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Items: 1 to 50 of 241

1.

Isomorphic diffuse glioma is a morphologically and molecularly distinct tumour entity with recurrent gene fusions of MYBL1 or MYB and a benign disease course.

Wefers AK, Stichel D, Schrimpf D, Coras R, Pages M, Tauziède-Espariat A, Varlet P, Schwarz D, Söylemezoglu F, Pohl U, Pimentel J, Meyer J, Hewer E, Japp A, Joshi A, Reuss DE, Reinhardt A, Sievers P, Casalini MB, Ebrahimi A, Huang K, Koelsche C, Low HL, Rebelo O, Marnoto D, Becker AJ, Staszewski O, Mittelbronn M, Hasselblatt M, Schittenhelm J, Cheesman E, de Oliveira RS, Queiroz RGP, Valera ET, Hans VH, Korshunov A, Olar A, Ligon KL, Pfister SM, Jaunmuktane Z, Brandner S, Tatevossian RG, Ellison DW, Jacques TS, Honavar M, Aronica E, Thom M, Sahm F, von Deimling A, Jones DTW, Blumcke I, Capper D.

Acta Neuropathol. 2019 Sep 28. doi: 10.1007/s00401-019-02078-w. [Epub ahead of print]

PMID:
31563982
2.

Long-term adult human brain slice cultures as a model system to study human CNS circuitry and disease.

Schwarz N, Uysal B, Welzer M, Bahr JC, Layer N, Löffler H, Stanaitis K, Pa H, Weber YG, Hedrich UB, Honegger JB, Skodras A, Becker AJ, Wuttke TV, Koch H.

Elife. 2019 Sep 9;8. pii: e48417. doi: 10.7554/eLife.48417.

3.

When does conscious memory become dependent on the hippocampus? The role of memory load and the differential relevance of left hippocampal integrity for short- and long-term aspects of verbal memory performance.

Witt JA, Coras R, Becker AJ, Elger CE, Blümcke I, Helmstaedter C.

Brain Struct Funct. 2019 May;224(4):1599-1607. doi: 10.1007/s00429-019-01857-1. Epub 2019 Mar 13.

PMID:
30863886
4.

Calcium Channel Subunit α2δ4 Is Regulated by Early Growth Response 1 and Facilitates Epileptogenesis.

van Loo KMJ, Rummel CK, Pitsch J, Müller JA, Bikbaev AF, Martinez-Chavez E, Blaess S, Dietrich D, Heine M, Becker AJ, Schoch S.

J Neurosci. 2019 Apr 24;39(17):3175-3187. doi: 10.1523/JNEUROSCI.1731-18.2019. Epub 2019 Feb 21.

PMID:
30792272
5.

No evidence for a BRD2 promoter hypermethylation in blood leukocytes of Europeans with juvenile myoclonic epilepsy.

Schulz H, Ruppert AK, Zara F, Madia F, Iacomino M, S Vari M, Balagura G, Minetti C, Striano P, Bianchi A, Marini C, Guerrini R, Weber YG, Becker F, Lerche H, Kapser C, Schankin CJ, Kunz WS, Møller RS, Oliver KL, Bellows ST, Mullen SA, Berkovic SF, Scheffer IE, Caglayan H, Ozbek U, Hoffmann P, Schramm S, Tsortouktzidis D, Becker AJ, Sander T.

Epilepsia. 2019 May;60(5):e31-e36. doi: 10.1111/epi.14657. Epub 2019 Feb 4.

PMID:
30719712
6.

Cancer frequency detected by positron emission tomography-computed tomography in limbic encephalitis.

Hansen N, Widman G, Stuff S, Becker AJ, Witt JA, Ahmadzadehfar H, Helmstaedter C, Elger CE.

Epilepsy Behav. 2018 Dec;89:105-111. doi: 10.1016/j.yebeh.2018.09.043. Epub 2018 Nov 6.

PMID:
30408704
7.

