018 Nov 3.

PMID:
30399362
45.

Development and initial Experience of an online Exchange Platform on Sex and Gender Aspects in Medicine: "GenderMed-Wiki".

Schreitmüller J, Becker JC, Zsebedits D, Weskott M, Dehghan-Nayyeri M, Fegeler C, Heue M, Hochleitner M, Kindler-Röhrborn A, Pfleiderer B.

GMS J Med Educ. 2018 Aug 15;35(3):Doc32. doi: 10.3205/zma001178. eCollection 2018.

46.

Experimental Studies on State Self-Objectification: A Review and an Integrative Process Model.

Kahalon R, Shnabel N, Becker JC.

Front Psychol. 2018 Aug 13;9:1268. doi: 10.3389/fpsyg.2018.01268. eCollection 2018. Review.

47.

Molecular profiling of Spitz nevi identified by digital RNA counting.

Hillen LM, Geybels MS, Rennspiess D, Spassova I, Ritter C, Becker JC, Garmyn M, Zur Hausen A, Van den Oord J, Winnepenninckx V.

Melanoma Res. 2018 Dec;28(6):510-520. doi: 10.1097/CMR.0000000000000495.

48.

Circulating Cell-Free miR-375 as Surrogate Marker of Tumor Burden in Merkel Cell Carcinoma.

Fan K, Ritter C, Nghiem P, Blom A, Verhaegen ME, Dlugosz A, Ødum N, Woetmann A, Tothill RW, Hicks RJ, Sand M, Schrama D, Schadendorf D, Ugurel S, Becker JC.

Clin Cancer Res. 2018 Dec 1;24(23):5873-5882. doi: 10.1158/1078-0432.CCR-18-1184. Epub 2018 Jul 30.

49.

Relational mobility predicts social behaviors in 39 countries and is tied to historical farming and threat.

Thomson R, Yuki M, Talhelm T, Schug J, Kito M, Ayanian AH, Becker JC, Becker M, Chiu CY, Choi HS, Ferreira CM, Fülöp M, Gul P, Houghton-Illera AM, Joasoo M, Jong J, Kavanagh CM, Khutkyy D, Manzi C, Marcinkowska UM, Milfont TL, Neto F, von Oertzen T, Pliskin R, San Martin A, Singh P, Visserman ML.

Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):7521-7526. doi: 10.1073/pnas.1713191115. Epub 2018 Jun 29. Erratum in: Proc Natl Acad Sci U S A. 2019 Apr 16;116(16):8082.

50.

SATB1 in Malignant T Cells.

Fredholm S, Willerslev-Olsen A, Met Ö, Kubat L, Gluud M, Mathiasen SL, Friese C, Blümel E, Petersen DL, Hu T, Nastasi C, Lindahl LM, Buus TB, Krejsgaard T, Wasik MA, Kopp KL, Koralov SB, Persson JL, Bonefeld CM, Geisler C, Woetmann A, Iversen L, Becker JC, Ødum N.

J Invest Dermatol. 2018 Aug;138(8):1805-1815. doi: 10.1016/j.jid.2018.03.1526. Epub 2018 May 8.

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