Precipitating events in child and adolescent chronic musculoskeletal pain.

Becker AJ, Heathcote LC, Timmers I, Simons LE.

Pain Rep. 2018 Sep 11;3(Suppl 1):e665. doi: 10.1097/PR9.0000000000000665. eCollection 2018 Sep.

8.

Course of transforming growth factor ß1 in the systemic and cavernous blood of healthy males through different penile conditions.

Rahardjo HE, Ückert S, Bannowsky A, Tsikas D, Becker AJ, Kuczyk MA.

Andrologia. 2019 Feb;51(1):e13150. doi: 10.1111/and.13150. Epub 2018 Sep 24.

PMID:
30251438
9.

Cognitive features and surgical outcome of patients with long-term epilepsy-associated tumors (LEATs) within the temporal lobe.

Vogt VL, Witt JA, Delev D, Grote A, von Lehe M, Becker AJ, Schramm J, Elger CE, Helmstaedter C.

Epilepsy Behav. 2018 Nov;88:25-32. doi: 10.1016/j.yebeh.2018.08.028. Epub 2018 Sep 10.

PMID:
30212725
10.

Anti-epileptogenic and Anti-convulsive Effects of Fingolimod in Experimental Temporal Lobe Epilepsy.

Pitsch J, Kuehn JC, Gnatkovsky V, Müller JA, van Loo KMJ, de Curtis M, Vatter H, Schoch S, Elger CE, Becker AJ.

Mol Neurobiol. 2019 Mar;56(3):1825-1840. doi: 10.1007/s12035-018-1181-y. Epub 2018 Jun 22.

PMID:
29934763
11.

Effects of Flow Disruptions on Mental Workload and Surgical Performance in Robotic-Assisted Surgery.

Weber J, Catchpole K, Becker AJ, Schlenker B, Weigl M.

World J Surg. 2018 Nov;42(11):3599-3607. doi: 10.1007/s00268-018-4689-4.

PMID:
29845381
12.

Is β-endorphin significant in the control of the male sexual response?

Ückert S, Becker AJ, Bannowsky A, Stief CG, Kuczyk MA.

Andrologia. 2018 Sep;50(7):e13049. doi: 10.1111/and.13049. Epub 2018 May 20.

PMID:
29781087
13.

New developments in understanding focal cortical malformations.

Becker AJ, Beck H.

Curr Opin Neurol. 2018 Apr;31(2):151-155. doi: 10.1097/WCO.0000000000000531. Review.

PMID:
29278549
14.

Pre- and long-term postoperative courses of hippocampus-associated memory impairment in epilepsy patients with antibody-associated limbic encephalitis and selective amygdalohippocampectomy.

Hansen N, Ernst L, Rüber T, Widman G, Becker AJ, Elger CE, Helmstaedter C.

Epilepsy Behav. 2018 Feb;79:93-99. doi: 10.1016/j.yebeh.2017.10.033. Epub 2017 Dec 16.

PMID:
29253681
15.

NMDAR encephalitis: passive transfer from man to mouse by a recombinant antibody.

Malviya M, Barman S, Golombeck KS, Planagumà J, Mannara F, Strutz-Seebohm N, Wrzos C, Demir F, Baksmeier C, Steckel J, Falk KK, Gross CC, Kovac S, Bönte K, Johnen A, Wandinger KP, Martín-García E, Becker AJ, Elger CE, Klöcker N, Wiendl H, Meuth SG, Hartung HP, Seebohm G, Leypoldt F, Maldonado R, Stadelmann C, Dalmau J, Melzer N, Goebels N.

Ann Clin Transl Neurol. 2017 Oct 3;4(11):768-783. doi: 10.1002/acn3.444. eCollection 2017 Nov.

16.

Large-scale analysis of herpesviridae in epilepsy-patients with signs of autoimmune encephalitis.

Poulheim F, Esposito L, Elger CE, Eis-Hübinger AM, Becker AJ, Niehusmann P.

Seizure. 2017 Dec;53:100-102. doi: 10.1016/j.seizure.2017.11.012. Epub 2017 Nov 16.

17.

Genome-wide mapping of genetic determinants influencing DNA methylation and gene expression in human hippocampus.

Schulz H, Ruppert AK, Herms S, Wolf C, Mirza-Schreiber N, Stegle O, Czamara D, Forstner AJ, Sivalingam S, Schoch S, Moebus S, Pütz B, Hillmer A, Fricker N, Vatter H, Müller-Myhsok B, Nöthen MM, Becker AJ, Hoffmann P, Sander T, Cichon S.

Nat Commun. 2017 Nov 15;8(1):1511. doi: 10.1038/s41467-017-01818-4.

18.

Review: Animal models of acquired epilepsy: insights into mechanisms of human epileptogenesis.

Becker AJ.

Neuropathol Appl Neurobiol. 2018 Feb;44(1):112-129. doi: 10.1111/nan.12451. Review.

PMID:
29130506
19.

TGFβ signaling is associated with changes in inflammatory gene expression and perineuronal net degradation around inhibitory neurons following various neurological insults.

Kim SY, Senatorov VV Jr, Morrissey CS, Lippmann K, Vazquez O, Milikovsky DZ, Gu F, Parada I, Prince DA, Becker AJ, Heinemann U, Friedman A, Kaufer D.

Sci Rep. 2017 Aug 9;7(1):7711. doi: 10.1038/s41598-017-07394-3.

20.

Heterogeneous contribution of microdeletions in the development of common generalised and focal epilepsies.

Pérez-Palma E, Helbig I, Klein KM, Anttila V, Horn H, Reinthaler EM, Gormley P, Ganna A, Byrnes A, Pernhorst K, Toliat MR, Saarentaus E, Howrigan DP, Hoffman P, Miquel JF, De Ferrari GV, Nürnberg P, Lerche H, Zimprich F, Neubauer BA, Becker AJ, Rosenow F, Perucca E, Zara F, Weber YG, Lal D.

J Med Genet. 2017 Sep;54(9):598-606. doi: 10.1136/jmedgenet-2016-104495. Epub 2017 Jul 29.

21.

Innate and adaptive immunity in human epilepsies.

Bauer J, Becker AJ, Elyaman W, Peltola J, Rüegg S, Titulaer MJ, Varley JA, Beghi E.

Epilepsia. 2017 Jul;58 Suppl 3:57-68. doi: 10.1111/epi.13784. Review.

22.

Development of In Vivo Imaging Tools for Investigating Astrocyte Activation in Epileptogenesis.

Kostoula C, Pascente R, Ravizza T, McCown T, Schoch S, Vezzani A, Becker AJ, van Loo KMJ.

Mol Neurobiol. 2018 May;55(5):4463-4472. doi: 10.1007/s12035-017-0660-x. Epub 2017 Jul 1.

PMID:
28669125
23.

Circadian clustering of spontaneous epileptic seizures emerges after pilocarpine-induced status epilepticus.

Pitsch J, Becker AJ, Schoch S, Müller JA, de Curtis M, Gnatkovsky V.

Epilepsia. 2017 Jul;58(7):1159-1171. doi: 10.1111/epi.13795. Epub 2017 May 24.

24.

Human Herpesvirus 6B Induces Hypomethylation on Chromosome 17p13.3, Correlating with Increased Gene Expression and Virus Integration.

Engdahl E, Dunn N, Niehusmann P, Wideman S, Wipfler P, Becker AJ, Ekström TJ, Almgren M, Fogdell-Hahn A.

J Virol. 2017 May 12;91(11). pii: e02105-16. doi: 10.1128/JVI.02105-16. Print 2017 Jun 1.

25.

Molecular rescue of Tsc1-ablated cortical tuber mice.

Robens B, Becker AJ.

Oncotarget. 2017 Jan 24;8(4):5678-5679. doi: 10.18632/oncotarget.14239. No abstract available.

26.

Synthesis and Evaluation of Amyloid β Derived and Amyloid β Independent Enhancers of the Peroxidase-like Activity of Heme.

Wißbrock A, Kühl T, Silbermann K, Becker AJ, Ohlenschläger O, Imhof D.

J Med Chem. 2017 Jan 12;60(1):373-385. doi: 10.1021/acs.jmedchem.6b01432. Epub 2016 Dec 15.

PMID:
27976903
27.

Micro-endoscopy of the human vas deferens: a feasibility study of a novel device in several ex vivo models.

Trottmann M, Sroka R, Braun C, Liedl B, Schaaf H, Graw M, Becker AJ, Stief CG, Khoder WY.

Andrology. 2017 Jan;5(1):75-81. doi: 10.1111/andr.12282. Epub 2016 Nov 17.

28.

Seizure control and cognitive improvement via immunotherapy in late onset epilepsy patients with paraneoplastic versus GAD65 autoantibody-associated limbic encephalitis.

Hansen N, Widman G, Witt JA, Wagner J, Becker AJ, Elger CE, Helmstaedter C.

Epilepsy Behav. 2016 Dec;65:18-24. doi: 10.1016/j.yebeh.2016.10.016. Epub 2016 Nov 15.

PMID:
27855355
29.

Non-paraneoplastic limbic encephalitis and central nervous HHV-6B reactivation: Causality or coincidence?

Niehusmann P, Widman G, Eis-Hübinger AM, Greschus S, Robens BK, Grote A, Becker AJ.

Neuropathology. 2016 Aug;36(4):376-80. doi: 10.1111/neup.12283. Epub 2016 Jan 15.

PMID:
27431532
30.

Minute amounts of hamartin wildtype rescue the emergence of tuber-like lesions in conditional Tsc1 ablated mice.

Robens BK, Grote A, Pitsch J, Schoch S, Cardoso C, Becker AJ.

Neurobiol Dis. 2016 Nov;95:134-44. doi: 10.1016/j.nbd.2016.07.006. Epub 2016 Jul 15.

PMID:
27425891
31.

Advances in the development of biomarkers for epilepsy.

Pitkänen A, Löscher W, Vezzani A, Becker AJ, Simonato M, Lukasiuk K, Gröhn O, Bankstahl JP, Friedman A, Aronica E, Gorter JA, Ravizza T, Sisodiya SM, Kokaia M, Beck H.

Lancet Neurol. 2016 Jul;15(8):843-856. doi: 10.1016/S1474-4422(16)00112-5. Review.

PMID:
27302363
32.

Evidence of a pathogenic role for CD8(+) T cells in anti-GABAB receptor limbic encephalitis.

Golombeck KS, Bönte K, Mönig C, van Loo KM, Hartwig M, Schwindt W, Widman G, Lindenau M, Becker AJ, Glatzel M, Elger CE, Wiendl H, Meuth SG, Lohmann H, Gross CC, Melzer N.

Neurol Neuroimmunol Neuroinflamm. 2016 Apr 29;3(3):e232. doi: 10.1212/NXI.0000000000000232. eCollection 2016 Jun.

33.

Astrocyte Intermediaries of Septal Cholinergic Modulation in the Hippocampus.

Pabst M, Braganza O, Dannenberg H, Hu W, Pothmann L, Rosen J, Mody I, van Loo K, Deisseroth K, Becker AJ, Schoch S, Beck H.

Neuron. 2016 May 18;90(4):853-65. doi: 10.1016/j.neuron.2016.04.003. Epub 2016 May 5.

34.

Abundance of LRP12 C-rs9694676 allelic promoter variant in epilepsy-associated gangliogliomas.

Robens BK, Gembé E, Fassunke J, Becker AJ, Schoch S, Grote A.

Life Sci. 2016 Jun 15;155:70-5. doi: 10.1016/j.lfs.2016.01.049. Epub 2016 Apr 30.

PMID:
27142828
35.

Neuropathological signs of inflammation correlate with mitochondrial DNA deletions in mesial temporal lobe epilepsy.

Volmering E, Niehusmann P, Peeva V, Grote A, Zsurka G, Altmüller J, Nürnberg P, Becker AJ, Schoch S, Elger CE, Kunz WS.

Acta Neuropathol. 2016 Aug;132(2):277-88. doi: 10.1007/s00401-016-1561-1. Epub 2016 Mar 18.

PMID:
26993140
36.

Identification of Synaptotagmin 10 as Effector of NPAS4-Mediated Protection from Excitotoxic Neurodegeneration.

Woitecki AM, Müller JA, van Loo KM, Sowade RF, Becker AJ, Schoch S.

J Neurosci. 2016 Mar 2;36(9):2561-70. doi: 10.1523/JNEUROSCI.2027-15.2016.

37.

Drug use among men with unfulfilled wish to father children: a retrospective analysis and discussion of specific drug classes.

Pompe SV, Strobach D, Stief CG, Becker AJ, Trottmann M.

Pharmacoepidemiol Drug Saf. 2016 Jun;25(6):668-77. doi: 10.1002/pds.3986. Epub 2016 Mar 1.

PMID:
26932728
38.

Systems genetics identifies a convergent gene network for cognition and neurodevelopmental disease.

Johnson MR, Shkura K, Langley SR, Delahaye-Duriez A, Srivastava P, Hill WD, Rackham OJ, Davies G, Harris SE, Moreno-Moral A, Rotival M, Speed D, Petrovski S, Katz A, Hayward C, Porteous DJ, Smith BH, Padmanabhan S, Hocking LJ, Starr JM, Liewald DC, Visconti A, Falchi M, Bottolo L, Rossetti T, Danis B, Mazzuferi M, Foerch P, Grote A, Helmstaedter C, Becker AJ, Kaminski RM, Deary IJ, Petretto E.

Nat Neurosci. 2016 Feb;19(2):223-32. doi: 10.1038/nn.4205. Epub 2015 Dec 21.

39.

An innovative technique of robotic-assisted/laparoscopic re-pyeloplasty in horseshoe kidney in patients with failed previous pyeloplasty for ureteropelvic junction obstruction.

Khoder WY, Alghamdi A, Schulz T, Becker AJ, Schlenker B, Stief CG.

Surg Endosc. 2016 Sep;30(9):4124-9. doi: 10.1007/s00464-015-4678-8. Epub 2015 Dec 16.

PMID:
26675936
40.

LRP12 silencing during brain development results in cortical dyslamination and seizure sensitization.

Grote A, Robens BK, Blümcke I, Becker AJ, Schoch S, Gembé E.

Neurobiol Dis. 2016 Feb;86:170-6. doi: 10.1016/j.nbd.2015.11.021. Epub 2015 Dec 2.

PMID:
26639854
41.

Gene expression variance in hippocampal tissue of temporal lobe epilepsy patients corresponds to differential memory performance.

Bungenberg J, Surano N, Grote A, Surges R, Pernhorst K, Hofmann A, Schoch S, Helmstaedter C, Becker AJ.

Neurobiol Dis. 2016 Feb;86:121-30. doi: 10.1016/j.nbd.2015.11.011. Epub 2015 Nov 26.

PMID:
26631617
42.

Probe-based confocal laser endomicroscopy (pCLE): a preclinical investigation of the male genital tract.

Trottmann M, Sroka R, Stepp H, Liedl B, Becker AJ, Stief CG, Kölle S.

Lasers Med Sci. 2016 Jan;31(1):57-65. doi: 10.1007/s10103-015-1828-0. Epub 2015 Oct 30.

PMID:
26519156
43.

Zinc regulates a key transcriptional pathway for epileptogenesis via metal-regulatory transcription factor 1.

van Loo KM, Schaub C, Pitsch J, Kulbida R, Opitz T, Ekstein D, Dalal A, Urbach H, Beck H, Yaari Y, Schoch S, Becker AJ.

Nat Commun. 2015 Oct 26;6:8688. doi: 10.1038/ncomms9688.

44.

Investigation of GRIN2A in common epilepsy phenotypes.

Lal D, Steinbrücker S, Schubert J, Sander T, Becker F, Weber Y, Lerche H, Thiele H, Krause R, Lehesjoki AE, Nürnberg P, Palotie A, Neubauer BA, Muhle H, Stephani U, Helbig I, Becker AJ, Schoch S, Hansen J, Dorn T, Hohl C, Lüscher N; Epicure consortium; EuroEPINOMICS-CoGIE consortium, von Spiczak S, Lemke JR.

Epilepsy Res. 2015 Sep;115:95-9. doi: 10.1016/j.eplepsyres.2015.05.010. Epub 2015 Jun 2.

PMID:
26220384
45.

Extending the phenotypic spectrum of RBFOX1 deletions: Sporadic focal epilepsy.

Lal D, Pernhorst K, Klein KM, Reif P, Tozzi R, Toliat MR, Winterer G, Neubauer B, Nürnberg P, Rosenow F, Becker F, Lerche H, Kunz WS, Kurki MI, Hoffmann P, Becker AJ, Perucca E, Zara F, Sander T, Weber YG.

Epilepsia. 2015 Sep;56(9):e129-33. doi: 10.1111/epi.13076. Epub 2015 Jul 15.

46.

Relevance of hippocampal integrity for memory outcome after surgical treatment of mesial temporal lobe epilepsy.

Witt JA, Coras R, Schramm J, Becker AJ, Elger CE, Blümcke I, Helmstaedter C.

J Neurol. 2015 Oct;262(10):2214-24. doi: 10.1007/s00415-015-7831-3. Epub 2015 Jul 3.

PMID:
26138541
47.

Calcium-binding proteins in focal cortical dysplasia.

Kuchukhidze G, Wieselthaler-Hölzl A, Drexel M, Unterberger I, Luef G, Ortler M, Becker AJ, Trinka E, Sperk G.

Epilepsia. 2015 Aug;56(8):1207-16. doi: 10.1111/epi.13053. Epub 2015 Jun 17.

48.

[Conservative therapy of erectile dysfunction].

Trottmann M, Marcon J, Pompe S, Strobach D, Becker AJ, Stief CG.

Urologe A. 2015 May;54(5):668-75. doi: 10.1007/s00120-015-3794-3. Review. German.

PMID:
25987332
49.

Temporal lobe epilepsy: a unique window into living human brain epigenetic gene regulation.

Grote A, Schoch S, Becker AJ.

Brain. 2015 Mar;138(Pt 3):509-11. doi: 10.1093/brain/awu386. No abstract available.

50.

Systems genetics identifies Sestrin 3 as a regulator of a proconvulsant gene network in human epileptic hippocampus.

Johnson MR, Behmoaras J, Bottolo L, Krishnan ML, Pernhorst K, Santoscoy PLM, Rossetti T, Speed D, Srivastava PK, Chadeau-Hyam M, Hajji N, Dabrowska A, Rotival M, Razzaghi B, Kovac S, Wanisch K, Grillo FW, Slaviero A, Langley SR, Shkura K, Roncon P, De T, Mattheisen M, Niehusmann P, O'Brien TJ, Petrovski S, von Lehe M, Hoffmann P, Eriksson J, Coffey AJ, Cichon S, Walker M, Simonato M, Danis B, Mazzuferi M, Foerch P, Schoch S, De Paola V, Kaminski RM, Cunliffe VT, Becker AJ, Petretto E.

Nat Commun. 2015 Jan 23;6:6031. doi: 10.1038/ncomms7031.

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